Busch Lab

ZMP

npr1a

Ensembl ID:
ENSDARG00000031751
ZFIN ID:
ZDB-GENE-060503-539
Description:
atrial natriuretic peptide receptor 1 [Source:RefSeq peptide;Acc:NP_001038402]
Human Orthologue:
NPR1
Human Description:
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [Source:HGN
Mouse Orthologue:
Npr1
Mouse Description:
natriuretic peptide receptor 1 Gene [Source:MGI Symbol;Acc:MGI:97371]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa15690 Nonsense Available for shipment Available now
sa29215 Nonsense Mutation detected in F1 DNA Not yet available
sa39249 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa10670 Nonsense Available for shipment Available now
sa44916 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa15690
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041298 Nonsense 277 1067 2 21
ENSDART00000136244 None None 672 None 17
Genomic Location (Zv9):
Chromosome 19 (position 26969451)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 26899563
GRCz11 19 26483786
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGCAAGTTGATGGTGGAGTTCTGGAGGCAGGGTTTTCCTCAGGAGGAGTA[C/A]GCTTTCTTCTTCATCGACCTGTTTGGACGCAGTTTGCAGAGCCATCCTGC
Long Flanking Sequence:
ATTGTCGTATTGGAATTCAGCACATCTTAATGCATAATAAATAGCACATTTTACCCCTGAAGCAGGCAAAAACATTGTACAGCAGTATAATCAATTACCTTCAGCAGTGACTCACAAAGCAGGAGCAGGAAATCCCATGTTTTACAGCCTAGGAAACACAAAAGCTTTGCTTCCATTTCAGCTCTTGGAGTGAGTTTCAGCTCGTCAACTTAATAACCTCCAGCCTAATTGGAAATTAAAGTGTCAGATGTTTTCAGGTGCTTTTGCATTTGCATTATATACCCAAGCTCATTCGCCACACAAGCACATTCCGTTCTAATAAGCGGGACTGAATTCTCATTAAGTCTGAACCGTTTTTTCTTCCATCCATGAGTACCCTTAAGGCAGATAATTGAGTTTGTTTATCTTGTGTTTGCAGTGGTGTATGTCTGCTGCAAGTGGGAGACGTTTCGCAAGTTGATGGTGGAGTTCTGGAGGCAGGGTTTTCCTCAGGAGGAGTA[C/A]GCTTTCTTCTTCATCGACCTGTTTGGACGCAGTTTGCAGAGCCATCCTGCCAGACCATGGGCAAGAGGAGATGCTGATGACAATGCAGCCAAAGAGGCCTTTAAAGTGAGTAATGTGCTGATGGAATAGTAATAATAACCAGATTGAGACTTTAGAGTCTACAGAGAGGGGTCTAGATCAATTTCAGATGTGGCCCAGATGTGTCTTTTTCTAAAACATATTTTGTTATAAATTTCTACAAAATATTCTTTAAAAATCTTTTAAATCTAATTTGCTAATAATGCTAATTATTAACATTATCAATCACCAGCTATTATTGTATTGTTCCAATCAGTGTTAAATATAGTTTTTCTGTTAAATATGCTTATGAAATTTAAAATTATATATTAAAAAAAGTGTTTATTTCAAATAGAATTATCGTTAATAATGCTTTACTATCACTTTTTTAGTTTGATGTGTTACTAAAAAGATCACACAAAAATTAAGACACAAACATACTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29215
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041298 Nonsense 505 1067 8 21
ENSDART00000136244 Nonsense 110 672 4 17
Genomic Location (Zv9):
Chromosome 19 (position 27066225)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 26996337
GRCz11 19 26580560
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCTTTGTCTCTCGGCGTGTTTCTCTGTCCGCCATCAGGAAGCTGAAGT[T/A]GGAGAATGAGTTGACCGCTCAGCTGTGGCGTGTGCACTGGGAGGACATCC
Long Flanking Sequence:
