ZMP

si:dkey-79p17.3

Ensembl ID:

ENSDARG00000092404

ZFIN ID:

ZDB-GENE-081105-132

Description:

Novel protein similar to vertebrate lactase (LCT) [Source:UniProtKB/TrEMBL;Acc:B0UYB9]

Human Orthologue:

LCT

Human Description:

lactase [Source:HGNC Symbol;Acc:6530]

Mouse Orthologue:

Lct

Mouse Description:

lactase Gene [Source:MGI Symbol;Acc:MGI:104576]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa38764	Nonsense	Mutation detected in F1 DNA	Not yet available
sa27482	Nonsense	Mutation detected in F1 DNA	Not yet available
sa38763	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa38764

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000145110	Nonsense	298	1592	2	12
ENSDART00000145931	Nonsense	604	1898	7	17

Genomic Location (Zv9):

Chromosome 9 (position 47594313)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	46593116
GRCz11	9	46393595

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AACTTCATGCTGGGGTGGTTTGCTCATCCAATATTTGTAGATGGAGATTA[T/A]CCAGCGGTACTGAGGGAGCAAATTGAGAAAAAGAAAGAATTGTGTACCCA

Long Flanking Sequence:

GCCGAACGACCTGGCCATGAAAGTGCCTTCACTTTCATGGCCTTCACCTAGCAAAAGATGTACACACAACAGCGACTTTATGACACAACCATACCAGGGATCTGAGGGATTTAGTGAACACAAGATAGTGTGAACACAAACCAGCCGAGAGGGTGGCAAGAGGGAGCAATCAAACTTGGGTTTGGACCAGGCAATCGAACCAAGTGTGAAAGCACCCTTAGAAAGTCCCAAATATAGTATGATTTTAAAAAGTGTATACTGACAATTCTTTGCTTGTATTCACAGGTGACGCACAATATTCTGAAATCTCATGCTGAAGCCTGGCATATTTATAATGATAAATACAGGAAACTGTATGGTGGAAAAGTGGGCATTGCTCTGAACTCAGATTGGGCTGAGCCGAGGGATCCCTCAAGTGATCAGGATGTAGCAGCAGCTGAGCGTTATCTAAACTTCATGCTGGGGTGGTTTGCTCATCCAATATTTGTAGATGGAGATTA[T/A]CCAGCGGTACTGAGGGAGCAAATTGAGAAAAAGAAAGAATTGTGTACCCAAGACCTGGCAAGACTCCCTGTCTTCACCGAGGCTGAGAAACAAAGAATTCGAGGCACAGCTGATTTCTTCGGACTAAACCACCAAACATCCCGACTGATTAGTGAGAATTTGACTAGCTGTGATGCTGGGCCAGATAATGTTGGGGACTTCCAGGCTCATATTGACCCTACATGGCCCACTACAGCTTCTGACCAGATCCAGTCTGTTCCATGGGGGCTCCGGCGGTTATTGTATTACATCTTTTTAGAGTACACATCTATTACAAAGGTGCCCATCTATATCACAGGAAATGGAATGCCAACTGAGTATACTGGTGACGGGATCAATGACACTCTGCGTGTTGACTATCTCAAAGCTTACATTAATGAAGCAATGAAAGGTAAGAGTAAAAGGTCAAAAAAAGGGTCTTTTACTATTGCATTTTAACACTAAATGCTGCCATGAAAATA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa27482

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000145110	Nonsense	710	1592	3	12
ENSDART00000145931	Nonsense	1016	1898	8	17

Genomic Location (Zv9):

Chromosome 9 (position 47592942)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	46591745
GRCz11	9	46392224

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAATGGTTAGCATATTCAATGAATATTGTGACTTCTGCTATGCAACATTT[G/T]GAGATAGGGTGAAGTTTTGGATCACCTTTAATGAACCCCAGACGATTGCA

Long Flanking Sequence:

AGTTTTCACCTCAGACCAAATTTGAGAGGCAGCTTTATCACTATGGAACATTTTCAGAGGGATTTCAGTGGGGTGTCTCATCTTCAGCTTATCAAGTTGAAGGTGGCTGGAATGCAGATGGAAAAGGACCAAGTGTTTGGGATACTTTCACTCAGAAACCTGGTAATATCCCAAACAATGCCAATGGCGATGTTGCATGTGATAGCTACAATAAAGTAGATGAAGATCTACACATGTTGAGGGCCCTAAAAGTGAAGACTTACAGATTCTCATTGTCATGGTCTCGGATCTTTCCAAATGGCTATAAATCTTCTCTTAACCAGAAGGGGGTGGATTACTACAACAGGCTCATAGATGGTCTCATAGCAAATAATATCACACCCATGGTGACTCTCTACCATTGGGACCTGCCGCAGGCTTTACAGAATATCAATGGTTGGGACAACACTGAAATGGTTAGCATATTCAATGAATATTGTGACTTCTGCTATGCAACATTT[G/T]GAGATAGGGTGAAGTTTTGGATCACCTTTAATGAACCCCAGACGATTGCATGGTTGGGATATGGGCTGGGTCAGATTCCACCTAATGTGAAGCAACCAGGAGATGCTCCATACAGGGTTGCACACAACCTCCTGAAAGCTCATGCACAAGCTTATCACACATATGATGAGAAATACAGGGCATCTCAAGGAGGTCTGGTATCCATTAGTCTGAATGCTGAATGGGCAGAACCCCTGGATGTCAACATCCCTCGAGAGGTGGAGGCTGCTGATCGAGCTCTTCAATTTCAATTAGGCTGGTTTGCACATCCAATCTTCAAGAATGGTGACTACCCTGATGCCATGAAGTGGCAAGTTGGCAACAAGAGTGAACTGCAAGGCTTAAAAGAATCCCGGTTACCTTCTTTTACTAGCCAAGACAAAGCTTTTATCCAAGGAACAGCTGATGTATTCTGCATTAACACATACACTACGAAAGTCATGCGCCATGTGACCAGCAGA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38763

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000145110	Essential Splice Site	1361	1592	10	12
ENSDART00000145931	Essential Splice Site	1667	1898	15	17

Genomic Location (Zv9):

Chromosome 9 (position 47590427)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	46589230
GRCz11	9	46389709

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCATGTTTCTGAATTCAAGCATCAGGATTCAAAAAGTTGCCATTTATTCC[A/T]GGGGTGCTGGAGCTATTAGGGATCGTACATGGCTAGATTCTGGATCCATC

Long Flanking Sequence:

AAACAAGAAGACGTGGATGCTGCCAGACGTACGATTCAGGTACAGCTTTGTTGTACAGCGATATCTACATTAATTTCTACATGCCACTTCACTTTTTATCTCTTTTAAACAGTTTCAGCTTGGTTGGTTTGCTCATCCCGTGTTCAAAGGAGATTACAGTGATTTAATGAAGGATGTTATTCGAGAAAGAAGTTTGGCAGCTGGCCTACCTAAATCAAGGTAAATACAGACATTTTCTTGTGAGGAATTCACAACTTTGCATGCTTCTAAATGCCTTTACATTTGACAGGCTTCCAGAATTTACCCCTGAAGAAGTAGCAAGAATTAAGGGTACTCATGATTATTTTGGATTCAACCACTACACCTCTGTTTTAGCCTTTAACGTGGACTACGGTGATCAACAGCACATTGAAGCAGACAGGTAACCCTTTAGTTTGAGATGTTTTAGGTCCATGTTTCTGAATTCAAGCATCAGGATTCAAAAAGTTGCCATTTATTCC[A/T]GGGGTGCTGGAGCTATTAGGGATCGTACATGGCTAGATTCTGGATCCATCTGGTTGAAAGTAGCTCCTGTGGGATTCCGAAAGATTCTGAATTTCATTAAGGAGGAATATGGAAACCCTCCTCTTTACATTACAGAAAATGGAGTATCAGAACAAGGACCAGAGAATCTGAATGACGTCACCCGAATCTACTACTATGAAAACTATATCAATCAGGCCCTGAAAGGTAAAGATCTTTCCTCTTAAAGATGTCAAAAGGAACATTATTAAATGATTGTTTGCTATAATAGTTTTGCATGTATTTTTTTGTTTAGCATTTTCAGTTATTTGGTGCTAATTGCAGTGTTATTCTTAGCATATATGCTAGATGGTGTGGACATCCGCGGCTACACTGCCTGGTCACTAATGGACAATATGGAATGGGCAGCGGGTTATACTGAAAGATTTGGTCTTTTCTATGTAAATCGGTCAGATCCCAATTTTCCACGTATTCCTAAGAAA

Associated Phenotype:

Not determined