Busch Lab

ZMP

bap1

Ensembl ID:
ENSDARG00000063051
ZFIN ID:
ZDB-GENE-050208-492
Description:
Ubiquitin carboxyl-terminal hydrolase BAP1 [Source:UniProtKB/Swiss-Prot;Acc:A1L2G3]
Human Orthologue:
BAP1
Human Description:
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) [Source:HGNC Symbol;Acc:950]
Mouse Orthologue:
Bap1
Mouse Description:
Brca1 associated protein 1 Gene [Source:MGI Symbol;Acc:MGI:1206586]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa24088 Essential Splice Site Available for shipment Available now
sa39360 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa29731 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa31069 Nonsense Mutation detected in F1 DNA Not yet available
sa24087 Essential Splice Site Available for shipment Available now
sa24086 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa24088
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091757 Essential Splice Site 41 724 None 17
ENSDART00000091774 Essential Splice Site 41 278 None 8
ENSDART00000091777 Essential Splice Site 41 755 None 17
Genomic Location (Zv9):
Chromosome 22 (position 10712820)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 10572988
GRCz11 22 10602670
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATATAAGCGCTGTATATTTCATGTAACCTTCCTACATTTTCTTTTTCTC[A/G]GTCCTGTATATGGCTTCATCTTTCTTTTCAAATGGATCGAGGAGCGAAGA
Long Flanking Sequence:
TTAAAATATACAATGGCCAGACAGAATCTGTGATCATTTTTTGCTATTTCTGCGGAGAAGTTTTCTAAAAAATCTGCAGATTTATTTTGGGAGTATCGTAACTAAAAAAAAATTATATATATATAAAAAAAATAGAAGCTTTTTAACTTATATTTAATCTTTACAACGCAAATCCATCTAGATCTATCATATAATATATCAACTAAATATTCATTTACAAACTGTATTGTAAATAAATCATATGAACATTTTCATATTAGACAATAATATTACTGAAATCAACTTAAAAACTGAATAAATATAAATGTACACACATTTACACAAGTAAATAAACTACTTAATACTTGCAAACTGTACAGAAAATTCTAATCAAATGATCATAACTGCTTTGATTTCTTGTTTATAAAGTGATCATTTAAATATATATGTAAAAGCAAAACATATATGTGAAATATAAGCGCTGTATATTTCATGTAACCTTCCTACATTTTCTTTTTCTC[A/G]GTCCTGTATATGGCTTCATCTTTCTTTTCAAATGGATCGAGGAGCGAAGATCTCGGCGTAAAGTCTCCACACTGGTGGATGAAACCTCTGTTATCGATGACGACATTGTTAATGACATGTTTTTCGCTCATCAGGTTAGTCTGTAGAATAGTTTTTTGTCTATACAACAAAATGAAGCCTTAACCCTTATTTCAAGATTGTGTTGTAATCCTAATAAGCACCAAACAAGGTCTGAGGCCATTAAAAAAGGGGTCTCAGTCTGCATGTTTGGTACAAGCCAATGATTGGATTTACACTTAGCTAAAGGAACCACACGGACAAAACAACTGCAGTTTACTAACATTTATTTCTCAGGCTTTTCAGCAAAACCTACAGTGTGTTTGTCGGTTGTTGTGTGCAGTTGATCCCGAACTCCTGTGCGACTCATGCTCTTCTCAGCGTGCTCCTGAACTGCAGCGGTGTGGAGCTGGGAATGACTCTGAGCCGCATGAAGGCTTTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39360
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091757 None 85 724 4 17
ENSDART00000091774 None None 278 None 8
