Busch Lab

ZMP

chrna4

Ensembl ID:
ENSDARG00000070724
ZFIN ID:
ZDB-GENE-090505-3
Description:
cholinergic receptor, nicotinic, alpha 4 [Source:RefSeq peptide;Acc:NP_001041528]
Human Orthologue:
CHRNA4
Human Description:
cholinergic receptor, nicotinic, alpha 4 [Source:HGNC Symbol;Acc:1958]
Mouse Orthologue:
Chrna4
Mouse Description:
cholinergic receptor, nicotinic, alpha polypeptide 4 Gene [Source:MGI Symbol;Acc:MGI:87888]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa31819 Essential Splice Site Available for shipment Available now
e47 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa31819
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018614 Essential Splice Site 85 627 3 6
Genomic Location (Zv9):
Chromosome 11 (position 13051669)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12936078
GRCz11 11 12993737
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGGATGAGAAGAATCAGATGATGACCACAAATGTCTGGGTGAAGCAGG[T/A]ATGTTTTCATCTAAAAAAAAAAAAACGCCCATAATTAGACATTAATGAGA
Long Flanking Sequence:
CGTTATTGGATGTCAAAATAACATTCTCCTGAAATGCTGGCAACCTAAATCTATAAATGTCTTATGATGTTGTGTGTCTGCTGTCTAAATGTGAGAAAATTTTTATTTTGGCCAGAACTATGCCTTTAATGATTGAGCTTTTGAAACTTTAAACACACAAAAAATGCTTTGCCCTTTAGTGTTTTCCATGAGCCCAGCTCATGCCCATGCGGAAGAAAGACTCCTCCAGTCTTTGTTCATCAACTACAACAAGCTTTCACGTCCAGTAGCAAACATCTCTGATGTGGTTCTGGTCCATTTCGGCTTGTCCATTGCTCAGCTCATTGATGTGGTGAGTCTCAGATATCCTACTTTTTTCTTTTCCTCTAAATCGTACAGTCTCACCATAAAGTCACTTTCCCTTTTTTTATTACTCTCTTCTGTATGGAAATCTCACTTTGCTTCATAAAACCAGGATGAGAAGAATCAGATGATGACCACAAATGTCTGGGTGAAGCAGG[T/A]ATGTTTTCATCTAAAAAAAAAAAAACGCCCATAATTAGACATTAATGAGATTTTTAATTGGAACTGGGCTCTTGTTGCTTCACTCTCCACCCCTGTCATACATGCTGGTTGTGAGCGGTGATGAGCGCACATGTTTCCCTGCAGGAGTGGAACGACTACAAGCTGCGCTGGAACCCAGAGGAGTATGAGAATGTCACCTCCATCAGGATCCCCTCTGAGATCATCTGGAGACCGGATATTGTGCTCTATAACAAGTGTGTGAGGCCTTTTACAAATCCGGAATTTAGCCAAATCCATTTCTTAAGATCGACATCATCAAACACTGTTAACCTCCCACCGTTCCAGCATTGTGAAAGGTTTCCGCAATTCGGTTTGATTTCATTCTTTCACTTTGGAGGTCTGTTAATGTTTTTTTCCTACTCAATCTCACGGCAAATCAGAAGTTTTTGATTTATTTTAAATCCAAGACAGAGTTTCGGACATGAGCAATATGATGATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
e47
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018614 Nonsense 94 627 4 6
Genomic Location (Zv9):
Chromosome 11 (position 13051499)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12935908
GRCz11 11 12993567
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGAGCGCACATGTTTCCCTGCAGGAGTGGAACGACTACAAGCTGCGCT[G/A]GAACCCAGAGGAGTATGAGAATGTCACCTCCATCAGGATCCCCTCTGAGA
Long Flanking Sequence:
GCCCTTTAGTGTTTTCCATGAGCCCAGCTCATGCCCATGCGGAAGAAAGACTCCTCCAGTCTTTGTTCATCAACTACAACAAGCTTTCACGTCCAGTAGCAAACATCTCTGATGTGGTTCTGGTCCATTTCGGCTTGTCCATTGCTCAGCTCATTGATGTGGTGAGTCTCAGATATCCTACTTTTTTCTTTTCCTCTAAATCGTACAGTCTCACCATAAAGTCACTTTCCCTTTTTTTATTACTCTCTTCTGTATGGAAATCTCACTTTGCTTCATAAAACCAGGATGAGAAGAATCAGATGATGACCACAAATGTCTGGGTGAAGCAGGTATGTTTTCATCTAAAAAAAAAAAAACGCCCATAATTAGACATTAATGAGATTTTTAATTGGAACTGGGCTCTTGTTGCTTCACTCTCCACCCCTGTCATACATGCTGGTTGTGAGCGGTGATGAGCGCACATGTTTCCCTGCAGGAGTGGAACGACTACAAGCTGCGCT[G/A]GAACCCAGAGGAGTATGAGAATGTCACCTCCATCAGGATCCCCTCTGAGATCATCTGGAGACCGGATATTGTGCTCTATAACAAGTGTGTGAGGCCTTTTACAAATCCGGAATTTAGCCAAATCCATTTCTTAAGATCGACATCATCAAACACTGTTAACCTCCCACCGTTCCAGCATTGTGAAAGGTTTCCGCAATTCGGTTTGATTTCATTCTTTCACTTTGGAGGTCTGTTAATGTTTTTTTCCTACTCAATCTCACGGCAAATCAGAAGTTTTTGATTTATTTTAAATCCAAGACAGAGTTTCGGACATGAGCAATATGATGATATTTTTGTCTTTTAACTTTTTTTTTTATTTTTTTTTTTGCTATTTGAAGCTGCTTTACAGCTGAATTTGAACACATTTTAAAGTTGATGATATATTTGCATTTCATAATTGCAACTTTATTATTTAGTTATTTTTTCTTTATTATATAAAATAAAATTAGACATGTCGTTGG
Associated Phenotype:
Not determined