Busch Lab

ZMP

NP_001138254.1

Ensembl ID:
ENSDARG00000004796
Description:
probable E3 ubiquitin-protein ligase MGRN1 [Source:RefSeq peptide;Acc:NP_001138254]
Human Orthologue:
MGRN1
Human Description:
mahogunin, ring finger 1 [Source:HGNC Symbol;Acc:20254]
Mouse Orthologue:
Mgrn1
Mouse Description:
mahogunin, ring finger 1 Gene [Source:MGI Symbol;Acc:MGI:2447670]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa20151 Nonsense Available for shipment Available now
sa26156 Essential Splice Site Available for shipment Available now
sa31361 Essential Splice Site Available for shipment Available now
sa25264 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa20151
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008988 None None 441 None 15
ENSDART00000078221 Nonsense 72 549 3 16
Genomic Location (Zv9):
Chromosome 3 (position 55704143)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54597869
GRCz11 3 54852471
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATATTAAAATGTGAGTAATATATATTTTTTTATTTCTGGCAGTTTCCCTA[T/A]GTTACTCCAGCTCCGCATGAACCAGTCAAGACATTGAGAAGTCTTGTCAA
Long Flanking Sequence:
TTGTTTTAGCTCTTTTGGTCTGATTAGAAACTTGCAGTGTGAAAGCGAACTGCTCCAAGATCAAAGAGCAACAATGTAACAATTGTAATCTCTGTTTCGGAACAACTGAATCGATTCATAGGTGTGAAAGCACCCTAAATGTTTGCACCTTGATACCTTGTTTATTTTTTAGCCTGAATTTAATTTGATTAGAAAACTATTTCCTGTTTATTTTAGTATAATCATTAAATAAATTAATGATAATGAATGAAATGGTGAATAAAAGTGTCATTTATTTAGCGGGGAATGTTAAATTGCACTAGATATCAAGATTGCTCTCATTATAATCTTATATATTCTCATTATAACAGAGCCCTTTGTAATATCTTATTATAAATGTTTTATATATTATGAATGAGACTTTTGATACATTTGTTTTGTTGTAAATGGTTTTAGTAAACGCATACTGATATATTAAAATGTGAGTAATATATATTTTTTTATTTCTGGCAGTTTCCCTA[T/A]GTTACTCCAGCTCCGCATGAACCAGTCAAGACATTGAGAAGTCTTGTCAACATTAGAAAGGACTCATTACGATTGGTCAGGTACTGTATGAACATCATATCGCTGGTAGTCTGAGTGAAAATAATCTCAGTGCTGAGTATAGTTGCATTTCTCTTGATCATTTGTGTATTTGTTTTAAATTTGTGTGATTGTAGGTATAAAGATGATGCTGATACTCCTACTGATGAAGGAGTAAAGCCAAGGGCCATGTATGGAGTGGAGTTCACCTTTGACTCTGATGCACGGGTGGCCATCACTCTCTACTGTCAGGCCTTTGAGGAGTTCTCCAATGGGATGGCGATGTAAGATCTTTAGTTGTAGTTGCAAATTTTTAAAGCTACAATGAAGCAGATATGGTGATTTATATTTTTCCTTTTTGCATTTTGACATGCATTTCAGTTTGTAAACTGTTAATGACAAAATAATGTAATGCAAGGTCTTAGTTTTGTTAGAATATTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa26156
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008988 Essential Splice Site 15 441 None 15
ENSDART00000078221 Essential Splice Site 99 549 None 16