ENSDART00000091777 Essential Splice Site 85 755 4 17
Genomic Location (Zv9):
Chromosome 22 (position 10712685)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 10572853
GRCz11 22 10602535
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCTGTTATCGATGACGACATTGTTAATGACATGTTTTTCGCTCATCAG[G/A]TTAGTCTGTAGAATAGTTTTTTGTCTATACAACAAAATGAAGCCTTAACC
Long Flanking Sequence:
AAGCTTTTTAACTTATATTTAATCTTTACAACGCAAATCCATCTAGATCTATCATATAATATATCAACTAAATATTCATTTACAAACTGTATTGTAAATAAATCATATGAACATTTTCATATTAGACAATAATATTACTGAAATCAACTTAAAAACTGAATAAATATAAATGTACACACATTTACACAAGTAAATAAACTACTTAATACTTGCAAACTGTACAGAAAATTCTAATCAAATGATCATAACTGCTTTGATTTCTTGTTTATAAAGTGATCATTTAAATATATATGTAAAAGCAAAACATATATGTGAAATATAAGCGCTGTATATTTCATGTAACCTTCCTACATTTTCTTTTTCTCAGTCCTGTATATGGCTTCATCTTTCTTTTCAAATGGATCGAGGAGCGAAGATCTCGGCGTAAAGTCTCCACACTGGTGGATGAAACCTCTGTTATCGATGACGACATTGTTAATGACATGTTTTTCGCTCATCAG[G/A]TTAGTCTGTAGAATAGTTTTTTGTCTATACAACAAAATGAAGCCTTAACCCTTATTTCAAGATTGTGTTGTAATCCTAATAAGCACCAAACAAGGTCTGAGGCCATTAAAAAAGGGGTCTCAGTCTGCATGTTTGGTACAAGCCAATGATTGGATTTACACTTAGCTAAAGGAACCACACGGACAAAACAACTGCAGTTTACTAACATTTATTTCTCAGGCTTTTCAGCAAAACCTACAGTGTGTTTGTCGGTTGTTGTGTGCAGTTGATCCCGAACTCCTGTGCGACTCATGCTCTTCTCAGCGTGCTCCTGAACTGCAGCGGTGTGGAGCTGGGAATGACTCTGAGCCGCATGAAGGCTTTCACCAAGGGCTTCAATCCTGAGGTCAGCTCTGTGCATATGCTTAAAAATGGCAACAGATTCTTCTGTGGATCTTCACCCTTGTTGTGTTTTAAAGTCTGTGTGTATTTTTTTGACTTCTCAGAGTAAAGGTTACGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29731
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091757 Essential Splice Site 195 724 8 17
ENSDART00000091774 None None 278 None 8
ENSDART00000091777 Essential Splice Site 194 755 8 17
Genomic Location (Zv9):
Chromosome 22 (position 10710212)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 10570380
GRCz11 22 10600062
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTACCAGCCTGGGGAAAGACTGCTTTAAAGTAATCTTTGTTTATTTTTC[A/C]GGACCATGGGGTGAGGATGAAGAGTGGACAGATAAAGCCAGACGGGTCAT
Long Flanking Sequence:
ACAAAGAACATGAAAAATAACAGAATATTGAACTCTTTATTATTGCTAGTTCCCATTTGAAAGCCGTTCCATTGATTTTGCTTCTGTGGCATTATTGTTATAGTTGTTTAGAAGTGTTTTTAAACCGTTGTTTTTTTTTGTGTGTGTGTGTTAATTATTAACTTTTTTTTAGGGGTTGGTGTGATTAGCCAACTTAGTAGATTTGGTATAAACAATCTTGGTCCTGGTTTAAATCTGTTGTTTTTTAGTTATTGTATTTGTCTTGATTTTATGAAGGCCGGAGCCGCGGCATCTTCCGGAGAAACAGAACGGCATTAGCGCTGTGCGGACGATGGAGGCGTTTCATTTTGTCAGTTACGTGCCAATCAAAGACAGACTGTTTGAGCTAGATGGGCTGAAGGCGTATCCCATTGACCACGGTGAACATTTAGATCCATTAAATACAGATTTCCTACCAGCCTGGGGAAAGACTGCTTTAAAGTAATCTTTGTTTATTTTTC[A/C]GGACCATGGGGTGAGGATGAAGAGTGGACAGATAAAGCCAGACGGGTCATAATGGAGCGAATAGGACTGGCCACTGCTGGGTAAGATGAGTATGAAAGATGAGCTGAAGGTGCTCCATTGGATTGAGTTCTGGTGACTGTGGAGGACATTTGAGTTTTACTGAAATCTGTCCTGTTAAAGAAACCAGTTTGAGCATTCTTATCCTGCCGGAAGTATGAAAGATTGGTTCACTGTGGTCAAAAAGTTGAGTCAGCTGGTACTGAGCAACAAAAGTATCTCCCATTTTACCACCAGAAGGCTGAACCTGTCTGGCAACATCAATCATGAGACATTCAAGTTCACTCGATTCCCCTTTTTTCCCTATTCTGAAACTCTATTTGAACAGCAGATCATCTCAACCATGTCTACATAAATAAATACTAAATAATTGCTGCAACATGATTGGCTGATGTTTATACATTTTTTGATCCTTCTTTAGAGAGCCCTACCATGACATCCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31069
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091757 Nonsense 517 724 13 17
ENSDART00000091774 Nonsense 226 278 6 8
ENSDART00000091777 Nonsense 548 755 13 17
Genomic Location (Zv9):
Chromosome 22 (position 10704051)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 10564219
GRCz11 22 10593901
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCCATGTAGGCCGCGTGCTGTTTGGGGAAGAGGAGGGGCTGCCTAGGT[T/G]AGATGCCCGACACAATCGGGCTGTCCGAGACTTGGGGGTGCTCGTGAGCT
Long Flanking Sequence:
TATTTATTGTTGATAATTTGGGATTGGATTATCAAAATATTCATCTTATAGGTGTAGGTCAAGCCATAGAGTGCATTCTGAATCTTCAATACTTGTGTTTGCAATTAGCAGGGTTCGAAGAAAGTTGGGTCTGCGTACCCGTACCATGAGCCGCACTGCAGTGGGCGGAGTCGCAGCAATGGAGGGTCAACTAGCACTCAGTGTTTTAGCAGAGAAGCTCAAGAAGGAGGTTCAGCGGAAAGACGCCTTGGCCACAACTGGATCCACACCTCTGAACGTACGTACCGAGGGTCGGACAGGTGGCATCAGCATCACCTCGGCTTGCCAGCCGTCGCCCACCCCTAGTAACGAAAGCACGGACACAGCCTCCGAGATTGGTAGTGCATTCAACTCCCCACTGCGGTCACCAGCTCGATCACAGGCGACTACACGTCCCTCCAGCCCAGTGGCTTCCCATGTAGGCCGCGTGCTGTTTGGGGAAGAGGAGGGGCTGCCTAGGT[T/G]AGATGCCCGACACAATCGGGCTGTCCGAGACTTGGGGGTGCTCGTGAGCTCAACACAGCTCCAACTGCAAGAGGATGGAGTCATATTTGCCCTGCCACCTACAGGTACGCATTCAAAACTACAAGATTTAACTAGAGATGCACTGATTGACAAACTAAGGACTGTCATTTTTGCTTGCCCCGTGATCATCTGGAAAGTTCCAGCTGAACTGAAGCTAACTTTGATCTCATTTGACAGAAGCATTGGAGGGGTTGAAGAAAGTGGGTGGTGTGGATAAGAAGAAGAAAGAAGAGGCGAGTGGTCCAGGAGGGGAGGAGGAGGTGAAGGAGGGACCATCAGTGGAGATGAAAGCAGAGGACGTCAAAGAGTCAGTTGACGTCAAACCTGAGAAGGAGAACCTGCCGACCACTGATGTTGAGAACAGCACCAAACCTCCTGGGGAAAAATACACTCCTAAGGTAAGACGGTGACCGTTTATTTGTCAAATCATGGTTAAATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24087
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091757 Essential Splice Site 551 724 13 17
ENSDART00000091774 Essential Splice Site 260 278 6 8
ENSDART00000091777 Essential Splice Site 582 755 13 17
Genomic Location (Zv9):
Chromosome 22 (position 10703946)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 10564114
GRCz11 22 10593796
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAGCTCCAACTGCAAGAGGATGGAGTCATATTTGCCCTGCCACCTACAG[G/A]TACGCATTCAAAACTACAAGATTTAACTAGAGATGCACTGATTGACAAAC
Long Flanking Sequence:
TAGCAGGGTTCGAAGAAAGTTGGGTCTGCGTACCCGTACCATGAGCCGCACTGCAGTGGGCGGAGTCGCAGCAATGGAGGGTCAACTAGCACTCAGTGTTTTAGCAGAGAAGCTCAAGAAGGAGGTTCAGCGGAAAGACGCCTTGGCCACAACTGGATCCACACCTCTGAACGTACGTACCGAGGGTCGGACAGGTGGCATCAGCATCACCTCGGCTTGCCAGCCGTCGCCCACCCCTAGTAACGAAAGCACGGACACAGCCTCCGAGATTGGTAGTGCATTCAACTCCCCACTGCGGTCACCAGCTCGATCACAGGCGACTACACGTCCCTCCAGCCCAGTGGCTTCCCATGTAGGCCGCGTGCTGTTTGGGGAAGAGGAGGGGCTGCCTAGGTTAGATGCCCGACACAATCGGGCTGTCCGAGACTTGGGGGTGCTCGTGAGCTCAACACAGCTCCAACTGCAAGAGGATGGAGTCATATTTGCCCTGCCACCTACAG[G/A]TACGCATTCAAAACTACAAGATTTAACTAGAGATGCACTGATTGACAAACTAAGGACTGTCATTTTTGCTTGCCCCGTGATCATCTGGAAAGTTCCAGCTGAACTGAAGCTAACTTTGATCTCATTTGACAGAAGCATTGGAGGGGTTGAAGAAAGTGGGTGGTGTGGATAAGAAGAAGAAAGAAGAGGCGAGTGGTCCAGGAGGGGAGGAGGAGGTGAAGGAGGGACCATCAGTGGAGATGAAAGCAGAGGACGTCAAAGAGTCAGTTGACGTCAAACCTGAGAAGGAGAACCTGCCGACCACTGATGTTGAGAACAGCACCAAACCTCCTGGGGAAAAATACACTCCTAAGGTAAGACGGTGACCGTTTATTTGTCAAATCATGGTTAAATTACGCGATGTCACATAGAAGGGTTTCTCTCAAACAGGAGTTGCTAGCTTTGCTGAAGTATGTGGAAGCAGATATCGCCAACTACGAAGTGTATTTGAAAGAAGAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24086
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091757 Essential Splice Site 657 724 16 17
ENSDART00000091774 None None 278 None 8
ENSDART00000091777 Essential Splice Site 688 755 16 17
Genomic Location (Zv9):
Chromosome 22 (position 10703355)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 10563523
GRCz11 22 10593205
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAGGATTTTGTCCTCAAAGTATGGAATGAGCTTATTGAGATATGTTTTC[A/T]GATTGATGACCAGAGGAGGACTCATAACTATGACGAGTTTATCTGCACCT
Long Flanking Sequence:
AGTTCCAGCTGAACTGAAGCTAACTTTGATCTCATTTGACAGAAGCATTGGAGGGGTTGAAGAAAGTGGGTGGTGTGGATAAGAAGAAGAAAGAAGAGGCGAGTGGTCCAGGAGGGGAGGAGGAGGTGAAGGAGGGACCATCAGTGGAGATGAAAGCAGAGGACGTCAAAGAGTCAGTTGACGTCAAACCTGAGAAGGAGAACCTGCCGACCACTGATGTTGAGAACAGCACCAAACCTCCTGGGGAAAAATACACTCCTAAGGTAAGACGGTGACCGTTTATTTGTCAAATCATGGTTAAATTACGCGATGTCACATAGAAGGGTTTCTCTCAAACAGGAGTTGCTAGCTTTGCTGAAGTATGTGGAAGCAGATATCGCCAACTACGAAGTGTATTTGAAAGAAGAAGTGGAAAAAAGGAAGAAGTACAAGGTAGGTGATTGATTCCTCACAGGATTTTGTCCTCAAAGTATGGAATGAGCTTATTGAGATATGTTTTC[A/T]GATTGATGACCAGAGGAGGACTCATAACTATGACGAGTTTATCTGCACCTTCATATCAATGCTTGCACAAGAAGGTAAAAAAAAACATTAATTCTTCCACAGAACACAAAAATAAGATATTTTTGAATAAGATATATTCATGATGGCAGTGGGAACATTCTGCTAAATATCTCCTAGTGAGTTTTAATAATTGTTTTCAGTAAATTAATATTATGAAAGTCAATGGATTTTCAATATACCATCTTTTCTGTTCATCACAAGAAATAAACTGAAATATGTTTCAAACAAGCAAAGTGTCAGTAAATAATAATCGATTAATATTTTGGGTGAACTATCCCTTTAGCAAGCTATGAGTTGCACCAAAATGAACTTAAATACATTTTCAGTCAATTATTTTATTGTAATCAAATGTGCCTTTGGTGGTTTGCAGGTATGTTGGCGAGTCTGGTGGAGCAGAACATCTCTGTGCGTCGGCGACAAGGCGTAAGCATCGGTCGGCT
Associated Phenotype:
Not determined