ZMP
syk
Ensembl ID:
ZFIN ID:
Description:
tyrosine-protein kinase SYK [Source:RefSeq peptide;Acc:NP_998008]
Human Orthologue:
SYK
Human Description:
spleen tyrosine kinase [Source:HGNC Symbol;Acc:11491]
Mouse Orthologue:
Sykb
Mouse Description:
spleen tyrosine kinase Gene [Source:MGI Symbol;Acc:MGI:99515]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa2568 | Essential Splice Site | F2 line generated | Not yet available |
| sa34824 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa2568
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000005292 | Essential Splice Site | 414 | 585 | 9 | 13 |
| ENSDART00000141943 | Essential Splice Site | 414 | 585 | 7 | 11 |
Genomic Location (Zv9):
Chromosome 10 (position 5545373)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5541667 |
| GRCz11 | 10 | 5541971 |
KASP Assay ID:
554-3360.1 (used for ordering genotyping assays)
KASP Sequence:
TGGAGCTCGCTGAACTGGGGCCGCTTCACAAGTTTCTGCAGAAGAACAAG[T/A]ACGTCATGCTACAAATATGTAATGAGACTTGAGATACTGTGCTGTTATGA
Long Flanking Sequence:
TACGCCAGAACAAGATTATAGTTCCTGGACATATCAGCCTATAAAATAGCAACGTTTCATTTTCGGTTGGTCTACACAATGTAACCAGAGAAGAGTCAAGCTTTAATTTTCTTTTTTGGATTTTTTGAGTGAGATGCTAATGGTCTAATCTATGCTAAGCTAAGTTCAAAGTGCCACTGCCTGACTAAAAAAATTGGCTTAATGGGTTCTAAATGTTTTTATTTTCAAAAATTAACTGAGTGTTTCTTTCAGACACATTTTAAGAGTGTATGTGGTTTGTTTACTTCAGAACACAGAAGGTTGTTGCTGTTAAGATCCTAAAGAATGATGACGATAATGCAGCAGTAAAGGACGAGATGTTGCGGGAGGCGAACGTCATGCAGCAGCTGGATAATCCATACATAGTCCGCATGATTGGGATCTGTGAAGCGGAAAACCTTATGCTGGTTATGGAGCTCGCTGAACTGGGGCCGCTTCACAAGTTTCTGCAGAAGAACAAG[T/A]ACGTCATGCTACAAATATGTAATGAGACTTGAGATACTGTGCTGTTATGAATATGGTGATGGCTAAAGATCTTTTTTAAAGACTTACAGTTAATTTACTCAACCTCAGGTCATCCAAGATGTAGCTGACTTTTTTTCTTCAGTAGCACGTTATAGATTTCTTAACTAAATTTGTGATTCTTGGCGATTTGTAAAAAAGCAGTTAATGGTTAATGTCTTTTTAGATTATTATATATATATATATAGTTTATTTTAGAATTATTAGCTCCCTGTTTCTAGACATAATAGTTTTAGTAACTCATTTCTAATAACAGATTTGTTTTATCTTTAAAATTATGACAGTAAACAATAGTTGACTAGATATTTTTCAAGTCACTTCTTTATAGCTTAAAGTGACATTTAAAGGCTTAACTTGGTTAATTAGGTTAACTAGGCAGGTTAGGTATATTAGGCAAGTTAATGATGGTTTGTTTTGTAGACGATCGAAAAAATGGAAGATTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34824
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000005292 | Nonsense | 552 | 585 | 12 | 13 |
| ENSDART00000141943 | Nonsense | 552 | 585 | 10 | 11 |
Genomic Location (Zv9):
Chromosome 10 (position 5541662)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5537956 |
| GRCz11 | 10 | 5538260 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGAACGGACAGCGGATGTCCGCACCGCCCGACTGCCCACCTGAGATGTA[C/A]GACCTCATGAAGAAATGCTGGACATACAAGTAAGTCAACGTTTACTAGAA
Long Flanking Sequence:
AGTGTACACATCTTATGATGGCAGCAGGATATGATTTCCAGCAGAAATAAGTCATAAAGCGTAAATCATCTCAGACCAGTTTCTTAAACATGACAGTGAGTTCACTGAACTCAAATAGCCTCCACAGTCACCAGATCACAATCCAGTAGAGGACTTTGGGATGTGGTGGAATGGGAGATTCGCATCATAGATGTGCTGCCGACACATCTGCAGCAACTGCGTGATGCTATCATGTCAATATGGACCAAAATATTCTCAGGAATATTTCCAGTGCCTTGCTGAATCTATGCCATGAAGACAGTTCTGAGGGCAAAAAAGGGTCCAGTCTGGTACTAGTAACGTGTACCTAATAAAGTGGCCGGCGAGTGTATAATAGCAAAGATGCTCATGTTGGTTTATTCATCTTATCTTTTGTAGGGCATGAAGGGAAATGAAGTCATCCAAATGATTGAGAACGGACAGCGGATGTCCGCACCGCCCGACTGCCCACCTGAGATGTA[C/A]GACCTCATGAAGAAATGCTGGACATACAAGTAAGTCAACGTTTACTAGAAAAACCATGGGTTAATACCATTCTGAACATCACTTTTAATTTTGAGGGAAGCAACATTTTACAGTTATAATTCAGTAGCAGTGTTAGCATCATTGCTTTTACTGGGTTATTAAACAGGATAGGGCGACGTAGGTAGGTAGTGCTGTCGCCTCACAGCAAGAAGGTCGCTGGGTTGCTGGTTCGATCCTCGGCTCAGTTGGCGTTTCTGTGTGGAGTTTGCATGTTCTCCCTGTATTTGCATGGGTTTCCTCCGGGTGCTCTGGTTTCCACCACAGTCCAAAGACATGCTGTACAGGTGAATTGGGTAGGCTAAATTGTCCATAGTGTATGAGTGTGTGTGTGAACGTGTGTGTGTGTGGATGTTTCCCAGAGATGGGTTGCGGCTGGAAGGGCATCTTCGCTGCGTAAAAATGTGCTGGATAAGTTGACGGTTCATTCCGCTGTGGCGACC
Associated Phenotype:
Not determined