Busch Lab

ZMP

ezh1

Ensembl ID:
ENSDARG00000037894
ZFIN ID:
ZDB-GENE-050114-1
Description:
Enhancer of zeste 1 [Source:UniProtKB/TrEMBL;Acc:A5XBQ4]
Human Orthologue:
EZH1
Human Description:
enhancer of zeste homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:3526]
Mouse Orthologue:
Ezh1
Mouse Description:
enhancer of zeste homolog 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1097695]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa30837 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33250 Nonsense Mutation detected in F1 DNA Not yet available
sa14932 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa30837
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000039170 Essential Splice Site 168 681 None 16
ENSDART00000101965 None None 147 4 4
ENSDART00000112583 None None 153 None 5
Genomic Location (Zv9):
Chromosome 3 (position 36863231)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 36726591
GRCz11 3 36868449
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTTGGAAGAGCTTATTGACAATTATGATGGTGTGCATGGAGACAGAGG[T/C]GAGCAGCACAATATGTGTACATGTAAACATCACGAGAGCTGGGATGCACT
Long Flanking Sequence:
GCGCACACACATTAGCACATATGAAAGCACTCAATCATAATCACCATTAGAAGCCTGCATGTGCAGAAACACAAGGAGAAAGAAAAGCATCAGTGTATGACAGTGGTCATTTTGAAAGTAGGTCACCAGCAGCAGTGCGTTCACATGTTCTGACAGCATGTGTTTTTAAAAGCATCTCTCAGGTAGAGGAGGGATGTGCATCTTTAAACGCCTACACACACGTACAGCCTCAAATGTAGGCATCTACTAAAAACACCCACCCGCAACAGGCATATACAGTCTTGTTATGCATTTATCTCTCATTCAGAAGGATCTCGAATACGCACAAATGTTTGTATTAAAACATGTTTGTATGTAAATCAATTTCTCTTTGTCTCTGAGGTGGAGGATGAGACGTTTCTGCATAATATCCCCTACATGGGAGATGAAGTGTTGGAACAGGACGAGGCTTTCTTGGAAGAGCTTATTGACAATTATGATGGTGTGCATGGAGACAGAGG[T/C]GAGCAGCACAATATGTGTACATGTAAACATCACGAGAGCTGGGATGCACTTCTTCTAGAAAGCTCTGAATGCTTTGAGGACATAGGGCTCTATTTTAACGATCTAGGCGCAAAGTCTAAAGCGCATGGCGCAAAAACATTAAGGGCATGTCCAAATCCACTTGTTTATTCTCTTAATGAGTTATGGGTGTGTTTTGAGTATAACATGCATTAAACCAATCAGAGTCTCATTTCACATTCGCTTTAAGAGTCAGTTGCATTACGCCATGGTCTATTTGCTTTTTACATGGTGGACATTGTAAGAGGAAAAACCGGATGCTTCACTTGCAAGAAAACAGTTAGCAGCACAAGGATAAAGAATGAGCCTCCTCGATTCGGCCTCTTTACTTTCTCTTTACTATTACTCTTTATTTTATTCTTTTACTTTCCTAGATAAGGAAAGGGTACGCACTCCACTAAAGACATCCATTAGCCTACAACTTTAGTTTTGTTTGTTAAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33250
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000039170 Nonsense 523 681 13 16
ENSDART00000101965 None None 147 None 4
ENSDART00000112583 None None 153 None 5
Genomic Location (Zv9):
Chromosome 3 (position 36881184)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 36744544
GRCz11 3 36886402
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTTTCCTGTTTGTCTTACAGATAACTCCTCCAATCAAGTGTACAATTA[T/A]CAGCCATGCGACCACCCCGAGCACCCGTGTGACAGCTCCTGCCCATGTGT
