ZMP
si:ch211-215h6.2
Ensembl ID:
ZFIN ID:
Description:
Im:7149356 protein [Source:UniProtKB/TrEMBL;Acc:Q58EH2]
Human Orthologue:
E2F8
Human Description:
E2F transcription factor 8 [Source:HGNC Symbol;Acc:24727]
Mouse Orthologue:
E2f8
Mouse Description:
E2F transcription factor 8 Gene [Source:MGI Symbol;Acc:MGI:1922038]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa25357 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa34023 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa34022 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa40850 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa25357
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079953 | Nonsense | 50 | 932 | 3 | 14 |
| ENSDART00000128488 | Nonsense | 35 | 917 | 2 | 13 |
| ENSDART00000131726 | None | None | 236 | None | 4 |
| ENSDART00000134548 | Nonsense | 45 | 239 | 2 | 4 |
| ENSDART00000144118 | Nonsense | 35 | 203 | 3 | 5 |
Genomic Location (Zv9):
Chromosome 7 (position 17371942)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 16344731 |
| GRCz11 | 7 | 16596704 |
KASP Assay ID:
554-7461.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACAACATGATGTGTTTTCAATATAACAGGGGCATGTTTTTGTGGAGCCA[C/T]AAACGCCACTAAAAAACTCAAATAAAGCTTCAACATCTGAAGCTGCTCTA
Long Flanking Sequence:
TCGATGGAACGCTTGTCAGTTATTGCTAAGCGCAAAATAATAAACACTTATTTCAAATCATAATATTTGTTATTGATTTACGTGCATTGATTTGCATCTGTTGAGTTATAAAATACATTTTTAGCAAAGCGTTAAAATTTATAACCGACACTGATCTTCGCAATGTTGTCTCCAACAATGTATAATGCTGTAAAAAAACGGTGGGACTGGTTTAACGTAATAAATGTTACAAATGATGTTAGTCAACGTTGATTGACGTAACGTTGCCTCATGTGTTGTGTGTTTAGGTGGAAAATGTCCAGTACATTATCAGAAGGTCAAACATTAATCAAGAAATCTTTAAGTCCATCAAAGGCAACATCTACAAATAACAAGGTGAGTTATTTTAACATAACAGGTCATTTTGTAGTGAGCAAAATATTGACTTGATGAATAGTGTGATTATAGTTATACAACATGATGTGTTTTCAATATAACAGGGGCATGTTTTTGTGGAGCCA[C/T]AAACGCCACTAAAAAACTCAAATAAAGCTTCAACATCTGAAGCTGCTCTACCGGAGACCCTTAAAATCATGGGGCCCCTGACAACGCCTACTAAGGTCCTAGATGCACCTTCAAGCGACCCTTGGACACCCACTTCTAACCTAAAAATGCTTATCAGTGCAGCCAGTCCTGAGATCCGCAACCGCGAGAAAGAACGTGCCGTGGACAGCAGCGAATCCGAGAACTCACAGGTATCCGAAAAAGTCATTTTATTAATGTTGTAGTTCAGTGGTCCTCAAACTTTTTTCATCAAGTACCACCTCAGAAAAAAAAATAGTCTCTCCAAGTACCACTGTAATAAGCAGTATTGAAATACAGTGGCGTAGTAAGCCCAGTAAAGCAGCTACAGTTCTGCATAGTTTAAAAACGTGGCAGATTAATTCCTATCATTAAAAATTTTTATTATTGTCAGTGACTTCAAACAGTCTGAATGTTAACACTGTACTGTGCTTATATGTAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34023
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079953 | Nonsense | 232 | 932 | 5 | 14 |
| ENSDART00000128488 | Nonsense | 217 | 917 | 4 | 13 |
