Busch Lab

ZMP

si:ch211-158m24.10

Ensembl ID:
ENSDARG00000090103
ZFIN ID:
ZDB-GENE-070705-71
Description:
Novel myosin family protein [Source:UniProtKB/TrEMBL;Acc:B8A559]
Human Orthologues:
MYH6, MYH7
Human Descriptions:
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Mouse Orthologues:
Myh6, Myh7
Mouse Descriptions:
myosin, heavy polypeptide 6, cardiac muscle, alpha Gene [Source:MGI Symbol;Acc:MGI:97255]
myosin, heavy polypeptide 7, cardiac muscle, beta Gene [Source:MGI Symbol;Acc:MGI:2155600]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa7568 Missense Mutation detected in F1 DNA Not yet available
sa30619 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa12688 Nonsense Available for shipment Available now
sa14985 Nonsense Available for shipment Available now
sa31459 Nonsense Available for shipment Available now
sa6987 Nonsense Mutation detected in F1 DNA Not yet available
sa20462 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa7568
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 None None 232 None 7
ENSDART00000139917 Missense 66 1222 3 23

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 33889011)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31651243
GRCz11 5 32251396
KASP Assay ID:
554-4016.1 (used for ordering genotyping assays)
KASP Sequence:
GAATTCAGGTGTTCTTCAAAGCTGGTCTKCTGGGTACTCTTGAGGAGATG[C/A]GTGATGAGAAACTGGCTAGTCTGGTCACAATGACYCAGGCTCTCTGCCGT
Long Flanking Sequence:
GACGGTGTTGATAACATCATGCTGTTACTTATAGGTCTTATGGAGAACTTCCTAGTTATCCACCAGCTGAGGTGTAACGGTGTACTGGAGGGTATCAGAATCTGTAGAAAGGGTTTCCCAAGCAGAATTCTTTATGCCGACTTCAAGCAGAGGTAAATGGGACCTTCTGAAAGCATAATTAACTTTAGGAATTACTTAATTACAAGATCTTAACAATTTTCATAAATGTTCAACAGATACAAGGTGTTGAATGCCAGTGTTATCCCAGAGGGACAGTTCATTGACAACAAGAAGGCCAGTGAGAAACTCCTGGGATCTATTGATGTTAATCATGATGAGTACAGATTTGGACACACAAAGGTTCATATTTTAATTTACAGTTTTAAGAGATTCAGTGATCAGTGTAGTTTACATTAGGCATCAATTTCTTTTCCTTTTCTCTATTTACATGAATTCAGGTGTTCTTCAAAGCTGGTCTGCTGGGTACTCTTGAGGAGATG[C/A]GTGATGAGAAACTGGCTAGTCTGGTCACAATGACTCAGGCTCTCTGCCGTGCTTATCTGATGAGGAGAGAGTTTGTGAAGATGATGGAGAGGAGGTGAGGGAAAGCATGAGTTATAATTGTGTGAATGGTAAAAAGTAATAATTATGGCATTTAATGATGAACTATTCACAGGGAGTCCATTTACACCATCCAGTACAACATCCGCTCATTCATGAATGTCAAACACTGGCCATGGATGAAGGTTTACTACAAGATTAAGCCTCTGCTGAAGAGTGCTGAGACTGAGAAAGAACTGGCAAACATGAAAGAGGACTTTGTCAAATGCAAAGAAGATCTTGTCAAGGCTGAAGCTAAAAAGAAGGAGCTGGAAGAGAAGATGGTGGCACTGCTGCAAGAGAAAAATGATCTGCAGCTGGCAGTGGCTTCTGTGAGTATTCTTAATTTAATAAACTCAATCTCATCTCCATTAAAATTAGTTTGCAATGATATAACAATGTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30619
