ZMP
si:dkey-11e23.3
Ensembl ID:
ZFIN ID:
Description:
Novel transcript similar to vertebrate peroxisomal long-chain acyl-coA thioesterase [Source:UniProtK
Human Orthologues:
ACOT1, ACOT2, ACOT4, ACOT6
Human Descriptions:
acyl-CoA thioesterase 1 [Source:HGNC Symbol;Acc:33128]
acyl-CoA thioesterase 2 [Source:HGNC Symbol;Acc:18431]
acyl-CoA thioesterase 4 [Source:HGNC Symbol;Acc:19748]
acyl-CoA thioesterase 6 [Source:HGNC Symbol;Acc:33159]
acyl-CoA thioesterase 2 [Source:HGNC Symbol;Acc:18431]
acyl-CoA thioesterase 4 [Source:HGNC Symbol;Acc:19748]
acyl-CoA thioesterase 6 [Source:HGNC Symbol;Acc:33159]
Mouse Orthologues:
Acot1, Acot2, Acot3, Acot4, Acot5, Acot6
Mouse Descriptions:
acyl-CoA thioesterase 1 Gene [Source:MGI Symbol;Acc:MGI:1349396]
acyl-CoA thioesterase 2 Gene [Source:MGI Symbol;Acc:MGI:2159605]
acyl-CoA thioesterase 3 Gene [Source:MGI Symbol;Acc:MGI:2159619]
acyl-CoA thioesterase 4 Gene [Source:MGI Symbol;Acc:MGI:2159621]
acyl-CoA thioesterase 5 Gene [Source:MGI Symbol;Acc:MGI:2384969]
acyl-CoA thioesterase 6 Gene [Source:MGI Symbol;Acc:MGI:1921287]
acyl-CoA thioesterase 2 Gene [Source:MGI Symbol;Acc:MGI:2159605]
acyl-CoA thioesterase 3 Gene [Source:MGI Symbol;Acc:MGI:2159619]
acyl-CoA thioesterase 4 Gene [Source:MGI Symbol;Acc:MGI:2159621]
acyl-CoA thioesterase 5 Gene [Source:MGI Symbol;Acc:MGI:2384969]
acyl-CoA thioesterase 6 Gene [Source:MGI Symbol;Acc:MGI:1921287]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa25139 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa29377 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa37056 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa25139
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000062342 | Nonsense | 49 | 437 | 1 | 3 |
Genomic Location (Zv9):
Chromosome 20 (position 28982056)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 29053269 |
| GRCz11 | 20 | 28956148 |
KASP Assay ID:
554-7316.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTTATAAGTGCTCTTTTGAAGACCCAGTGCATGTGACGGTGAGCGGCT[T/G]AAATCCACATCAACGCGTGGACCTGCGCTCCAAAATCACGGATGAAGGTG
Long Flanking Sequence:
CGCTTGATTGACGGCCAGAGGTTGGACATGATGTCATTTCAATCCCCGTTATGGATGTTTTTCAACTGTGACACAACGTCGGAGGGACGCCTTTTCAACGGTCATCGGACGTTTAAATCTTTGTTGGATTTAACCAACCTGTGATTAGATCAAAATCACATGCAAATTTTAATGGTTCAAAGTCAACATAAATATAAAATACACATAAATATAAAATTGATCTTGTGACTTTGGAAATTTGATATGCGCTCCGAACCACTGATTCAAATCCAAAGATTCATATCGTTTCGATGCTTCAGGGAGCTCTTTGGAAAGCATCCATTACTTCAAAGCATATCGTGATCACAGAGACGACATGTATGCAACTCTAAAATGTGCTCTTAAGCCTTTTGCAAGAAATACTCTTGCAAAAATGCACTACAGTTCAGGAGTGAGCATCAGGCTTCTGCCCAGTTATAAGTGCTCTTTTGAAGACCCAGTGCATGTGACGGTGAGCGGCT[T/G]AAATCCACATCAACGCGTGGACCTGCGCTCCAAAATCACGGATGAAGGTGGACGTGATTTCAAGGCTTTAGCGACCTATCAGGCAGATGACAGTGGCCAAATTGACCTCAAGCGCGACTCTTCTCTTGGTGGGAGCTTTACCGGGGTTGAACCGATGGGTTTATACTGGGCTCTGAAAGCAGACACAATAAGCTGCAAGTTTAAACTTAAAGATGTGACGCGTCCAGCTCTTGTTGACATTGAAGTTGTCAGTGATGATAAAGTCCTGGCCAAAGTGACCAACGAGAGACACTGCCTGACCGATGGTGTCCGGAGAAGACCTTTAAATGAAGACAGGATCAGAGGAACTCTTTTTATGCCACCTGGTCAGTTATTTCAGTGTCTTTAAGAATAGTTTATAATTATTATCGCAGTATTATCGTCAACTTAGTGCACGTTCGTCTGCAAGACAGAGATCATTTTAACTATAAAACTGTTGTGCTGAAGGATCTGATAATTCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa29377
