Busch Lab

ZMP

LOC557734

Ensembl ID:
ENSDARG00000070074
Human Orthologue:
LRP8
Human Description:
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor [Source:HGNC Symbol;Ac
Mouse Orthologue:
Lrp8
Mouse Description:
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Gene [Source:MGI Symbo

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa33898 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa30873 Nonsense Mutation detected in F1 DNA Not yet available
sa20743 Nonsense Available for shipment Available now
sa20742 Essential Splice Site Available for shipment Available now
sa33897 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa33898
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102554 Essential Splice Site 147 984 4 19
Genomic Location (Zv9):
Chromosome 6 (position 35143296)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34698235
GRCz11 6 34681618
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAGAAAGAGACTGTGAAAATGGAGCAGACGAGGAGCAGTGTGCCGCAGG[T/C]AAGACCACAGAGAGAAAAAGAAATGGCTAAAAATAGAGCCTGTCTGGATA
Long Flanking Sequence:
CACAGGACACTAAAGAAACAGCCAAAGAAAAGCAAATCTTTGCCATCACAGGAATAAATTATATTTTAAAATATTTTGGATTGGAAAGCAGTTGCATTTTTATAATATATCTTATATTACAGTTTTGCTGTATTTTTAATCAAATAGCCAATTCCTCTTTGACGCATAGGCTATAGACTTCAAATATTTTAATGTGAATATATGCCCATATAAATATATAATTTATTTTAATGAAAATATGTCACTGTATTGTATATTGTATATGCAATTTGTACATAATGTGTTGTACATAGCATCTGGAAACTACACATTTTTAATGTTAGTTGATACAGTATGTCATCCTTTAAAATGTCTCTGCTGTTGCTCACAGGTCGCCAGACGTGTCCGCCAGAGAAGTTTGACTGTGGCGGCTCAACCAGCAAGTGTGTGTCTTTGTCATGGCGCTGCGATGGAGAAAGAGACTGTGAAAATGGAGCAGACGAGGAGCAGTGTGCCGCAGG[T/C]AAGACCACAGAGAGAAAAAGAAATGGCTAAAAATAGAGCCTGTCTGGATAATGCATAGTCAGACTTCAGTGCGGTATGTGGGTGAACTTAATGGAGCGAGGTGTAGGTTGGGTGTGCATGTGTGTTCGTGTGTGCATTTTTGAGTGTGCCAGTGCGTGTGTGTGTGTGGGGGGGGGGGGGGAGGCCTGCTTGTGTGTGCGCGAGTGCATGGAACACATGAAACACTGATGTTGGAAGTTATCGTCGATCGATGTTCAGGAAAGATATTACAGATTGCCCTGTTTTAAAAATTGGATGAAATTTTTGTAACACTTCCTATGACGCTCATGCTTGTAATGAATTATAACTCTGTTTATGATTATTTATAATCAAGCATAATAATTCTAAAAATGCATTTATGTAATGCATTTATAATAGTGGTATTAATACTTATTGGTAATTCATTTTATTGTTCAATATACAGTTGAAACCCGAGGTTTACAAACACTCTAAAAAAAAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30873
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102554 Nonsense 297 984 6 19
Genomic Location (Zv9):
Chromosome 6 (position 35105825)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34735703
GRCz11 6 34719086
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCCTGATCAGTTCCAGTGTGGCGACGGCTCCTGCATTCACGGCACTAAA[C/T]AGTGTAACAAAGTGCACGACTGTCCAGATTTCAGCGACGAGGCCGGCTGC
Long Flanking Sequence:
