Busch Lab

ZMP

ythdc1

Ensembl ID:
ENSDARG00000051953
ZFIN ID:
ZDB-GENE-041114-114
Description:
YTH domain-containing protein 1 [Source:RefSeq peptide;Acc:NP_001007411]
Human Orthologue:
YTHDC1
Human Description:
YTH domain containing 1 [Source:HGNC Symbol;Acc:30626]
Mouse Orthologue:
Ythdc1
Mouse Description:
YTH domain containing 1 Gene [Source:MGI Symbol;Acc:MGI:2443713]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa25322 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13549 Nonsense Available for shipment Available now
sa40610 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa38531 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa14642 Essential Splice Site Available for shipment Available now
sa20594 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa25322
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073671 Essential Splice Site 9 679 1 16

The following transcripts of ENSDARG00000051953 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 72908732)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 69106328
GRCz11 5 69878880
KASP Assay ID:
554-7394.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTAAATCCACGCGGGGCTCAAGATGTCCGTCGACAGGAGAGACGAGAAAG[G/T]TAAACGATCACATTTGTGTCCACAGATTCACTAACAAAGGATTTTGTTTG
Long Flanking Sequence:
GCATCAAAAACTGTCGTTAAACTTTTTAGGGAGAAATGACGTCACAAACGGGACAGGCTTCGATTGGATGTGGTGATTTTATAAGTTTCACACATTTAAATTAATATTGTATACGTACAAATTATTATCCAGTGATCTAGAATTATATTTTTTTAAAGTCCATGTTTATTTACATTTGACATGTGGCTACAATAAGTGACAAAGAAACTATTCAGACATGAGTTATTTGTCCGAAGCGTGTGGTCAATAACAAAGGCGTGTGATTTCCTCTGAGTATTTGGCAACCCTCATGCGGGAGAAAGGCAATCCGCCATTTTGAAGCAGACGAATACACCGTGACCACCAAACATTTAGTGCTCTGTAAGATTTTCAGACATAACTATTAATAAATAGTGTTATTAAGAACAAAGTGAGAGAGAGAGAAAGCGAGAGGAGGGCCTTTAAAGTGTGTTAAATCCACGCGGGGCTCAAGATGTCCGTCGACAGGAGAGACGAGAAAG[G/T]TAAACGATCACATTTGTGTCCACAGATTCACTAACAAAGGATTTTGTTTGGTTATAAAATAAATAATTAGCCATTACTCATTAACCAAGCTTTCAAAAAGTCATTCACGTTGTTTTTAAAAATATGTAACGTTATTGTTAATGTTTTGCATACCGTCGATAAGTAGTTAGCTTAGCATGATGCTAACGCATGTTTTCATGGAGGTTATTTGTTTATATTAATCTATTTACTTGAGAAATGTCATTATTTTGTTTTTATAAACGTCAAGTGATATTTCTATTTATTTTATTTGTGTGTATAAGAGATGTATTTCAAGTTTAGATCTTATATAAAGCACATTATGTAACCTCACCAGGATTTGAAGCACAACAACAATGGATGATTTTCTACTAGAGAAGAATCATAGCATTTGCATGTTGTTTACATCGATTCGAAGTTTTATAATACACAGCACGTGTGTAAAAACACAGTATATCCCGCTGTGTATTGTGTCAGTATCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13549
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073671 Nonsense 98 679 3 16