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 None None 232 None 7
ENSDART00000139917 Essential Splice Site 264 1222 None 23

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 33889845)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31652077
GRCz11 5 32252230
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATACAGTATATATTGTAAAATAACTAAGCGTATTTGAAATCAAATCACAC[A/T]GGTTAAGAACTTGACAGAGGAAATGGCATCTCAGGATGAGAGCATTGCCA
Long Flanking Sequence:
ATCTTGTCAAGGCTGAAGCTAAAAAGAAGGAGCTGGAAGAGAAGATGGTGGCACTGCTGCAAGAGAAAAATGATCTGCAGCTGGCAGTGGCTTCTGTGAGTATTCTTAATTTAATAAACTCAATCTCATCTCCATTAAAATTAGTTTGCAATGATATAACAATGTGTTTTCCTAACAGGAAGCTGAAAATCTCTCAGATGCTGAGGAGAGGTGTGAGGGTCTGATCAAGAGCAAAATCCAGCTTGAGGCTAAACTCAAAGAGACAACTGAGAGACTGGAGGATGAGGAAGAAATCAATGCTGAACTGACAGCCAAGAAGAGAAAACTGGAGGACGAGTGCTCTGAGCTGAAGAAAGACATTGATGACCTGGAGCTCACCTTGGCTAAAGTGGAAAAGGAGAAACATGCCACTGAGAATAAGGTTGGAGACAAAGGCTCTTTGACTTATATATACAGTATATATTGTAAAATAACTAAGCGTATTTGAAATCAAATCACAC[A/T]GGTTAAGAACTTGACAGAGGAAATGGCATCTCAGGATGAGAGCATTGCCAAGCTTACAAAGGAGAAGAAAGCCCTCCAAGAGGCACATCAGCAGACTCTGGATGATCTTCAGGCTGAGGAGGACAAAGTCAACACCCTGACCAAATCCAAGACAAAGCTTGAGCAGCAAGTTGATGATGTGAGCTCTATGTTAAATATGTCTAGAATTGATTTATAATTTTTGCTTTTGAATATATTGAATTAAATATGTTATAAACATCATTGTCATATAGCTTGAGGGTTCCCTTGAACAAGAAAAGAAGCTCCGTATGGACCTGGAGAGAGCTAAGAGAAAGCTTGAAGGAGATCTAAAATTGGCCCAAGAGTCTATCATGGACCTGGAAAATGACAAGCAGCAGTCTGAAGAGAAAATTAAAAAGTAAAAAATATATAAATACTTTAACAAAACATTCCACAAACTTGCTGTGTACAAACTATTGATACTTGATCACCCACAGGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12688
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 None None 232 None 7
ENSDART00000139917 Nonsense 664 1222 12 23
Genomic Location (Zv9):
Chromosome 5 (position 33892127)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31654359
GRCz11 5 32254512
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGGGGAATGTCAAAGGCAAACAGTGAGGTTGCTCAGTGGAGAACCAAATA[T/A]GAAACTGMTGCCATCCAGCGCACWGAAGARCTTGAAGAATCCAAGTATGA
Long Flanking Sequence:
AAACTGATAAAATCTTACTTCCAAAGAATGTTTGTTACAACTTACAAAAACAAATTATTTTTTAATCAAAAATATAACCTAAAAAATATCTGAAAAGGTGAGTTTGGCCGTCAGCTGGAGGAGAAAGAAGCTCTGGTTTCTCAGCTCACAAGAGGAAAACAGGCTTTCACTCAGCAAATTGAGGAGCTTAAGAGGCAGATTGAAGAGGAGGTCAAGGTAATAATAATAATAATAATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACCACATTTACTATAGAGTCGGGTTAATAGTATCTGACTTGTTTCCTAGGCTAAGAACGCACTGGCCCATGCTGTACAATCAGCCCGTCATGACTGCGACCTGCTTCGTGAGCAGTTTGAGGAGGAGCAGGAAGCAAAGGCTGAGCTGCAGCGGGGAATGTCAAAGGCAAACAGTGAGGTTGCTCAGTGGAGAACCAAATA[T/A]GAAACTGATGCCATCCAGCGCACAGAAGAACTTGAAGAATCCAAGTATGAACTTTAAAAGAACTGTGTGGTTTTACTTTGGGTGACTGCATGCATTTTTATTGATGACGATGAAATATTTAACAGGAAGAAACTGGCTCAGCGTCTGCAAGAGGCAGAGGAACAAATTGAGGCAGTGAACTCCAAATGTGCATCTCTGGAGAAGACCAAACAGAGACTCCAGGGTGAAGTGGAGGACCTCATGATTGATGTGGAGAGAGCCAATTCTTTGGCTGCCAACCTTGACAAAAAGCAGAGAAACTTTGACAAGGTAAAATATGTAGTCATGTTGTGATGTGATGTTCTTTTTCAGAAAGTAGTATGAGCTTTATTCTAGAGAATACACGTTGAACAAACCTCATAGTGATATATTCCACCCTAAAGGTCCTGGCAGAATGGAAACAGAAATATGAGGAAGGTCAGGCAGAGCTGGAAGGTGCCCAGAAAGAAGCTCGTTCACTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14985
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 None None 232 None 7
ENSDART00000139917 Nonsense 736 1222 13 23
Genomic Location (Zv9):
Chromosome 5 (position 33892422)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31654654
GRCz11 5 32254807
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGATGTGGAGAGAGCCAATTCTTTGGCTGCCAACCTTGACAAAAAGCAG[A/T]GRAACTTTGACAAGGTAAAATATGTAGTCATGTTGTGATGTGATGTTCNT
Long Flanking Sequence:
ATATACCACATTTACTATAGAGTCGGGTTAATAGTATCTGACTTGTTTCCTAGGCTAAGAACGCACTGGCCCATGCTGTACAATCAGCCCGTCATGACTGCGACCTGCTTCGTGAGCAGTTTGAGGAGGAGCAGGAAGCAAAGGCTGAGCTGCAGCGGGGAATGTCAAAGGCAAACAGTGAGGTTGCTCAGTGGAGAACCAAATATGAAACTGATGCCATCCAGCGCACAGAAGAACTTGAAGAATCCAAGTATGAACTTTAAAAGAACTGTGTGGTTTTACTTTGGGTGACTGCATGCATTTTTATTGATGACGATGAAATATTTAACAGGAAGAAACTGGCTCAGCGTCTGCAAGAGGCAGAGGAACAAATTGAGGCAGTGAACTCCAAATGTGCATCTCTGGAGAAGACCAAACAGAGACTCCAGGGTGAAGTGGAGGACCTCATGATTGATGTGGAGAGAGCCAATTCTTTGGCTGCCAACCTTGACAAAAAGCAG[A/T]GAAACTTTGACAAGGTAAAATATGTAGTCATGTTGTGATGTGATGTTCTTTTTCAGAAAGTAGTATGAGCTTTATTCTAGAGAATACACGTTGAACAAACCTCATAGTGATATATTCCACCCTAAAGGTCCTGGCAGAATGGAAACAGAAATATGAGGAAGGTCAGGCAGAGCTGGAAGGTGCCCAGAAAGAAGCTCGTTCACTCAGCACTGAGCTGTTCAAGATGAAGAACTCCTATGAGGAGACTCTGGATCAGCTGGAGACCCTCAAGAGAGAGAACAAGAATCTGCAGCGTAAGAATCAAACATTAAGAATAAAAATATGTGATGAATGAATGTTCTTTATGATACAGAGGATGATTTTTCTTTTTACAGAGGAGATTTCAGATCTGACAGAGCAGATAGGTGAGACTGGTAAGAGCATCCATGAGCTGGAAAAGGCCAAGAAGACAGTGGAGACTGAGAAGGCAGAGATTCAGACCGCCCTAGAAGAGGCTGAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31459