CTAAATCTTGGATATTTGACAAGACTGGTAGTGTATGTACAGTACAGACTGTTATATCGACTTTGCTGTGCTCTGTATTTATTCTTTGAATGTCTGCGTGCATTAATCATGAGATTATTATAATCCTGTAAATGTTATTACCAAAACATCAATAATAAAAAAAACTGAAGGGCATCTGTTGTTTCAAAGCTGTTTTACAGATGTTGATTGCTTAACATATAATATATTTAAGTGCTGACAGTAACATATCAGCATATATTGGTTTGTTTAAGATATATTATTTAATGTTTATGACATGCTTTCTTCTGTTTGGACTTGTTGTTGCTCTGGCTTGCTTTTGTCTTTTTTATCTGATGGGTTTTCCCCTATTGCGTCACATCTCTCATTGTCCCTGTCCTCTGCTTTTTACACTCTTTTTTTTCTTTGTACTCTACTTTATTTATGCTCTTATTTCTTTGTCTCTCGGCGTGTTTCTCTGTCCGCCATCAGGAAGCTGAAGT[T/A]GGAGAATGAGTTGACCGCTCAGCTGTGGCGTGTGCACTGGGAGGACATCCAGATGAGCAACACGGAGAAGGTCCTGCGCAGAGCCTGCAGCAAACTCACCATATCCCTGGTGAGGGCAAACATACTGTACACACACACACACAGACACACAGACACACACACACACACACACACACACACACACACACACACACAAACACACACACACACACACACACACACACACACACACACACACACACAGAGCATTGTAAATAAAAAGAAAAGAAAAAACAACACATTGAACTAACTTTTAAAAAAGTGATTTGTTACAGACAGTTTTTTATGTTATTGTTTTTCTTAAATAATTTTTTAACTTAATTTATTAAATATAATAATAAATACAGGAATAATATAATAATATAGTATATAATAAAGAATAATGTAACCTATTACACAAATACACTTCATTAAAAATGTACACATAGAAATCACCTAAGTAGGTTAACTTTGTTTACATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39249
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041298 Essential Splice Site 542 1067 9 21
ENSDART00000136244 Essential Splice Site 147 672 5 17
Genomic Location (Zv9):
Chromosome 19 (position 27067713)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 26997825
GRCz11 19 26582048
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTTCAAATGAGTCAGCAAACTAATGTCCTGTTAAAATCTTTTGCACACA[G/T]AGAGGCTCTAACTATGGGTCACTGCTCACTATGGATGGAAACTTCCAGAT
Long Flanking Sequence:
ACTTTAGACAAAAAATGGCTGCAATTATAAATTACCCCTTAAATTTTTGTTTTGACTTAGTTGGTATATTAATATATATCGATTTTTTTATATTAATGAAAATATTTATCCTGCCCAGTGAAACAATACATAGACCCAATAGTAAAATATTGTTTTTATAGACTATGATTAATTAATAAATTACGTTGGTTTGACTCATAATTAAATCCAGGTTTGTACTAAACTAAATAAATACATCTAATTGAATAAAACATGTAAATAATCCAAAACCATTATTTTTCACTTAGTCCAAATAATGTACCTTGAATGAAAGACACAGTAGTTACACCTTTTTGTCAATGAGGAATCAATGCAATGAGCTGATACAATATTTTTTTTATCATCTCGATTTATGTTTTTTTTATAATTGTTGGTAGCTAAAATCAAAATTTTGAATATTTGCTCAGCCCTAGTTCAAATGAGTCAGCAAACTAATGTCCTGTTAAAATCTTTTGCACACA[G/T]AGAGGCTCTAACTATGGGTCACTGCTCACTATGGATGGAAACTTCCAGATCTACGCTAAGACTGGCTACTACAAGGTATTTTAGGTTTGGCATTGAGTAGACATATGGAAAAAATGTAATAATTCAATACATCATGCTATTGAATATGCACAATCTGGGCCATATTAAGAACACAATTTATTTTATTTTTATTTTATCGCCTCACAAAAGTATATATTTTTGCTTTTATTATTGTTGTTGTTGTTGTTGTTATTGTCATTAATTTTATTATTATGAATTTACTAACTAATATTGTCTAATTTTCCACCATTTGATTTATACGTGATTATTATATATTATTTTTCTATTTCAAATACAAAATTAATTAAAAAAATAACATGAAAATTTAAACAGGTTGCTAAAATCAGCACAAAAAAAAACATTTGCAATACTTTCTAAAAATGTGCTTTTATAATGAATATTTTTAAATAGGGTTTTACCTTTAAAAAAGTTTCTGTAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10670
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041298 Nonsense 767 1067 15 21
ENSDART00000136244 Nonsense 372 672 11 17
Genomic Location (Zv9):
Chromosome 19 (position 27100211)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27030323
