Busch Lab

ZMP

zgc:194119

Ensembl ID:
ENSDARG00000070940
ZFIN ID:
ZDB-GENE-081022-57
Description:
5-hydroxytryptamine receptor 2B [Source:RefSeq peptide;Acc:NP_001038208]
Human Orthologue:
HTR2B
Human Description:
5-hydroxytryptamine (serotonin) receptor 2B [Source:HGNC Symbol;Acc:5294]
Mouse Orthologue:
Htr2b
Mouse Description:
5-hydroxytryptamine (serotonin) receptor 2B Gene [Source:MGI Symbol;Acc:MGI:109323]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa16649 Nonsense Available for shipment Available now
sa32414 Nonsense Available for shipment Available now
sa3157 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa16649
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104569 Nonsense 233 443 3 3
Genomic Location (Zv9):
Chromosome 22 (position 40657209)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 37737124
GRCz11 22 37672132
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCGAGAGCTGCGAGGCCCTCCATTTCCACGGTCTTCCAGCAGGAACTCT[C/A]AGTTCTTGCTTCACCAGAGAAAATGGTCATATCGAATGGAATAAAAAGAG
Long Flanking Sequence:
CAGTAATTACAGTCCTTTGCTGTTCGTTTGGTGTGTTCAAAGGTTTTGGACCGGATGCGGCTGACAAGTTCAAGTTCTTAGGAGTCAGCTTTGCGTGTCCCAGATTTTAGCTAAACACTGTAGGACAGTGAATCTCCAAGAAAAAGACTCAACACTTCCAACTTAGTCAATGAATGTCAATGTTTTATTTAAGTCCTGTTCTCTGCTCAATTTAACGATTGGTCTTTCTCCAACAGGCATTGCGATACCGATTCCAATCAAAGGGCTTCAATTCTTTGATCATCCGAACATCACCTTCAACAAAAACCACACCTGCTTGTTGTCGCCGGAGGGCTTCAGGGACTTCAAGGTGTACGGGTCTTTGGTGGCTTTCTTCATACCCCTCGCAATCATGATGATCATTTACTTGCTGACAATCCAAGTACTGCGGAAAAAGGCCTATCTTTTAAGATCGAGAGCTGCGAGGCCCTCCATTTCCACGGTCTTCCAGCAGGAACTCT[C/A]AGTTCTTGCTTCACCAGAGAAAATGGTCATATCGAATGGAATAAAAAGAGACCGAACACTGAACCCCGTCAATCCCATCACAGGAGATGAGGTCCCTCTGCGCAGGATGTCCACCATAGGAAAGAGGTCCATGCAAAACTTGACCAATGAACAAAGGGCCTCGAAGGTTCTGGGGATCGTATTCATGCTGTTCGTTGTGATGTGGTGTCCTTTCTTCATTACTAACGTGACTTCTGTGCTCTGTGAAAGGTGCAACGGTAATCTAGTGGACCAGCTGCTGGATATCTTTCAGTGGGTGGGCTATGTTTCGTCAGGCATCAACCCGCTGGTCTATACTCTGTTCAATAGGACGTTCAGACTGGCCTTCAGGCGCTACATCACCTGTAACTACAAGAGCGTGAGGACTCCGAAACTGCAACGGAGAAGCAAAATCTCCTTTCGTTCATCAGTGACCGAAAACTCAAAGCGGTTTATGAAACACGGTATGAAGAATGGCATCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32414
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104569 Nonsense 344 443 3 3
Genomic Location (Zv9):
Chromosome 22 (position 40656875)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 37736790
GRCz11 22 37671798
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTTTCAGTGGGTGGGCTATGTTTCGTCAGGCATCAACCCGCTGGTCTA[T/A]ACTCTGTTCAATAGGACGTTCAGACTGGCCTTCAGGCGCTACATCACCTG
Long Flanking Sequence:
TTCAGGGACTTCAAGGTGTACGGGTCTTTGGTGGCTTTCTTCATACCCCTCGCAATCATGATGATCATTTACTTGCTGACAATCCAAGTACTGCGGAAAAAGGCCTATCTTTTAAGATCGAGAGCTGCGAGGCCCTCCATTTCCACGGTCTTCCAGCAGGAACTCTCAGTTCTTGCTTCACCAGAGAAAATGGTCATATCGAATGGAATAAAAAGAGACCGAACACTGAACCCCGTCAATCCCATCACAGGAGATGAGGTCCCTCTGCGCAGGATGTCCACCATAGGAAAGAGGTCCATGCAAAACTTGACCAATGAACAAAGGGCCTCGAAGGTTCTGGGGATCGTATTCATGCTGTTCGTTGTGATGTGGTGTCCTTTCTTCATTACTAACGTGACTTCTGTGCTCTGTGAAAGGTGCAACGGTAATCTAGTGGACCAGCTGCTGGATATCTTTCAGTGGGTGGGCTATGTTTCGTCAGGCATCAACCCGCTGGTCTA[T/A]ACTCTGTTCAATAGGACGTTCAGACTGGCCTTCAGGCGCTACATCACCTGTAACTACAAGAGCGTGAGGACTCCGAAACTGCAACGGAGAAGCAAAATCTCCTTTCGTTCATCAGTGACCGAAAACTCAAAGCGGTTTATGAAACACGGTATGAAGAATGGCATCAGCCCTGTAGGTTATCAGAGTCCGATCAGGCATCGATCAACGCAGCTGCAGACGTCTGCAAATATCATGTTAGACACGTTGCTGTTGACAGACAATGAAGACTGCAAACCTGATGAACACGTAAGCCACGTGTAGAAGATCTCATGAAAAGCCAAGAAAGAGATGTGCGATAGTCTTTTAGTGGCCACAAAGCTCATGTGAGGCAATGAAATATGGCAACACTAGGATATTGCACCCAATGTATGAACGTTTCCATAGTTCCTATAACTATTGGTGGAAGTGCACTTTTTTTGGCACGTTTGTGCATTACAGGAACTGAGAATATTTTTAGCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3157
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104569 Nonsense 438 443 3 3
Genomic Location (Zv9):
Chromosome 22 (position 40656595)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 37736510
GRCz11 22 37671518
KASP Assay ID:
554-2585.1 (used for ordering genotyping assays)
KASP Sequence:
TCATGTTAGACACGTTGCTGTTGACAGACAATGAAGACTGCAAACCTGAT[G/T]AACACGTAAGCCACGTGTAGAAGATCTCATGAAAAGCCAAGAAAGAGATG
Long Flanking Sequence:
CCATAGGAAAGAGGTCCATGCAAAACTTGACCAATGAACAAAGGGCCTCGAAGGTTCTGGGGATCGTATTCATGCTGTTCGTTGTGATGTGGTGTCCTTTCTTCATTACTAACGTGACTTCTGTGCTCTGTGAAAGGTGCAACGGTAATCTAGTGGACCAGCTGCTGGATATCTTTCAGTGGGTGGGCTATGTTTCGTCAGGCATCAACCCGCTGGTCTATACTCTGTTCAATAGGACGTTCAGACTGGCCTTCAGGCGCTACATCACCTGTAACTACAAGAGCGTGAGGACTCCGAAACTGCAACGGAGAAGCAAAATCTCCTTTCGTTCATCAGTGACCGAAAACTCAAAGCGGTTTATGAAACACGGTATGAAGAATGGCATCAGCCCTGTAGGTTATCAGAGTCCGATCAGGCATCGATCAACGCAGCTGCAGACGTCTGCAAATATCATGTTAGACACGTTGCTGTTGACAGACAATGAAGACTGCAAACCTGAT[G/T]AACACGTAAGCCACGTGTAGAAGATCTCATGAAAAGCCAAGAAAGAGATGTGCGATAGTCTTTTAGTGGCCACAAAGCTCATGTGAGGCAATGAAATATGGCAACACTAGGATATTGCACCCAATGTATGAACGTTTCCATAGTTCCTATAACTATTGGTGGAAGTGCACTTTTTTTGGCACGTTTGTGCATTACAGGAACTGAGAATATTTTTAGCTTTTAGTACCATTAAACACCATTTGGTGAACTAATTTCAAACTAGAATCTATCCTCCGGGTTCCTACAGGTGGTGTGAGTGCAACCAGAAACATGCCTTAAAGGGGAAGTTGAAAGGAATTTTGTTGTCTGGTGGCTAGTTCCTGTAACTGTTACCCATTCCAAAATAAAAATTTAACAGGACCATATATAAAGGTCAGAGGTTTGTTATCCATTGTAGCAGTTTAAAAACTGTTTATATGACAACTATGTAGCCAAAAATGTCAACATTTTTCTCACTTTTA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461