ZMP
furina
Ensembl ID:
ZFIN IDs:
Description:
furin A [Source:RefSeq peptide;Acc:NP_001038571]
Human Orthologue:
FURIN
Human Description:
furin (paired basic amino acid cleaving enzyme) [Source:HGNC Symbol;Acc:8568]
Mouse Orthologue:
Furin
Mouse Description:
furin (paired basic amino acid cleaving enzyme) Gene [Source:MGI Symbol;Acc:MGI:97513]
Alleles
There are 3 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa40848 | Nonsense | Mutation detected in F1 DNA | Not yet available |
sa9922 | Nonsense | Available for shipment | Available now |
sa31552 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa40848
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000091468 | Nonsense | 348 | 713 | 12 | 16 |
ENSDART00000091470 | Nonsense | 441 | 806 | 11 | 15 |
Genomic Location (Zv9):
Chromosome 7 (position 15057942)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 7 | 13935248 |
GRCz11 | 7 | 14180711 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGATATGGTCTGCTGGACGCTGGGGCCATTGTAGCCTTAGCAAAGAACTG[G/A]ACAAATGTGGGACCTCAGCATAAATGTGTCCTTTCCCTGGTGTCTGAGCC
Long Flanking Sequence:
CGTGAAGCATGCGAGCGGTTTTTGTGTTTTGTTCCTCACATTTGAAGGCCACTGACGCTTTTTTTTCTTTCCTCCATAGTAAAAATCTAACCTGGAGGGACATGCAGCATCTGGTTGTGAGGACGTCCAACCCTGCCCACCTCACCACCAATGACTGGAAGATAAATGGAGTGGGTCGGCGAGGTAAAAACCCATCTCGATCATTTCACAGCTCCATTCTTTTTTTTCCCTCCGTCTGCTTTTTCTTTCCACTTCTCAGATACTTGAACGTTTTGTGGCGCGATCGATAGTGTTATCGTTGGACGCACCAATCAGCAAACGGCTCCGGATCTCTTAAAGATCTCAACCTCATTAATTCAGCTCTTATTATGTCAGTCTTTTAAAAGTGCCTCTATTGTTACTTTCAACAGTATTGATTTTTTTTTTTCTCCTACAGTAAGCCATTCTTATGGATATGGTCTGCTGGACGCTGGGGCCATTGTAGCCTTAGCAAAGAACTG[G/A]ACAAATGTGGGACCTCAGCATAAATGTGTCCTTTCCCTGGTGTCTGAGCCCAGGTAGGTTAAAACACTCCTTAGTTGATGAGTCTTTTAAAGGGATTAGTTCAACTACATGTCATTTTATGCGTCCATGTTAGACTGAATGTCAATTCTGTGGCTTTCTATATAATGAATCCTTTTCGTGAGCAGAGACTGCCAATGTTAATACACAAAGATGTAAACATATAAACTCCATTATTAAAGATGGCCACTTTATTAGGTACACCTGTCCAACTGCACAAATTTCTAATCAGCCAATCACATGGCAGCAACTCAATGCATTTAGGCATGTAGACATGGTCAAGACGATCCGCTGCAGTTCAAACCGAGCATCAGAATAGGGAAAAAGGGTGACTTTAAACGTGACAGTGGGCTGGTCTGAGTATTTCAGTAACTGCTGATCTACTATGATTTTCAAGCACAATCATCTCTAGGGTTTACAGAGAATGGTCCGAAAAAGAGAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa9922
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000091468 | Nonsense | 411 | 713 | 13 | 16 |
ENSDART00000091470 | Nonsense | 504 | 806 | 12 | 15 |
Genomic Location (Zv9):
Chromosome 7 (position 15063550)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 7 | 13940856 |
GRCz11 | 7 | 14186319 |
KASP Assay ID:
2259-8523.1 (used for ordering genotyping assays)
KASP Sequence:
CAAGCGCAGCTGACMCTGTCCTACAACCGCAGAGGAAACCTGGCYATCTA[T/A]CWGATCAGCCCACAGGGGACCCGCTCCACACTGCTTCCTCCCAGGTWAAA