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000062342 | Essential Splice Site | 238 | 437 | 2 | 3 |
Genomic Location (Zv9):
Chromosome 20 (position 28973363)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 29044576 |
| GRCz11 | 20 | 28947455 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTTGAGTACTTTGAAGAAGGTATAGATTTCCTACGGCAACAGCCAGAGG[T/C]TAGTACAACCATTTATTATCTTTAGTTGTTGTTTTTATAGCAAAATTAAT
Long Flanking Sequence:
GACCAAAAACTGTGGCTTTACAATAACTTTTTTTCAGGGCACTATTTGAAAATATTGTGTCATTTGACAATAAAATGATCATGTACTGTATTTCATAACGATATCTCTGTATTTAATGGGTCTTTTTAACGGCTATTGGAAGTTCAAATGTTTGCTAGGATATGAGTGTTTGTGGCATTCCCTTGTTGTGCTGAAAATGGGGATGTGTAGTTTAAATTGACAAGCTATGCCTATCTAGACACAACCTAATGTTTTTTAAATATAGAGTTTATAATGCTGTTTTTATACTTTCTCAGGTAAAGGACCATTTCCTGGGATTTTGGATACATATATACTTAGAGGAGGTCATTTTGAGTTGAGAGCAGCTCTGCTGGCAAAGAGAGGTTTTGCTGTTTTAGCCTTGGCCTACCAAAATTACCAAGATTTACCCAAAAGTTCTGACAAATTTCACCTTGAGTACTTTGAAGAAGGTATAGATTTCCTACGGCAACAGCCAGAGG[T/C]TAGTACAACCATTTATTATCTTTAGTTGTTGTTTTTATAGCAAAATTAATTAAATTACTATAATGGGACATTTTTAAAAATCACAAAATTGATTTAATTATTTATTTATTTTAGGTGAAAGGTCAAAAAATTGGCCTATTGTCTATATCAAAGAGTGGAGATCTGGCTTTGTCCATGTCAACATTCCTGCCTGATATAGCAGCTACTGTTTGGATCAATGGATGCAATGCCAACAGTGTAGTCCCACTTTACTACAAAGATATGTATATTCCACCTCTGACACTTGACTTTAAGAAAAAAAAAATCACACCATTAGGCCTTGTGGATATGCTAGATGTTGTGAAAGACCCGATGTCCAAAGAAGGTCTTCCTAGTGTTATCCCCATTGAGCGTGCCCCTGGTAGATTCATGTTTATAGCATCAGAAGCCAACATGAATTGGCGAAGCGCCTATCATGCAAAATTAGCATGCGACAGACTCAAAGCTCATGGAAAAAAAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa37056
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000062342 | Nonsense | 384 | 437 | 3 | 3 |
Genomic Location (Zv9):
Chromosome 20 (position 28972811)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 29044024 |
| GRCz11 | 20 | 28946903 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATGAGCTGGTAAAGTATGAAAAGGCGGGTCATTTTATTGAGGTGCCCTA[T/A]ATGCCCTTTTGCTTTGCTAATTTTCATAGTGTACTTAAGCAACCTGTTTT
Long Flanking Sequence:
AAATTACTATAATGGGACATTTTTAAAAATCACAAAATTGATTTAATTATTTATTTATTTTAGGTGAAAGGTCAAAAAATTGGCCTATTGTCTATATCAAAGAGTGGAGATCTGGCTTTGTCCATGTCAACATTCCTGCCTGATATAGCAGCTACTGTTTGGATCAATGGATGCAATGCCAACAGTGTAGTCCCACTTTACTACAAAGATATGTATATTCCACCTCTGACACTTGACTTTAAGAAAAAAAAAATCACACCATTAGGCCTTGTGGATATGCTAGATGTTGTGAAAGACCCGATGTCCAAAGAAGGTCTTCCTAGTGTTATCCCCATTGAGCGTGCCCCTGGTAGATTCATGTTTATAGCATCAGAAGCCAACATGAATTGGCGAAGCGCCTATCATGCAAAATTAGCATGCGACAGACTCAAAGCTCATGGAAAAAAAAACTATGAGCTGGTAAAGTATGAAAAGGCGGGTCATTTTATTGAGGTGCCCTA[T/A]ATGCCCTTTTGCTTTGCTAATTTTCATAGTGTACTTAAGCAACCTGTTTTATTTGGTGGGGAACCTAAATGTCATTCAGAGGCACAGGTGGATGCCTGGCCGAGGATTATCAATTTCTTCAAAAAACACTTAGCAACTGCTGATTACAATCTCAGTCCTATGCTGGAAGAGAACATACATGAAATGTCACAGCAATGACATCCAATTATAAAAAGATTGCTTAATCTCATCAAATATAATGAGAAATAGTTTCTGCATATTTGAAAAATAGCATGAAAAAAATTGAAACTAAAATTATTTTAAAAAATGTTTGAAGTGTTATTTCACTGCTTCGCCACACTTTTGCATTATTAATTAGGTAGATTGTATGGGTGCCAAAGGTCCTGGATTTGGTTTCTCTGTCTTTTTTTATCTTTATTTTTGGCTTTCCTTATGAATGTTTCTAGCAAACTTTTTGAACTAGACGTGCAGTTAAAAGCATCAATAAGTAATTAATTACT
Associated Phenotype:
Not determined