Busch Lab

ZMP

ppp2r5eb

Ensembl ID:
ENSDARG00000069118
ZFIN ID:
ZDB-GENE-030904-6
Description:
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform [Source:RefSeq pe
Human Orthologue:
PPP2R5E
Human Description:
protein phosphatase 2, regulatory subunit B', epsilon isoform [Source:HGNC Symbol;Acc:9313]
Mouse Orthologue:
Ppp2r5e
Mouse Description:
protein phosphatase 2, regulatory subunit B (B56), epsilon isoform Gene [Source:MGI Symbol;Acc:MGI:1

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa35564 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa2677 Essential Splice Site F2 line generated Not yet available
sa22360 Essential Splice Site Available for shipment Available now
sa13799 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa35564
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100324 Essential Splice Site None 467 None 15
ENSDART00000123376 None None 467 None 13
ENSDART00000147336 None None 134 1 4
Genomic Location (Zv9):
Chromosome 13 (position 37862712)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37339524
GRCz11 13 37465414
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATTTTTGGATACAAATAACCTGCAAACGCGGCGTGTGGATATAAAGAGG[T/C]ACCCGGGGATGTTCGTATTTCAGCTGGATCTATTTCTATCGTCGGAAAAT
Long Flanking Sequence:
TTGTTTATACTTTTTTCTTTTAATAAATTTGTACTTTGCACAAAACACATTCAAGCTTTTACAAAGGATCGTGCATTAATAAACTTTCGCATTCGAAACAGATGTGCATGAATTAGTTTTATTATTTTTGCAATAAAACACATGATATAATTAAAACACTAAGACAGAATAGTAAGGTGACTCTCTTTCCTGCTCGCACACACCTCAACCCAACTTCTCTATTCATCGTAAAGGGTAGCCTTGGAGTTATCCACCCTCCCTTGCTTGGTGATTGACAGTATTATCGCCCAATCACGTCTTCTGGATTCTTCAAACTGACCAATGGCGTGGCGCTGTAGGCCCGAACCCGGCCCAGCATGGTAGAACGCGTCCGTGTTATGTGTGCCATGGACTCAGCCCAGTAATATTGACAATAGGGCGAAAAAGGGACCGATATTCCCTAAGAAAACATATTTTTGGATACAAATAACCTGCAAACGCGGCGTGTGGATATAAAGAGG[T/C]ACCCGGGGATGTTCGTATTTCAGCTGGATCTATTTCTATCGTCGGAAAATTGAGTGTTTGATGGGATTATTGCTGTGGGTTTGGCAGTTTTTAAGGCCAAAAACGGATTTTGTGTCTTTATTTTTATTTTTCTGCTGCTTCAAGAGGCCTTGAAGGAGGAAAGACGGTTAAAAACACTCAAATCAGTTCCTCACATCGAAAACATCAAGGTAAATTCAATATTTGAAGGTTTTTATTTCGCCTATCATGCTCAAGTTGAGATCCGGTACGTTTTGATGTTTCACATCCCAAAGTAAATAAGTCAAAAATAAGTTAAAGCTTCAAAACATTTCCTGTACAGTTTCTAAAGAGTTGTATGTTGTATTAGTTAGCTAAAAGGAGCAATGAAACCCCCCCACTCAATATTTCCCACACATGTTGACTTGTAGGCAGCATATGAATGGGTGGATGAGTGAAAATCCGCAAAGAAAGCTCATTCTTCATCCGTTGTAGTTTGCAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2677
