ZMP
mylk3
Ensembl ID:
ZFIN ID:
Description:
myosin light chain kinase 3 [Source:RefSeq peptide;Acc:NP_001099057]
Human Orthologue:
MYLK3
Human Description:
myosin light chain kinase 3 [Source:HGNC Symbol;Acc:29826]
Mouse Orthologue:
Mylk3
Mouse Description:
myosin light chain kinase 3 Gene [Source:MGI Symbol;Acc:MGI:2443063]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45291 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa27022 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa18088 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa45291
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000109918 | Nonsense | 408 | 715 | 5 | 13 |
| ENSDART00000142981 | Nonsense | 408 | 690 | 5 | 12 |
Genomic Location (Zv9):
Chromosome 7 (position 44574563)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 41564863 |
| GRCz11 | 7 | 41844936 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGTGCCAAGCAGGTTCCCATTAACTCATATTATGCTGTCAACCCTGTC[G/T]AGGTTCTAGGCGGGTAAGTCCATGTGTTATAAGCAGTTAATTCACCAAAA
Long Flanking Sequence:
GATACTTCACCCAAAAACCTCCATTATGTGACCTTTTTCTCTCCCTTCTGATGTTTAAAACTATTTGTTTTTCTTTCTTCTGTTGAACACAGAAGAAGATATTTTGAAGAAAGCTGGAAACCTGTTAGCATTGATTTGCGTAATATTTGTATTCCCTACTATGGTGTCAATGATTTCATGATTTCTTCGAAATATATTCTTTGCTGTTTAAAAAATGTAACTCATAAAGGTTTAAAATCACACTAGGATGGTAAATGGTGAATTAATTTAAATTTCTGGGTGAACTATCCATTGTGCAAATTGGGTCCGAGATGTCAGTGTTAATAAATTCAGCTTGTCACCATGCTACATCTTATATTTGGTTGATAGGTCGGCAATTCTCTAAGCATATTGATTTTCGTTTTCTAGATGACAGCCCACCTCTGCCAGCCCCATTCGACCATCGCATTGTCAGTGCCAAGCAGGTTCCCATTAACTCATATTATGCTGTCAACCCTGTC[G/T]AGGTTCTAGGCGGGTAAGTCCATGTGTTATAAGCAGTTAATTCACCAAAAAAAAAATGAAAATTCTGTCATCATATACACAATTTCTTGCAGTCCACTGAAAAAAAGGCCATGGCATAAATGATTGCAGAAGGTTTTTCATATAATTGGTGAATCACTTTAAAGCCATTTAATGCCGCTGGCTTAATATAACCAACCAGTATGCAGTTGATGAATCTAAAGACTGGAGATACAATGACAGTTTAATATTACAGATTGTGTGTGTGTCCATACAAAAAAACATTGATATATAGATGTATCATCAATTTTATCAAGTTCCATAAAAGGGAAATAATAGCATGAATGCTTCATTTGTAAAAAATCATGTTATTTTTTTCAGATATCTGTTGTGTAAAGACTGTCAGTCAGTGCAACTGTTAGTTAAAATAAAATCTAAACAAGTGTCTTTCATATATATATATATATATATATATATATATATGGTTTATAAGCATCCCTAAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa27022
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000109918 | Nonsense | 489 | 715 | 8 | 13 |
| ENSDART00000142981 | Nonsense | 489 | 690 | 8 | 12 |
Genomic Location (Zv9):
Chromosome 7 (position 44564932)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 41555232 |
| GRCz11 | 7 | 41835305 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTGTCCATGGTTTGTTATTGCAGCGTGGAGGGCGGCGAATTGTTTGAA[C/T]GAATCATTGATGAGAGTTACCAGCTGACGGAGCTGGATGCCATCGTGTTT
Long Flanking Sequence:
AAGTGTGACTTATTGTTCTACATTAATTCTTCTGCCTGATTAGTGGCTGCTGATCGTATTCATTAGGCCTTATTTGCAAATCAAATTCTCTCTCCTGGACTGATCTTCACATTCTGTCGCAAGAACACTGCGCTCCCACACATGCCACTTTACACAGCCATGATGGTGCGTCATCTTCCTGCCTTGTCCACAGATTACATTCACATTTGTTTGATGGCTTTGAATTCGCAGACAAATGCATTTAATTGTATGAAGAAATCTTTGAGCAAATGTTATTATTTGTAATGCAAGACACAACCATAGATAACAATAGCTTCTCAAAAGAATAGGTTCTATTATGAGTCTTAAAATTCTGTTTTACTTAAGTTGGCATCCTCAAGTGAATACGTCAATACACATGTTCACAGTGAACTAATAGAGAGGAGATAACATGATGCTTCATTCCAAAATATCTGTCCATGGTTTGTTATTGCAGCGTGGAGGGCGGCGAATTGTTTGAA[C/T]GAATCATTGATGAGAGTTACCAGCTGACGGAGCTGGATGCCATCGTGTTTACCAGGCAGATTTGCGAAGGGGTTCAGTACCTTCACCAGCAGTACATTCTCCATTTAGATCTTAAGGTAAACCTCACAGAACGAACTGAATGCTTTAACGTGATACTGACGGGATTAGCAGTGCATAGTGTCAAGTAGCTCTATGGAAAAATCTACCAATGAATCAGCCATGTATGTCAACATCAGCCGTCTGAATGTCGTACATTTTAATTAGCATAGCACTAAAGGACTCGTGCCTTGTGTTGCTGTTAACATGTTATGCAGCAATCTGGAATGTTTACCATATGCAACAGCACCAATCCACATCAATTATGTATGTAAATGTAAATTGTGAGTTTGGTGGTTTTGTCTTTATAACATTGAATCCTGTATTTAGTTTGAAATACTAATGCTTTTACACATGGACCACAAAACCAGTCATGAGTGTCTTTTTTAATTCAGTATTTAAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa18088
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000109918 | Essential Splice Site | 594 | 715 | 11 | 13 |
| ENSDART00000142981 | Essential Splice Site | 594 | 690 | 11 | 12 |
Genomic Location (Zv9):
Chromosome 7 (position 44555400)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 41545700 |
| GRCz11 | 7 | 41825773 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
RAGGGTGAACAGATTTAAGTTATTTTYACYCTCTGTGATTTCATTTTTTC[A/T]GTTTGAGTGGCCTTTCTCCATTCMTGGGTGACAACGACGCAGAAACAATG
Long Flanking Sequence:
ATAAACATGGCACTTGTCAATTAATTCAGAGGGTGGGGAAAACCTACGTCACAATGCGGTGGGCCTCAAAAATCACGGGGATTTGGATCATTTTTAAACATCAGGCAATTGAAAGAAAAAAAAAAAAGAGAGACTTGTGTTTCTATCACTCCAATATGACAGTGGACACTATACCTACAGTCAGATTTGTCCAAACAGCTTCCAAAAGCTGATTTTTAATCACAGGTGCCCTTTAAGTGTAGATATTTATTAAGATAATGACCGTAAACTAAACATGCAAATGAAGAAAAAGAAAGTTTTTCTGACTAATTGATCAATTATATTCTAGCAACATTCACGGTGCTGTGAATTATGCACATTTCAGAAATAGACCAGAACAGCACAAAAGAAACGAGTGCACCTTTTGCCCATAATTGCTTCTTCACATCATACCTTGAAAAGCTTAAAACTAAGGGTGAACAGATTTAAGTTATTTTCACTCTCTGTGATTTCATTTTTTC[A/T]GTTTGAGTGGCCTTTCTCCATTCATGGGTGACAACGACGCAGAAACAATGAACAACATTCTGCACGCCAAGTGGGAATTTGACACGGAGGCATTCGAGAATGTGTCAGAGGAAGCCAAAGACTTCATATCCAGCCTTCTTGTGTCCGCCAAATGGTATTCATCCATCATTACTCCACTAATGAAAACCTCACAGTGCAGACTAACCCAGAAGTCACACATTCTATTTCACAAACTTCTATACGCCCTCTCGTATTTCTCCTCTCATCTGACCTCCTGCTCCTGGATAAGAGCCTCACTTTTCTCTTCCATCCCTCAATCATTGCCCCACTTTGACCTGCTCAGGTTCTTTTAATGCATCCTGACATCAAACCTGAAAAAAGGCACAAATAACATATAATTGGACAGAGACGCAACATGGCCTGGTGCATTTTAGAGCATTTGGAGCTCCCTCTCACAATGCGTTGTCTTAGCTAACCTCTCCCACACAGGGGCTGTACTG
Associated Phenotype:
Not determined