Genomic Location (Zv9):
Chromosome 3 (position 55704225)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54597951
GRCz11 3 54852553
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTGAGAAGTCTTGTCAACATTAGAAAGGACTCATTACGATTGGTCAGG[T/G]ACTGTATGAACATCATATCGCTGGTAGTCTGAGTGAAAATAATCTCAGTG
Long Flanking Sequence:
TTGTAATCTCTGTTTCGGAACAACTGAATCGATTCATAGGTGTGAAAGCACCCTAAATGTTTGCACCTTGATACCTTGTTTATTTTTTAGCCTGAATTTAATTTGATTAGAAAACTATTTCCTGTTTATTTTAGTATAATCATTAAATAAATTAATGATAATGAATGAAATGGTGAATAAAAGTGTCATTTATTTAGCGGGGAATGTTAAATTGCACTAGATATCAAGATTGCTCTCATTATAATCTTATATATTCTCATTATAACAGAGCCCTTTGTAATATCTTATTATAAATGTTTTATATATTATGAATGAGACTTTTGATACATTTGTTTTGTTGTAAATGGTTTTAGTAAACGCATACTGATATATTAAAATGTGAGTAATATATATTTTTTTATTTCTGGCAGTTTCCCTATGTTACTCCAGCTCCGCATGAACCAGTCAAGACATTGAGAAGTCTTGTCAACATTAGAAAGGACTCATTACGATTGGTCAGG[T/G]ACTGTATGAACATCATATCGCTGGTAGTCTGAGTGAAAATAATCTCAGTGCTGAGTATAGTTGCATTTCTCTTGATCATTTGTGTATTTGTTTTAAATTTGTGTGATTGTAGGTATAAAGATGATGCTGATACTCCTACTGATGAAGGAGTAAAGCCAAGGGCCATGTATGGAGTGGAGTTCACCTTTGACTCTGATGCACGGGTGGCCATCACTCTCTACTGTCAGGCCTTTGAGGAGTTCTCCAATGGGATGGCGATGTAAGATCTTTAGTTGTAGTTGCAAATTTTTAAAGCTACAATGAAGCAGATATGGTGATTTATATTTTTCCTTTTTGCATTTTGACATGCATTTCAGTTTGTAAACTGTTAATGACAAAATAATGTAATGCAAGGTCTTAGTTTTGTTAGAATATTAATTCATTTATTTATTTTTTTTGTTATCACTTCCATATATTTATAAATAAATAAATAACCATAGTAAAAATAAATAGAACCAACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31361
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008988 Essential Splice Site 179 441 7 15
ENSDART00000078221 Essential Splice Site 263 549 9 16
ENSDART00000008988 Essential Splice Site 179 441 7 15
ENSDART00000078221 Essential Splice Site 263 549 9 16
Genomic Location (Zv9):
Chromosome 3 (position 55707018)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54600744
GRCz11 3 54855346
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTACAGGAGATTTATGGAATTGAGAACAAAAATAATCAGGAAACAAAGG[T/C]GAAAAGAGGATTGTTGTTCATTTTCATTATGTTATTCATCAATTAGCCAA
Long Flanking Sequence:
AGTCCAACTTGACACTGCACACTGATCATATTTGTGGTTATTTGTGCAAAAAAAGACACAAGAAAGAGATTTATAGACTTGGTGTTGCCCAAATAATCCAAGAAAAGAAACAGCAGTGTTTGCTTACGGCTGTCATTTCTTGTATTTATTTTTGTTTCAGATTGTTTTGGACATGCTCATGTACTGCTTGCAGCATTTGAAAGAGTGAGTTTTATATTATTTCGTGCATTTGATTTCTAAATCTTTGCTGTTCTTTTTTTTTGTGAATTTCTGATGATAATTTTGTTTAATACAGCATGTCGATGGCAGTTTCTCAGTGAAACCTTTGAAGCAGAAACAAATAGTGAGTCTGTTTTTATTTTAAATGAAGTATAAAATAGAGCAATAGATGTTTTCATAATGGCCATTTTTTTTTGTTTTTTTGCTACAGGTGGATCGTGTTAGTTATTTGTTACAGGAGATTTATGGAATTGAGAACAAAAATAATCAGGAAACAAAGG[T/C]GAAAAGAGGATTGTTGTTCATTTTCATTATGTTATTCATCAATTAGCCAATGGTTTGGTATAATTCAGATTTTTAATGTTTAGAAATGTTGGATTTTTTTGATTTTTAAAAAGAAAGTAAATATTGAGGGTGACGTAGTGGCGCAGTAGGTAGTGCTGTCGCCTCACAGCAAGAAGGTCGCTGGGTCGCTGTTTCGAACCTCGGCTCAGATTCTGTGTGGAGTTTGCATGTCCTCCCTTCGTTTGCGTGGGTTTCCTCCAGGTGCTCTGGTTTCCCCCACAGTCTAAAGACATGCGGTACAGGTGAATTGGGTAGGCTAAATTGTCCATGGTGTGTGTGTGTGGATGTTTCCCATTGATGGGTTGCGGCTGGAAGGGTATCCGCTGCGTAAAAACCTGCTGGATAAGTTGGCGGTTCATTCCGCTGTGGCGACCCCAGATTAATAAAGGGACTAAGCTGACAAGAAAATGAATGAATGAATGAATGAATAAAGTAAATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25264
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008988 Essential Splice Site 179 441 7 15
ENSDART00000078221 Essential Splice Site 263 549 9 16
ENSDART00000008988 Essential Splice Site 179 441 7 15
ENSDART00000078221 Essential Splice Site 263 549 9 16
Genomic Location (Zv9):
Chromosome 3 (position 55707018)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54600744
GRCz11 3 54855346
KASP Assay ID:
554-7838.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTACAGGAGATTTATGGAATTGAGAACAAAAATAATCAGGAAACAAAGG[T/C]GAAAAGAGGATTGTTGTTCATTTTCATTATGTTATTCATCAATTAGCCAA
Long Flanking Sequence:
AGTCCAACTTGACACTGCACACTGATCATATTTGTGGTTATTTGTGCAAAAAAAGACACAAGAAAGAGATTTATAGACTTGGTGTTGCCCAAATAATCCAAGAAAAGAAACAGCAGTGTTTGCTTACGGCTGTCATTTCTTGTATTTATTTTTGTTTCAGATTGTTTTGGACATGCTCATGTACTGCTTGCAGCATTTGAAAGAGTGAGTTTTATATTATTTCGTGCATTTGATTTCTAAATCTTTGCTGTTCTTTTTTTTTGTGAATTTCTGATGATAATTTTGTTTAATACAGCATGTCGATGGCAGTTTCTCAGTGAAACCTTTGAAGCAGAAACAAATAGTGAGTCTGTTTTTATTTTAAATGAAGTATAAAATAGAGCAATAGATGTTTTCATAATGGCCATTTTTTTTTGTTTTTTTGCTACAGGTGGATCGTGTTAGTTATTTGTTACAGGAGATTTATGGAATTGAGAACAAAAATAATCAGGAAACAAAGG[T/C]GAAAAGAGGATTGTTGTTCATTTTCATTATGTTATTCATCAATTAGCCAATGGTTTGGTATAATTCAGATTTTTAATGTTTAGAAATGTTGGATTTTTTTGATTTTTAAAAAGAAAGTAAATATTGAGGGTGACGTAGTGGCGCAGTAGGTAGTGCTGTCGCCTCACAGCAAGAAGGTCGCTGGGTCGCTGTTTCGAACCTCGGCTCAGATTCTGTGTGGAGTTTGCATGTCCTCCCTTCGTTTGCGTGGGTTTCCTCCAGGTGCTCTGGTTTCCCCCACAGTCTAAAGACATGCGGTACAGGTGAATTGGGTAGGCTAAATTGTCCATGGTGTGTGTGTGTGGATGTTTCCCATTGATGGGTTGCGGCTGGAAGGGTATCCGCTGCGTAAAAACCTGCTGGATAAGTTGGCGGTTCATTCCGCTGTGGCGACCCCAGATTAATAAAGGGACTAAGCTGACAAGAAAATGAATGAATGAATGAATGAATAAAGTAAATAT
Associated Phenotype:
Not determined