Busch Lab

ZMP

zgc:136888

Ensembl ID:
ENSDARG00000069260
ZFIN ID:
ZDB-GENE-060421-4898
Description:
meiotic recombination protein REC8 homolog [Source:RefSeq peptide;Acc:NP_001035468]
Human Orthologue:
REC8
Human Description:
REC8 homolog (yeast) [Source:HGNC Symbol;Acc:16879]
Mouse Orthologue:
Rec8
Mouse Description:
REC8 homolog (yeast) Gene [Source:MGI Symbol;Acc:MGI:1929645]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa30055 Nonsense Mutation detected in F1 DNA Not yet available
sa10120 Essential Splice Site Available for shipment Available now
sa45821 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa30055
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100644 Nonsense 274 564 10 18
Genomic Location (Zv9):
Chromosome 24 (position 12623241)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 12574978
GRCz11 24 12721272
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGATGAAGGTAATGGACGTTTTACAGAGGTCACCTTAGACCGAGTCGCTT[T/A]AGAGATGACGCCTCCCCCAATCACTATGACAACAACCACGGACGCCAGCG
Long Flanking Sequence:
AGCGCGATCGGTTGATTCACATATGCCAAACGAACCATGCTAAAACTGGGCAAATGTGACAGGTTTCGAAACAAAAGTCTAGGAGTGAAAACACCCTTAAAGTCTTAAAAGCTATTGAAATTCACTCTCTGATTCCTGTATATACCCTGATTAACTAATACATCCTTAATGTAAAGTGTTTTTGATTTCTGTATAGTACAGACCTGTCACGAAAGTCAAAATCAAATGGTCAAACAGACTCTTGGTTTGGGTTTGAGACCTAACATAACATCAGTTTGCATAGACAGTGACAGTTGTTGGGCCAAATGTCCTTGACCTAAAAAGTCTGAAATAAAGGGTCTGCTTGACCTCTGCTTGCCTGGAATGGCTGCTTGTGTTGAATGTAGCTCTCAAAGCTTTCAATCATCTCTGAATGTATGTTCACAGACTGAAGAACAGCGAGTGCCTTATGGATGAAGGTAATGGACGTTTTACAGAGGTCACCTTAGACCGAGTCGCTT[T/A]AGAGATGACGCCTCCCCCAATCACTATGACAACAACCACGGACGCCAGCGAGAGAGATGTGGAGATGGAGTCCAGTGAGGTTGGTGTCTGTATTACCTTGCCCATTATACTCAAGTGTTACATAATCCATATGTGTTGTGAAGCGTGAAGTTACATTGGCCTGAATCCACAACAATGCACTGGTGTTTCGATAACCTCTTGCTCTTCAATCTCATTTTTCCCTCTATTTCAGACTCTCACAGCCGAGCAATCTGTGCCTCTGAAGAGACGAGGTCGCAAAAGGCAACTGATTTTCGCCGACCAAAACACACAGATTTCCCAGGATGCAATGCGACAACAAATCAACAACCCTCTGACTGAAACTCAATCTCTGGTGGGAGGCCTGTGATAGATAATCTAATCACTAATGCTGGGAATCCTTTGACAACTCCTGATTTGATTCTATGAAGGTTCAGGGAATCAGGGTGTAATTACAAAAACAATTCTTGATTCTTCTCAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10120
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100644 Essential Splice Site 300 564 10 18
Genomic Location (Zv9):
Chromosome 24 (position 12623321)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 12575058
GRCz11 24 12721352
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAACAACCACGGACGCCAGCGAGAGAGATGTGGAGATGGAGTCCAGTGAG[G/A]TTGGTGTCTGTATTACCTTGCCCATTATACTCAAGTGTTACATAATCCAT
Long Flanking Sequence:
AGGAGTGAAAACACCCTTAAAGTCTTAAAAGCTATTGAAATTCACTCTCTGATTCCTGTATATACCCTGATTAACTAATACATCCTTAATGTAAAGTGTTTTTGATTTCTGTATAGTACAGACCTGTCACGAAAGTCAAAATCAAATGGTCAAACAGACTCTTGGTTTGGGTTTGAGACCTAACATAACATCAGTTTGCATAGACAGTGACAGTTGTTGGGCCAAATGTCCTTGACCTAAAAAGTCTGAAATAAAGGGTCTGCTTGACCTCTGCTTGCCTGGAATGGCTGCTTGTGTTGAATGTAGCTCTCAAAGCTTTCAATCATCTCTGAATGTATGTTCACAGACTGAAGAACAGCGAGTGCCTTATGGATGAAGGTAATGGACGTTTTACAGAGGTCACCTTAGACCGAGTCGCTTTAGAGATGACGCCTCCCCCAATCACTATGACAACAACCACGGACGCCAGCGAGAGAGATGTGGAGATGGAGTCCAGTGAG[G/A]TTGGTGTCTGTATTACCTTGCCCATTATACTCAAGTGTTACATAATCCATATGTGTTGTGAAGCGTGAAGTTACATTGGCCTGAATCCACAACAATGCACTGGTGTTTCGATAACCTCTTGCTCTTCAATCTCATTTTTCCCTCTATTTCAGACTCTCACAGCCGAGCAATCTGTGCCTCTGAAGAGACGAGGTCGCAAAAGGCAACTGATTTTCGCCGACCAAAACACACAGATTTCCCAGGATGCAATGCGACAACAAATCAACAACCCTCTGACTGAAACTCAATCTCTGGTGGGAGGCCTGTGATAGATAATCTAATCACTAATGCTGGGAATCCTTTGACAACTCCTGATTTGATTCTATGAAGGTTCAGGGAATCAGGGTGTAATTACAAAAACAATTCTTGATTCTTCTCAATTGTCAAATAACAGCATGAGACACAAATCTTTTATCAACCAAAAGCAAAATCTAAATATTAATCTGGTAACTAAATTATCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45821
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100644 Nonsense 500 564 16 18
Genomic Location (Zv9):
Chromosome 24 (position 12632857)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 12584594
GRCz11 24 12730888
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGATCTGCCCCTGGGAGAGGCGGAGCTTGAGATGAGTGACATCATCACC[G/T]AGGACTTATTCAGGTGAATTGAGGCCAAGCAGATGTAAAAGCATATCAGA
Long Flanking Sequence:
CTTCATCCAGTATGTGATCCACAATATCTTAACACGCATTCAAATCCTGTTTGAACTAGTCCACATGAGTTGTATCAATCACTATACTTTAATATTGTACATATGCATCTGCCGTCACAGGTGTAGCCTTCTCTCTCTCTTTGACACACTAGCACAATCTGCATTATTTCCAACGTTGTCAAATAGCGACCAATTAACATAGACATAGGCTTTAATGGTAAACAATGTTACTTTGCAGGGAAACAATAAAAAAAATGCCTTAATATGTGTGATTTTTAATACCATTTTAGTTGCACAAATCTGATTTTTTAGCGAAATCCCAGAAGGACTGACAAAAATACTGTTGGTGAAATTTAGTCTCGAATCCTGTGAAATAAATGTTGTGTATGTACTGTAGGTCTCCGATTGAAGAGGCTCCTGTTTCTATGGAGGTTATATTAGAAGAGCACGTTGATCTGCCCCTGGGAGAGGCGGAGCTTGAGATGAGTGACATCATCACC[G/T]AGGACTTATTCAGGTGAATTGAGGCCAAGCAGATGTAAAAGCATATCAGAGATCTACAAAACAGGTTGTGCATGCCTAAGGGGCAGGGATTTCACTATTAACTTTCTCCAACTTAAAGTGTGTTTATTAAATGCTGTTTCTTACTTGTAGTTCAATATGTCTTAAATAAAATGTAAGCTTCAGGCTAGTGTTGGGTTTAGTGGTATTTGTATATTCTGAAACCAAAACACCACAATTTTGCCACACACTGTAAAAATAATACATGTCATGTTAAAGAGATGGTTTACCCAAAAATAAAAATTCTCTCATTTTCTCTCCCTCCACTTATTCTAAACTTATTTAGTGTTTTTTTTTCTTTTGTTCTGTTGAAGGCACTATTATGACATCTTGTTGCCAACATTCTTCAAAAGAAATTCAGACATGTTTGGAACAACTCAAGTGAGAGTGAACTTTCATTTTTGTATGAACTGTTCATTTAATCGTCAATCAGAGTACCGTCA
Associated Phenotype:
Not determined