ZMP

zgc:153332

Ensembl ID:

ENSDARG00000062418

ZFIN ID:

ZDB-GENE-060929-608

Description:

tubulin--tyrosine ligase [Source:RefSeq peptide;Acc:NP_001070093]

Human Orthologue:

TTL

Human Description:

tubulin tyrosine ligase [Source:HGNC Symbol;Acc:21586]

Mouse Orthologue:

Ttl

Mouse Description:

tubulin tyrosine ligase Gene [Source:MGI Symbol;Acc:MGI:1916987]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa24929	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa18309	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa24929

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000090273	Essential Splice Site	161	307	3	5
ENSDART00000123869	Essential Splice Site	161	404	3	7
ENSDART00000142732	Essential Splice Site	157	400	3	7

Genomic Location (Zv9):

Chromosome 13 (position 15879571)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	15794604
GRCz11	13	15925596

KASP Assay ID:

554-7374.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGTGGAGATGGGACAGTGTGGATAGCCAAATCATCAGCAGGCGCAAAAGG[T/A]AAAAAATCTCTGTTGATCCAAAAGACTGTTAAGATATAAACAAAGTTTTT

Long Flanking Sequence:

TTTTTTGAGAGGTCAGTCTCTGGTCTGCATATGTCGAAGAATTTATATGCACAATTTATGCACGCATACGCTTGGCACAGAAGTATAAATCAGACTTAAGTGGAGCATGAATAAATGACAGAATTTAATTTAATCTCTTTAATGTTTTGTTAAGTGAGGAATGTCTTCAAATTGTACTGGGGTTTCCTCATGTGGTTTATTTTCATCAATTTATAGTTTGTTAACCTTGGGAATAATATTTATCTTGTAATATTTTTGATGTTTAGGATTATCAAGACCAGTCCAGAGTTGAAGGACTCCTGTAACTGGTTTCCTGAGTCCTACATCATATACCCAACCAACCTCAACACCCCGGTGGCCCCGGCCACCAACGGCATCAGCCACATGAAGAGCAACCCAAAGACAGATGAGCGAGAAGTCTTCTTAGCATCTTATAACTCCAGAAAGGAAAGTGGAGATGGGACAGTGTGGATAGCCAAATCATCAGCAGGCGCAAAAGG[T/A]AAAAAATCTCTGTTGATCCAAAAGACTGTTAAGATATAAACAAAGTTTTTAATGGGTATTTTGGGTCATATGGATCATTATTTTCATCACAGCATTTGAAAATGAAAGGCAACTTAAAGCAAATTATCTTCAGCAGACCACAAATAACTTCAAAAATTTGAGACCGTTTCAGAGCAATGTTATGGCCATGTTGATTATTTTTGTATTATTGGGCAGTGGTGTTCAACCATGTTCCAGAGAGACCACCAGCACTGCATGTTTTTGATGTTTCCTTTGTCACAACTATTTTAGGTCTTTTAGTCTCCACTTTCGAGCTGATGATCTGAATCAGGGGTGTTTGGTTAAGGAGACATGGATAATCTGCAGAGCTGGTGGTCCAAGAATGTGGTTGAGAAACACAGTTATAGGAAATACAAAGAGCAAAACAATCTAGATTAACAAAAATTAACAGCTTTTTTTTCTAAATTGGATTAATTTGCATGGATTAGATGTTCATAATA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa18309

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000090273	Nonsense	248	307	5	5
ENSDART00000123869	Nonsense	248	404	5	7
ENSDART00000142732	Nonsense	244	400	5	7

Genomic Location (Zv9):

Chromosome 13 (position 15878605)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	15793638
GRCz11	13	15924630

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TACAACAGCTCAGATCTYCAGAATATGACCAGTCATCTGACAAACCACTG[T/A]ATTCAGAAAGAGCATTCGCARAACTATGGCCKAWATGAGGAGGGCAATGA

Long Flanking Sequence:

TTGGATTAATTTGCATGGATTAGATGTTCATAATAAAACACAATTGTGCGCTAACAAAATAAACACTACAAATGTTTATATTATGTGGACTTAAATGTTATTTTATTGAAAAAAATAATCCATCATTTATTAGTATGTTAATGTCCCTATCTATGTTCAGGTGCTGGCATTTTGATTTCTCATGACGCAAACCAGTTGCTGGAGTTCATTGATAATCAAGGCCAAGTGCATGTCATTCAGAAGTATCTGGAGAAACCTCTGCTGCTTGAGCCAGGTCATCGCAAATTCGATATAAGGTAAGATGAGCCTTTAAGATGATGGGAGAGCATACAAATGCAATGTGTCGTCCTAATGCTGGATGTTCTTTTATGCAGAAGTTGGGTGCTTGTGGACCATCAGTACAACATCTACCTGTACCGTGAGGGTGTGCTGAGGACATCGTCTGAGCCCTACAACAGCTCAGATCTCCAGAATATGACCAGTCATCTGACAAACCACTG[T/A]ATTCAGAAAGAGCATTCGCAGAACTATGGCCGATATGAGGAGGGCAATGAAATGTTTTTTGATGAGTTTAAACAGTACCTGCTGAACACACACAATCTGGCTATGGAGACCTCTATTTTACCTCAGATCAAGCATATAATCAGGTGCTCATTTACAAAAAAAAGTTTATTTTCGCCATGAAAAAAGATGGAATTTCATGTTTTTGTGCCTATGAATGGGTTACATTAAAGGTGCACTAAGCAATATTAAAAAAATACTTTTGAATACACTGTTTCACTGGGTCGCAAAACAGAATTATAACAGCACTCAGCATTTATACAGCACTCAGAATTATAACAGCATTATAACAAAATTCGCTTGGTGTACCTTTAATACACATGTAGGAAATGTAGCTTACCTAATGTTTCAAAAGCTAATGAATTGGGGTTTTTTTGTGCTAGAGATTTAATAGTCTACCAGTTCAAAATCATAAAAATCTGTTTATATTTTGCATTTGCTTA

Associated Phenotype:

Not determined