Busch Lab

ZMP

tmc4

Ensembl ID:
ENSDARG00000031757
ZFIN ID:
ZDB-GENE-030131-7489
Human Orthologue:
TMC4
Human Description:
transmembrane channel-like 4 [Source:HGNC Symbol;Acc:22998]
Mouse Orthologue:
Tmc4
Mouse Description:
transmembrane channel-like gene family 4 Gene [Source:MGI Symbol;Acc:MGI:2669035]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa42763 Nonsense Mutation detected in F1 DNA Not yet available
sa17316 Nonsense Available for shipment Available now
sa15301 Nonsense Available for shipment Available now
sa25020 Nonsense Mutation detected in F1 DNA Not yet available
sa36188 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa9506 Nonsense Available for shipment Available now
sa18068 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa42763
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Nonsense 39 732 2 16
Genomic Location (Zv9):
Chromosome 16 (position 34348275)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32079775
GRCz11 16 32033805
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCACCATTCCCTGAGGTTACGGACAGTTGCGGCTCCGGCTCCTGCTCAG[C/T]AGAGCAGCGGAGTTCAGTTTGACTGGGCTTCTCCTCCTCCTGAAGATGCT
Long Flanking Sequence:
GATTTTTCCTTTACCAAACTTGACTGATTTCCGTGAGAATCTTGGGTCCATGTGGGTTACAGTAGGTCTCCTGCAGTAAAATCTACCTTCTGCCACTTTTCTAAATGGTCAACTAGAAGTCAAGTTATTATTTGTTGCTCTAACAAGCAAAAAAAAAAAAAAGTGTTGCTACTTGTTTAAACTACTTGAGCTGAAATAACACAATTTTTTTTTTTTTTGTTTTTCGAGGACAACTTAATTGTTTTATGTTCAATCTAATTTGTATAAACAGTTTGGTTAACTTAATTGACTTGTGTTGGGACAACATGAAGGACTTGTGTGGAACCCAACATTTTTACAGTGAATAAGTCATGTTGCAACTATCCACGCTCTCCTCTGTCATACTTTGTAAAAGTGATTGCTTTCAAAAACATGTGTTTTCACCATCAGACTACCCTAGTCCCGATGTCTCCCACCATTCCCTGAGGTTACGGACAGTTGCGGCTCCGGCTCCTGCTCAG[C/T]AGAGCAGCGGAGTTCAGTTTGACTGGGCTTCTCCTCCTCCTGAAGATGCTGAAGACTCCAGTGAAACACGTAACCTTCGCGAGCTGCCGCTGCACATGAGTCTAAAGAGAGCAGTAAGGTAGACATCCATTATCTTCTTACAGCAACCAACTTTTACATTATCAAAACTGGAATGGAAAGGGAACAGTTAGTCTATTTCTCTGTCCAACGAATTTCTGACAGAAATAATCACAGAAATTCAGTTAAGAAAGTTTTCATATACAGTTGAAGTCAGAAATATTAGACTTCCTGTGTTGTTAGCCCACCCTGTATATATTATTTACATTCTGTTTAATGGAAAGGAGATTTTTTTCAACACATTTATAAACATGATCGTTTTAATAACTCATTTCTTATAACTGATTTATTTTGTCTTTGCCATGATGACAATCAATAATATTTACTAGATATTCTTCAGGATGCTACTATTCAGCTTAAAGTGACAATTAAAGGCTTAACTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17316
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Nonsense 152 732 4 16
Genomic Location (Zv9):
Chromosome 16 (position 34350787)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32082287
GRCz11 16 32036317
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTTCTATTCCTGAGATTTCTGGTGATTCTCAACTTTCTGTCCTCTTTGT[T/A]AATCGCAGCGTTTGTGCTCATTCCCAGCATTGTGTTTCGCTCCTTGAACT
Long Flanking Sequence:
ATGTGGGAAATATAAAAAAAAAAGAATCAAACGTAAGCTAATAATTCTGACTTTGACCTATATGTTTTGTAAAATACAGCAATTTAAATATAGAACATTTTAATTAAAGACAATCAATAAATTGTGAATAATTTACTGCCTTTGTCTGAATGTAAACAATAAAAATGAACTGTAACCCGAGTTTGAGTTTTTCAAAACATGATAAAATCTATTACATATCATTTTTATGACCCAGCACTGTATAAACTATGCACAAAGATATAAAAGTGTTTAATTAAAAACATATGCTGTTCTCATTTAGTACACTGCTCGTCTAGTAAAAGAAGCTCTGGAACATGATAAAATGAAGTTAATAGCAACAATCAAACTAAATGTATTCTCATTTCCCCTTCATTTCCCCTTCCCACTTGTTTTGCTCATAGGTCACTTTGGTGGAGGAGTCCAGTCCTACTTTCTATTCCTGAGATTTCTGGTGATTCTCAACTTTCTGTCCTCTTTGT[T/A]AATCGCAGCGTTTGTGCTCATTCCCAGCATTGTGTTTCGCTCCTTGAACTTCAACTCCACCTCCAACATCACTATAGTCAACACAACAGGTAGGAACACAGTCTCCCTCCCAGACACAAACACAAAGACTGTCACACGTCAGTGCCTCTAATGGGAAGATTCTTGCCGTTTACCGGATACCACAATCCTCTTTGTTTGGCCTGAGATCATTTTGAGTATTCATGAAACCAGCAAAACCAGTCTGGCAACATCCATCTATTTATACTTTACAAAGTCTTTCAAATAAATTAAAAAAACAACAGCACTTATGGCATGTTTTGTTCTGAACCATCGGTTGATCTGGTTAATAATTCATTTCAGTAACTAATCATTAAAAGATAAATCACTTTACAAAGAATTTGACTATTGTGGTTAACAGATTAAATTAGATAATTTCTTCCTTGTTCTAGTAAGTTTTCATTATGTTGAGCAAAATTGATTCTTGCAGTTTGTGATAGTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15301
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Nonsense 255 732 6 16
Genomic Location (Zv9):
Chromosome 16 (position 34353472)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32084972
GRCz11 16 32039002
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGGCCTACCTGTTGACWGCAGCTTTCTACTTCCTCTTCTGCTTCTTTTG[T/A]ATAAYTATTAGGTGAGTCAGCTTTTGTCAGAGTTGTTAGAACATTGCTST
Long Flanking Sequence:
CTTAACTTAACTTAACTTAACTTAACTTAACTTAACTTAACTTAACTTTAAATGCAAAAATATAACTGATCCCAGACTTTAAATGGTAATGTAAGTGAACTGTATTAAATATGTAGCATTGTCAGCATTTTAGATGCCAGCTTTTACAATTGCTCAACAGCTCTTACAATTTTACAATTATACAACCTTTTCATTTAAACTTAAATGTAAATCAAATTAAAATAAAATGCACAATGTTTTTTTTTACAAAATGTATGCTACAGAAACTACTGTTCCAAGTTTATTTATTCTGACATGTAAGCTGTTTCTTTGTCGGTGAATTATTGCATAATGATCATTACTCATCAATGTCATCTCCTCCATCAGGGTTTTATGGAATATTCATACCTTTTTTATGGCTATTATAATAATACAATGATTGAAAGCGATGGCTTCTCTTACAACATCCCTCTGGCCTACCTGTTGACAGCAGCTTTCTACTTCCTCTTCTGCTTCTTTTG[T/A]ATAATTATTAGGTGAGTCAGCTTTTGTCAGAGTTGTTAGAACATTGCTGTAGAATTAAACTGACGTCTCTGTCTGTCCAACAGAATGGGTGGTACGGCTCGTGTTGTTGTAGAGACGGGTGCAGGAGCAGCCGGGGGTTACTGTATGCTGGTGTTTACAGGATGGGATCACGGTCTTCAAGGAGACCGCGCTGTAAAGCTTAAACAAAACAACGTTCGCTACAGGTTACAGGTCTGTACATGGGAAACCAAAACTAGAAATGAAATGCCCTGAGGTATTTTTTGATGGAATATGGATTGGATCTGCTTAACATTCAACTATCTAATATTTTACCAAATGGATAAAACAAAACATTACAAAATGACAATCTTCAAAGGTGATTTTTGCTATATGATAAGTCTGCTGAGAGGGCCGGTTCTTTTTTTTTCAAAATGTGGACGTTTTTGCAGTTACTCACCTCATTTTCTATTTAACTACAATGTTTAAATATATCATTTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25020
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Nonsense 427 732 10 16
Genomic Location (Zv9):
Chromosome 16 (position 34358001)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32089501
GRCz11 16 32043531
KASP Assay ID:
554-7544.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGTTGTAGGGCAGTGTTCTTGCGTTTGGTCAGTTTGGGTGTTTTGCTGTA[C/A]ACTCTATGGGAGCAGATAACCTGTAAAGGAGAGATTGGCAGTGATGACTG
