Busch Lab

ZMP

hspg2

Ensembl ID:
ENSDARG00000076564
ZFIN ID:
ZDB-GENE-080807-4
Description:
Heparan sulfate proteoglycan 2 [Source:UniProtKB/TrEMBL;Acc:B2RZI0]
Human Orthologue:
HSPG2
Human Description:
heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:5273]
Mouse Orthologue:
Hspg2
Mouse Description:
perlecan (heparan sulfate proteoglycan 2) Gene [Source:MGI Symbol;Acc:MGI:96257]

Alleles

There are 12 alleles of this gene:

Allele Name Consequence Status Availability
sa24350 Essential Splice Site Available for shipment Available now
sa24349 Essential Splice Site Available for shipment Available now
sa29941 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa39410 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13580 Essential Splice Site Available for shipment Available now
sa15637 Essential Splice Site Available for shipment Available now
sa417 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa24350
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Essential Splice Site 866 3422 20 81
ENSDART00000112124 Essential Splice Site 866 3397 20 77
Genomic Location (Zv9):
Chromosome 23 (position 26870634)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26703456
GRCz11 23 26629997
KASP Assay ID:
2261-7852.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATGGGAGTGACTAAACAGTGTGCCAGTTCAACCTGGAGCAGAGATCAG[G/A]TAACAGAAAAACGTCCAAATCACTTACATTTTCAGTTATGTCAATTTAAT
Long Flanking Sequence:
AAAAGTACTTTTAGTTCACCTTACTTTGTTATAATGACCTTGTTTGGTGAAGATGCTTAATCTATTTCTTCTCATTAAAGTAAAATACTATTGTCCTGCTTAAGTTGATGAAAAGAAAGTCATTAAAAAATTATATTATTATTATAATTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAGTAATTAAGTAAAACCAGTATTACATCATTAGCGCACTATATGTTTACTAAGTGTTTTTATTATAGTATTAAATGACCATGTTGTTTTTAGCAGCTTGTAAAAGTATTGTTAAAGCCCTGCTTGATTTTTTCTGTTCCAGTCCAATGTAGCTGGTGCGCTGTGTGACGAGTGTAAGACTGGTGCTTTTCATCTGACGGCTGATAATCCTGAAGGCTGCTTGCAGTGTTTCTGTATGGGAGTGACTAAACAGTGTGCCAGTTCAACCTGGAGCAGAGATCAG[G/A]TAACAGAAAAACGTCCAAATCACTTACATTTTCAGTTATGTCAATTTAATTTAAGGAATTGTTATGACTTTGCTTTTAACTCTTTAAAGTTACAAAAACATGAACTCACAGCATAAATGGTCTCATACATTTACTGTTAAAATGAATCTGTAAAATTTACGAAAAATAAGCAGCATTTGTGGTTGCCATAAAATAACGTAAAAATGCTGTTACCGTTAAAAATACGGTAGACATCATTTTTTGTTATTTATACTGTATGCATGTAACCATAAAATACATACGCCATTGTTTTGAAGTACGAACATCTACACGTACGTTTTGTTACACAGACAAAAATACAATTAATGATATGTTAATGACAAGTTTCACAAACTAATTTTAAGAGGAGCGTGTGATATGATTGACTGCAGCTAGTCACCCATCTATAATCATTAGTTATCCAATTAGATTAATTCAAACTCACTATAAATAGCCTAGCTAGAACTAATCCCTTACCTTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24349
