Busch Lab

ZMP

EIF4G3 (2 of 2)

Ensembl ID:
ENSDARG00000077215
Description:
eukaryotic translation initiation factor 4 gamma, 3 [Source:HGNC Symbol;Acc:3298]
Human Orthologue:
EIF4G3
Human Description:
eukaryotic translation initiation factor 4 gamma, 3 [Source:HGNC Symbol;Acc:3298]
Mouse Orthologue:
Eif4g3
Mouse Description:
eukaryotic translation initiation factor 4 gamma, 3 Gene [Source:MGI Symbol;Acc:MGI:1923935]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa38848 Nonsense Mutation detected in F1 DNA Not yet available
sa2588 Nonsense F2 line generated Not yet available
sa35102 Nonsense Mutation detected in F1 DNA Not yet available
sa27796 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38848
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111576 Nonsense 530 1561 10 31
Genomic Location (Zv9):
Chromosome 11 (position 28741715)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 27617701
GRCz11 11 27864875
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACTGCTCTGCTGGAGATGAGATGGTCTTGCAGTCAAGCTTAGGGACCTA[C/A]AGCAGCCCCTTTACAGTGCCTGAGCACCAGGAGAAGCACTCTGAAGAAAA
Long Flanking Sequence:
ATGTAATATAATATAATATAATGTAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATGTAATATAGTATAATAATATAATATAGTATAATAATAAAATATAATTATTTCTTAACATTTCATTATACTTTTTTAATTTGCTTGATTATTTTTCAGATTGAGCATTAAATGATACTAGTCCATCCACTTAATCGCCCTTAAATAATAGAAATGATTTACTTTTGTTTTGTCTTTTACCTTTAGTTTATAGATAGTTTAAATGTGATTGTTAATTATATTGGAAAGTAGGCGAACTCCCTCTGCATAGCGTAACAGCAACTAATGACATTGTTATCATGACACAAGTCATTATGCAGTAATTCATCTCGCATAACCCCTTGTGTAATGCTGCTTTTTTTGCGCTTCACATCAGGAGGAGACCTCAAAGGACTGCTCTGCTGGAGATGAGATGGTCTTGCAGTCAAGCTTAGGGACCTA[C/A]AGCAGCCCCTTTACAGTGCCTGAGCACCAGGAGAAGCACTCTGAAGAAAACGGTGAGACCGAGACAGAGCCTTTCAGGAACGGGGTTGAGACGGAGAGCACGGACAGTGGTGTGACGCTCGGGGACAGTAGGGGCTCCATGTGTTCCCCAACTCCACTCATTCAGGAAGGTAAGATTTCCCTCAGGAATTGGTTGGGGTTTCGTATAGCATGCTGAAAGTGTTTATTAAATGGTGAAAAAATCGAAATTAAAATCAAATCGAAAAGGTAGTTCACCCAAAAGTTTAAACACAAATAAAGATATTTTGAAGAATGTTGCAAACTGGTAGCCATTGACATTTATGAAATGAAAAAAAATACTGTAGCATTCCTCAATATCCTATTTAGTAAAATAAATTCATTATGAATTAATTGGAAACACTTGAGTGTGAGATTTATTTTTTATTTTTTTGGGTGAGCTATGCCATTAAGTCATTGTTTATTCAGACATTTTACTGATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2588
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111576 Nonsense 702 1561 13 31
Genomic Location (Zv9):
Chromosome 11 (position 28736270)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 27612256
GRCz11 11 27859430
KASP Assay ID:
554-2607.1 (used for ordering genotyping assays)
KASP Sequence:
ACCTGTCTGTCAGTGATGATGTTCAGCTCAAGAAGGCAGAAAATGCTTGG[A/T]AACCTGGGATGAAGAGAGAGGGTGTCGCAGAGGACCCAGAAACCATCAGA
Long Flanking Sequence:
TTCATGCCAAACTCTAATAATAAATTTAAAGAATAGAAAATATCTTATTCGTGCAGTAGTTAGTTGCTAAGCTTTTGTGAATTTTATATTTATTAGTGCTTTTAATTAATTTGACATTTAAAATGTTACTTAATCTTACACATCTTCTATTTTCTAATGTTTAATATATTTAATTATTTCAATATTTAAATTATTTATATGATTATTTTTCATATATAATATTCATAACATTATAATTATAAATGAAGTAATAAAAATAAAATCTATGTGAAGCTAATTACCTCTGAGCGCTCAAAACATTTATTCCATATCATGATGCAGCTAAATGTCATTTTATATTTATACATTATAAAACATGCAATTATTTTTAAAGTCATTACTTTTTTTGTACAACAATCTGTTAACAGCTTTTAAATGTGCGACGACTCCCACCACGCAAGATCATCGTAAACCTGTCTGTCAGTGATGATGTTCAGCTCAAGAAGGCAGAAAATGCTTGG[A/T]AACCTGGGATGAAGAGAGAGGGTGTCGCAGAGGACCCAGAAACCATCAGAACCCAGGTTTGGCCTCTAGAGCTTATATATCCATCATGAAACATCCACAGTAAAAGTAGCACTCAAGACAAGGTGCTTGTCAATTGTTTTGATCAGGATTTTTATTCATTTGTTTCAGCTACACAATTTAAGTCCTGATTTGTTAATGATGAAAATGTGTTTACTTTATTTGATGAACGTTTAGTTGATTTTACTACAATGTGTTGGCTATCTTTTGGCACTTCAGGAGTTGTTCCGGAAAGTTCGTAGCATTTTAAACAAGCTCACGCCGCAGATGTTTCATCAGCTGATGAAGCAAGTGACGGATCTTACTATCAACACAGAGGAGAGGCTTAAAGGAGTCATCGATCTTGTGTTTGAGAAGGCCATCGATGAGCCCAGCTTCTCTGTGGCCTACGCCAACATGTGTCGCTGCCTGGCCACGGTACGTTCCAAACACACTGCTTGCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35102
