ZMP

eef2a.1

Ensembl ID:

ENSDARG00000042094

ZFIN ID:

ZDB-GENE-050522-500

Description:

eukaryotic translation elongation factor 2a, tandem duplicate 1 [Source:RefSeq peptide;Acc:NP_00103

Human Orthologue:

EEF2

Human Description:

eukaryotic translation elongation factor 2 [Source:HGNC Symbol;Acc:3214]

Mouse Orthologue:

Eef2

Mouse Description:

eukaryotic translation elongation factor 2 Gene [Source:MGI Symbol;Acc:MGI:95288]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa29761	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa29762	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa29761

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000024751	Essential Splice Site	204	854	None	13
ENSDART00000110200	Essential Splice Site	None	160	None	15
ENSDART00000143641	Essential Splice Site	204	854	None	13

Genomic Location (Zv9):

Chromosome 22 (position 20457353)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	22	20114046
GRCz11	22	20139024

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CATCTCCACCTATGCTGAGGATGAGAAAGGCCCTATGGGCAATGTCATGG[T/C]GAGTGCCTCAAGGCTCCGTCATGGGTCCATTAATGCTTTCTGTTTTATCT

Long Flanking Sequence:

GAGTGCAAAGATGGCTCCGGCTTCCTCCTCAACCTGATTGACTCCCCTGGGCATGTTGACTTTTCTTCAGAAGTTACAGCTGCACTGCGTATCACAGATGGAGCATTGCTGGTGGTGGATTGTGTGTCTGGTATGTGCAGAAATAGTTTTTTTGTTTGTTTTTCCCAAATGACCGTTTTATTAATCAAAGACTTCCTTGGTATAATTTGATTTGCATGCTTTACTTTGATTCTGTAACTAAATCTATAGTTTTTTGGGCCGCTTATAAAAATGTCATTGTTTGGCAGGTGTGTGCTTACAGACAGAGACTGTGCTCAGACAGGCCATTGGTGAGAGGATTAAACCAGTTTTGATGATTAACAAAATGGATCGAGCTTTGCTCGAGCTACAGTTGGTCCCTGAAGAGCTGTACCAGATCTTTCAGCGCATTGTTGAGAAAGTCAACGTGACCATCTCCACCTATGCTGAGGATGAGAAAGGCCCTATGGGCAATGTCATGG[T/C]GAGTGCCTCAAGGCTCCGTCATGGGTCCATTAATGCTTTCTGTTTTATCTCTGGGCTTATTTCTAATATTCATTGTGAATGTTTTTAACATCCTGATCTTAGATTGATCCTGTCATTGGTAATCTTGCCTTTGGATCTGGACTGCATGGATGGGCCTTCACTTTGAAGCAGTTTGCTGAGCTCTATGTGAAAAAGTTCGCTGGTAAAGCTCAGCTGGGACCGGAAGAGTACATCAAGAAGGTGGAGGACATGATAAAGAGACTTTGGGGCGACAGGTGAGAGGATGTTCCAACACAACTGAATGAATGTAATGTTGCATTTCTGTACGTGACATTTTATGTCCATTTGTTTGCAGCTACTTTGACTCTACTACTGGCAAGTTCAGCGAGTCTGCGACATCGCCAGATGGCAAGAAGCTTCCCAGGACTTTTGTTCACTTAGTCCTGGACCCCATCTTCAAAGTGAGGAAACTAGCAACAATTCTGTTTTTAATGCAAGCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa29762

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000024751	Nonsense	637	854	10	13
ENSDART00000110200	None	None	160	12	15
ENSDART00000143641	Nonsense	637	854	10	13

Genomic Location (Zv9):

Chromosome 22 (position 20459413)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	22	20116106
GRCz11	22	20141084

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACTGCCAGCCAGGAGATGAATGCCCGTGCCCAATACCTTGCTGAAAACTA[T/A]AAGTGGGAAGTGACTGAAGCTCGTAAGATCTGGTGCTTTGGCCCTGAGGG

Long Flanking Sequence:

TGAAGTTTAGTGTCAGTCCTGTGGTGAGAGTGTCCGTGGAGGTCATGGACCCTGCTGACCTTCCTAAACTGGTGGAGGGATTGAAGCATCTGGCCAAGTCAGATCCCATGTTGCAATGCATCATTGAGGATACTGGTGAACATATCATTGCTGGAGCTGGTGAGCTTCACTTGGAGATTTGCCTTAAGGATCTTGAAGAGGACCATGCCTGCATTCCCCTCAAGGTACCAATAGCTAGTCCAATCGGCAACACATTATACCAACTATGATTGTTCTCTAACATGCTGTTCTTTACAGAAATCAGATCCATTTGCTTCCTACAGAGAGACGGTCAGTGATGGCTCCAAACAATTGTGCCTTGCCAAGACGCCAAACAAGCACAGTCGTCTCTTCATGAAGGCCTGTCCTCTGGCTGATGGTCTTGCAGAAGATATTGATAAGGGTCGGGTCACTGCCAGCCAGGAGATGAATGCCCGTGCCCAATACCTTGCTGAAAACTA[T/A]AAGTGGGAAGTGACTGAAGCTCGTAAGATCTGGTGCTTTGGCCCTGAGGGAACTGGACCCAACATCTTGGTAGATTTGACCAAGAGAGTGCAATACTTGAATGAGATTAAGGACAGTGTGATTGCTGGATTTCAGTGGGCCACTAGAGAGGTATGATAAAAGCACAACATTTATTCATTGTATTATAACTCTAATGTAAGACAGTTTTACCTTTCTTTATAATCTAGAGTGTCCTTTGGATTCTCTAAGGTGAACGCCACCTTGATAAATTTTGCATCTTTACACCTTTCTGGGATTTTCTAAATTGCAAAGACTAATTTGGTTATGTTCAATTGGATTAAGATGTCCCTCTATAATCAACTAGACACCTTTTGCTTTAGTTTGAGTCACTGCTCTGTTTTATTTAATCGTTTTGTGCTTTCTAGGGAGTCTTGTGCGCAGAGAACATGCGTGGCATTCGCTTTGACATTCATGATGCAACTTTGACTTCTACTGCCATT

Associated Phenotype:

Not determined