Long Flanking Sequence:
TCTCTTTTTGACTCCTAAGTCTATGAAAACAACAGGATTTACGGGGCTACTGCTGCAGTACTTACCCTCCATGGTCATAACAGCAAGCAATTTTGTGGTGCCTTTACTCTGTGACAAGATTGCATTACTGGAAAAGTATTCCCCCAGTACCACGGTCATCCTAGCCTTGCTCAGGTTTGATCAACACTTGCATCCGCACTGAATGAAGATATCAAAGAGAACAAACAACAGAAATATAATAAGCACTTCTTGTTTAACCTTTGTTAGAGCCCTCGATGAGAGCTCTTTGCAGACCTTCATTAAATAGCTTACAAAAAGATGATTTTAAATGAAACCATGTCATATTCTCTTAACACTCACGCATTGTTCATCCATCCACCGCTCTCTTTGATTTGGTCTTTGTTGTAATTCTATTTTCTGCTCTTGCAATGCTGCTTATTCTCTGTTGTTCGTTGTAGGGCAGTGTTCTTGCGTTTGGTCAGTTTGGGTGTTTTGCTGTA[C/A]ACTCTATGGGAGCAGATAACCTGTAAAGGAGAGATTGGCAGTGATGACTGTAAACTCTGCGGTTATTATTATAACCAATACAAGGTAAACGAAATGTGCACTTATTCATTAATTGTTCAGATCAGATACGCTACCACTAGTTAGCATAAAAAGTCATTGTATAAAAATGGTTTGTTCTTCAGACAATCGAAAAAAATTATACTTAAAAGTGCTAATAATACTGACTTTAAAATGGTGTTAAAAATATTAAAATCTAATTTTGGTATTGCCAAAATAAAACAAATAAGAAGAAAAAATATTATAGGAAATACTGTGTAAATGTCCTTGCTCTGTTAAACGACATTTGGGACATATTTGAAAAAAAACAATTCATAGCAGGGCTAATCATTTTGACTTCACATATTATATTGTAATAAATATTTATATATTATAGTAAATGTCAATAAAGTTACCATATAAAGTCCATATAAAGGATTACATTGTTTGAATTTTAATGCTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36188
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Essential Splice Site 549 732 12 16
Genomic Location (Zv9):
Chromosome 16 (position 34360247)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32091747
GRCz11 16 32045777
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCCATTTATCAACACCCTCAAATTCGTCATCTTTTATTATTGCAAAAAG[G/A]TACCATGAGCACATCCTTCTCAGATGCACATATAAGTTTTTCAGTCATCT
Long Flanking Sequence:
GAGAAATGAAGAACTTCACACTTTTGAATAGTTTAAGTTTTAGGATTGATATCTTAGTGGTTATTGCCAAAAGTCTCACATTTTTGCAATTTTAGAAATGATTTTAGGTTCAATCCTTCTTTCAATCCTTCTGTTTAGTGCTGGGAGACGCGAGTTGGCCAGGAAATGTATAAATTAACTTTATTTGACTTCCTGATTACCGTTGCTACACTGATCCTGGTAGAGTTTCCACGCAGGTATGTTTCTTTCTTTTGTGTGTGTTGGTTCATACAAGTATTTAGTTAAATATCTAAGTCTGTTACTTTTATATGTTCAGGATCGTGGTGGATCATTGCTCATGCAAACTGAGCCAGCTGGTGGGACGGCAAGAGTTTCTGGTTGCCCCGAATGTTCTTGCTCTCGTTTACAGTCAAACGGTGGTTTGGACTGGAGCTCTTTTCTGTCCATTGCTGCCATTTATCAACACCCTCAAATTCGTCATCTTTTATTATTGCAAAAAG[G/A]TACCATGAGCACATCCTTCTCAGATGCACATATAAGTTTTTCAGTCATCTGCAGTCATTTTTCTTGCTTGTGTCAGATTACTCTCTTCCAAAACTGTCAACCGGCAACAAGAAACTTCAGATCCACCACCTCCAACTTCTTCTTTTTGTTGGTTCTGCTCTTTGGATGGATGTTGGCCAGTGTGGTTCTGCTTTACAGTGTTGCTAAGTGAGTGATTCTCCTCCATAAATGTTGGGAAATATTTCCATCTTCTATGACATCACTGTAAAACCTCAACTTTTGGTTCTTCCTACTGTATGTCAAGATTTATGATGAGTCTGTTTTAGGATCCATCCATCATATGGCTGCGGCCCTTTCCGTCTTGACCCAACTATGTGGGATGCTGTACCACAAGCTGTTAACATGCTAAGCACCACTAGTAGAGCTTTCCTGTTTTACATCGGCTCCCAGAAATGCTCTATTCCACTCTTCATCTTCTCTTGGTTTGTATAAACAGCCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9506
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Nonsense 573 732 13 16
Genomic Location (Zv9):
Chromosome 16 (position 34360394)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32091894
