Busch Lab

ZMP

cltca

Ensembl ID:
ENSDARG00000043493
ZFIN ID:
ZDB-GENE-030131-2299
Description:
clathrin, heavy polypeptide a [Source:RefSeq peptide;Acc:NP_001005391]
Human Orthologue:
CLTC
Human Description:
clathrin, heavy chain (Hc) [Source:HGNC Symbol;Acc:2092]
Mouse Orthologue:
Cltc
Mouse Description:
clathrin, heavy polypeptide (Hc) Gene [Source:MGI Symbol;Acc:MGI:2388633]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa34925 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa41680 Nonsense Mutation detected in F1 DNA Not yet available
sa21757 Nonsense Available for shipment Available now
sa21756 Essential Splice Site Available for shipment Available now
sa16707 Nonsense Available for shipment Available now
sa14787 Nonsense Available for shipment Available now
sa31785 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa34925
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Essential Splice Site 15 1680 2 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 29037542)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28469136
GRCz11 10 28355761
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGTGTTTAGTGTGCTCATTCAAATGAAATAAAACTGTTCTCTTTTCCTA[G/T]CTCCAAAATTTGGGGATCAACCCAGCCAACATTGGGTTCAGCACCCTGAC
Long Flanking Sequence:
CTTGTGTCTGCTCTTTGTGTGTCCCTGAGATAAATTCCTCAAGGCTTTTTCAGATAGTAAAGCCATGTGGTTGACTCGGTGTAGGGAAAAAAGGATTTGCTGCTTCTATGCCACATTTAATTACTGTTCTTATTACTAGAAAGGCTGATCTCATAATACTCTTCAACACACACAATTACTGCTGAAATGTAGTGAAACTACAAAAATTATTTGCTGTTACGGTTTCATCTTTCTGCCTTGTAAATCATGTTTGAGATCCATTTAATCTTCAGTGTGGAACACTGTCATTGATTTTTATTAAAAGATTCATTCAGAAAGCAGTTCACAGGGTCAGAGAGACACCTGACCTGATATCACTTAAGAAATAAAATCAAATTATCTCAGTATTCTTGACTCTTAAAAAGGACGAAATGGAAATAAAAATGAGAATTGTATTAATTAGATAAAAAAAAGTGTTTAGTGTGCTCATTCAAATGAAATAAAACTGTTCTCTTTTCCTA[G/T]CTCCAAAATTTGGGGATCAACCCAGCCAACATTGGGTTCAGCACCCTGACAATGGAATCGGATAAGTTCATCTGTGTCCGGGAGAAGGTTGGAGAACAGGCGCAGGTGGTGATCATTGATATGGCGGACCCAAACACCCCCATCCGCAGGCCCATCTCTGCAGATAGTGCCATCATGAACCCTGCGAGCAAAGTCATTGCCCTCAAAGGTAGGAGATCTAGATTGTTAGTGCATTAGCTATTTGTAGTAACCTAATTGTAATGACTAGTTGACAACAGAATCATAGAACTGATCCAATTGTTGTTTTAAACTAGAATTTAAGTTGTCTTGTTTTCTTAGCCTCATTCATTCACCCAGAATCTCTTTTTAGTTAAAATTATGCTATACCTATTTCTTAAGCAAATGTTTTTGCATTTTCCCTCATTATAGGCTACATCTTATCTTAAAGTAACATGATATGTTGTGTATTTTTTGTCATGCAGCCATAATTGCTTTGTCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41680
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Nonsense 221 1680 4 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 29032652)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28464246
GRCz11 10 28350871
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAAAATGGAGGGAAACACTGAAGAATCCACTCTCTTCTGTTTCGCTGTG[C/T]GAGGTCAGGCAGGCGGAAAGGTGCGTTTCCATATGCATGCATACATTTGT
Long Flanking Sequence:
AATCATTTTAAAGAACCGTTCTGGATTGTTGGTCTAGAATTATTTTGGGTTACGCTTTAGTTTAGGTCACAGTTCACAGTATTAACAAACCATTAACTGACACTACTAGCTTAATAAACTACTTATAAGCTGTTTGTTAATAGTTAGTAAGGTAGAAGATGGGTAGGATTAGGAATTCAGAATAGTTTACAACTACTAATGAACTGTTAACATCCTAATAAAAGCCAGTAGTTAATAACACGAATAGTGACCTAAACTAAAGTGTACCTTATTTTACTTTGTCTGTCATTCAATTAAACGTTGGATATTGAATCAAAGACACCCCCCCCAAATCTCAAAACTGTTCTTTCATTTTGTAGCAAAACAGAGTTGTTGGAGCCATGCAGCTCTACTCTGTTGATAGGAAGGTGTCACAGCCTATTGAGGGGCACGCCGCTGGCTTTGGTCAATTCAAAATGGAGGGAAACACTGAAGAATCCACTCTCTTCTGTTTCGCTGTG[C/T]GAGGTCAGGCAGGCGGAAAGGTGCGTTTCCATATGCATGCATACATTTGTACATTTCACGAGTGCATCTAAGAATTGACATGCATTTTTTTTCGTTGCCGTAGTATTAAAAACTAATTTTTACTTTTAATCAAAGCAGAACAAGGAACTTTTACCTACATAAGGACATTGAAGCATCAGTCTGTTGCATGTTTTTTGTCATAAATGCAAGCACAAGCTTTTGTTCAAAGTGACTTACAATTGAGTTACTGCATATAATCACTTTGACCTGATATGTTTCAATCCAATAAAAAGACAAGTTATTTAGTTATCAGTATTCCCAAGACAGTTATCTAAGAAACAGTGGAAGTAGAGCTGGGCAATATGGCAAAAATTAAACCCTGATAAATTATTTTTCAAACTGAACAACAATATATATTTCGATATCAGTTGTTTATTCTTTCAGATTTAAAATAGTATCCCAACAGTGACTAAAGATGCAAATTAAAGGATCTGTTAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21757
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Nonsense 603 1680 12 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 29014756)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28446350
GRCz11 10 28332975
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTCAAGCACAGTGGTCTCTTACAGGTTGCAGATGCCATCCTAGGAAAC[C/T]AGATGTTCACCAACTACGATCGTGCCCACATCGCCCAACTGTGTGAGAAA
Long Flanking Sequence:
TTTGCCTACCTTGTTTCGAGACTTCCGGTCTCATTCACTTCCATTGATTTCAGGCGTTAAAAACAGCTGGTTATGCTGCTTAATGATGCAAACTTGTATTTTCTTATTATTATTCTTTTTATAAATAGTCACAAACACACTTATGTGTAGAGCAAGTAATTTTACTGACATTTATTTTTCCTTGTCATTTCTCCTATAGGCAACTAAATAAGAAGTACTAAAACAATCGCAAAATACAAACACACTTCCGCATTGCAGAATACAGTCATTAATCTTGTGCTTTTGCCATGCCACTGCCTGAATCTCAGGTTGTTTTAAAATTGTTATTCTCAACATGTCCAGTTGTAATGTTGGCTAATATGTAATTACTGTGGTCAGCATTGTCCAAAATAAAAAACAGCAACACCCCAGTCCTCATCATCGCATTAGTTATTTTACCATTAGTCACTATTTTCAAGCACAGTGGTCTCTTACAGGTTGCAGATGCCATCCTAGGAAAC[C/T]AGATGTTCACCAACTACGATCGTGCCCACATCGCCCAACTGTGTGAGAAAGCAGGACTTCTTCAGAGAGCTTTAGAGCATTACACCGACTTGTATGACATCAAACGAGCTGTCGTGCACACACACCTGCTCAACCCGGAGGTACACAACAAGTCTTTACATTCATGCCCAATTAAAGTGCAACCACCTGCCTTTTCCTTTTGTTTCTCATGGTATTGGTCTCTGCTAATGTCTGCAGTGGCTGGTCAACTACTTTGGCTCTCTGTCAGTGGAGGACTCTCTGGAGTGTCTGAGGGCCATGCTGTCTGCTAACATCAGACAGAATCTCCAGATCTGCGTCCAGGTGGCGTCCAAGTATCACGAGCAGCTGAGCACACAGTCCCTCACCGAGCTCTTTGAGTCGTTCAAGAGTTTTGAGGGTAAGAAGTAGATCCAGCATGATTCAATTATTCTGTCTGTGTTATTGTCTGCTATCATGCAAAGCTTTCACATTCAAGGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21756
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Essential Splice Site 649 1680 12 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 29014614)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28446208
GRCz11 10 28332833
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATGACATCAAACGAGCTGTCGTGCACACACACCTGCTCAACCCGGAGG[T/C]ACACAACAAGTCTTTACATTCATGCCCAATTAAAGTGCAACCACCTGCCT