TTCCAAAACTGTCAACTTTTTTTCACAAAAACTTTAAACTTTCACAAAGTCATAAATTCTTCAATAAACCACTGTTGAATAATAATAAAAACATTTATGTCCAGTCATTCCACCCAGGTTTTTAGAATACCAATGGTTAGTGAGATGAAAAAAATATATACATTTTACAAGATTTTAGTGTGTTTTCACAAAACACAATAATTGAAGCAAATAAATCTATAGATTTGGTGAAAAGCTATCACTAAATCAGTCATTTTATGCTGCATATATATATATATATATATATTAGCTCCAACTTAAACTGGGATTAAGCCAGATTCTGCTCCGCAATTTCCTGCTGCCATGATAATCTCCAAAAGATTGCTTGCTTAATTGGCCAGGCTGATAAATAAGAAAACAATAGTCTCACATGCGAATTTGTTTTGTGTCCTGCAGCTGTGTTGACCTGCCGTCCTGATCAGTTCCAGTGTGGCGACGGCTCCTGCATTCACGGCACTAAA[C/T]AGTGTAACAAAGTGCACGACTGTCCAGATTTCAGCGACGAGGCCGGCTGCGTCAACAGAAGTGAGTAGCTTCAACAGTCTCCCATTTGATTAGCCTCTTCATCTCGCCTCTATTCCAGCAGCGTTTTTCACTGAAGATGAAAGGCTAGAGTGAGCCCAATCATGCGGCCCCAATCAACTTAACATTCACACAAAGCACTTCGAGACCAAGCAGATGTACTCCTACATGATGCCAGGGTTCTGTGGCACACTTCCCATATGGCACCTTCAATCAAAATCACCTTGAAAGATTCATTATTCCATGGTTATATCTGGTGATTGATGCATAACACGATTTATTTTGAGTACATTGGATCATAATTCATGTCGACCAATTAGTGCCCTGTGTTTGTATTTGGTTAGGTTTATGGATACTATCAGGGCTTTACATTAACTTTTTTAGTCACTGGCCACTTTGGCTTCTAGTTTTCCAATGTTACTAGCCACTCTGCATTTTTGCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20743
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102554 Nonsense 388 984 8 19
Genomic Location (Zv9):
Chromosome 6 (position 35090709)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34750819
GRCz11 6 34734202
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATATGTAAAGACCGGCAGATCGGCTTCGAGTGTCAATGCCCCTCGGGCTA[C/A]AAGCTCCTGGACAAGAAGACTTGTGGAGGTAACATCAATACTGCTTCACA
Long Flanking Sequence:
TTAAACAGAATTATTTGCAGTTTTGTCCTATTATTATTATTATTATTATTTATTTATTTATTTATTTATTTTTTATTATTATTATTTAGGTTGCATCAATGTCAACTCTAATGTGAAATTTTCTGTCTGGTGGTTTATAGTGGTTCATGTCACTAGAAAAAGAGAATCATTATTGTAGCCCTAAAGTGTGTGCGTGCGTGCGTGTTTGTGTGTCTGAGAGCATTTTTTTCCCCAGTCTGTCATGATTGATTTTTTCATAAAGTGTTCAAGCTCAGCCTAGAGAATGAGAACCAAGCAGTCTAGCCGTCAGATGTGTCAGTTTGCCATGAGCTTTTACAGTTAAGTTTCTGCCAGTCATTGTGACCTTTGACACCACCTTTCTTGTTTTTGTTATTTTTTTCCATTACAGGACTGAATGAATGTGCCATAAACAATGGCGGCTGCTCTCACATATGTAAAGACCGGCAGATCGGCTTCGAGTGTCAATGCCCCTCGGGCTA[C/A]AAGCTCCTGGACAAGAAGACTTGTGGAGGTAACATCAATACTGCTTCACATACTGACCTTTTGATGCTACACAGCCCTACATTGTACCCACTTTCCCAAGAGCCAACATTGCAAGCATCTATGATTTGTTTACTCTTAGCGTCATCACTTTGATAGTCGTGAAATCCCCAGATGGCGTTTGCAAGCATCATTTATCTTGTCTGAGGACACTGCACTACAAAAGCCTCTGTTCTCTCTGTCTCTCTGCTCTGTTACTAATGCTTTTCTGATGGTCCTCGCCAGACATAGACGAATGCGAGAACCCAGAGGCCTGCAGTCAAATATGTATCAACCTCAAAGGCGACTACAAATGCGAGTGTTACGAAGGCTACGAGATGGACCCAGTTACCAAGACGTGTAAAGCAGTGGGTAAGACAGTATACATTAACATCTCCATCAATCACTTTTCTGAACAGTGTGGCCTGATATAGCTGACTTTTTCCAGCCCAAAAGCACAAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20742
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102554 Essential Splice Site 440 984 9 19
Genomic Location (Zv9):
Chromosome 6 (position 35090299)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34751229
GRCz11 6 34734612
