ZMP

pycrl

Ensembl ID:

ENSDARG00000015236

ZFIN ID:

ZDB-GENE-041014-244

Description:

Pyrroline-5-carboxylate reductase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q5SPD7]

Human Orthologue:

PYCRL

Human Description:

pyrroline-5-carboxylate reductase-like [Source:HGNC Symbol;Acc:25846]

Mouse Orthologue:

Pycrl

Mouse Description:

pyrroline-5-carboxylate reductase-like Gene [Source:MGI Symbol;Acc:MGI:1913444]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa16640	Essential Splice Site	Available for shipment	Available now
sa25147	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa16640

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000002787	Essential Splice Site	41	288	2	7

Genomic Location (Zv9):

Chromosome 20 (position 52870930)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	20	52723777
GRCz11	20	52529393

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GGAGCGGGAAACATGGCGTYTGGCGTCGCGCAGGGAATCATCGCCTCAGG[T/G]CAACAAATACCYGACAGTACMTTAAATARCTGCATTATATCAACAGTTCY

Long Flanking Sequence:

TACTCCTTACCTCGTCTAATTCTTCTTTCCATGGATCAGGAATTACAGCAACACTGATCTGCTGGATATATTGTTGACGTTGTGTGTTGTATCTTGCTCCAGTCCAGCAGATGTCAGCAGTGTACATGCTATAGTTTCGAGTCTGTACTGTAAGTCCTGAAGAAAATGCCATCCATGTGAGAAGAGTTTACAAATTAAACAGGGATCAAGTTAACAATTTAGCTGCTGCTGCTGCGTCTTTATCAAACTTACCATGAGTCTGTCAGGTGCTTCAGACAAGACCAGCGATTCACCCGTGAGTAGGTTTTGTTGACCATATACTATATTAACCTGCTGATTAAATGTTGTTTAGTGAACAGATGTCAGCAGCAGCATCTCCAGTATTATGATTGTGAAATAAAATGTCTGTTGTGAATTCAGGATGTGTTTCAGATTAAGATCGGATTCATCGGAGCGGGAAACATGGCGTTTGGCGTCGCGCAGGGAATCATCGCCTCAGG[T/G]CAACAAATACCTGACAGTACCTTAAATAACTGCATTATATCAACAGTTCTGTTTATAAAGTGTCTAGTATCATGTCAAGTACATTCAGTAGGAAAAAAATATAACAGTAGTTTAATTTATAACAAACCTACGTGCTTTTGAACCTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTTTTTTTTTTTTTTTTTTCCATATTTTAATCGTATAATATGTTGTATTAGGCCTGTTGTTTTGTTCATTTCTGCACTGACAGCTCGAAAGAAAGATTTACATTGATCTGAGTTCATCTGCTATGTCTCTCTATAATTTAAGCCTATAATGCAGAATTCTAGCCAACGTTTCTTTTATAGATTGATTAATTCAATAGATCGATTTTTACAAAACCTGACAATTGAAATGAGGCTTTGTATATATGAGAAAGTCTGACCTCTGCTTTATATTCGGTGACGATGTCTGTGAGTTGTTA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa25147

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000002787	Nonsense	93	288	4	7

Genomic Location (Zv9):

Chromosome 20 (position 52874590)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	20	52727437
GRCz11	20	52533053

KASP Assay ID:

554-7367.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTGGAGGCTCTCGTTTGATCTTTCTGGCTGTCAAACCTCACATCATTCCA[C/T]AAGTCCTAAAAGAAATCTCACAGGAAGTCACCAAGGAACACATCATCGTT

Long Flanking Sequence:

CTTTCAAGAAAAGTATAACAATTTCTCAACAAATAACTATTTCATTATTCTGCTGTTAAGCATAACACATGTGATCATCCTCACTTACCTAAAAGAGTAAAGTTTTAGTCACATTAACATCTGACTTTTTTAAATGGTGATGTGCCTTTTTATACAGTGTATGTAAACTTCTGCTTTCAACTGTGTATATATAAAAGTAGCACAAGTGATGACACCAAATAATACTCCATTTGGCTTTACTTACAAACAGCAAACAACAAAGATTAAAAATATTTGATATTTTAATGTTTAGAAAACAAAAGCACACCTGACATTTTTAAATGGATAAAGTTTAGAACATTTGTAGTTTATGAGATCTTGTATCCATATTTCTGCAGTATTGTAACAGGTTTGTGTTGATGCTCCTACAGGAGAAAGGTGTTTCAGTCACTCATTCCAATCATGAGGTTGTTGGAGGCTCTCGTTTGATCTTTCTGGCTGTCAAACCTCACATCATTCCA[C/T]AAGTCCTAAAAGAAATCTCACAGGAAGTCACCAAGGAACACATCATCGTTTCCATGGCTGCCGGAATCACTATAGCAACACTCGAGGAGGTGACCATTTACATACTTTCACTTTTTATGTTTTATGTAAATTGATAGTTATCCTTACACTTTATTGTTTTGTTTGAATTCATACAGTGAAATCAAAATTATTTTACACCTTCAACATTTCTCACATTATCACAGTTTGTTAATTGTATTTTATTCTATGGTTGCCACTGTAACAGCAACTAATTGTATGGCTGTATTCTGTTCTATAGTTGCTACAGTAACACAGTGACCATAGTTGTATGGCCGTGTTCTATTTTATAGTTGCTACGGCAACACAGTGACTATAATTGTATGGCTGTGTTCCTTTTTATAGTTGCTACGGTAGCACAGCGACTATAGTTGTAAGGCTGTGTTCTGTTCTATAGTTGCTACGGTAACACGGCGACTATAGTTGTATGGCTGTGTTCTGTT

Associated Phenotype:

Not determined