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Essential Splice Site 1140 3422 26 81
ENSDART00000112124 Essential Splice Site 1140 3397 26 77
Genomic Location (Zv9):
Chromosome 23 (position 26862309)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26695131
GRCz11 23 26621672
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACCCACAGGCTTGTCGACCCTGTCCATGTCTGGGACAAACCAGTAACCA[G/A]TGAGTTATCCTTATTCTTAATCAAAAGTATTATGAAGAGTTTACCTTTTG
Long Flanking Sequence:
CCACATAAACCAATTAGCCATTTAATAATGATTGATGGACTTGCTGAGCATTGTGAAAATCATTCATTATAATAAGTCCACTGTTGCATGCCTGATTGACTAGTTGTCTACCATGAACAAAATGATAATAATAAAATCAATTCAAGTCAACCCTAATCTATTAATCTCTTATTGGATAAGAAGTTGACATGAAATAGTAAATTGATGCCTTAATAACAAATCAACCTTTTTTAATCAAGTAATCCTTTTTTTTTGTATCTAGTGAACTAGTCAAGAATCTAAAAAAAAAATTCATAATCTTGTCTAATGTCAAGTAATTAGTAAGTCGACCCATGTCTAGTCTGGAGTTCTTCATCATCTTTTCTTTTGTTTTAGAATTGCCTGCACAACACAATCGGACGCCGTTGCGAAAATTGTATCTCTGGATACTATGGAAATCCAAAGACTGGCGACCCACAGGCTTGTCGACCCTGTCCATGTCTGGGACAAACCAGTAACCA[G/A]TGAGTTATCCTTATTCTTAATCAAAAGTATTATGAAGAGTTTACCTTTTGGACATAACAAATAATTCATCTGATCTAATACTCTTTGTCTGTCAAAGGCCTTCATCTTGTTACTTGGGCTCTGATGGACAGCCTGTATGTGAATGTCCTGCTGGTTATACTGGAAGGCGCTGTGAAAGGTATGTTTCTATTGTCTTATTAGAGGGTAAATCTCTCATTTAGTTTGCTTGTAATGCTGGGCTCTTCAAACTGGTGATGGAGGTGATCAGGATCTCTTTATTTACTGCCAGAAAGCATGTTGCTTTGCAGCATCTCTTCAGCCATTTGTGATTGAATGGCGTTTTTCTGGTGGTATGGGAGAAGCGAGTCTTGAATCAGTGCCACCCATATCAAAGTGTCAATGTCTGTCTGAAGTGCCTTTTTGGAGGAGTTTGTAAGTGGAAGCTGTAGCGCTTGAAGTATTCATGTACGTTATGTCTGAAATCTGTACCGATTTCATGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29941
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Essential Splice Site 1322 3422 31 81
ENSDART00000112124 Essential Splice Site 1322 3397 31 77
Genomic Location (Zv9):
Chromosome 23 (position 26855228)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26688050
GRCz11 23 26614591
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACAGGAGCCTCATTATTGGCAGTTACCCAAGGCCTATCAAGGAGACAAG[G/A]TTGAGATTGACAATTTTTTGCATTTTATTGTTCCTACACTTTGCAAAACA
Long Flanking Sequence:
GAGTCTGTCGTTGCAAGGTAAAAAAAAAATCATGTTGTGTACATCTCAATTATAGAAACCATTTTAAAGCAAACTTTTTTTGTACTTAGATGAACGTTGAGGGTCCAACATGTTCCTCCTGCAAGCAAGGAACCTTCCACCTTAGTCCAGCTAACAAAGATGGCTGTCTGTCCTGCTTTTGCATGGGCGTCACTCAACAGTGCACCAGCTCCCGTCACTACAGGGATGTGGTAAGGCCTGATCAACTACACCAGGGTTTTTCATCAGGCGTATTTGCATGTGTTCATTTCCTGTCCCTTTTCCTTCAGGTTTCCACCATGTTTTCCCCTGGAAACTACCAAGGTTTTGCTCTTGTAAACCGCCAGCGCACAAACCGCATTGACAATGGCTTTTCTGTAGAGCTGTCCACTGAGGGGACACAACTCTCCTACACCAACTTCAACTATCTCGGACAGGAGCCTCATTATTGGCAGTTACCCAAGGCCTATCAAGGAGACAAG[G/A]TTGAGATTGACAATTTTTTGCATTTTATTGTTCCTACACTTTGCAAAACATACTTTCATACTTAGAATTTTTGTATAAATTCAAGTCTAAATATCTAAAAATTAAAAAAAATTACAAGCATTTTCTAGATGGGTAATATATAATGTTTTTTTCCTTCAGAAATTATAAATCAAAATGATAAAAATAATCTTGTTTTTGGTTTGAAATAAGATTATTTCACAACCCATTGCCATCTTATTTTTATTTATTAATTCATTTTCCTTCGGCTTAGTCCCTTTGTTCATCAGGAGTCGCCACAGCAGAATGAACCACCAACTATTCCAGCATATGATTTACATAGCAGATGCTCTTCCAGCCTCAACCCAGTACTCAGAAACAACTGTACACTCTCGCAAGCACACGTTCACTCATACACTAAGGCCACTTTACTCATAGCTTTACCTTTGTTCACGTGGGCTTTCTCTGGGTGGTCCGGTTTACCCCCACAGTCCACAGGAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39410
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Essential Splice Site 2149 3422 54 81
ENSDART00000112124 Essential Splice Site 2140 3397 50 77
Genomic Location (Zv9):
Chromosome 23 (position 26814178)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26647000
GRCz11 23 26573541
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAACTTGTACGGAATGACTCATAGCATCGTGTCACTCATTGTGAGAGG[T/C]AGAGCAACATTAAATGCGACATTTTTTGAAAAACTGGTTTTGTGAATTGT
Long Flanking Sequence:
TTTAGAAGGGCTCGAGTGTCCACTTACGTGGAAAGCACATTTTAGCTCTTTAGTGCAAGCCTCGCGTTTTAACCGGCTGCTGCACCTCGCATTTTTAATATATAATATATAATATATAAAAAAATCATAATATATAAAAAAATCTGCTTTTTGTTAATGTGACATGTTTCTGTCCGATATTACAAGATCCATGCATACTGCCACTATAAATAAAAGTTGTGTTTTGAAGGATTTGACATGTGGCCCTTTACTTGGTTTGCAAAACTTGATGCGGCCCTCGGGTCTGAAAGGTTTGCCCACCACTGTGTTAGAACATGTCAAAATCTCCATATGTGATATGTCCTTATGAACTTCTCTTCTTTAGATAATGTAAAGGTGGGTCCTGACAGTTCAATCATGACTGTTACAAATGCCCAGGCGAAAAACCAAGGCACCTACCGCTGTGTGGCCAGCAACTTGTACGGAATGACTCATAGCATCGTGTCACTCATTGTGAGAGG[T/C]AGAGCAACATTAAATGCGACATTTTTTGAAAAACTGGTTTTGTGAATTGTATTATTGCCTTCACACTTAGCACATACTATTTCTGCTTGAGATTTTCCTTACATTTATTATCATTGTTCAGGCATAATGCTCATTTCTCTCTCTTTTTTTTTCTTATTTCATTGGTAGAATCTCCTAAGGCTGTGGTGACCCCTGCAGGACCAGTGCGAGTCAGGGTCGGTGATCCCATTAATCTTGAATGCCAGGCCGCTGGAGAGCCAAGACCCTCAGTCAGATGGCACAGACTGGACAACAATCGCAAGACAATGCTGAGCAGCACCGTGCCTGTTGACTCCAGTGCTATCATACAGGTTATGAATCATTTGTTGTATTGATGATGTTGATTTCCTGATTGTTTGGCCTTTATGTTCATCAGAAAGGTTTTATACTTTGTTTACAGTGAAGAGAAAAATTAGAGAGCAGTTCAAAACACCTTTTTTGTTTGTTTTTTTATTATGTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13580
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Essential Splice Site 3228 3422 75 81