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACGAAGGCTACGAGATGGACCCAGTTACCAAGACGTGTAAAGCAGTGGG[T/G]AAGACAGTATACATTAACATCTCCATCAATCACTTTTCTGAACAGTGTGG
Long Flanking Sequence:
ACTGAATGAATGTGCCATAAACAATGGCGGCTGCTCTCACATATGTAAAGACCGGCAGATCGGCTTCGAGTGTCAATGCCCCTCGGGCTACAAGCTCCTGGACAAGAAGACTTGTGGAGGTAACATCAATACTGCTTCACATACTGACCTTTTGATGCTACACAGCCCTACATTGTACCCACTTTCCCAAGAGCCAACATTGCAAGCATCTATGATTTGTTTACTCTTAGCGTCATCACTTTGATAGTCGTGAAATCCCCAGATGGCGTTTGCAAGCATCATTTATCTTGTCTGAGGACACTGCACTACAAAAGCCTCTGTTCTCTCTGTCTCTCTGCTCTGTTACTAATGCTTTTCTGATGGTCCTCGCCAGACATAGACGAATGCGAGAACCCAGAGGCCTGCAGTCAAATATGTATCAACCTCAAAGGCGACTACAAATGCGAGTGTTACGAAGGCTACGAGATGGACCCAGTTACCAAGACGTGTAAAGCAGTGGG[T/G]AAGACAGTATACATTAACATCTCCATCAATCACTTTTCTGAACAGTGTGGCCTGATATAGCTGACTTTTTCCAGCCCAAAAGCACAAAAATAAAACACCCAAAATATTAAAATAACTATTTAAATCAGAAATTAGCCTAGTTATTGTAATGTGAAGTGGGACGCTGTCAAAGGAGTGTGGATCCAAATGCAGGGTTTTTTATGCAGAGAATAGTCAGGCAAGCAACAGTCAACACAGAAGCAAACAGATGTTTACGGGCAGTCAAGAGTCATGGTCAATAAACAGGCAAATGGTCAAAGTCAGGCAGCAGACAGGAATAAACATACAAACAAACAAACAAAGCAAGGGTCTAACACGGAAAGCAAGGCTTTCACTCACAGATAAAACAAGACTCAGCACTGATGTGTGTGTCTGTGCTGTTTTTAAAGTCCATCTAATCAGTCTTTGAACAGCTCCCAGCTGTGTGAGTGTAATCAGTCGTGGTCTGGAATGGGTGTGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33897
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102554 Nonsense 484 984 10 19
Genomic Location (Zv9):
Chromosome 6 (position 35071933)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34769595
GRCz11 6 34752978
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCCGACCCTGAAGAATGCTGTGGCCCTGGATGTGGATGTTACCACCAAC[A/T]AGATGTACTGGTGTGACCTTTATCATCGCAAGATCTTCAGGTACACACAC
Long Flanking Sequence:
TCATTATTTACTTACCATTCACTTGTCGTAAACATGTTTGTGTTTCTTTTTTCTGTTGAACTCAAAACAAGATATTTTGAAAAATGCTGAAAACCTGTAACCTTTGACTTCTATAGTATGTGTTTTGCTACTATGGAAGTCAATTGTTACAGATTTTTTACATTTTCAAAACATTTTCTTGTTTTGTGTTCAACAGATTAAAGAACTCATAGATTTTGAAACCACTTGAGGGAGAGTAAATACTGAATTTAAATTTTTGGGTGAACTATCCCTTAAAATATACTATTAAACTGTTTATCAGCTCAGTCACCTATTCCTGATCCCATGTTGACAAATGGCCTGATGAACAATTTTCTGGTCCCTTCACAGGTAAGAGCCCATACCTCATGTTTACTAACCGCCATGAAATCCGCCGCATTGATCTGTTGAAGAAGGACTACACACAAGTGGTGCCGACCCTGAAGAATGCTGTGGCCCTGGATGTGGATGTTACCACCAAC[A/T]AGATGTACTGGTGTGACCTTTATCATCGCAAGATCTTCAGGTACACACACAGCATTACAGCACAGGGCATATTGCGTTCCTCCCTCTAACTTGACAGCTGTTTAATCTTTGTTTGAAAAGGATAATTTGCAATTAGTGTAGAGCGCTGAGGTAGGAGAAGATGTTGCGGTTCTGAGAAGCTCTTCCCGCCTCCTCTCAGCTGTCTGATATTTAAATGCATGAGAACAGCTGCTGCAGAATAACTGGAGATTTCCTGACGGCAGCATCATCATGCAGTGATCAATTGAAAGCTGTGCAGGAAATTGCTTGTGTGCACATTTCCATATAGACTTTATTCTCTGGTTTCCTAGGAGTTGGGATGAAAATGTAAAAAATTACACAAACAAAACAGCTGTACGTGAGGAATTATTTTAGGTTTTTGGGTACAAAATTTATTTTTATTATTTGGTTCTTGTTTTTGATTGTTTGTATTTATTTATTATCAGATCTCAATTCCTCTG
Associated Phenotype:
Not determined