Busch Lab

ZMP

si:ch211-176f1.1

Ensembl ID:
ENSDARG00000006301
ZFIN ID:
ZDB-GENE-070912-156
Description:
Novel protein similar to human Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (RAPH
Human Orthologue:
RAPH1
Human Description:
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:HGNC Symbol;Acc:14436]
Mouse Orthologue:
Raph1
Mouse Description:
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Gene [Source:MGI Symbol;Acc:MGI:1924

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa31706 Nonsense Available for shipment Available now
sa8384 Nonsense Mutation detected in F1 DNA Not yet available
sa34583 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa38727 Nonsense Mutation detected in F1 DNA Not yet available
sa34582 Nonsense Mutation detected in F1 DNA Not yet available
sa38726 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa31706
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061156 Nonsense 19 1346 1 14
ENSDART00000146597 Nonsense 19 670 1 13

The following transcripts of ENSDARG00000006301 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 14148113)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 13900678
GRCz11 9 13871881
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAGTTTTCAGATGACGAGCTGGATCATGCTGCGGAGGAGGACAGCGAT[A/T]AAGAGGACCAGGACTTGGACAAAATGTTTGGAGCGTGGCTTGGAGAGCTG
Long Flanking Sequence:
ATATCAGCATAAATAACTTAAAAAAAAATTATATATATATATATATATATATATAAAGGTACAAGCTCAAATTGACCAAGCATATTTTAGGTCTATAAGTGTTCATAAAGGTTTTTAATGTGCATTCAAATGCCTGTTGGTCATGTTTTTATGTTTTACTGGTTCAGTGGTCGTCAGTAAACTAATCTATTTTCACATTCACACCTATTTTAATTTATCTGTCTCCTGACAGATCTTTTTTTTTGTTTGTTTGTTTTTGCATGGATTTTGTTTCTAGCATTATAAAGTCCAAAAGTCATGAAGCCTATTGAAAAAAACTCGATTTGTTGGCATTTTTTTCTATGTTTATAAAATGATCATTAAACCTACACAGTTGTTTTTTCATTAATGATACCTCAGATTGCATTTTAAATGTAAACATCTGTACAATGTTGGTTGTGTTTCAGATGGAGCAGTTTTCAGATGACGAGCTGGATCATGCTGCGGAGGAGGACAGCGAT[A/T]AAGAGGACCAGGACTTGGACAAAATGTTTGGAGCGTGGCTTGGAGAGCTGGACAAACTAACAAAGGTGAGACTAAAAGATGAGGACTGTGAATCTGTGTCCTGTTAATGCGCTGATGCTAATAATGTCATACTGGTCACGGTTGACAGCATAGATCAGGTCTGTGATGTCATTAAGTCTTTGATTGTTAAATCTGACACTCGTTCAATTAATTTGTGGTAGATGCATTTTAATATATTACTCTATCGTGATGCAATAGTTTTAAATGTTATGCAATAAGGTGTATTAGGATTAAATTGCGTCATTGATAATCTGTATTTTTCTGAATTAATCAGATCCTCAAATCCCTGTTTAGTGTTATTACAGGTGAAACTCCTGTATTTTGTTATCTCATCGCTCTGTTGTTTTTAGAGTCTGGATGACGGGAGACCAGAGAAGGTGCAGAAAGCTCCTCTCAGACAAGATTCAAACATGGCCAACATGGCCTACCGCTTCTCCGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8384
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061156 Nonsense 71 1346 2 14
ENSDART00000146597 Nonsense 71 670 2 13