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 None None 232 None 7
ENSDART00000139917 Nonsense 983 1222 17 23
Genomic Location (Zv9):
Chromosome 5 (position 33893585)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31655817
GRCz11 5 32255970
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAACACTCTGATGCAGTCTGAGATCGAAGAGCTGAGAGCTGCTCTGGAG[C/T]AGACAGAGAGAGGACGCAAAGTGGCTGAACAAGAGCTGGTGGATGCCAGT
Long Flanking Sequence:
CCAGGTCAAGGGTGAGATTGACAGGAAGCTTGCAGAGAAGGATGAGGAGATAGAGCAGATCAAGAGGAACAGTCAGAGAGTTACTGAAGCCATGCAGAGCACTCTGGACTCTGAAGTCAGAAGCAGGAATGATGCTCTCAGAATCAAGAAGAAGATGGAGGGAGACCTTAATGAAATGGAGATTCAGCTGAGCCATGCCAACCGCCAGGCTGCTGAGGCCCAGAAACAGCTCAGGAATGTTCAGTCACAACTCAAGGTATGACTTTGTTGTGTCATTGGGGCACATATATGTGTTTGTTTAAGCTAAACTATGTTAAGTAAAAGTCAACTGAAACCAGATAAAAATTTGCTTACAAAGATGTTGTTGTGTTCAGGATGCCCAGCTGCACCTTGATGATGCTGTGAGAGCACAGGAAGACATGAAGGAGCAGGTGGCCATGGTGGAGCGCAGAAACACTCTGATGCAGTCTGAGATCGAAGAGCTGAGAGCTGCTCTGGAG[C/T]AGACAGAGAGAGGACGCAAAGTGGCTGAACAAGAGCTGGTGGATGCCAGTGAGCGTGTTGGACTTTTGCACTCTCAGGTAAAAGAACAATGTTTATGTTTTTGGACATTAAGATAACTGAAAGCATTTTTCAAGACTTTTATTGTTGCTTTACATGTTGTAGAACACAAGTCTTCTGAACACGAAGAAGAAGCTTGAGTCTGACCTTGTTCAGATCCAAAGTGAAGTTGAAGACACTGTACAGGAAGCCAGAAATGCTGAGGAGAAGGCCAAGAAGGCCATCACTGATGTGAGCAACAAAACATAGCAAATATACCACAAAGAACGGATAAACTTAAAAATGTGAAACAAATGCATTTCTGTATGTTTGCAAAAGGCTGCAATGATGGCAGAGGAGCTGAAGAAGGAGCAGGACACCAGTGCTCACCTTGAGAGGATGAAGAAGAATCTGGAGATCACAGTGAAAGACCTGCAGCACCGTCTGGATGAAGCTGAGAATCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6987
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 Nonsense 143 232 4 7
ENSDART00000139917 Nonsense 1132 1222 20 23
Genomic Location (Zv9):
Chromosome 5 (position 33894332)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31656564
GRCz11 5 32256717
KASP Assay ID:
554-4468.1 (used for ordering genotyping assays)
KASP Sequence:
GATGCAGAGCAGAGACGTGGAGCTGATGCTGTTAAAGGCGTCCGCAAATA[T/A]GAGAGGAGAGTCAAGGAGCTCACCTACCAGGTAAAGACATCAGAGCACAA
Long Flanking Sequence:
GCCAGAAATGCTGAGGAGAAGGCCAAGAAGGCCATCACTGATGTGAGCAACAAAACATAGCAAATATACCACAAAGAACGGATAAACTTAAAAATGTGAAACAAATGCATTTCTGTATGTTTGCAAAAGGCTGCAATGATGGCAGAGGAGCTGAAGAAGGAGCAGGACACCAGTGCTCACCTTGAGAGGATGAAGAAGAATCTGGAGATCACAGTGAAAGACCTGCAGCACCGTCTGGATGAAGCTGAGAATCTGGCCATGAAGGGAGGAAAGAAACAACTCCAGAAACTGGAGTCCAGAGTAAGCAGGATTTGTTTCCCGTGTTAATCATTAATATCTAAATAGTATGTCAAGTTGAACACCTTTTTTGAGAAAATTCAGGAAAGCAACATATTTGGGTAAGGTTCAGCAAAGTATCTCCATTAGGTTCGTGAGCTTGAGAGCGAAATCGATGCAGAGCAGAGACGTGGAGCTGATGCTGTTAAAGGCGTCCGCAAATA[T/A]GAGAGGAGAGTCAAGGAGCTCACCTACCAGGTAAAGACATCAGAGCACAAATTTTTATCAAATGAATATAAAATAATTTATGTTCGCTTTATGCAGACTGAGGAGGACAAGAAGAACATCAACAGGCTGCAGGATCTGGTTGATAAGCTTCAGCTGAAGGTCAAGGCTTACAAGAGACAGTCTGAAGAAGCTGTGAGTTCCTCTTTTGAGAACTTAGACACCTGTGAACTTTCAAGATGTTCTTTTACTGATACAGTTGAATGTGACTTTGCAGGAGGAACAAGCCAACTCTCACCTGTCCAAGTTGAGGAAGGTGCAGCATGAGCTGGAGGAGGCTGAGGAGCGCGCTGACATTTCTGAATCCCAGGTCAACAAGCTCAGAGCCAAGAGCCGTGACGCTGGAAAGGTCAGTTGCATATTACTAGATTCTGTACATTTACTCAGAAGAAAAATGAATTCTTGAATATACACTGATTATTTACATGATTTACATGATATGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20462
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098111 Nonsense 146 232 4 7
ENSDART00000139917 Nonsense 1135 1222 20 23
Genomic Location (Zv9):
Chromosome 5 (position 33894339)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31656571
GRCz11 5 32256724
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAGAGACGTGGAGCTGATGCTGTTAAAGGCGTCCGCAAATATGAGAGG[A/T]GAGTCAAGGAGCTCACCTACCAGGTAAAGACATCAGAGCACAAATTTTTA
Long Flanking Sequence:
ATGCTGAGGAGAAGGCCAAGAAGGCCATCACTGATGTGAGCAACAAAACATAGCAAATATACCACAAAGAACGGATAAACTTAAAAATGTGAAACAAATGCATTTCTGTATGTTTGCAAAAGGCTGCAATGATGGCAGAGGAGCTGAAGAAGGAGCAGGACACCAGTGCTCACCTTGAGAGGATGAAGAAGAATCTGGAGATCACAGTGAAAGACCTGCAGCACCGTCTGGATGAAGCTGAGAATCTGGCCATGAAGGGAGGAAAGAAACAACTCCAGAAACTGGAGTCCAGAGTAAGCAGGATTTGTTTCCCGTGTTAATCATTAATATCTAAATAGTATGTCAAGTTGAACACCTTTTTTGAGAAAATTCAGGAAAGCAACATATTTGGGTAAGGTTCAGCAAAGTATCTCCATTAGGTTCGTGAGCTTGAGAGCGAAATCGATGCAGAGCAGAGACGTGGAGCTGATGCTGTTAAAGGCGTCCGCAAATATGAGAGG[A/T]GAGTCAAGGAGCTCACCTACCAGGTAAAGACATCAGAGCACAAATTTTTATCAAATGAATATAAAATAATTTATGTTCGCTTTATGCAGACTGAGGAGGACAAGAAGAACATCAACAGGCTGCAGGATCTGGTTGATAAGCTTCAGCTGAAGGTCAAGGCTTACAAGAGACAGTCTGAAGAAGCTGTGAGTTCCTCTTTTGAGAACTTAGACACCTGTGAACTTTCAAGATGTTCTTTTACTGATACAGTTGAATGTGACTTTGCAGGAGGAACAAGCCAACTCTCACCTGTCCAAGTTGAGGAAGGTGCAGCATGAGCTGGAGGAGGCTGAGGAGCGCGCTGACATTTCTGAATCCCAGGTCAACAAGCTCAGAGCCAAGAGCCGTGACGCTGGAAAGGTCAGTTGCATATTACTAGATTCTGTACATTTACTCAGAAGAAAAATGAATTCTTGAATATACACTGATTATTTACATGATTTACATGATATGATTTTTTT
Associated Phenotype:
Not determined