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100324 Essential Splice Site None 467 3 15
ENSDART00000123376 None None 467 None 13
ENSDART00000147336 Essential Splice Site None 134 2 4
Genomic Location (Zv9):
Chromosome 13 (position 37853765)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37330577
GRCz11 13 37456467
KASP Assay ID:
554-2498.1 (used for ordering genotyping assays)
KASP Sequence:
AGTTGCTGCTGYGTTTATGTTGTCTTACATGTCTTTTTCCCTATTTTTTT[A/T]GGGCTATGTCCTCCGCAGCCACCACTCCTCCATCAGTGGATAAAGTAGAC
Long Flanking Sequence:
TGTGAAAATTAGTATGACTGCCTTTATGCTTCTCCTGAACTTCTACCGAAAGTAAAATTGGCTGAATCGTAGAGATGCTGGATTGTATTTGTGTGGGGGTCGAATGGCGATTGCAATCTTTTTTTCGATTAATCATGCAGCCCTAGTCAGAGATTATGTACTGTCATCATGGCCAAATAAAATAAATCAGTTATTAAAAATCAGTTATTAAATCTATCATGTTTAGAAATGTGTTGAGAAAATATTTTTTTTGTTAAACAGTAATTGGGGAAAAATATACAGGGCGTCTAATAATTCACAGGGGTTAATAATTTCAACTTCAACTGTAATTTTTTTGTTTCAACATACTTTCTTTGAGAAAAAAAATGCAACGACACTTTTTTTTTTTTTTTTTTGGGTATGCAAAGAGCAAATTTGAGACCATATTGGCATAATACTTTCCACTGATGCAGTTGCTGCTGCGTTTATGTTGTCTTACATGTCTTTTTCCCTATTTTTTT[A/T]GGGCTATGTCCTCCGCAGCCACCACTCCTCCATCAGTGGATAAAGTAGACGGATTCTCCCGGAAGTCTGTCCGGAAGGCCAAGCAGAAACGTTCTCAGAGTTCCTCACAGTTCCGCTCTCAGGGCAAACCAATCGAGCTCACACCTCTTCCCCTGCTCAAAGGTGAAGCACTTACGATTATTAAATACTCGCATAACAGCTAATAACTTTCCTCTAAAGTCATTTGGCTTCGGGAATTGATATGAAGCAGTGTGACATTCTTGGTTCAGTGGTATAAAGCGAATAAGCATTAAACCTGTGCTGTAAATTTAAAGCTGATGTTTCAAAAGATCTTGTTTTCAAAATGCTAACGTAATTAGCTTATTTAAATAAGGACTTGATATAGTTACTTTCTTTTTGTATTAGTGTTGTCACGGTACTGTAATTTCAGTACCAACAGGTACTGGAATTTTAAAAAGTCCATTACTCGCTAACATTTAACCGCTGTTGAGATCAAAAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22360
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100324 Essential Splice Site 184 467 7 15
ENSDART00000123376 Essential Splice Site 184 467 5 13
ENSDART00000147336 None None 134 None 4
Genomic Location (Zv9):
Chromosome 13 (position 37826788)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37303600
GRCz11 13 37429490
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTTAAGTAGTGTTTGTTGTTTATCTTTTTGTTCATCTGTCTTTCTCTCA[G/A]CTGCTGGAGTTGTTCGACAGCGAGGACCCACGAGAAAGAGATTACCTGAA
Long Flanking Sequence:
CCTTTAGAAATGAGATGCATATCTCAAGGAGAATCTTCCTGGTAAAACTTTTCTCTTTTGTTTCATCATTAATCCCTGCTTTTGTCTTTTTTTCATCTGGAAAACAATTTTAAAAGTTCAGTTTTGAAAAGCCACATTCCCAGATATGTGTTCCTCGTCCTGTGTTATCATGGGAACAACTAACGGCGGCAGTAGCAGTGTCCTGTGACCTCAGTCGAACCATGACCTTTTTCCCCCACTTTGCATTTCTTCGTGCATGCCAAGTTTGAAGAGCTCCACCAAGTAACACACACCTCTCGTCTCTGTTCTCAGCTGGTGTATGAGTTCTTCATTCGGTTTTTGGAGAGTCAGGAGTTTCAGCCCAGCATTGCCAAAAAATACATAGACCAGAAATTTGTCTTACAGGTGAGAATGTTCATTTTTAAAAAGATTCTCCTTCATTTCTGCTTTATTTAAGTAGTGTTTGTTGTTTATCTTTTTGTTCATCTGTCTTTCTCTCA[G/A]CTGCTGGAGTTGTTCGACAGCGAGGACCCACGAGAAAGAGATTACCTGAAGACAGTCTTACACAGAATCTATGGAAAATTCCTGGGACTGAGAGCTTTTATACGAAAACAGATAAATAATATTTTTCTACGGTGAGGGATTTAACGTCAGCATTTGTATAGTATTAGGCCTAATGCGGAATGAAAAGCAAGCACTGATGTGTCTCTCTCCCATTCCTAGTTTTGTTTATGAAACTGAGCACTTCAATGGAGTCGCAGAATTGTTGGAGATTTTGGGCAGGTGAGGAGTATTTGCTTGTAATAGAAGTAGTGACTGATAGTTAATTTTTGGTATTGTGATGTACAGTTTAAACCAGAAGTTTACATACACTGTATAAAAAAGGCACATAACCATTTATAAAAAAAAGTCAGATGTTAATGTGACTAAACTTTTTCTCTTTTAGGTAAGTTAGGATTATCAAATTTGTTTATGTTATGCTTAATAGCAGAATAATGAGAGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13799
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100324 Nonsense 399 467 13 15
ENSDART00000123376 Nonsense 399 467 11 13
ENSDART00000147336 None None 134 None 4
Genomic Location (Zv9):
Chromosome 13 (position 37821102)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37297914
GRCz11 13 37423804
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATTCTTCCAATAATGTTCGCCAGTCTTTACCGGATCTCCAAAGAACACTG[G/A]AACCCGTGAGTCAAACCTACACCACCAACACAATCTCTCAGCCTATAAAT
Long Flanking Sequence:
ATCAGCCTTAACTTAAGTATAGAATGTACAGTAGATTGCAATATAAAAAGCTCAAGAAACACGACATGCTCATTTCAAAGCACTCCATAATTGCTTATGCACTGTCCATTATTCTATGTGCAATGAACATTTTGACTAATTCTTGTAAGTTTTATTCATATTTTGTCTATGTGCAAAGGTCATTTTCTCCATATCAAATATATTTTTTACAATCATTTTCCAATTTTCTTCAAAGTCTGTTCTTACAAAAACTAGAAGGTTTATTTTCATTTTTTTAATGCATTAATGCTGCTTCTATGAATGCATGAAGCAGCTAAGAATACAATGCATCCAAATCCTAGATGAATCGTGTAAGTTTGTAAATGAATGTGTGTCCAGGTGGCTGAGAGAGCTCTGTACTACTGGAATAATGAGTACATCATGAGTCTGATTGAGGAGAACTCCAACGTGATTCTTCCAATAATGTTCGCCAGTCTTTACCGGATCTCCAAAGAACACTG[G/A]AACCCGTGAGTCAAACCTACACCACCAACACAATCTCTCAGCCTATAAATAATCTAGGCTCTTTTGTTCCAATCACATTTAATGTTTTCATATGTTATCCTTCCATAATTATGGTTTGTAAGATAAAGTTGTTTTGGGGCAATAAATGATTTTTTTTTTTTTAACTAAATATCAAGTAGTCGATTACAATCTTAATTGAATATAAATATTTGTTTGCCTTCTTTGAACTTTCTATTTATTAAGTGATAGAATTTGGTCTTTTTTTAACATCATTTATAATAAAAAATATTTATTGAGCAGCAAATCACCATAATTTCAAGAGGATGTGACCTCAAAGTTAGTATTAGGATTTTATCAGTTTTGTACAGAGGTGAACACTCAGCCTTTAAATGTTCAGTATATTTGTATGTTAATGCTTCACAATATTCTCATTACTGTTCAGCATTAATTAAATATTGCCATCTACTGGATTAAACATGCCCTGTTCTTCCAGTCCCAGT
Associated Phenotype:
Not determined