The following transcripts of ENSDARG00000051953 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 72910584)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 69108180
GRCz11 5 69880732
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGTAAAAAGACCAGCAATCCCAGAGGAAGACACGCACCAGAAGAKCTATA[T/A]GATGACAGAAAGAACCATTCTGGAAGAGGAGGTGCGTCTCGGGCTGATCT
Long Flanking Sequence:
GTCAGTCTTGGTACACAATTTAACTACAGAAGAGTCGAGCTTTACATAAGAAAATTATCTGAACTGTTTTTTTTTTTTTTTTGAGTGAGTGAGATGCTAATGGTCTAATCCGATTCAATGATCTATGCTAAGCTAAGCTAAAAGTGCACCAGCCGGCGATCATCTGAATGCATTGAAAACTCATAACAAACAGCTGTTTAACTCTGCGACTTATAACATGAGCTTATTTCCAGATTAGTTGAGTGTCCCTTTAAAGAATTTTTCTGTGTCTAGTAAAAATCCATTTTCTGGAGAAAAGTGTTTCCACATTAACCGGTTGTTTACTTTAACGTCTCAGGGTCTAAAAGGAAGCACGATCGAGGGGATGCTCAGGATGCGAAGCGCCTGCGAGCTTCAGGACACAACACCAGACAACCAATGAAAAGAGCTGCTCCTTCTTCTGGGTCAAACGGTAAAAAGACCAGCAATCCCAGAGGAAGACACGCACCAGAAGATCTATA[T/A]GATGACAGAAAGAACCATTCTGGAAGAGGAGGTGCGTCTCGGGCTGATCTGTCGAAAGGATATGGTGAAAAAGGCCTGTCCAGCAGCAGAGACTCACAGAGACGGATCAAACCATTGATGCCTGAGCTGACAGAGGTAAGACAATAGATATTGTGCACCCATACATTCTCTACTTGTTTCAGAATTGTTTGAGTTTCTTTTTTCTGTGATGGGAGGCAGCAACAATAGACTTTCATAGAGTTTTTGTTCCTACTGTTGATTGTCAATGGCTTTCACTTTCCAACATTCTTCAAAATATCATCTTTTGTGTTCAATAGAAAAAGTAAGCTAATTAAGATTGGAAACACTTTAGGGTTTAATGGTTTACTCACGATTGAGTTAACAACCAGTGAGTAAATGTTCATTTTTGGGTGAACTACCCCTTTAACTATTCCCATAGGGCAGATATGTCAAACTCAATTCCTGGAGGGCCGCAGCCCTGCACAGTTTAGTTCCAACCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40610
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073671 Essential Splice Site 394 679 None 16

The following transcripts of ENSDARG00000051953 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 72921142)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 69118738
GRCz11 5 69891290
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAATGCCAAGATGCTTGGAGGGGTCTTTAAAATTGACTGGATTTGCAGG[T/C]ATAAAATCAAGAGCGCGTTCACGTCTGGCTTTTGTTTGTTGTTTACTGTT
Long Flanking Sequence:
TCTCAAACTCAAGTCCTGGAGAGCCGGAGCTCTGCATAAATTAGTTCAACCACCTCCAACTCACACCTGCTTAATAGTATCTAGTGGTCTTGAACATCTTTATTAGTTGGATTAGCTGTGTTTGATAAGGGTTGGAGCAAAACTGCAGAGTTGCGGCCCTCCAGGAATCCAGTTTGAGACCTATGTTCTGTAATGACTATGGCATTTTACTATGTATTGATTTTATTAAGATCCACTTGCCAAACTTGAATTCATGTCCACATTTTTAGTTATTATTCTATATATATATATGCATTGACTTTATCTTTTCACTGAATAAATGTGAATTAATTTCACATGGCTTGATTTATGTTCATGTACTCATTTGTGTTTATGTTTCAGGTTTTGCACGGCTGTCCTCAGAGTCTCATCATGGAGGATCTCCCATACACTGGGTTTTGCCTGCAGGCATGAATGCCAAGATGCTTGGAGGGGTCTTTAAAATTGACTGGATTTGCAGG[T/C]ATAAAATCAAGAGCGCGTTCACGTCTGGCTTTTGTTTGTTGTTTACTGTTATTGATTTTTTGAGGTTTGTTTTCATTCTGCTTGAAGGCGGGAATTACCTTTCACCAAAACGGCTCATCTTGCTAACCCATGGAATGAGCACAAGCCTGTGAAGATCGGACGTGACGGACAGGTTAGCTGTTTAAACTCCTTCCATAACCCAGGGGTGTAACTGTCACATTCAGTGGGACAATTAGCGTGATTTAATAATAATTAAATTGCAAAGTTGTGATCGACATGCACATCTTGTCAGAAAAGCACGGTTTTGCGATCAGAAATAAATAAACCGAAGGCCAGAGGGCGTTCTTGTGCGAAGAAGATGCCATGAAGATTAGATTTATGGAGATGCAAACTTTTCAGTGTGTTTGCAGTTTTCACTTTGAGGTCTGCTGCGCTCGTGCATCCAGGTTAATCATGAACAACTCGGTGCGCATGCGCTAGTTGTACTATCGCGGTCTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38531
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073671 Essential Splice Site 422 679 9 16