GRCz11 19 26614546
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACTWGGTTCTGTGTTTTAGAGATCATCGARCGTGTGGTGGAGGGCCGCTG[G/A]CCRTACCTGCGTCCCCTACTGTGTCCTCAGAGTCACAGTGAGGAGATGGG
Long Flanking Sequence:
GCCTCTGTCACTGACTGCTGTTTATCTGACATACCGCATGAGAAGCAGACATGCATGTGGAAATGGTAGGCGGGGTGAACCAGCTCATTTGCATTTAAAGACACAGGCTAAAAAAACAGCTTCATTTTGCTCTGAGACCAAAATAGGCACAATCTAATGTGAATTTTGAGCTGAAATTTTACAGACACATTCTGGAGACACTGAAGTCGTATCTTTACGTCTTGTAAAACGTTTTTTTTTTTTTTAAGTTTCCTGCTTGCTTCTCTCCATGATTTGCAAATTTTACCATATTGTTTTCAGTGTATATTTTCACTGCTAAAAACACAAGAACTGTTACAAATATAGACACAGTTCTTTAGAAAAGAATGAGAAAGAAAAGTCTTTTTAGGCCACAAAAATCGATAAAAATATCCCGTGAAATCCTGGAGGGACTGTTTGTTACATGTTTTGACTAGGTTCTGTGTTTTAGAGATCATCGAACGTGTGGTGGAGGGCCGCTG[G/A]CCATACCTGCGTCCCCTACTGTGTCCTCAGAGTCACAGTGAGGAGATGGGACAGTTGATGCTGCGCTGCTGGTCAGAGGACGTCAACGAGAGGCCAGACTTCAGCCAGATTAAAGTACTGCTCCGCAAGAACAACTGGTACATGACACACACACACATTCAAGTGATCATCATTTCACACACAGGAATTTAATTGACTTAACAAATTATATGAACGTCAACATTTTTGGTTGAATTTAAAGGTTCATTTGTAGATCATGTAAAATGCTAGTTTACCTCAGACTTGCAAAGATACTTGGCACTATTTAGCTGTGTAAGTTATACAGTTTTAAAAATGCTCTTATAAAATGTCATTTATTGATATAAAAATAAAATAATACAATACAAATAATAAATAATAGTTTACTTTAATATAATAATAGTTTTGTATAATAACTTTTAATTATGTAGAAAAAAAAATTATTTATTTAATTAATTGATTATTTTATTATATTTTTTGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44916
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041298 Essential Splice Site 862 1067 16 21
ENSDART00000136244 Essential Splice Site 467 672 12 17
Genomic Location (Zv9):
Chromosome 19 (position 27100972)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27031084
GRCz11 19 26615307
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGAGGAGAAACGAAAAGCTGAAGCTCTGCTCTATCAGATTCTCCCACAG[T/C]GAGTCCCACACACATCATGCATGAATGTCCTTTGGGATAATTTATGTGTG
Long Flanking Sequence:
AAAATGCTAGTTTACCTCAGACTTGCAAAGATACTTGGCACTATTTAGCTGTGTAAGTTATACAGTTTTAAAAATGCTCTTATAAAATGTCATTTATTGATATAAAAATAAAATAATACAATACAAATAATAAATAATAGTTTACTTTAATATAATAATAGTTTTGTATAATAACTTTTAATTATGTAGAAAAAAAAATTATTTATTTAATTAATTGATTATTTTATTATATTTTTTGGGGTGGAGACATATGCTGACCTGCTTATGGAAACCTGCATGCTCAGCCCTCTCACATGTCAGACACAGATTCACACTTCATTTCCCTGCCTCTCCTTCTATGTTTTGCCCTCAGTGGATACGGCTCTAATATTCTGGATAACCTCCTGTCCCGTATGGAGCAATATGCCAATAACCTGGAGGAGCTGGTGGAGGAGAGGACACAGGCGTACCATGAGGAGAAACGAAAAGCTGAAGCTCTGCTCTATCAGATTCTCCCACAG[T/C]GAGTCCCACACACATCATGCATGAATGTCCTTTGGGATAATTTATGTGTGCGCGCGTGCATACTGTCTCTCTGTCTAAAGTATGCAAATTTACAAACCACTTTTATTTTTAAAACCATTTATTTATGCATGTGTTTCTTGTTTTCTATTTGTTTGTTTGTGTTTAAATATTTCAATAAGTGTTATTTCAAAAATTGTTCATAAGCATAGCATATGGACAAAGTATTCGTAACGTCACCCATTGGTTTCTAAAGTGCAAATAAAGCTACAAGTGGGCGTGGCCAACCGTTTCCTTTTTTATTTGCATATCATTGTGCCAAACGAGGGTTACCATCAAAGGGTAAAGAAGCACGGAGAAACGCTATTTGGGAGAAACGCTTAATACTTCATTACCTGCGACTCGTTTGTGTTTTGACCACATGTGCTTGGTTGTGCACTATATCAACAAAGTGTTTAGTCTTTTAAAAGCACAGTTGTAACACATTGAGCCACTAAACATTG
Associated Phenotype:
Not determined