ZMP

tbk1

Ensembl ID:

ENSDARG00000063708

ZFIN IDs:

ZDB-GENE-060512-359, ZDB-GENE-060512-359

Description:

serine/threonine-protein kinase TBK1 [Source:RefSeq peptide;Acc:NP_001038213]

Human Orthologue:

TBK1

Human Description:

TANK-binding kinase 1 [Source:HGNC Symbol;Acc:11584]

Mouse Orthologue:

Tbk1

Mouse Description:

TANK-binding kinase 1 Gene [Source:MGI Symbol;Acc:MGI:1929658]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa29267	Essential Splice Site, Missense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa29267

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site, Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075762	Essential Splice Site	307	365	8	9
ENSDART00000093347	Missense	308	727	7	20

Genomic Location (Zv9):

Chromosome 19 (position 46937986)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	128381
GRCz11	4	141032

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GTGCTGGGGGTTTGATCAGTTCTTCGCAGAGACCAGCGACATCTTACACC[G/T]CATCGTGGTCTACGTCTTCAGTCTGCAGCAGGCCACGCTGCACCACGTCT

Long Flanking Sequence:

GCGCTCTAGGCTAGTGTTTACAGCAGATGACGCTCTAGGCTAGTGTTTAACAGCAGATGGCGCTCTAGGCTAGTGTTTAACAGTAGATGGCGCTCTAGGCTAGTATATAATGGTACTTAATTGCTTAGTAATTATTCAATTGTCCAATAATTGATCAGTAATTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGCAGGTATAAGATCATCACAGAGAAGCCCCCCGGCGCCATCTCCGGACACCAGAAGTTTGAAAATGGGAAGATCGAGTGGAGCTCCGAGATGCCCATCTCCTGCAGCCTGTCCAAGTATGTGTGTGTGTGTGTGTGTGTCTGCGCAGCTCAACTGTGTGTGTGTGTCTGATTATGTGTGTGCGTATTCCAGGGGTCTGCAGAGCCTCCTGACGCCGGTGCTGGCGAATATCCTGGAAGCGGATCAGGAGAAGTGCTGGGGGTTTGATCAGTTCTTCGCAGAGACCAGCGACATCTTACACC[G/T]CATCGTGGTCTACGTCTTCAGTCTGCAGCAGGCCACGCTGCACCACGTCTACATACACACTTACAACACGTGAGCACACACACACACAGATCACACACAGATGAACATTCCTCACATTAGCTCAGTGTCCGTCCTCGGCTGATGTTTTCCTGCTGGGTGTGTGTTTTCCAGAGCGAACCTCTTCCAGGAGCTGCTGTTCAGACGCACCAACATCACTCCGTCCCATCAGGAGCTGCTCTACGAGGGCCGACGGCTCGTCCTCGACCCCAACCGGCAAGCACAAACCTTTCCCAAGACCTCCAGAGACAATCCCATCATGCTCCTGTGCAGAGACCCCGTCAACACCGTCGGCCTGCTGTTTGAGGACCGTGAGTCTGGCGCCGCTACTGTTGAAGAGATGATGCAGTTATTATTGTAGATCAGCTCAACAGTTATCATGTGTTAATAGCTGATCATAACCCTGCCCTGTGTGTCTGCAGCCAGCCCACCCAAAGTACAGC

Associated Phenotype:

Not determined