Busch Lab

ZMP

ppp3ca

Ensembl ID:
ENSDARG00000004988
ZFIN IDs:
ZDB-GENE-050417-406, ZDB-GENE-091113-24
Description:
protein phosphatase 3, catalytic subunit, alpha isozyme [Source:RefSeq peptide;Acc:NP_001185479]
Human Orthologues:
PPP3CA, PPP3CB
Human Descriptions:
protein phosphatase 3, catalytic subunit, alpha isozyme [Source:HGNC Symbol;Acc:9314]
protein phosphatase 3, catalytic subunit, beta isozyme [Source:HGNC Symbol;Acc:9315]
Mouse Orthologues:
Ppp3ca, Ppp3cb
Mouse Descriptions:
protein phosphatase 3, catalytic subunit, alpha isoform Gene [Source:MGI Symbol;Acc:MGI:107164]
protein phosphatase 3, catalytic subunit, beta isoform Gene [Source:MGI Symbol;Acc:MGI:107163]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa29618 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa23963 Nonsense Available for shipment Available now
sa44970 Nonsense Mutation detected in F1 DNA Not yet available
sa37336 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa29618
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005929 Essential Splice Site 19 521 2 14
ENSDART00000144331 Essential Splice Site 19 505 2 13
Genomic Location (Zv9):
Chromosome 21 (position 28401737)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 28970648
GRCz11 21 29007343
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGACTATGACACACAAGTTCTGATCTATTGTTTGCGTTCTTGCTCCTCTC[A/T]GCCGTTCCCTTCCCCCTGAGCCACCGCCTCACCATGAAGGAGGTGTTTGA
Long Flanking Sequence:
GTACCCAAGTGTCACGAGTGACAGAATGTTGTGGGACTGCTGTACAATAGTTATTATTAGGGACTATAAATAGCAGAATTTAGCGGTTTTATTTTAGCGGATTTTTTAAAAGCATGACGGGAAAACACCTACACAGTTATGAATGTATTAAAACTTGTGCTTGTTTGTTGTAAAATTCGTAATAATTACAAAAATACTAATTTGTGGATCTCCTTCTACTTCTGGGTGCCGCTACACTGCCGTTGTGGCTGGTGTATTCTGGGAAAATTTCTTACCCAAATTCAGAAACAAAACTTCTAAATTTCTAAAGGATATAGTTACAGAATTGTTTCCCTGGTGAAGAGATGCCAATTTAACATTGTATTAACCAATTTAACACTGTAGTACAATTCAAGGTTTTATGTTTTAAAAGGCATAACTGTATGCAACATAATTTAGTTTCATCAAAGCTGACTATGACACACAAGTTCTGATCTATTGTTTGCGTTCTTGCTCCTCTC[A/T]GCCGTTCCCTTCCCCCTGAGCCACCGCCTCACCATGAAGGAGGTGTTTGACTGTGAGGGGAAGCCGAGAGTGGATCTCCTGAAAGCCCACCTCACTAAAGAGGGCAGAGTGGAGGAGACCGTGGCCCTGCGAATCATCAATGAAGGGGCTTCTATCCTACGCCAGGAGAAGACCATGCTGGACATAGAGGCACCTGTCACAGGTAAAACGTTTTGTATTCCTTAATTACCTTCACTATGTTAAAGGGATAGTACATTTAAAAAAGAAAACACACTATAAAGTTGAAGGCAAAATTATTACAGCTGCTTTGAATTTTTTTCTTTTACAAATATTTCCCAATTGATGTTTAACAAAGTTTAATAATTCTTACGTCAACTGTATATTTACCCTTCTTCGATAAAACTGGAACCATATTTGTGCAGGCCATGTATACATTGCACCTAAATTTGGTTGTCAGTTCAACCTTCAGAGGCTTAGAGCATCTTAGTTGCCAGATCTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23963
