Busch Lab

ZMP

LOC100330155

Ensembl ID:
ENSDARG00000018619
Human Orthologue:
LASS4
Human Description:
LAG1 homolog, ceramide synthase 4 [Source:HGNC Symbol;Acc:23747]
Mouse Orthologue:
Lass4
Mouse Description:
LAG1 homolog, ceramide synthase 4 Gene [Source:MGI Symbol;Acc:MGI:1914510]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa39954 Nonsense Mutation detected in F1 DNA Not yet available
sa1656 Essential Splice Site Available for shipment Available now
sa9557 Nonsense Available for shipment Available now
sa25943 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa39954
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036240 Nonsense 18 402 1 10
Genomic Location (Zv9):
Chromosome 2 (position 56598408)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 56261476
GRCz11 2 56385321
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGATGCGCTCAGCCGGTGGTTCTGGAAGCAGGAGATCTGGCTTCCCCCA[G/T]GAATCGTCTGGGAGGATCTGGAGGAGATGCAGGGCTCTCGGCGTCCAATG
Long Flanking Sequence:
AATTTTATTTTCAGGTATTTCCCATATGGTGTTTAGCAGATTCAGGAATTTTTCACAGTATTTCCTATAATATTTTTTCTTCTAGAGAAAGTCTTATTTGTTTTATTTCGGCTAGAATAAAAGCAGTTCTTAATTTTTTAAGCTATTTTAAGGTCAATATTATTAGCCCCCTTAAGCATTATTTGTTTTCGATTGTCTACAGAACAAACCACTGTTATGCAATGACTTGCCTAATTAATCTAACTTCACCCTAATTGACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGAATACTAGTGTCTTGAAGAATATCTAGTCAAATATTATTTACTGTCATCATGACAAAGATAAAATAAATTAGTTATTAGAAATGAGTTATTAAAACTATTATGATCAGAAATGTGTTGAAATAAACGTATGTGGTCCTGCTGTGTGTTTGTGCTCAGGATGGATGCGCTCAGCCGGTGGTTCTGGAAGCAGGAGATCTGGCTTCCCCCA[G/T]GAATCGTCTGGGAGGATCTGGAGGAGATGCAGGGCTCTCGGCGTCCAATGCCCAGAGATCTGCTCCTCGCTCTGCCTCTCGCTCTGGCCTTCATCATGCTGCGCTACGCTTTTGAGAGGTAAATAACAACTTTAACACCTCCTCAGGGGCTTCAGGGAGATTTAGGCCCAATCCCAGTTCAATTTTTGTACCCCTACGCTTTCCCCTTGGCCCTTAAAACCGAGTGTGAAGGGCTTTAAAAATTACTTCTAAGAAATGAGACAGCACCGGCACACGTCTTCATATGTCAACGTGATCTTTTGCTTCATATGAGATTAGACGATGGCGTCTGCTGTAGTTATTCCAGTTGTGTTATCTTATTTATCTTCAGGAGATCACTGAAGGCATATATCATGTTATCATAATAGTATTGTAGGGATAATTTACAGTTTGACCCAAAGAATGACCAGTCTGGTAGATGAAGAAGAGCCGGAGTCAGAGATTTAAATAAATAAATCCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1656
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036240 Essential Splice Site 155 402 4 10
Genomic Location (Zv9):
Chromosome 2 (position 56582878)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 56245946
GRCz11 2 56369791
KASP Assay ID:
554-1603.1 (used for ordering genotyping assays)
KASP Sequence:
TTGCCTTCTACCTGGTGGCCTTCACCGCGGGACTGCTGTCTTTAATTAAC[G/A]TRAGTGTCGTTTCAAGCTTTATTCCTCAKGAGTCTTCATCTAATTACTGT
Long Flanking Sequence:
CTTAGTCCCTTTATTCGTTAGAGGTCGCCACAGCGGAATGAACCCCCAACTTATCCAGCATATATTTTACACAGAGGATGCCCTTCCAGCCGCAACCCAGTACTAGGAAATACCCATACACACTCATTCATACACTACAGCCAATTTAGTTAATCAAATCCCCTATAGCGCATGTGTTTGGAATGTAAGTAGCACACAGAGGAAACCCACGCCAACATGCGGAGAACATGCAAACTCCACACGGAAATGACAACTGGCCCAGCTCGAACCAGCGACTTTCTTGCTGTGAGGTGACAGTGCTAACATCAGTCATCGTACCTCCTTCTTGTCAATTTTGAAAAACATTTTTGATCCACTTCAAACATTGACTACTGTATAAAATGGATGTTTATTTAGCTATTTCCAGCACATTAACCAGATAATCCTCTGTGTTCCTCCTCAGCTGGAGGTTTGCCTTCTACCTGGTGGCCTTCACCGCGGGACTGCTGTCTTTAATTAAC[G/A]TGAGTGTCGTTTCAAGCTTTATTCCTCAGGAGTCTTCATCTAATTACTGTCGTTCAGAGGAGATGCTTTATTGAGGAGATCTGTGTTGTTTTCAGTGCACGCGTCTCTAATGAGGCTCTGAAACTCATCACAGGCCCTCGGGACACACTCCAAACAATACTACAGTGACTTAGACGAAATGCTCCAGTGTTTTTAAAACATAACTATAGTAAAGTGTATTATTCTGAATGTATTATCACCTTTATAAGTCGCTGTTAATGAATGCTCTATCTTACTGCAATATTAACTATAGTGTACTGATAAACTGTTACGAATATTGTTCTGTACTTTAGTTTAAACTACCTTAAACTGTGGTGTATTATAGCATAATATATTGAAAACTACAGTATTGGGTCATTTGTTTATGTCACTGTAGTGGGTGCGTTACTTTAGCAACTATAGAAATAACACAATAGATGAATTACTATAGTTGTTGTGTTACCATAGCAACTAGAGAATTA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa9557
