ZMP

chrna4

Ensembl ID:

ENSDARG00000058393

ZFIN ID:

ZDB-GENE-090505-3

Description:

cholinergic receptor, nicotinic, alpha 4 [Source:RefSeq peptide;Acc:NP_001041528]

Human Orthologue:

CHRNA4

Human Description:

cholinergic receptor, nicotinic, alpha 4 [Source:HGNC Symbol;Acc:1958]

Mouse Orthologue:

Chrna4

Mouse Description:

cholinergic receptor, nicotinic, alpha polypeptide 4 Gene [Source:MGI Symbol;Acc:MGI:87888]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa31820	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
e47	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa31820

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000104115	Essential Splice Site	85	627	3	6

Genomic Location (Zv9):

Chromosome 11 (position 13219127)

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCAGGATGAGAAGAATCAGATGATGACCACAAATGTCTGGGTGAAGCAGG[T/A]ATGTTTTCATCAAAAAAAAAAAAAAAAACGCCCATAATTAGACATTAATG

Long Flanking Sequence:

TTTTAAATAGGGTAATTTGTAATCTGTAATCTATTACATTTTCAAAGTAACCTTCCCAACACTGGTTGTGTCACTGCTGTCTAAATGTGAGAAAATTTTTATTTTGGCATAAACTATGCCATTAATGATTGAGCTTTTAATACTTTAAACACACACAAAAAATGCTTTGCCCTTTTTAGTGTTTTCCATGAGCCCAGCTCATGCCCATGCGGAAGAAAGACTCCTCCAGTCTTTGTTCATCAACTACAACAAGCTTTCACGTCCAGTAGCAAACATCTCTGATGTGGTTCTGGTCCATTTCGGCTTGTCCATTGCTCAGCTCATTGATGTGGTGAGTCTCAGATATCCTACTTTTTTCTTTTCCTCTAAAACGTACAGTCTCACCATAAAGTCACTTTCCCTTTTTTTATTACTCTCTTCTGTATGGAAATCTCACTATGCTTCATAAAACCAGGATGAGAAGAATCAGATGATGACCACAAATGTCTGGGTGAAGCAGG[T/A]ATGTTTTCATCAAAAAAAAAAAAAAAAACGCCCATAATTAGACATTAATGAGATTTTTAATTGGAACTGGGCTCTTGTTGCTTCACTCTCCACCCCTGTCATACATGCTGGTTGTGAGCGGTGATGAGCGCACATGTTTCCCTGCAGGAGTGGAACGACTACAAGCTGCGCTGGAACCCAGAGGAGTATGAGAATGTCACCTCCATCAGGATCCCCTCTGAGATCATCTGGAGACCGGATATTGTGCTCTATAACAAGTGTGTGAGGCCTTTTACAAATCCGGAATTTAGCCAAATCCATTTCTTAAGATCGACATCATCAAACACTGTTAACCTCCCACCGTTCCAGCATTGTGAAAGGTTTCCGCAATTCGGTTTGATTTCATTCTTTCACTTTGGAGGTCTGTTAATGTTTTTTTCCTACTCAATCTCACGGCAAATCAGAAGTTTTTGATTTATTTTAAATCCAAGACAGAGTTTCGGACATGAGCAATATAATGA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

e47

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000104115	Nonsense	94	627	4	6

Genomic Location (Zv9):

Chromosome 11 (position 13219300)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	12935908
GRCz11	11	12993567

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GATGAGCGCACATGTTTCCCTGCAGGAGTGGAACGACTACAAGCTGCGCT[G/A]GAACCCAGAGGAGTATGAGAATGTCACCTCCATCAGGATCCCCTCTGAGA

Long Flanking Sequence:

TTTTAGTGTTTTCCATGAGCCCAGCTCATGCCCATGCGGAAGAAAGACTCCTCCAGTCTTTGTTCATCAACTACAACAAGCTTTCACGTCCAGTAGCAAACATCTCTGATGTGGTTCTGGTCCATTTCGGCTTGTCCATTGCTCAGCTCATTGATGTGGTGAGTCTCAGATATCCTACTTTTTTCTTTTCCTCTAAAACGTACAGTCTCACCATAAAGTCACTTTCCCTTTTTTTATTACTCTCTTCTGTATGGAAATCTCACTATGCTTCATAAAACCAGGATGAGAAGAATCAGATGATGACCACAAATGTCTGGGTGAAGCAGGTATGTTTTCATCAAAAAAAAAAAAAAAAACGCCCATAATTAGACATTAATGAGATTTTTAATTGGAACTGGGCTCTTGTTGCTTCACTCTCCACCCCTGTCATACATGCTGGTTGTGAGCGGTGATGAGCGCACATGTTTCCCTGCAGGAGTGGAACGACTACAAGCTGCGCT[G/A]GAACCCAGAGGAGTATGAGAATGTCACCTCCATCAGGATCCCCTCTGAGATCATCTGGAGACCGGATATTGTGCTCTATAACAAGTGTGTGAGGCCTTTTACAAATCCGGAATTTAGCCAAATCCATTTCTTAAGATCGACATCATCAAACACTGTTAACCTCCCACCGTTCCAGCATTGTGAAAGGTTTCCGCAATTCGGTTTGATTTCATTCTTTCACTTTGGAGGTCTGTTAATGTTTTTTTCCTACTCAATCTCACGGCAAATCAGAAGTTTTTGATTTATTTTAAATCCAAGACAGAGTTTCGGACATGAGCAATATAATGATATTTTTGTCTTTTAACATTTTTTTATTTTTTTACATTTTTGCTATTTAAAGCTGCTTTACAGCTGAATTGGAACACATTTTAAAGTTGATGATATATTTGCATTTCATAATTGCAACTTTATTTTTATTTTTTTCTTTATTATATATAAAAAAAAATTAGACAAGTCATTGG

Associated Phenotype:

Not determined