The following transcripts of ENSDARG00000006301 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 14147610)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 13900175
GRCz11 9 13871378
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCAGACAAGATTCAAACATGGCCAACATGGCCTACCGCTTCTCCGTTTA[C/A]AACATCAACGGTGAGGTCACACAGTACAATACAAGATGCTTCATTTATAT
Long Flanking Sequence:
GAGGACCAGGACTTGGACAAAATGTTTGGAGCGTGGCTTGGAGAGCTGGACAAACTAACAAAGGTGAGACTAAAAGATGAGGACTGTGAATCTGTGTCCTGTTAATGCGCTGATGCTAATAATGTCATACTGGTCACGGTTGACAGCATAGATCAGGTCTGTGATGTCATTAAGTCTTTGATTGTTAAATCTGACACTCGTTCAATTAATTTGTGGTAGATGCATTTTAATATATTACTCTATCGTGATGCAATAGTTTTAAATGTTATGCAATAAGGTGTATTAGGATTAAATTGCGTCATTGATAATCTGTATTTTTCTGAATTAATCAGATCCTCAAATCCCTGTTTAGTGTTATTACAGGTGAAACTCCTGTATTTTGTTATCTCATCGCTCTGTTGTTTTTAGAGTCTGGATGACGGGAGACCAGAGAAGGTGCAGAAAGCTCCTCTCAGACAAGATTCAAACATGGCCAACATGGCCTACCGCTTCTCCGTTTA[C/A]AACATCAACGGTGAGGTCACACAGTACAATACAAGATGCTTCATTTATATTTTTGTGTTATTATCATAACATCATTGTCACTATTAAACTAATATTGATGTAATTGGAGGAGGGCTGTTATAAATTTGTTTGTAATAAAAATCACGAAGACCTCAAGTGGGAACTACTGTATATACAGTAAGGCTTTCATTTTAATGCAAAATTTTCAGTGAAATTTTAAGTTTTTTTTATGTTAATAAAAAAGTTTCTAATGCTAAGTATTTTATTTTTAGGTAAAACTGCAACATTTTGAGAGATTGTTACTGTTTAAGACACTGTAACGGTTTTCTATTTTAGTACTTTTTTAATATATAATAGGCAAGGTGGCAATTAATCTGGCCTTCAGTGTGTCACATGATCTGTCATAATCATCTGTTAATACAATCAAAAAAACTTAGTTGTTACATTTTTAAACTACTTAGGTTTTTATAGATTTCAAAAGAAAACAATATCTCTTTGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34583
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061156 Essential Splice Site 562 1346 11 14
ENSDART00000146597 Essential Splice Site 583 670 11 13

The following transcripts of ENSDARG00000006301 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 14098295)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 13850860
GRCz11 9 13822063
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGATGTCAGAATGCTGCATCAGTGGGTCAACGGAATACGCATTGCCAAG[G/A]TTTCAGCTTATAATATGATAACCCTCTTTAAATAATGTGTATTGCTAGTT
Long Flanking Sequence:
TGCACCAACCTGATATTTTGTAAACAAAACCTAGTTAACAAGTGCCCTGATGTTAAAAATTGCATAAAGGCAAATCAGTTAGCTTGACACATTTAACATTCCCTTTTTAGCTAGTGCTTGCCAGTTTTGTGTGTAAAATGTTGTAGACATTTAGAGAATGAACTATGTGTGAGACAAACCTTACAGAAAGCACATGAGGTAATGCAACCCCATGCTAAAATCATGTTGGGAATGGTTTTCTGACCATGCCAAATTTACGTGTTCCATATATTTAAAATGTTGTCTATAAACAAGCTGAGATTACACAAATTAAAAATGGTATAATAAGTCCAAAACCCTAATAACATAAAACTGTTACTTCATGCATCAGTACAGCTAACATCTCTGATTTCCCCACACAGCACCCTCAGATTCAGAAGAAATCACAGTACATCAAGTATCTGTGTTGTGATGATGTCAGAATGCTGCATCAGTGGGTCAACGGAATACGCATTGCCAAG[G/A]TTTCAGCTTATAATATGATAACCCTCTTTAAATAATGTGTATTGCTAGTTTCTGTGCCTAAATATATGCTAAATGTGTTCATTGCAGTATGGGAAGCAGTTGTATGTTAACTACCAGGAAGCTATGAGGCGCACAGAGGCTGCACATGATTGGTCCTCTCTGTCCAGCTCCAGTATTAAGTCTTGTTCCAGTTCCTCAAGTCTACCAGGTGAGTTCAGCAAAGCAGTAGCAAAAATACAGGTCTTGTACATGCAGATGTATGTATTGTTGTCAATGAGACAGGTTAGGGGCTTTCACTCCAGGTAGATATAGGAACTAGCAGTCTAGTTCTCCAAGAACTAAATTTTCCCCTTGGGTCATTGTTGGAATTTAGATGTAAAAGTTATGAGATTAAAAGACCAAAAAGGAAGACCGAGTAAGGCCCAATCCCAGTTCTACAGCTTAAATCTTCCCATTAGCCCTACCCCTCATTTAGCATGTTCCTGTGAAGAGGTAGGGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38727
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061156 Nonsense 830 1346 14 14
ENSDART00000146597 None None 670 None 13