Long Flanking Sequence:
TAAAGGCTTAACTAGGGTAATTAGGTTAACTGGGCATGTTACGGTAATTAGGTAAGTTGTTGTATAACAATGGTTTGTTCTGTTGACTATCAGAAAAAATATAGCTTAAAGGGGCTAATGAATAAAAACTGCTTTTATTCTAGACGAAATAAAAAAAATAAGACTTTGTCTGGAAGAAAAAAAATATTATTAGACATACTGTGAAAATTACTTACTCTGTTAAACATAATTTGCCAAATATTTAAAAAAGAAAAAAAAAATCAAAGGGGGCTAATATTTCTGACTTCAACAGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTATTATTATTATTATTATTATTGTTAAATTATTTAAACATTAAGTGTAGTTTTTGAAAAGCTTTTTGCTGTTAATTCCTTTCCTGTTTGTCTTACAGATAACTCCTCCAATCAAGTGTACAATTA[T/A]CAGCCATGCGACCACCCCGAGCACCCGTGTGACAGCTCCTGCCCATGTGTGATCACACAAAACTTCTGTGAGAAATTCTGCCAGTGTGATCGCGAGTGTGAGTTCAGCACAAATAAACACAGTCACACATGCCAACCCAACACATGAGATATGCACATACAAATATACAATTTCAGGTATACAGTGCTGCAATATTCAATTCAATTCAATGTGTTGAAAAAATCTTCTCTCCATTAAATAGAAATTGGTGGAAAAAATAAACAGGAGGGCAAATAATTCAGGGGGCTAATTATTCTGACTTCAACTGTATAATAATATATGTATATGTATGTATGTGTGTGTTTTTATGAAGTTTGAAGGAACATTGCTGTAGTTCTTATGCTTTACCAACCCGATTTCTCTCTCTCCCTCCATTTATTTTATTATAATATTGTGTGTAAAATGTCTATTTTGAGTATTTCAGGCCATTGGCCAATTAATGCTAACAATAAGGTACAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14932
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000039170 None None 681 16 16
ENSDART00000101965 None None 147 None 4
ENSDART00000112583 Nonsense 151 153 5 5
Genomic Location (Zv9):
Chromosome 3 (position 36884642)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 36748002
GRCz11 3 36889860
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
KTACAGTTGTCRTGGTTAATGGTGATCACCGCATCGGAATCTTCGCTAAG[C/T]GAGCCATACAGCAAGGAGAAGAGCTCTTTTTTGATTACAGGTGGGTTTGY
Long Flanking Sequence:
ACCCAAACTGTTACGCGAAAGGTACTTTATTTATATATATATATATATATGTATATATATATATATATATATATATATATATATATATATATATATATATATACACACACACACATTTAAAGTCAGAATTATTAGCCCCCCTCTGATTTTTTCTTTTTTAAATATTTACCAAATGATGTTTAACAGAGCAAGGAAAATTTCACAGTATGTCTGATTTTTTTTCTTCTTGTAATAAACTAGTAAACTAGTAATTAAAACTATTTTGTTTAGAAAAGTGTTAAAAAAAAAATCCTTTCCGTTAATCAGAAGTTGGAGAAAAAAATAAACTGGAGGGCTAATAATTTAGGGAGCTAATAATTCTGACTCCATCTGTGTAAATGTCATATCTAATATGAATATAATATAATATAATATGAAACATAATGTATACTGGTTTGTTATTGGTTATCATTACAGTTGTCATGGTTAATGGTGATCACCGCATCGGAATCTTCGCTAAG[C/T]GAGCCATACAGCAAGGAGAAGAGCTCTTTTTTGATTACAGGTGGGTTTGTTTGTCTCAGCAACACCTTAAAGGTTTAAGACACCCTGGAGTACTTTTTTTTAGAAATTTTAACAGATTTGTGTGTGTTGAGCATCAGTTAAGACAACGTTAACACCGGTCAGCTTTAATTGTGTGGAAAACTAGAGAATTTTAAGCCTTTGTTAGCTAATTTCATCTTTCGGGTTTAAAATAATTTTTGGGGAGGGATCAAAATCAGTGACGTATCGTGAATCTGCTAGTGAAGTGATGATGTGTCGGTTTCTCATTATTATTCATAGCGGCGTTTTCTTATCATGGATTATCTTAGCATGGCAAGCAGTATTCATGAAGTGTCGAAACGTTGTGTTTGTTTCCATGATCCACAGGGTTTGTTGCTAGTTTTTCCCTGTGATTCTGTTAGAGCCGATACAACAAAGCTGTTGGTTTGCAGCAAGCATTTTGATCAGGAGAACTGTATGAG
Associated Phenotype:
Not determined