Long Flanking Sequence:
GATTTTAGGCCAAATCGCCTATCCCTAAACTCAGAAAACTTAAGGTTATTACTTACTATAATCTTTATTAGTTGCTAATAACTTTAACTAATTAACCAGTTACTAATAGCTTTTAACACCTAAAGTTTTATTTATATATATATATATATATATATATATATATATATATATATATATATATATACGTATAAACATAGTTAACCTGCAGTTATATAGTATATAGGTAATGTCTATGTGTGCATGTTCAGTGTACGTTTAAGTGTATGTGTATATGCATAATCTATGTTTGTAGAAGCATAAGGTTCATTGTGTTTAGCTGTCAGTTCTTAACACTTTTCTTTTATCATTCTATTTGTCTGTTTTAGGAATATCGGGAGTTATTTGGTCATCAACAAGACTGTGGATGCGTGTACTGGGATGGCCAACTTTGTGAGCTCATTAGAGCATGTTCAAGCGCAGCTGACACTGTCCTACAACCGCAGAGGAAACCTGGCCATCTA[T/A]CTGATCAGCCCACAGGGGACCCGCTCCACACTGCTTCCTCCCAGGTTAAAATCCTAGAGAGCTACAGTCACACTCATGATATTCAACTCAATTCAATTCAAGTTAATTTGTGTAGAGCTTTTCACAATAGTTATTGGCCTAGAGCAGCTTTATAAAAGGTGTCTGGTATTACATCAATCAAACAATCAAACAGAAAAAAGTTTAGGTCTAAGTAGAGTGCAAATACATAGTTAATCAACAATTATACAATATAATGTACTGTAATGTGAAATGTTCAAAAAGGGATCTGTATTCTGTTCTATTTACTGAACTGTGTAGTGTTGGGTGTAATTACTTACAAAGTAACTAATTACTGTAATTAAATAACCTTTCTGCTTAAAGTAAACCAAGAAATTACCTTTAATTTGAGGTAATTTAATTACAGTTCCTCATAATGTACTTGACTTAAATACTGTACATAAATGTAACTGTAAAGTCTGTGAAGCCGAGTAATATATACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa31552
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000091468 | Essential Splice Site | 426 | 713 | 13 | 16 |
ENSDART00000091470 | Essential Splice Site | 519 | 806 | 12 | 15 |
Genomic Location (Zv9):
Chromosome 7 (position 15063596)
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTATCTGATCAGCCCACAGGGGACCCGCTCCACACTGCTTCCTCCCAGG[T/C]TAAAATCCTAGAGAGCTACAGTCACACTCATGATATTCAACTCAATTCAA
Long Flanking Sequence:
TATTACTTACTATAATCTTTATTAGTTGCTAATAACTTTAACTAATTAACCAGTTACTAATAGCTTTTAACACCTAAAGTTTTATTTATATATATATATATATATATATATATATATATATATATATATATATATATACGTATAAACATAGTTAACCTGCAGTTATATAGTATATAGGTAATGTCTATGTGTGCATGTTCAGTGTACGTTTAAGTGTATGTGTATATGCATAATCTATGTTTGTAGAAGCATAAGGTTCATTGTGTTTAGCTGTCAGTTCTTAACACTTTTCTTTTATCATTCTATTTGTCTGTTTTAGGAATATCGGGAGTTATTTGGTCATCAACAAGACTGTGGATGCGTGTACTGGGATGGCCAACTTTGTGAGCTCATTAGAGCATGTTCAAGCGCAGCTGACACTGTCCTACAACCGCAGAGGAAACCTGGCCATCTATCTGATCAGCCCACAGGGGACCCGCTCCACACTGCTTCCTCCCAGG[T/C]TAAAATCCTAGAGAGCTACAGTCACACTCATGATATTCAACTCAATTCAATTCAAGTTAATTTGTGTAGAGCTTTTCACAATAGTTATTGGCCTAGAGCAGCTTTATAAAAGGTGTCTGGTATTACATCAATCAAACAATCAAACAGAAAAAAGTTTAGGTCTAAGTAGAGTGCAAATACATAGTTAATCAACAATTATACAATATAATGTACTGTAATGTGAAATGTTCAAAAAGGGATCTGTATTCTGTTCTATTTACTGAACTGTGTAGTGTTGGGTGTAATTACTTACAAAGTAACTAATTACTGTAATTAAATAACCTTTCTGCTTAAAGTAAACCAAGAAATTACCTTTAATTTGAGGTAATTTAATTACAGTTCCTCATAATGTACTTGACTTAAATACTGTACATAAATGTAACTGTAAAGTCTGTGAAGCCGAGTAATATATACACTCACAAGCACTTTATTAGGTACACCTGTCTAACTGCTCGTTAACA
Associated Phenotype:
Not determined