The following transcripts of ENSDARG00000006301 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 14092748)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 13845313
GRCz11 9 13816516
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCTTATCTACACAGTAACGGATATTTGCCTCCACCACCACCCCCAGAA[C/T]AGTTAAAATATCCACCTCCCCTCAGTACCAATGGGCTCCAACAATTCTTA
Long Flanking Sequence:
CTTACCCTCTGCAACTCCCCCCACTGCCCCAGTCTTTGCAGTCTCGAAGCAGCTACAGCGGAGTGTCTCCAGCATCACCTTCCTCACCCCCCTCTCCACCACCACCACCTCCGCCACCTCCTCCACTTCCCAACCCCACACACCACTCCACCCCAGTTGTGTTCACTAAGTACAGCACCCTTGCAAGGCTGCAAAACATCTCCCAGGCTCCGAATCATTACAAACAAACACCATTATTAGCAGCACAGCAACAACCTACGCCCCCTGTGCCACCCCCACAGTGTCTCAAACCTCTTATGAATAACACAACTGAAGTTGCCAGCAGTCCTCCTCCAGCCCCACCACCACCACCTCCTCCAGAAATGCCAGTGCCAGGATCGGCCATGGCAGTGTTAAAGCATGCCCCTATAAGCCCCCAGTACACTCCCCCTCCACCTCCAGAGGAAGACCCATCTTATCTACACAGTAACGGATATTTGCCTCCACCACCACCCCCAGAA[C/T]AGTTAAAATATCCACCTCCCCTCAGTACCAATGGGCTCCAACAATTCTTAGCTCAGAAGTTCCCCAATATGACCTATGACTTCTCACCTGTCCAGCAAGATGAAGAACCTCCACCGCCTCCTCCAGTATGTTTCTCTCCACCGCCTCAGCAGTCAGGCCCACCTGCTCCTCCTAAAACATTTACTGGTGGGTTTCCACCCCAAACAGCTCCAAAGCCAGGCCATGGCATTTCCCCCATTTCCCCTGTGCCACCTTCTCTTTCTCCAACCCCTTCTTTGATGAAGAAACAGCAGAGCCTCTCCAGTGGGCACAGTCCCAATCAACCGCCGCCTACCCTTCCCAAACAATACAGCCTTTCTTCCAAAGCTCCATCTGTATCTGCTCCTATCTCTCCAACCCAGTCACTTGTAAAACAGATTGTTAACCAGTTTCCCGATACCCTTGATGGATCCAAAGGTCCCATATCTCCCCCTGTGGTAAAAAACAAGCCTAAATGGCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34582
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061156 Nonsense 1128 1346 14 14
ENSDART00000146597 None None 670 None 13

