ZMP
zgc:158824
Ensembl ID:
Description:
pre-B-cell leukemia homeobox 1 [Source:RefSeq peptide;Acc:NP_001077322]
Human Orthologue:
PBX1
Human Description:
pre-B-cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:8632]
Mouse Orthologue:
Pbx1
Mouse Description:
pre B-cell leukemia transcription factor 1 Gene [Source:MGI Symbol;Acc:MGI:97495]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa15193 | Essential Splice Site | Available for shipment | Available now |
| sa26652 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa15193
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000122028 | Essential Splice Site | 17 | 275 | 3 | 9 |
| ENSDART00000125538 | Essential Splice Site | 88 | 429 | 3 | 10 |
| ENSDART00000129503 | Essential Splice Site | 88 | 429 | 3 | 9 |
Genomic Location (Zv9):
Chromosome 6 (position 2168031)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 2193527 |
| GRCz11 | 6 | 2371896 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGGATRTTGGAGCWGTGTCAGTAATCTTYCTCTGTTTGCTTTGTGTTTT[A/C]GTGTTGAGTATCCGTGGAGCTCAGGAGGAGGAGCCTCCCGACGCTCAGCT
Long Flanking Sequence:
TGTGCTTTTTTTAAAAAAAAGAAAAAGTATATAGTGGGTGTGTGTGTACTTGTTTTTATACACCAGTGGGGACTTAAACATGAATACACACAAACTCATGGGGACGTGTGTCAACTTTGGGTGTGTATGTGTGCATGTGTGTGTAGTGTAAGTGTAGGTGTTTGTATGCAAGTGTGTTTTACCACTACAGATCTGGTGTAAACTCAGTCACTGAGTCCCTCTAGTGTGGGATCTTCAGAGCGCAGGGATCACTGTGAGATTTACAGCCACACGGCAGCTCTGCTCAGTGGGAAGATCATATGAATTAGATGAAGTTGTATTATATATCATCATAAAACCTGGCAATGTCAACTGCAGCCATGGCCGGGAACGAGTTTTTTTGGAGGGTTTCTGCTAAAAGTCTATTCATCAGAGCAGATTGTGTGTGGATGGATGAAGCCATGTGTATTCTGGGATGTTGGAGCTGTGTCAGTAATCTTCCTCTGTTTGCTTTGTGTTTT[A/C]GTGTTGAGTATCCGTGGAGCTCAGGAGGAGGAGCCTCCCGACGCTCAGCTGATGCGATTGGACAACATGCTGCTGGCGGAGGGCGTGTCCGGGCCGGAGAAAGGGGGCGGGTCTGCGGCGGCAGCGGCTGCAGCTGCGGCTTCAGGAGGAGTCGGAGCCGATAACTCCGCCGAACACTCTGACTACAGAGCCAAACTCTCACAGATCCGCCAGATCTACCACACTGAGCTGGAGAAATACGAGCAGGTCAGCAAACATGTAATAATGATAATATATTTCTTTATTTATTTTATTTATTATTGATTTGAAATAATGGGACTAAGCCGAAAAGAAAATGGATGAATTGATTTGAAATATGCTTGTGGTGGGAGACAAACAAACTGGCGCAGTAGGTAGTGCGGTCGCCTCACAGCAAGAAGGTTACTGGTTTGAGCCTCGGCTCAGTTGGTGTTTCTGTGTGGAGTTTGCATGTTCTCCCTGCGTTCGCATGGGTTTCCTCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa26652
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000122028 | Nonsense | 166 | 275 | 5 | 9 |
| ENSDART00000125538 | Nonsense | 237 | 429 | 5 | 10 |
| ENSDART00000129503 | Nonsense | 237 | 429 | 5 | 9 |
Genomic Location (Zv9):
Chromosome 6 (position 2177908)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 2183735 |
| GRCz11 | 6 | 2381688 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCTGATTTCTCTCTCTCTCTCTCTCGCTCTCTTCACAGGAGGAAAAGA[C/T]GAAACTTCAACAAACAGGCCACAGAGATCCTGAATGAGTATTTTTACTCT
Long Flanking Sequence:
GCGGAATGGACCACCAACTTTTTCCAGCATATGTTTTACACAGCGGTTGCCCTTCCAGCTGCAACCCAGTACTGGGAAACATCCATACACACTCATTCACACACACACACACACATACACACTACGGCCAATTAAGTTACTTCAGTTCCCCCATAGCGCATGTGTTTGGACTGTGGGGGAAACCGGAGTACCCGGAGGACTTGAACCAGCCAGCCAGGGCTTGAACTAGCGACCTTCTTGCTGTGAGGTTACAGTGCTAACCACTGAGCCACAGTGCCGCTCTTCATTCCATTTTTGAAATTTTAGCTTACTAGTTTATAAAACCTGGAGTGATTCTTAACCAAATGATTTGTCTCTAAAATTTCTCCAAAGTAATGGTTCATTATTGTGGCCTTTTCTATATTTGCCAATATGAAGCATTAATTATATGCAAAGAAAAAAGTATGTTCACATCTGATTTCTCTCTCTCTCTCTCTCGCTCTCTTCACAGGAGGAAAAGA[C/T]GAAACTTCAACAAACAGGCCACAGAGATCCTGAATGAGTATTTTTACTCTCACCTCAGTAACCCGTATCCCAGTGAGGAGGCCAAAGAGGAGCTGGCCAAGAAATGCTCCATCACCGTCTCACAGGTGCTGAAATACACATCGCTGACAATCCTCTCTGACATTACGCCCTGAAAACATAGATATAGATCCTACTTTAGTCAAAATACAGACCCCACTATATTGCAATTGCTTGTAATATGATGATTCCAAAATTAAAGATGTGGCTTGCAATTTCCAGCATACTTTTCATGTACTGTACTACTCATAGGCTGTGTCTGAAATCGCCTCCTACTCAGTTGGTACTGCATTTGAATTTACACGTACTACTCAACCATTAGAAAAGGATGTTCTATATACAGTGGGAATGTGAGTAGTATGAATGGAACTCGGACGTAGTACATCTGTCAATTTGGTCACGTGATCTACCCACATCAGTTGCCATTCTTGAATTGTGTCGCA
Associated Phenotype:
Not determined