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111576 Nonsense 1194 1561 23 31
Genomic Location (Zv9):
Chromosome 11 (position 28717056)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 27593042
GRCz11 11 27840216
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATCAGAGACGCTGCTGGTCAGCGGTGTTTCAGAGAAGCCTGTCCTGTCT[G/T]AAGAGGAGATCGAGCGGAAGTCCAAAGCTATCATTGATGAATTTCTGCAC
Long Flanking Sequence:
CTGAAAACTACCACGTCATTTATTCCTTTAAGCTTTGTTTTTTCCGAGCGTATCTGAGTTCTGTTGCATGGTTGTGCTACATTGATTTATTTAACCACAACTGTTTATTAGGTGAAAGGTTTGATACTGATTGGAACTTGTAGTAGCGATGAGGTCTTAATTACCTTTAGGATTCAGGCGTATATCCTGTGAAGAATGTTGGGAAAAAAGCAGCCATTTAATTCCATAGTATATTTTGTACCTACTATGGATGTAGGTTGCACCTCCCCAACATTCTTCTGCAGATCTTTTTTTTTTTGTTGTTCAAAAAAAATTCATAAAAGTTTAGATCACTTGAGTTTGAGTAAATGTTGAGGGAATGTTTGGGTAAATGATGCTGACTTTTCCAAGTGTGCATTAACGTTTGTAAATATATATTGTAAATACTGAGCTTCTGCTTTATTGCAGTGAAATCAGAGACGCTGCTGGTCAGCGGTGTTTCAGAGAAGCCTGTCCTGTCT[G/T]AAGAGGAGATCGAGCGGAAGTCCAAAGCTATCATTGATGAATTTCTGCACATTAATGACTACAAGGTACAATGACCTGTATAAACAAGAACAAAAGCCACTCAACATTGACAATTAAAAACAAATGATTGTATATAATATTGTTCAAATGCTTCTGTTTAAAATCAGTACATTTTATATTGCAAGGATGTATTAAATTGATCAGAAAAATACATTAAATACATAAACTTTATAAAAAATATATTTAAAAAAATGTTTGATGGAACTTACTCTTCATCAATTAATCTTAGAGGAAAAACAAATTCCACAAAAATGTAAAGTTGAGCAATTGTTTTAATACTAATAATAAAGATAAATGCTTCTTGAGCACAAACGAATCATATTAGATGGATTTCTAAAGTATTGTGTGATTTAAAAAATTTAAGTTAGAAACTAAAAGAATGATTATTAAATTCATTCATTAAAAAGAAAAGAGATGAGCCATAATAATCTTGTTTTTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa27796
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111576 Nonsense 1534 1561 31 31
Genomic Location (Zv9):
Chromosome 11 (position 28706536)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 27582522
GRCz11 11 27829696
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCAGAGGACGCTTTCTATCAATGGGAGACGAGTAAAGACCCGACAGAG[C/T]AGCTGGGAAAAGGCGTAGCGCTGAAGTCTGTGAACGCTTTCTTCACCTGG
Long Flanking Sequence:
TTTGGACGAATCTCAGATGAGTTCTTCTCCTTTTTTGAGAGCTTTAATGACTGCTATATGTAAAGCAGCAGTTAAAGGTGAGCAAGCTACTCGCTTTTGAGCCTTTTATTAAACAAAACCCAACTCCTCTTCCTCACACCAGTCACTTTCATCTGTTTTTATTCTCTCTTCTCTAGATGAAAGCACGTCCTGTCGAGTGGACACTGCTATCATCCAGAAACGCCTGCCTATATTACATAAGTACTTCGACTCGGACACCGAGCGGCAGCTGCAAGCACTTTATGCTCTTCAGTCTCTGATTGTCGCCCTGGATCAACCACCCAGTACGTAGCCAATGAAAAAAATTAAGCCAGGTGACAGGAGGATTTGTTTGGATGGTCATTTTTGATTTGTTTTTTTCCGCAGACCTACTCCGGATGTTTTTCGATTGTCTCTACGATGAGGACGTCATTTCAGAGGACGCTTTCTATCAATGGGAGACGAGTAAAGACCCGACAGAG[C/T]AGCTGGGAAAAGGCGTAGCGCTGAAGTCTGTGAACGCTTTCTTCACCTGGTTACGTGAAGCCGAGGAAGAATCTGAGGATAATTGACATGAACTGCTGGCCGATGCTCGGAGGCCTCGTGCTGAAACACATAATAAAATCCATTCAGACTCTGCAAGTCTAGCCACATGGGAACTTTGAACCACTGGCCTATTTGAGCTGGAACTCTCTACGACATGGAGGGAACACTAAATACTTGTATTATATATATAGAAAATATTTTTGTTTTAAAGTTTGACTTTTTTTCTTTTCTTTTTTTTGTTACTTTTAAAAGAAGAGACTTAAAATAGGTTCTGAACTCTTTAATTTATTATTTTTTTAAGAGACTGCAAATATGGAGTTCTATTTAACATTTGCAGGCAAAAAGAACATTGATAGAAATAACAGAATAAACAGTGTATCATAACAGTAATATTAATTTTGTTTTAATGTGTCGGCAGCCTCCCTGGATTCACCTTAAAA
Associated Phenotype:
Not determined