The following transcripts of ENSDARG00000051953 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 72921315)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 69118911
GRCz11 5 69891463
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTAACCCATGGAATGAGCACAAGCCTGTGAAGATCGGACGTGACGGACAG[G/A]TTAGCTGTTTAAACTCCTTCCATAACCCAGGGGTGTAACTGTCACATTCA
Long Flanking Sequence:
TTGAGACCTATGTTCTGTAATGACTATGGCATTTTACTATGTATTGATTTTATTAAGATCCACTTGCCAAACTTGAATTCATGTCCACATTTTTAGTTATTATTCTATATATATATATGCATTGACTTTATCTTTTCACTGAATAAATGTGAATTAATTTCACATGGCTTGATTTATGTTCATGTACTCATTTGTGTTTATGTTTCAGGTTTTGCACGGCTGTCCTCAGAGTCTCATCATGGAGGATCTCCCATACACTGGGTTTTGCCTGCAGGCATGAATGCCAAGATGCTTGGAGGGGTCTTTAAAATTGACTGGATTTGCAGGTATAAAATCAAGAGCGCGTTCACGTCTGGCTTTTGTTTGTTGTTTACTGTTATTGATTTTTTGAGGTTTGTTTTCATTCTGCTTGAAGGCGGGAATTACCTTTCACCAAAACGGCTCATCTTGCTAACCCATGGAATGAGCACAAGCCTGTGAAGATCGGACGTGACGGACAG[G/A]TTAGCTGTTTAAACTCCTTCCATAACCCAGGGGTGTAACTGTCACATTCAGTGGGACAATTAGCGTGATTTAATAATAATTAAATTGCAAAGTTGTGATCGACATGCACATCTTGTCAGAAAAGCACGGTTTTGCGATCAGAAATAAATAAACCGAAGGCCAGAGGGCGTTCTTGTGCGAAGAAGATGCCATGAAGATTAGATTTATGGAGATGCAAACTTTTCAGTGTGTTTGCAGTTTTCACTTTGAGGTCTGCTGCGCTCGTGCATCCAGGTTAATCATGAACAACTCGGTGCGCATGCGCTAGTTGTACTATCGCGGTCTGATTATGTTTCAATCAAGGTTTGTATGCATCAAATACATAACATCTGTGCCAAACATTTAAACTGACGAACATATTAACAATAATACAAGCGTATAGCCGAATTAAATGTATGCATTGGCATGTTACAGCCTTAGGCCGTACTCACACTAGGTACAGTTGCCTCAAACTGGGCCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14642
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073671 Essential Splice Site 606 679 None 16