The following transcripts of ENSDARG00000006301 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 14091853)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 13844418
GRCz11 9 13815621
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCTCCAAGGAGTCTTCTCGGGCACTAACAAAACCAGGCAAGATCAACT[T/G]AGCTAATCTGCCCTTGGCTCTACAGGGGAGGCAAAGTCACTGTCGTCAAT
Long Flanking Sequence:
AACCCAGTCACTTGTAAAACAGATTGTTAACCAGTTTCCCGATACCCTTGATGGATCCAAAGGTCCCATATCTCCCCCTGTGGTAAAAAACAAGCCTAAATGGCAACCAGGAGGACAGGCACAACCACAGTCTCCTGAATTTCCTCCACCTCCTCCAGAAAGTACCCTTGAATTTCCTCCTCCTCCTGCTCCAAGTCCTCCTCCTGCTTCACAGCCCTCTGGTAAATCTGGATCACCAATCAAAAAATCCCCATCAACATCGTCAAATTCTTCTACTGGTTCAGGAGGAAAGAAGCCCCCTCCAACGCCACAGCGCAATTCTAGCATGAAGGCCACTTCTTCTGTTGAGTACCAGGAGTCTAAGAAAGTGGAGGATCTGGTCAGCATGTTTGGTCAAACAAGTCAAGCCCCACCCAGCTCCTTCTCAACTCCATCCTCTACAACAGGATCACCCTCCAAGGAGTCTTCTCGGGCACTAACAAAACCAGGCAAGATCAACT[T/G]AGCTAATCTGCCCTTGGCTCTACAGGGGAGGCAAAGTCACTGTCGTCAATCCAGCGCAGACTTTCCATCTCCTCCTCTGGATTGTGAGTTTCCCCCTCCACCGCCAGACTCCGAACTCCTGCCTCCACCACCTCTTCCATCAGAACTGCACATTGGGGCTCCCAAAGTGGCTGTGGTGAACCCACAACCCCAGCATTCCTCCAGCTCCACATCCTCATGGAAGCAGAGCTCCTTGAAGAAAATGCCCCCTCCTACTATGCATCGCCGCAGCAGTGGCCCACCTGAGCAGCTAGCTCTTTCTCCACCTCCTCAGCAGATGCCTCTGTCCTCTTTTAACTCTCAGATCCCACCTACGTCTCCCAAGGCAAATCTTTCCATGCAACCCAACTTCCTGGAAGACCTCAACAGAACTCTCAAAAGAAAGTCCATGACTCGACATGGCTCCCTCACCTCCTCCCGAATCTCAGCCAAGCTGGAGCCTGTAGCCACAATGGACGATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38726
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000061156 Nonsense 1190 1346 14 14
ENSDART00000146597 None None 670 None 13

The following transcripts of ENSDARG00000006301 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 14091668)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 13844233
GRCz11 9 13815436
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCATCAGAACTGCACATTGGGGCTCCCAAAGTGGCTGTGGTGAACCCA[C/T]AACCCCAGCATTCCTCCAGCTCCACATCCTCATGGAAGCAGAGCTCCTTG
Long Flanking Sequence:
CTGCTCCAAGTCCTCCTCCTGCTTCACAGCCCTCTGGTAAATCTGGATCACCAATCAAAAAATCCCCATCAACATCGTCAAATTCTTCTACTGGTTCAGGAGGAAAGAAGCCCCCTCCAACGCCACAGCGCAATTCTAGCATGAAGGCCACTTCTTCTGTTGAGTACCAGGAGTCTAAGAAAGTGGAGGATCTGGTCAGCATGTTTGGTCAAACAAGTCAAGCCCCACCCAGCTCCTTCTCAACTCCATCCTCTACAACAGGATCACCCTCCAAGGAGTCTTCTCGGGCACTAACAAAACCAGGCAAGATCAACTTAGCTAATCTGCCCTTGGCTCTACAGGGGAGGCAAAGTCACTGTCGTCAATCCAGCGCAGACTTTCCATCTCCTCCTCTGGATTGTGAGTTTCCCCCTCCACCGCCAGACTCCGAACTCCTGCCTCCACCACCTCTTCCATCAGAACTGCACATTGGGGCTCCCAAAGTGGCTGTGGTGAACCCA[C/T]AACCCCAGCATTCCTCCAGCTCCACATCCTCATGGAAGCAGAGCTCCTTGAAGAAAATGCCCCCTCCTACTATGCATCGCCGCAGCAGTGGCCCACCTGAGCAGCTAGCTCTTTCTCCACCTCCTCAGCAGATGCCTCTGTCCTCTTTTAACTCTCAGATCCCACCTACGTCTCCCAAGGCAAATCTTTCCATGCAACCCAACTTCCTGGAAGACCTCAACAGAACTCTCAAAAGAAAGTCCATGACTCGACATGGCTCCCTCACCTCCTCCCGAATCTCAGCCAAGCTGGAGCCTGTAGCCACAATGGACGATATGGCCCTTCCACCCCCTCCTCCAGAGCTGCTGCTGGGCCAGCAGAAAAAGGGTGGATACACGAGCGCCAACATCTCAGGCTATGCAACATTACGGCGGGGTCCCCCACCTGCTCCACCCAAACGGGACCAAAACACTAAACTGACAAGCGAGTGGTAGTTGGACATGTGCCGAGTATGACTATGT
Associated Phenotype:
Not determined