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005929 Nonsense 111 521 3 14
ENSDART00000144331 Nonsense 111 505 3 13
Genomic Location (Zv9):
Chromosome 21 (position 28433615)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 29002526
GRCz11 21 29039221
KASP Assay ID:
2261-5758.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTTTGACCTGATGAAGCTGTTCGAGGTCGGTGGATCTCCAGCCACGACA[C/T]GATACCTCTTCCTGGGAGATTATGTGGACCGGGGCTACTTCAGTATCGAG
Long Flanking Sequence:
GTTAAAAACCCAGAGATATGGCAGCTACTGTAGCTCTCAAGTGTACTTTATTAAATATTCTTTTACTAACGCGTACTTTAAATTATGGAATAGCGATTCCCATACCAGTCCATTTATGGACATCCCTTAATCCCTTACTTACATTTTCAGAAATAAACCTGGCCTTTTCAGAAGGTGCCTTTTGTATTTTTTTAGTTAGAATAAATAAATCATGCTTATATTTAGCTAATAAAATGCATTTTTAAAGACCCAAAATAAATCTTTTAGATACAAAATTGTTCCTTTTGAAAAGGAGTATCTGCTGACATTAAGGCATTATGATTTCAGTAGCTATTGTATGAATCAATAAGCGATTGAGATTTATGCAGTATATTAAACAAACATTTGTTCAGCTGGTCAATACTTTTTCTCCTTTGGTTTATGCAGTGTGTGGTGACATCCATGGGCAGTTCTTTGACCTGATGAAGCTGTTCGAGGTCGGTGGATCTCCAGCCACGACA[C/T]GATACCTCTTCCTGGGAGATTATGTGGACCGGGGCTACTTCAGTATCGAGGTGAGAGGAGCCCTTCTGCCTATTTTTAATCATGTTAATTGGAGGAATTAGTTCATGTGTATTTGTTTGAATGATAAGGTTTAGTTCAATCACCACCAGGTTTAGACTGAAGCAGCATTTAAGCAAAACCTGATGAATTGATGATTAAACCTTAAACCTGATTAGGTTAAAGAGAGTTTCTGCCTGGTAGACACATGTAACATATAATGTAATAAAAACCCATGTAGAATAAATAATGTAATAAATATATATTTTTTTATTTACATTTATTATTTTATTTAAAAAACAGTAACAAAGTTAAAAGCAAGCTAAATACTATAATACTGTTAAAATGCTTTAAAAAATTTTTAAAAAAAATAATATTTTGTGTGTGTGTGTGTGTATATATATATATATATATATATTTTTTTTTTTTTTATATATATATATATATATTTTTTATATATATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44970
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005929 Nonsense 283 521 7 14
ENSDART00000144331 Nonsense 283 505 7 13
Genomic Location (Zv9):
Chromosome 21 (position 28454274)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 29023185
GRCz11 21 29059880
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTTCCTACAGAATAATAACTTGTTATCAATCATTCGAGCGCACGAAGCA[C/T]AAGATGCAGGGTACGTTTTTGCAATCTGTCTTTGTAGCAATAAATACTCT
Long Flanking Sequence:
TATATAAATAGAAAGCATATTAAATGCAAGTAAAGTGTCTGCTTTATGTATAAAGTATTATTTGTGGAAAAAAAATTCGGCAAAAGATAAATGTATGTATTGATCAAACTGCATATTTATTCTATCATGTAAACATAGATTTTGTTATAAAGCTCTGATACGCTTTTATTATTTTAATGCTTAGAAAAAAATCTGTCTAAAAGACGTTTTGCTTTGTTTTTTGCTGTAGTGATAACATGTGATAACTACTGGACACATGTTGAACAGCACTAATGCTTCATTTACATTTGAATATTTTGCTTGGCTGACATTGGAAAGCACAAGGGGGAAAAACAATACAACATTAATGAGAGGCGTCCACCCACAGTTTCCGAATATTGGCTCATATTTTCTTTCTCATGCTCTTTTCCTTTTTTCCACCTCTGTTTTGCAGTTATCCGGCTGTCTGTGACTTCCTACAGAATAATAACTTGTTATCAATCATTCGAGCGCACGAAGCA[C/T]AAGATGCAGGGTACGTTTTTGCAATCTGTCTTTGTAGCAATAAATACTCTTCATTTTTATTTTTAAGGATATGTTTTGTCATATAGACACAATTTTGGAATATTTTCACTCTGAAAGTACGAAAGCGAAATTGTGTTTTGCTCTGAAAGTGTTTTTATCTTCTCTTCCTACAGGTACCGGATGTACAGGAAGAGTCAGACCACTGGCTTCCCTTCCCTAATTACCATCTTCTCTGCACCAAACTACCTTGATGTTTACAATAACAAAGGTGATTCTTCCTTTAACTTACTGTGAATGCGTTGTGATGGGAACAGAGAGGTGGATGCGAGCGTGGGCAGGACCCTCTATGGCAAGCTGTTTTAACATTTATACGCAGACAATGCTAGCATCAGGGGCGGATTTAACCAATAAGTGAGGTAAGTGGCTGCTTAGGGCCCCAAGAAATCTGGTGGCCTGCAATAAATGTCTAGAAGTATAAATTATACCTATAAACTATATAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37336
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005929 Essential Splice Site 386 521 11 14
ENSDART00000144331 Essential Splice Site 386 505 11 13
Genomic Location (Zv9):
Chromosome 21 (position 28460633)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 29029544
GRCz11 21 29066239
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTGGTCATCCAGAATGAGACTGCTTCATTTTTCTTTTTTCCGCCCACA[G/A]CAAATGCAGCAGCTGCTCGGAAAGAGGTGATTAGGAACAAGATCCGTGCT
Long Flanking Sequence:
GTCAAGCTGAATTCAGAAACAATGAGGGTTTTGTGTGAATGAATTTCATTTCACTAAACACTTTACACCCTTTTCAGCCTCATGAGGATTTACCATGGTTTTACTACAGTAGAAGTAGTAATATATTTTTGTCAAATTTGTCAGATTTACCACTTATTAAACTACAGTTTTGATTCAACAACCATGGATAAACTATGCAGCAACTTCTACAGCAACACCATGTTGAATTTGTAATTATAACAGTAACCATGTTTCGATATTTTAGTAAAACCATGGTCAATTTAAATAGGGCTTCTGTACAAAAAGTAGCTTTAGTCACACTACTGAAATGCGTGGTTTAGTTAGTACCGCCATTTCTAAAGTTCCTGTAGTTACTCTGCCGCCAACATAATTTCTTGTGTGTCTACCTCTCTGTACATACAAGAATAAAAGTTTCTGTGGGTTTTTAGCCTCTGGTCATCCAGAATGAGACTGCTTCATTTTTCTTTTTTCCGCCCACA[G/A]CAAATGCAGCAGCTGCTCGGAAAGAGGTGATTAGGAACAAGATCCGTGCTATTGGGAAAATGGCCAAGATGTTCTCCGTGCTCAGGTACAAATGGGGCTTCCTCTGGCTGAGTCATTCAGACTGCGGTCAGAAGAGCCTCATGCTTCACAAAGCACTCGGGCTTGTCAGATAGATGATAGATTGAGGACTGGTTTCTTAGGCATTAAACTGGGACACAAGAAAGCATTTAAATGTAGCATGTGGTATGGAAAGTATTTTAAAGGTTGTATGAAACACAAAATATTTTTATGTATAATATGGAGTTGTGGACTCTCAGTGGACGTCTGTGAGTGTAACACACACTAAAATGGTGCTAAATAGCACTAAAAGTGTGTCTTTGGCTTGTAATCATAGGGGAACCAATTTAAGTGCTAGATGGCACCTATAAAGAACTTGTTAACAGTAATGGTTCTTCTGCAGTTATTTGAGGTGGTTAAGGCGCTATATAGCACCATCTTTA
Associated Phenotype:
Not determined