The following transcripts of ENSDARG00000051953 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 72930848)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 69128444
GRCz11 5 69900996
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCCCGCTTCAGGGAAAAGAGGGTYGTCCGCTCTTTCGCCTCCAGTTTGG[T/C]AATGATTTGCCTCTTAAARCACACTCAGATACTGCCTGCAAGGCATCAGA
Long Flanking Sequence:
CACCACCTTGGCAAGGAATGGTAAGATTGAATTATATTGAATAAAACTAAATTTGATGTGTATTTTGGTTCAGTTTTGATTATGATTTGGGTTTACGTTGTACAAATAAAAAAGAAATCCCTCTTGCAACACTTAAATACCATTTAAAAATACCATACATGAGTTATTTTCAAGCCTGTGTATTGTCATTTCAGTCTTTTGGTATTAATAAATAATAATGATTGATCAATTTTGGCCTTTTCACTTCAGTCTCCATCAAGCTGACTGTAAAAATATTGGTTGTGGTTTATACAATATCTTGCAGCTCTTATAGTAACACTCTAATATGTTTGATGTGAAGGCCCCATACCCTGGTATGGAGCATCCTCCTCAGCACCCGTATTACCAGCACCACCCTCCTCCACCCCAGGCCCACCCGCCTTACTCTGGACACCACCCCATGCCCCATGATGCCCGCTTCAGGGAAAAGAGGGTTGTCCGCTCTTTCGCCTCCAGTTTGG[T/C]AATGATTTGCCTCTTAAAGCACACTCAGATACTGCCTGCAAGGCATCAGATACGACTGATATTATTGCATGTTTGCTGATGAAGCTGCAAACTGTGTAGCTGCCTCTGATATGCTTGATGATGCTTTACATTTACTGTAGCATTATCTTGCTGTTCATTTAAATTAATGTGTTTTATTTATAAATACACAAGTCAAAAGTAATGACGTCAATAAAAAGTGTATAACTACATCTACTATGAATTGTTGTACCTTCTGACTGCTACATATTATAGTTTTTATATTAATGTATATGTTAGAGTTAAAAATATTAATATTGTTATGAATTATATATTTTATGTTCAGTATTTTTGGATTTATATAATTATTTATTAATAAGAGAACACTTTGTACTTATTACCTGGCGATTTATTATAATGTTTTAAAAATTGAAGTGCAATATGTCAGCATTGTCAATTTTGTAAAATGTTTGTGAATTATTAATTGTTATTTATGTGAATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20594
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073671 Nonsense 650 679 16 16

The following transcripts of ENSDARG00000051953 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 72932753)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 69130349
GRCz11 5 69902901
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGAGACCGTCAGAGAGAGCGTGACCGACCCAGAGACGGACGGAGAGAC[C/T]GAGAGCGAGAACGTGGACGGGAGCGGGACCGCGAGAGAGAGAGAATTCGA
Long Flanking Sequence:
TCTATTGGATTGAGATCTGGCGACTGTGCAGGCCATTAGTACAGTGAACTCATTATCATGTTCAAGAAGCCAGTCTGAGATGATTCACGCTTTGACATGGCGGGTTATCCTGCCGGAAGTAGCTGTCAGAAGATGGAGATACTGTGCTTATAAAGGGATGGAAGGATGGATGTAGGCTTGACCACGTCTACATGCCTAAATGCATTGAGTTGCTGCCATGTGATTGGCTGGTTAGAAATGTGTGTTAACAGAGTTCGACAGGTGTATCTAATAAAGTGGCCGGTGAATGTCTTTCACTCATTTAGGTTCTACTGAATGATGTGTTTGGTGATGTTCATCATGCTCATTCTTTTGCATTTATTTTTTTCTAGCATGATTACGACATGCGCGTGGATGATTTTCTAAGGCGAACGCAGGCAGTGGTGAGCGGACGCAGAAGCAGACCGCGGGAGAGAGACCGTCAGAGAGAGCGTGACCGACCCAGAGACGGACGGAGAGAC[C/T]GAGAGCGAGAACGTGGACGGGAGCGGGACCGCGAGAGAGAGAGAATTCGAGACCGCGAGAGAGAAAAGGAGAGAGGCCGATACCGGAGATAGGGGGGAAACACTTCACTTTTATTCCCTTTTTTATTAATCACTTTGTAGATAGTGTTTATTTCATTTATCTGTTTTTTTTATATATATATATAAATAGTTAAAGGGATAGTTCACCCATAAAAACTCTGTTTACTTGTTTCAAACCTCAAACTTTCTTCTGTGGAAGATATTTTGAAGAATGCTGGAAACCGGTAACCATTGACTTCTATTGTAGGAAAAGCACATACCATGGAAGTCAATAGTTACAGATTTTCAGCTTAAATGTCATTTTTTGTGTGTTTTACAGACGTCAAAGTGCAAATAAATGCTTCTACTTAGATTTTTAGTCGTTTCTAATCCAAATATCTACAAAATAAATGAATAAACATTTTCTAAACAAGCTAAAAATTGTCGTTTTATGAAATAATA
Associated Phenotype:
Not determined