| ENSDART00000131726 | None | None | 236 | None | 4 |
| ENSDART00000134548 | Nonsense | 227 | 239 | 4 | 4 |
| ENSDART00000144118 | None | None | 203 | None | 5 |
Genomic Location (Zv9):
Chromosome 7 (position 17368309)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 16341098 |
| GRCz11 | 7 | 16593071 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGACGCTTGCTGTGCTGAAACGGGCCGGAAAAGAGAACCGCTATGAA[C/T]AGCTTATGCAGCAGATCCGACAAAGGAGTCAAGAGCGAGAAGAGAGAGAG
Long Flanking Sequence:
GACATCCAAAATATGTACTGTTGGTGTGCCTTCGGGAACAGAGTTGGGAAACGGTGAACTAGTGGATTATTACCTGCTTATAAATAAGACATTGGCTGCTTATTAGTACCTAAATACATATTATGCATGATCTTATTCTACATTCCTAATCCTACCTTATACCTAAACACAAATTGTACCTAATAACTATTAATAATAAGTAAATTATAAGTTTATTAAGCTTAAACTCATAGTTAAGGGTTTGTTAATAGCGAAAGTTGTATCTAAAAATAAAATGTGGCCCATGAAATACATTTTTTTTTCCATCAATCCTAATTGTATCCTTGCTCATTTTCCTCTCAGACGTGGAAAGACGTCGCATCTACGACATCATGAATGTCCTTGAAAGCCTTAACATGGTCAGCCGGCTGGCAAAGAATCGCTACACTTGGCATGGTCGAGTAAAACTTGCACAGACGCTTGCTGTGCTGAAACGGGCCGGAAAAGAGAACCGCTATGAA[C/T]AGCTTATGCAGCAGATCCGACAAAGGAGTCAAGAGCGAGAAGAGAGAGAGTTCGATTTGGATGGAGAGGAGAAGGAGAATGAAGAAATGTCCAGTTTTGAAGTTGACGGAGACTCTGGGCTGGCGGATCTTCCAGGAGCGGATTCTAAAGCAGGTAACGACTTGTTTGTTTTTAGTTTTAGGCTCTAGTAGTGTCTACGCATCTCATACATACTTGCATGAACTGGATTGTGTTTCTATGCTAATTTATGTAATGATTCATCAAATCATCAGTAGGGCTGTGCGATATTGCAGAAGCTTGCAGGGTTCATACGGGTGCTGGAAATCCTGGAAAATGCTTGATTTCTAAAATAGTGTTTTTAAAATTAGAAAAGTGCTTGGATTTTGCACAAAGTGCTTGAACGTGCTTGAATTTGAAATTGCGACCGTTTTGGTGGCATATGCGCCAGATATTTCACCCATGTCTTTGGACTGTGGGGGAAACCGGAGCACCCAGAGGAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34022
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079953 | Essential Splice Site | 382 | 932 | 7 | 14 |
| ENSDART00000128488 | Essential Splice Site | 367 | 917 | 6 | 13 |
| ENSDART00000131726 | None | None | 236 | None | 4 |
| ENSDART00000134548 | None | None | 239 | None | 4 |
| ENSDART00000144118 | None | None | 203 | None | 5 |
Genomic Location (Zv9):
Chromosome 7 (position 17364732)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 16337521 |
| GRCz11 | 7 | 16589494 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAGCCTGCTTTCAAATGGACTGGGCCAGAAGACATACCATCTCCAAAGG[G/A]TAAGCATTAAAGCATGTTTCACATGAAATCTGACCTGTTCATAATCCTAT
Long Flanking Sequence:
GGCCGAAGTTTTCAGAAAGTTTTGGATTCAGTCACACGATACTCCGGTGTCGTGCGGACAAACTGTGAAACCATGTAGAAGAAGATACAGTTTTAAAAATACCCAAACATCTGAAATGACAGAGTACTGAACCAAACATTTTTTTCTCCTGTTCTATTGTCTAATAAATTATTGAGTGCAGACCATTTTTGCTGCTTATTATTTAAGAAACTTTGGTCCTAACGCCAAACCCTGGAAGAGCACTGATTTATATTTGATTAAAGACAGAGTTCAAAGACTCGTAATTAATTTTTACTCATCATTTTTAGCAAAATCATTTTTTGAGTAAAATGAAAACTGATTACTGAACTTTCTGTTTGCAGCCAAGATCCGTAGACTTTATGACATTGCGAATGTTTTGAGCAGCCTAGAGCTGATTAAGAAAGTGCACGTGACTGAAGATAAAGGAAGAAAGCCTGCTTTCAAATGGACTGGGCCAGAAGACATACCATCTCCAAAGG[G/A]TAAGCATTAAAGCATGTTTCACATGAAATCTGACCTGTTCATAATCCTATTCAGACTTGAATGTTTATTTTAAAGCTTGTGTTGACTTTGTATATTTGTTTGTTTAACAGATCTGGAGATCTCCACTACATCCTCAGCACCAAAGCCTCTCGAGTCTCGTTCCTCTGTTGAAAACTGTGCTAAAAATCTGTTTTCCTCCCCTGGAACAAAGCGAGGTTTTACCCGCCATCATTCTCTAGTCAAGCTGGTTAAGAGCATTCAGGATGACCGCAGGAAAATCAACTCTGCGCCTTCTAGTCCAATTAAAATGACAGGTGAGCTATTTTTGTCATTTCATTGTTAGCAAGCCATCAGCTGTCTGACCGTCATCTGTTTTCTGTGGGGATTTTCTACTTCAGACTTTGAATGGTTGTTTGGTCAATCGCTATTAATAATACCAGTCTTAAAGGGCCATGAAACCCCCTCGTTTCAGCAGGGTGTTTTTACACCTCTACTTTGGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40850
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079953 | Nonsense | 706 | 932 | 11 | 14 |
| ENSDART00000128488 | Nonsense | 691 | 917 | 10 | 13 |
| ENSDART00000131726 | Nonsense | 63 | 236 | 1 | 4 |
| ENSDART00000134548 | None | None | 239 | None | 4 |
| ENSDART00000144118 | None | None | 203 | None | 5 |
Genomic Location (Zv9):
Chromosome 7 (position 17357239)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 16330028 |
| GRCz11 | 7 | 16582001 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGAGAAGAGCCAGACCTCAGACAATGAGGCAGGACTGACCCCTGTAAGA[C/T]AACCACATTCACAGCCCCAGAAGCTCAGCGCTCCCTTTCAGGACATGGTG
Long Flanking Sequence:
AAAAAAAAAAATCTCTTCACAGTACCTTTCGATTAAAATGAAAATAATAATAATAAAATATAAAACGTGTATATTTGTGAATTCTGTTTACATGAATATATTTTATACTATTAACTATTACTTTTGTACATAAATTAAGCATTTGAACTGCCATTTAAAAAAAAAACATTACCTTAAATCTCAAGTTAACCATTCAGCACCTTCATTTTATATATTGATACTACTTGCACTAACCGTTCCAGCCTTCTGGTGTTTCATTTCAGAGCGTTTCTCCAAAGCTGTGTGAGATTCTACAAGCACGTCTGAAGGCCCGTAGAGGAGCTTTGACCTCCAACCGCCCTTCCGCAAGAGCTCTTCATCTGGAGTTCTCCAAACCCTCTGAAAGCCAGCCAACGGTACAAACCGGCACAGCATCTCTGGAGCACAGCCTGGAGACCTTTCTAGAGAAGGAGGAGAAGAGCCAGACCTCAGACAATGAGGCAGGACTGACCCCTGTAAGA[C/T]AACCACATTCACAGCCCCAGAAGCTCAGCGCTCCCTTTCAGGACATGGTGCTGCCATCTGGACCCATACACACAGAGGTAGGAAGAACACCACACATATGTATGCATCTTGCTGAGATCATGAGACAGACCTTTGACTAATTGTTCTTGTTCCCATTAGACATTGATCCCCGCGGGTTATTTGATTCCCATCTCTCAGCAGTCCATTGTGAACTTCAGAGAACCGCAGTGCTCCAATGAAAGCTCCAAAGCCTCCACACCAACATACAACATCTATCACACACCAACAGCAGGTATGCTAGTGATCAAAGAGGCTCTTGTTAAAAAAAAAAACATGTTTTCTTCATCACAGGGTACATTTATTTTTAGTGGGAATCTCTTCAGAGATGGGTTTAGGCCAGAATAACACCATTTTTATTTTTTTATTTTAATAACTAAAATAGTATAAAACAAAAGTACAAGCAGACATGTCTAACCCCCTTACCCAGAACTTCAAGAGTT
Associated Phenotype:
Not determined