Long Flanking Sequence:
ATGTGTAGAGCAAGTAATTTTACTGACATTTATTTTTCCTTGTCATTTCTCCTATAGGCAACTAAATAAGAAGTACTAAAACAATCGCAAAATACAAACACACTTCCGCATTGCAGAATACAGTCATTAATCTTGTGCTTTTGCCATGCCACTGCCTGAATCTCAGGTTGTTTTAAAATTGTTATTCTCAACATGTCCAGTTGTAATGTTGGCTAATATGTAATTACTGTGGTCAGCATTGTCCAAAATAAAAAACAGCAACACCCCAGTCCTCATCATCGCATTAGTTATTTTACCATTAGTCACTATTTTCAAGCACAGTGGTCTCTTACAGGTTGCAGATGCCATCCTAGGAAACCAGATGTTCACCAACTACGATCGTGCCCACATCGCCCAACTGTGTGAGAAAGCAGGACTTCTTCAGAGAGCTTTAGAGCATTACACCGACTTGTATGACATCAAACGAGCTGTCGTGCACACACACCTGCTCAACCCGGAGG[T/C]ACACAACAAGTCTTTACATTCATGCCCAATTAAAGTGCAACCACCTGCCTTTTCCTTTTGTTTCTCATGGTATTGGTCTCTGCTAATGTCTGCAGTGGCTGGTCAACTACTTTGGCTCTCTGTCAGTGGAGGACTCTCTGGAGTGTCTGAGGGCCATGCTGTCTGCTAACATCAGACAGAATCTCCAGATCTGCGTCCAGGTGGCGTCCAAGTATCACGAGCAGCTGAGCACACAGTCCCTCACCGAGCTCTTTGAGTCGTTCAAGAGTTTTGAGGGTAAGAAGTAGATCCAGCATGATTCAATTATTCTGTCTGTGTTATTGTCTGCTATCATGCAAAGCTTTCACATTCAAGGAAATGTAACTAAAAGGAAACATTTTAGTTTATTTTGCAATTTTGTAGGTTTTTCCAAATAAGATTTTTATGCACTTTAGTCTTTTTTTTTTGTTCGTTTTAAAGTTAAAATAAAAGTAGAAAATTTAAATATAAATTAAATGATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16707
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Nonsense 943 1680 18 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 29004866)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28436460
GRCz11 10 28323085
KASP Assay ID:
2260-3348.1 (used for ordering genotyping assays)
KASP Sequence:
TTTTGATTTTTCTCTACAGGTTTGCAATGAGAACTCGCTGTTCAAGAGTT[T/A]GTCCCGCTATCTKGTGCGCCGCAGGGACCCYGAGCTMTGGGCCAGTGTGC
Long Flanking Sequence:
TTTGTGTTAACAAAAGTTTTTTTTTTTCTGTTATTTTAACCCAATGTTTACCTCCCTGTTTACATGTTTCAATTGAAATTAAGTTGCACATTGAACTAAGCTGCACATCGAAAGACGCTTTAGATTACTTTTACATGTTTTCTCTTTTGTAGACTGAAGCTGTTGTTGCCCTGGCTGGAGTCTCGTATCCACGAGGGCTGTGAGGAGCCAGCTACCCACAATGCCCTGGCCAAGATCTACATCGACAGCAACAACAACCCTGAACGCTTCCTGCGGGAGAACCCATACTACGATAGCCGCGTGGTGGGGAAATACTGCGAAAAACGAGACCCTCATCTGGCCTGTGTGGCCTATGAGAGAGGAACGTGTGACCAGGAGCTGATCAACGTCAGTAATGCTTCAGCATGCATGAGCTTAAGTGCAGCCATTCAGCATGAGAATTGATCTTGATTTTGATTTTTCTCTACAGGTTTGCAATGAGAACTCGCTGTTCAAGAGTT[T/A]GTCCCGCTATCTGGTGCGCCGCAGGGACCCTGAGCTATGGGCCAGTGTGCTTCTGGAGACCAACCCCTTCAGGAGGCCCCTTATTGACCAGGTACACAAATATGTTACATTCATCTCTTACAATAGATTAACATGGCTCATGCAGAAACATAATGATTATTCATCTCTTTCTATTCATTATTGGTGAAATGGACTATTTGCTGAATTAAATAGAATGTATTTATTATGACCAATAAACTTCTCCATCTGGAATTGACTTGAGTTTGTTACAATGCATTTTGTTATTTTTAATAATAATAAATAATAATAGTAATAGGGAAGAAATTACCAAGGTTTCTGCTGGGTCTTAAAATGAATTTCAAAAACTAAATTTTAGCCCTTAAAACGTCCTAATTTCACTGAAATATTGTCTTGTAGGTCTTAAATCCTTTTAAACAAGTTTTGATTTTCATCTATATCCATGTCTCCAATCAACATAAGTTCATCTCAAAAACACTTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14787
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Nonsense 1043 1680 20 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 29002853)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28434447
