ZMP

nfs1

Ensembl ID:

ENSDARG00000062237

ZFIN ID:

ZDB-GENE-060405-1

Description:

cysteine desulfurase, mitochondrial [Source:RefSeq peptide;Acc:NP_001038458]

Human Orthologue:

NFS1

Human Description:

NFS1 nitrogen fixation 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:15910]

Mouse Orthologue:

Nfs1

Mouse Description:

nitrogen fixation gene 1 (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:1316706]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa8913	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa30659	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa8913

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000089747	Essential Splice Site	102	451	3	13

Genomic Location (Zv9):

Chromosome 11 (position 25283110)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	24111935
GRCz11	11	24349551

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TCATGCCTATGGATGGGAGAGCGAGAGCGCAATGGAAAAAGCAAGAAAAG[T/C]ATGTTWAGATGACTGCTTGTTTTATTTGAAAATRATAGTTTTCTTGATTT

Long Flanking Sequence:

TCATTGATTGAACAATGTTGTACTTTGATAGTCATTGACTGCTAAAATCATGTCCTTATGTAGAATTTGCTTATAATACTTTTCTGAAATGATATTATTAGGGTAAATGACCGAATGTGCGAATATAAAACAAACTTTACCTCAATCAAACATACCTGTCTGTCTCCACAGAGTTGATCAAAAGTAGGGAACTGGAGAAGGATGAGCTGAGACCACTTTATATGGACTTTCAGGCCACCACACCAATGGTACCCTCTGCTTTTGTCATCCTAGATTAATGAACTTATCAAACTCATGAATCTAATACATGATGAGACATTTTCTGGGATGTTTACATGTCATTGTTTCTAATGAACAATGTTGTTTATATCTGACTCAACAGGACCCGAGGGTTTTGGATGCCATGCTTCCCTATCAAGTGAACTATTATGGCAACCCACATTCCAGGACTCATGCCTATGGATGGGAGAGCGAGAGCGCAATGGAAAAAGCAAGAAAAG[T/C]ATGTTTAGATGACTGCTTGTTTTATTTGAAAATAATAGTTTTCTTGATTTGGAAATATGGGAGCTTTATTTTCAAGTCAAAGCGTAATGTTTTGGTCAAGCCAAAAATGTACTGTTTACTGTTAAGCCATTGTTTATTATTTCCTCTTCAGCAAGTAGCAGGTCTTATTGGTGCCGACCCGAGGGAGATTGTGTTCACCAGTGGTGCGACTGAGTCCAACAATATGTCAATCAAGGTAAGTATGTCACTGTGAGGCAAGATTAGGATTAGGAAGTGGAACGTTGGAACACAAATGACTCAGCATTTTTAAAAATAGACAAATAGGGGAACTTCAGAATATTACAAAGAATAATCAAACATCTTTGACTGTTTTTCATATTTTTAGGGTGTTGCTCGGTTTTATAAGGCTAAGAAAATGCACATCATTACCACCCAAATTGAGCATAAGTGTGTGCTGGACTCCTGCCGGGTTTTGGAAACTGAGGGTTTTGATATAACGT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa30659

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000089747	Essential Splice Site	401	451	11	13

Genomic Location (Zv9):

Chromosome 11 (position 25286768)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	24115593
GRCz11	11	24353209

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCCTCAGAGCAATAGGAGCAGATGAGGATTTGGCTCACTCTTCTATTCGG[T/C]TGGTGGTCTTCATGTAACATTAGTTTAAATGTTTATTGTGCCTTCATGTT

Long Flanking Sequence:

CCACTTTAACTGACATTTGCACCAGTTTTGCACATTTGCACCAGACACTTTTTTTAGTCACTCAATAATTAAAAAAACAAAACCATTGTAAATCTATAAAGTGTGCTTCGAACAGGTGAGTGAGCTTGACAAAACACTCTTCCTTACTCTAGCAGTTAATTGTATCAGCACAAACAGTTCCTTTAGCACTTTTTGTTTATTGCCTAACACACATATAGTTTGACTAAATGTAAATGTAGAAAAATAAGAGCTATAGCGGTTTCTCCAGTTGCAATGATGAAAACAAAATTCTGAAAATAGTATATGTGTAATGATGTAAATAATATGTTATATTCTCTTTTGTAGTTCAAATAGCAGTTTCGTGTGAAATGCAGTGAGTGTCTGCTAGAGTGATGAGCTGTGTTGTTGTTTTCAGCGCCTGCACGTCTGCTTCACTGGAGCCCTCATATGTCCTCAGAGCAATAGGAGCAGATGAGGATTTGGCTCACTCTTCTATTCGG[T/C]TGGTGGTCTTCATGTAACATTAGTTTAAATGTTTATTGTGCCTTCATGTTGTGTAATCCGTGTCCAGATTTGATCTCAAGTCAGAATGCTTAGATTTCCTGTTTGAAAACCATGACCACACACACACACACAAATGAGAGCATGTGATGAACACGAGCTCTGCTTTTCTCAGGTTTGGCATCGGCAGATTCACCACAGAGGAGGAAGTGGATTATACAGCAGAGAAATGCATTCATCAGGTCAAACGGCTCAGGGAGATGAGGTGAGAAAAGACCAATGAATGAGGAAAATTCAATACAAGATCTTTGGTGACAGCAAAAGTCTGAAAATCAAGCACCCATTGAAATACTCATTGGAAAAAACTGGAGTTTTGCTTGCAGTATTACAAGACTATGGATGGATGGATGGATGGATAGCGGGATATATATAGGTATATATAGAGGGATAAATGGATAGATAGATGGATAGATAGATAGATAGATAGATAGATAGATAGATAG

Associated Phenotype:

Not determined