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036240 Nonsense 172 402 5 10
Genomic Location (Zv9):
Chromosome 2 (position 56580089)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 56243157
GRCz11 2 56367002
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGACGGCCTGGTTCWGGGAWCAGARAGAGTGCTGGAGAGGGTTTCCTCGA[C/T]AGGTCAGATTAATGCACACAAACACATTCATTCATAAGAAACATACTAGC
Long Flanking Sequence:
TTGTCATGTTACCATAGCAACTAAAGAATTAGCACAACTACAATTACTGTAGTTGTCATGTTACCATAGCAACTAAAGAATTAGCACAACAGATCAATTACTGTAGTTGTCGTGTTACCATAGCAATTATAGAATTAGCACACATTAGATCAAGTACTATTGTTGTTGTGTTACCATAGCAGCTATAGCATTATCACTACAGATCAATTACTGCAGTTGTTGTGTTACCATAACAACTAAAGAATTAGCTCAACATGTCAATTACTATAGTTTTTGCATTACCATAGCAACTATAGAATCACCACAACACATTAATTGAAGTATTTACTATAGTATGGTTCAAAATCACTGCAGGATTTATTATAAGTCACTACAGTATTTTTTCATGAGGGTATCTGCACTTGTGTTACTGTGGGCTGTTTGTGGAGTGATGGTGTTTTTCTTCCTCACAGACGGCCTGGTTCTGGGATCAGAGAGAGTGCTGGAGAGGGTTTCCTCGA[C/T]AGGTCAGATTAATGCACACAAACACATTCATTCATAAGAAACATACTAGCAGACTAGTTAGTGTACTCTACTTCATGCAGCATACGTGGACCTAATAACTATTTAATCTTTTGATAACAAAAAGAAGAAAGTTGAGTTAAAAAATGTTTGTTTATTTCAGTTGAGGTTTATTAATATTACTAATTGTCATGACAGAGTAAACAAATTGAATGACCATATAATTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTTTGTTTATTGTGTTTATGTGTGTGTCTGCGTCTATCTATCTGTGTGTATGTGTGTTCAAAAATGTTTGTGCAAATGTGTTTATTTGTCTGTCTTTCTGTCTGTCTGTTTGTCTTTCTATCTGTCTGTCTGTCTTTCTATCTGTCTGTCTGTCTTTCCATCTGTCTGTCTGTCTGTCTGTGCTTGTATATATGTGTGTGTGTGTGCCTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25943
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036240 Essential Splice Site 282 402 8 10
Genomic Location (Zv9):
Chromosome 2 (position 56572680)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 56235748
GRCz11 2 56359593
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTTCGCTGCTGTTTTCCTGGTGACTCGACTGCTGGTGTTTCCTAGCAA[G/A]TGAGAGTTTGAAGTATTGATTTTCCATCTAAAACTATGAGAGTGTGTGTT
Long Flanking Sequence:
CATGTGTTTAGAGTGTGGGCTGTGGGGTAATCCGGAGCGCCCGGTAACATGGGGAGAACAATCAAAGTCCACACAGAAACGCCAACTGACCCAGCCGAGACTCAAACCAGTTACCTTCTTGCCATCGCGCCGCCTTAATTTATTTATTTTTCTTCATTTTTATTTTATTTTCTTCATTTTTATTTTATTTTATTTTGTTTTATTTTATTTTATTTTGTTTTATTTTATTTTATTTTTTTTTCACCACAGTGACCCTTATATGGAAGGGTATATGACACAAGTTAAAACTTTTTCTTTAATGTTTTATACAACAATACCCTAATAAAATTCCTTATTATAATGCCCTATGATCAACAGACTAAATGAACTGAACTCTTTTGCTGTTTTCTGCAGTCTGCCAAGATGTTTAACTACGCCGGCTGGAAGAAAACCTGCGACTCCTTATTTGTGATCTTCGCTGCTGTTTTCCTGGTGACTCGACTGCTGGTGTTTCCTAGCAA[G/A]TGAGAGTTTGAAGTATTGATTTTCCATCTAAAACTATGAGAGTGTGTGTTTGAGTATATAATACTGTGTGTGTTTTTGTGCTCAGGATCATCTACACCACTCTGGTTTTGTCGATGGAGGTGTTTGAGCCGTTTCTGGGTTATTATTTCTTCAATGCGTTGCTGTTGGTGCTGCAGGCGCTGCACATTTACTGGGCTTACTTAATCCTCAGGATGGTCTACAAGTTCCTCTTCTTGGGGAAAGTGAGTCAGATTATTATTATTTTGAATATTATTATTGTTATTATTATTATTATTACTGTTAATATTATTATTATTAATAATAATAATAATAATAATAAAAACAATAAAAACAATAATTTAGTATAATTATTATTAACCCTTTATTATTTTTTAATAATAAACTAATGATTATTATTATTAACCCATCATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTAATACTACTACTAATAATAATAA
Associated Phenotype:
Not determined