ENSDART00000112124 Essential Splice Site 3203 3397 71 77
ENSDART00000111029 Essential Splice Site 3228 3422 75 81
ENSDART00000112124 Essential Splice Site 3203 3397 71 77
Genomic Location (Zv9):
Chromosome 23 (position 26794634)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26627456
GRCz11 23 26553997
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCAGCTTCAGCGAGGCCATGTGGAGTTTGGAGGGTAGTGGGGGAAATGG[T/C]ACAGTATGAATTACAGTCTGCCTGACTCGCTCGTCACTAACMAGAGGAGA
Long Flanking Sequence:
TTAAAAGGTCTTAAAAAGTCTTAAATGTGTTACTTTTAGTTAACAATAATGTCCGCTCTATACTTCTGTTTTACATTTAAATAATCTTAAATTACATCATTTCAGAAGTATGGAGACAAACACACAGCTACCTAAACCCAATATTCCTACAAAAATGAATTTTAACTGCCTTATTATCCCTAATACTAATATATTGGTCCCAGTTTGCCTCATTTATCATTTTCCAGAATTCACTCTCTCTCTCTAAGGAAATAAAAGCATTTTTCTGTAGTTCCATTGCATTGTACCGAACCGCAGCTGTAAGTGATTCATCATAAAGCACCATACTGTAGGGAACTAACTATCCGTTCTCTATAACCCGCCATGGCTTCATCGGTAGCGTTTTAGCGGGTGAAAGAGGACACGTGTGACTGAATCTCACCGCTGTATCCCACACACACAGGGCAGGAGTCCAGCTTCAGCGAGGCCATGTGGAGTTTGGAGGGTAGTGGGGGAAATGG[T/C]ACAGTATGAATTACAGTCTGCCTGACTCGCTCGTCACTAACAAGAGGAGAACATCTTCCTCCTCCTCAGGGCCCCGCAGCCCGCCTAACACCCACCGATACAAACTACTGCTGTGCCAAAATGCTGAAGAAGAAAACAGGAAGACGTGCATTTCAGGGGTCTGTTTACTGAGCTTTTATTAGCAAAAGCAAACTAATATTTATTTATCGTTGTTGATTAAATATAATTTGTAAGAGATCTTGATTATGAATGTATCTTAATGAAAGTTACTCAACATCTTTATAGCAAGATTTTGCTTCTGGGAAAAGAACGGACATTATTTTCAGACATTATTGACAAATAGTTTTGTTTGTTTGTTTTAAGCTTTAAATTTCAACGAATTGTGCTTAATTTTATTTTTTTGACAATTATATTTATAACTTTATTAAATAAACCTAAATTTACAATATATTTTTGTTATCTACACTTTAAAAAATGTAACTAGATTTTTTTGACAATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15637
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Essential Splice Site 3228 3422 75 81
ENSDART00000112124 Essential Splice Site 3203 3397 71 77
ENSDART00000111029 Essential Splice Site 3228 3422 75 81
ENSDART00000112124 Essential Splice Site 3203 3397 71 77
Genomic Location (Zv9):
Chromosome 23 (position 26794634)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26627456
GRCz11 23 26553997
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCAGCTTCAGCGAGGCCATGTGGAGTTTGGAGGGTAGTGGGGGAAATGG[T/C]ACAGTATGAATTACAGTCTGCCTGACTCGCTCGTCACTAACMAGAGGAGA
Long Flanking Sequence:
TTAAAAGGTCTTAAAAAGTCTTAAATGTGTTACTTTTAGTTAACAATAATGTCCGCTCTATACTTCTGTTTTACATTTAAATAATCTTAAATTACATCATTTCAGAAGTATGGAGACAAACACACAGCTACCTAAACCCAATATTCCTACAAAAATGAATTTTAACTGCCTTATTATCCCTAATACTAATATATTGGTCCCAGTTTGCCTCATTTATCATTTTCCAGAATTCACTCTCTCTCTCTAAGGAAATAAAAGCATTTTTCTGTAGTTCCATTGCATTGTACCGAACCGCAGCTGTAAGTGATTCATCATAAAGCACCATACTGTAGGGAACTAACTATCCGTTCTCTATAACCCGCCATGGCTTCATCGGTAGCGTTTTAGCGGGTGAAAGAGGACACGTGTGACTGAATCTCACCGCTGTATCCCACACACACAGGGCAGGAGTCCAGCTTCAGCGAGGCCATGTGGAGTTTGGAGGGTAGTGGGGGAAATGG[T/C]ACAGTATGAATTACAGTCTGCCTGACTCGCTCGTCACTAACAAGAGGAGAACATCTTCCTCCTCCTCAGGGCCCCGCAGCCCGCCTAACACCCACCGATACAAACTACTGCTGTGCCAAAATGCTGAAGAAGAAAACAGGAAGACGTGCATTTCAGGGGTCTGTTTACTGAGCTTTTATTAGCAAAAGCAAACTAATATTTATTTATCGTTGTTGATTAAATATAATTTGTAAGAGATCTTGATTATGAATGTATCTTAATGAAAGTTACTCAACATCTTTATAGCAAGATTTTGCTTCTGGGAAAAGAACGGACATTATTTTCAGACATTATTGACAAATAGTTTTGTTTGTTTGTTTTAAGCTTTAAATTTCAACGAATTGTGCTTAATTTTATTTTTTTGACAATTATATTTATAACTTTATTAAATAAACCTAAATTTACAATATATTTTTGTTATCTACACTTTAAAAAATGTAACTAGATTTTTTTGACAATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa417
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111029 Nonsense 3276 3422 77 81
ENSDART00000112124 Nonsense 3251 3397 73 77
Genomic Location (Zv9):
Chromosome 23 (position 26789073)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 26621895
GRCz11 23 26548436
KASP Assay ID:
554-0277.1 (used for ordering genotyping assays)
KASP Sequence:
ACCATTGAGTTAGAGATCAACACTGCCTCAAAGGACGGCCTCATCCTGTG[G/A]CAGGGAGTGGTATGTTTGTACAAATGTGCGCCCTTGTCTTCCCATGACAC
Long Flanking Sequence:
GGTATGTGTAATATCATTATGCCTGCTTCAGCTATATCAGGCTACGAAATGGCAGCTTTTTCAAAATCTGTCAGTCTTAGTACAGGATGTAATTAAAAAAGAGCCAAACTATAAATAGGAACATTATCAAGACTCCTGTTTTGAACATTTTTTTTGGTTTGTTTTTGTTTTTTGAGTGAGACGCTAATGGTCTAATCTGATTCAATTATTAATGTTATGATAAGCTAATCTAAAAATGCTCCCACCAGATCCATAGATGGACTAATTGGATTCAAAAATGGTCAAACTCCAGGGGACTTGTAAAATGAGCCTATTTCCAATAAAGTAGAGTGTTCCTTTAATTGAACTTAAATGGATGCTGTCAAGTTTAACAATAAAATATGTGTTTGGATATTTTCTGGTTGCATTAATGACTGTTTGACTTGTTGCAGTGCTCCTGACTCTCCAGAGACCATTGAGTTAGAGATCAACACTGCCTCAAAGGACGGCCTCATCCTGTG[G/A]CAGGGAGTGGTATGTTTGTACAAATGTGCGCCCTTGTCTTCCCATGACACACACATTTAGAGTCCAAGATATAAATTTTTAGGCACAAATATGTCTGTACAGTATACTGTAAAATGTCCTGTTCAGTGCATATCTTTTAAATCTGCTTATAAATGTTTATTTTGGACACTACATATACTCTCGCATTATGATCATGGGTAACTGATATGGAACTGACATGTTTTACATTTCATATTCAGCCTCAATTTACTAAACTGAGTCAAATGAGTTTGCTTGGAGCTGGATTGTTGATCGATATGCATTTGTTCCTCACACTCACCCTTTTTTTTTGGCTGCACTGCATGTTTGCCTGCCTAACTCACCTTCATCCTCCTCAGGAGTCTGCAGGTGCTCTAAACCTCCATAAGAAGCATGCTAATATAAAGGTATTCACTCTTCACAAGCAGAAAACGATGGAAAACACAAAATTATGTCTGCATTAGCATGATCATATCATTATC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461