GRCz11 16 32045924
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCAACCGGCAACAAGAAACTTCAGATCCACCACCTCCAAYTTCTTCTTTY[T/A]GTTGGTTCTGCTCTTTGGATGGATGTTGGCCAGTGTGGTTCTGCTTTACA
Long Flanking Sequence:
ACGCGAGTTGGCCAGGAAATGTATAAATTAACTTTATTTGACTTCCTGATTACCGTTGCTACACTGATCCTGGTAGAGTTTCCACGCAGGTATGTTTCTTTCTTTTGTGTGTGTTGGTTCATACAAGTATTTAGTTAAATATCTAAGTCTGTTACTTTTATATGTTCAGGATCGTGGTGGATCATTGCTCATGCAAACTGAGCCAGCTGGTGGGACGGCAAGAGTTTCTGGTTGCCCCGAATGTTCTTGCTCTCGTTTACAGTCAAACGGTGGTTTGGACTGGAGCTCTTTTCTGTCCATTGCTGCCATTTATCAACACCCTCAAATTCGTCATCTTTTATTATTGCAAAAAGGTACCATGAGCACATCCTTCTCAGATGCACATATAAGTTTTTCAGTCATCTGCAGTCATTTTTCTTGCTTGTGTCAGATTACTCTCTTCCAAAACTGTCAACCGGCAACAAGAAACTTCAGATCCACCACCTCCAACTTCTTCTTTT[T/A]GTTGGTTCTGCTCTTTGGATGGATGTTGGCCAGTGTGGTTCTGCTTTACAGTGTTGCTAAGTGAGTGATTCTCCTCCATAAATGTTGGGAAATATTTCCATCTTCTATGACATCACTGTAAAACCTCAACTTTTGGTTCTTCCTACTGTATGTCAAGATTTATGATGAGTCTGTTTTAGGATCCATCCATCATATGGCTGCGGCCCTTTCCGTCTTGACCCAACTATGTGGGATGCTGTACCACAAGCTGTTAACATGCTAAGCACCACTAGTAGAGCTTTCCTGTTTTACATCGGCTCCCAGAAATGCTCTATTCCACTCTTCATCTTCTCTTGGTTTGTATAAACAGCCCTGCTACATACACTGCTGGTCAAAAGTTTGGGGTCAGTAGGATTTTTAAATGTTTTAAAATAAGCTTATCCTGCTCACCAAGGCTGCATATATATCATCAAAAATACAGTACAAATTGTACAATTGTGAAATTTCATTGCACTATAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18068
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041054 Essential Splice Site 593 732 13 16
Genomic Location (Zv9):
Chromosome 16 (position 34360455)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 32091955
GRCz11 16 32045985
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCTTTGGATGGATGTTGGCCAGTGTGGTTCTGCTTTACAGTGTTGCTAA[G/A]TGAGTGATTCTCCTCCATAAATGTTGGGAAATATTTYCATCTTCTATGRC
Long Flanking Sequence:
CACTGATCCTGGTAGAGTTTCCACGCAGGTATGTTTCTTTCTTTTGTGTGTGTTGGTTCATACAAGTATTTAGTTAAATATCTAAGTCTGTTACTTTTATATGTTCAGGATCGTGGTGGATCATTGCTCATGCAAACTGAGCCAGCTGGTGGGACGGCAAGAGTTTCTGGTTGCCCCGAATGTTCTTGCTCTCGTTTACAGTCAAACGGTGGTTTGGACTGGAGCTCTTTTCTGTCCATTGCTGCCATTTATCAACACCCTCAAATTCGTCATCTTTTATTATTGCAAAAAGGTACCATGAGCACATCCTTCTCAGATGCACATATAAGTTTTTCAGTCATCTGCAGTCATTTTTCTTGCTTGTGTCAGATTACTCTCTTCCAAAACTGTCAACCGGCAACAAGAAACTTCAGATCCACCACCTCCAACTTCTTCTTTTTGTTGGTTCTGCTCTTTGGATGGATGTTGGCCAGTGTGGTTCTGCTTTACAGTGTTGCTAA[G/A]TGAGTGATTCTCCTCCATAAATGTTGGGAAATATTTCCATCTTCTATGACATCACTGTAAAACCTCAACTTTTGGTTCTTCCTACTGTATGTCAAGATTTATGATGAGTCTGTTTTAGGATCCATCCATCATATGGCTGCGGCCCTTTCCGTCTTGACCCAACTATGTGGGATGCTGTACCACAAGCTGTTAACATGCTAAGCACCACTAGTAGAGCTTTCCTGTTTTACATCGGCTCCCAGAAATGCTCTATTCCACTCTTCATCTTCTCTTGGTTTGTATAAACAGCCCTGCTACATACACTGCTGGTCAAAAGTTTGGGGTCAGTAGGATTTTTAAATGTTTTAAAATAAGCTTATCCTGCTCACCAAGGCTGCATATATATCATCAAAAATACAGTACAAATTGTACAATTGTGAAATTTCATTGCACTATAAAATAACTGTTCAAAAGTAGATTATAATTGAGTTTATTAATGTATTCCAGTGATTTTAATCATG
Associated Phenotype:
Not determined