GRCz11 10 28321072
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGCTCATCCTAACAGCCATCAAAGCTGACCGTACTCGGGTCATGGAGTA[C/A]ATCAACCGCCTGGACAACTAYGATGCCCCAGACATCGCCAACATCGCCAT
Long Flanking Sequence:
TTTAGTATTTGTCTTTCCTAACAGCTTTAAGTAATTTAGTTCTGTTTATTTAGTTATTGTGAAGACCAAGCTCAAAACATAATTACATATTAATTTAAATAATGACACAGTCTGCAATTTAACAATAAATGATGAGGGAAAAATTCTTTGCCATAATAATATCAGAAACTTTATACATGACTGCATTCATTTTTATGGCTGCTCAAAAAAGGAAGTATTATATAGTATTAATAAAAGCTGGACATACTCCATTCGCCATATTGTCATTTTCATATGACCTACCAACATCGAAAAGAGTTTTATTAAAAACATCAGAGAGTTTTCATGACAGAAGTGTTCACAGAGAAATGACAGTGACCGGACAAAAACAAAGATGATAAAGGAATTAAAACTATAAATGGGGTTTAACTGACTTCCAATCTTCATCCCATACCCAGAAACCTGCAGAACCTGCTCATCCTAACAGCCATCAAAGCTGACCGTACTCGGGTCATGGAGTA[C/A]ATCAACCGCCTGGACAACTACGATGCCCCAGACATCGCCAACATCGCCATCAGCAGCGAGCTGTTTGAGGAGGCCTTCGCCATCTTCAAGAAATTCGATGTCAACACCTCTGCAGTGCAGGTTTGCTCTTCAGCCACAATATTTATACTAGATATCAGCTTATTATTAAAAGCGTTTTTTAATAGTACGTAATATTACAATATTTATTAATATCTCGAATTGTATCTTTATATTTCAGTTTTCATTTTAGCTAATGTTTATTATTTTAGTTTTGATACTATAATATTATCTTTATTTTAATAGAATATTTATAATTGCTTTGACTTTTTTTATTTATTAAACAGCAGTTAAAGAATGAGCTAATGCATCTTGTCATCCTCAGGTTCTGATCGAGCACATTGGTAATCTGGACCGGGCCTATGAGTTTGCGGAGCGCTGCAATGAACCTGCGGTGTGGAGTCAACTGGCCAAGGCTCAGCTTCAGAAGGGTCTCGTCAAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31785
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063849 Essential Splice Site 1535 1680 28 31

The following transcripts of ENSDARG00000043493 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 28997081)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 28428675
GRCz11 10 28315300
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCGCTGGAAGCAGAGCGTGGAGCTGTGCAAGAAAGACAAGCTCTACAAG[G/A]TGAACCTTCACTCCTGTTACTCAAGCAATCAGTAAATGTGCATCTAATCA
Long Flanking Sequence:
ACTAAGGTCACCACATCAAATACTGGCTGGGGTATGTAAAACATAGTTTTTGGTTTTTACAAATGTGCAAATGCTGATCAGCATTGTCATGTAGGGAAAAACATTACTTTTTTTTCTTTTTCTTTTTTTGCTAGATTTTAGTTTGTTTGAAACTCAATATCAAATGAAAAAAAAAAGGTGGATAGAAAAAAACAGATTCACGACTTCTAAGAATCGATATAAAATCAACATTATTTTTTAAATACAATATACAGAGAAGTTTGTTTTTTTGGCTCAGCACTACTGTTACAGTCTAATATCTCATAACCCATTCCCCCATCTTATCGCAGGCCCTCAGGACGTCCATAGACGCGTACGATAACTTCGACAACATCTCTCTGGCTCAGCGTCTGGAGAAACACGAGTTAATTGAGTTCAGGAGAATCGCTGCTTACCTCTTCAAGGGGAACAACCGCTGGAAGCAGAGCGTGGAGCTGTGCAAGAAAGACAAGCTCTACAAG[G/A]TGAACCTTCACTCCTGTTACTCAAGCAATCAGTAAATGTGCATCTAATCATGGCCTTGACAGATATGTGTGTGTGTTTTCTCAGGATGCCATGCAATATGCATCGGAGTCAAAGGACACAGAGCTGGCCGAGGAGCTGCTGCAGTGGTTCCTGGATGAGAATAAGAAGGAGTGTTTTGCCGCCTGCCTCTTCACCTGCTACGATCTGCTCCGGCCTGACGTGGTGCTGGAGACATCCTGGAGGAACAACATCATGGACTTCGCCATGCCGTACTTCATCCAGGTCATGAGGGAATACCTCAGCAAGGTGAGGACAGGCTAAAAGAATGCATTATAAACCACACATTTTAAATAAGAAATCACTTCCAAATGTATTTTATTAACATTTACATATATTTAGTTATATATGAACAAGTATATTTATTGAATTTTTATTAACAAAACTTGGAGACCCCATTCAATGTTCGTACTGCACAACAATAAAACACATTTTACTGGACT
Associated Phenotype:
Not determined