Busch Lab

ZMP

mapkapk2a

Ensembl ID:
ENSDARG00000002552
ZFIN ID:
ZDB-GENE-030131-5532
Description:
MAP kinase-activated protein kinase 2 [Source:RefSeq peptide;Acc:NP_958460]
Human Orthologue:
MAPKAPK2
Human Description:
mitogen-activated protein kinase-activated protein kinase 2 [Source:HGNC Symbol;Acc:6887]
Mouse Orthologue:
Mapkapk2
Mouse Description:
MAP kinase-activated protein kinase 2 Gene [Source:MGI Symbol;Acc:MGI:109298]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa11786 Nonsense Available for shipment Available now
sa24891 Nonsense Mutation detected in F1 DNA Not yet available
sa13320 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa11786
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027532 Nonsense 2 382 1 10
Genomic Location (Zv9):
Chromosome 11 (position 22050918)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 21057149
GRCz11 11 21217717
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGAAGTAGKTAGCAGTTTTAAGTACGAGAAKAAAAGAGGTGGGAGATGT[T/A]GACTAACGCCAACAGTCCGCCRAAGTTTCCAAACCAACAGCAGCARCAAC
Long Flanking Sequence:
TAGGCCGCGGCTCCTTTAAGAGCGCAGGCATTCCTATCCCCGACATGACGTCAGAGCAGCAAGACGCTGGCCGAAAGTCGCGAAGGGGCAGTGCGCGTCTCACAGAGGACTGGTGTTCTAGCGCATGCTATTCTCGACTATTTAACTCAACATTTGTGTTTTTAATTCGCCCGGCGGCTCTTTCGGATAGCCGGTGACACTTCGACGACGTTTAACCTTGAAGCGAGTTCATGTAAGTCGCCTTTTTAACTCTCTGAACCCTGAATCAGTGGATTGACCCTCGACATGGATATTAGCTAGCTTAGCTAGTCACCAAGAAACCGAAATAACGGCGCGACAGAGGGTTTGTCTTACAGTTTTATCGCTTTTAAACTCGTTTATGTACCTGGAGCCTAGCTCACTGAGGCAAATATTGGCCTTGGGTGTTGCCAAAGAAAGACTAAAGTTCGGAAGAAGTAGTTAGCAGTTTTAAGTACGAGAAGAAAAGAGGTGGGAGATGT[T/A]GACTAACGCCAACAGTCCGCCGAAGTTTCCAAACCAACAGCAGCAACAACAACAGCAAAATCCACCTCAGTTCATGCTGGGAAAAGGATCGCTTCAGATCAAGAAAAATGCCATTACCGACGACTACAAGATCACTAACCAGGTGCTGGGACTGGGCATCAATGGCAGAGTGCTAGAGATCTTTTACAAGAGGAGTGGAGAGAAGCTCGCTTTAAAGGTAAGAATGAGACGTTCATCAATCTAACTTACTTTTGTACTTCGATTAAACAGGTGAGGTCAAACTAGTTCTGTGTTCATATACAGTGACTAAAACAAACTTAATAATTAATTTCTGGCGATTTAAAACCACCAGCTTTACGTTCTGACATTCATTCATTCAGCCAGTGTTTTATTTATTTATTTTAATGTGTAGTGTGTTTCAGCGTTATCCATGTAAGGGATTTAAAAGTAATCAGGTAAGCTTTCTGCAGGTGTTCTTCTAGGGTACACACAGTGATTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24891
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027532 Nonsense 235 382 6 10
Genomic Location (Zv9):
Chromosome 11 (position 21991796)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 20998027
GRCz11 11 21158595
KASP Assay ID:
554-7444.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAGTATGACAAGTCCTGTGACATGTGGTCTTTGGGTGTCATCATGTA[T/A]ATTCTGTAAGTGAATTTGTCTCATGTGTTTTGCTTGCTTGCATCATTTTG
Long Flanking Sequence:
ATTATTTTTTTTGCCAATTTGTTGTTTGTTGTCTGTACAGAGGCTTCTGATATTATGAAGAGCATAGGAGAGGCCATTCAGTATTTACATGCGATAAACATCGCACACAGAGACGTTAAGGTATGAGTTTTAAAATGACTTTTTTTTTATTTGTTTTTTTTTGTCCTTAACTAATTATGTCTGAAAACTCACTTTGCAGCCAGAGAACCTTTTATATACCTCTAAAAGGCCAAACGCCCTTCTCAAACTGACAGACTTCGGATTTGCAAAGGAGACCACCACACACAACTCTCTGGCCACCCCCTGCTATACTCCTTATTATGTTGGTAAGAATATCAGAATCATTGAAACTTAAGTGTCAGTATTTAGATTCGTTCCCACTCATGAAACTTTTCCATTGTTAAGTATTTTCATCTTTTCCATGTTATAGCCCCAGAGGTGCTTGGTCCAGAAAAGTATGACAAGTCCTGTGACATGTGGTCTTTGGGTGTCATCATGTA[T/A]ATTCTGTAAGTGAATTTGTCTCATGTGTTTTGCTTGCTTGCATCATTTTGTTACTGTCTGGGCCTCTGTTTTAATGCTTTTCTCACTCCTGACCGTAGAAAATCTGTCTGATAGAGCTCAATTCTCACTTTATTCAACCTCCAGACTCTGCGGTTACCCTCCTTTCTATTCGAATCATGGATTGGCAATATCTCCTGGTATGAAGAAACGAATCCGAATGGGACAGTATGAGTTTCCAAATCCTGAGTGGTCGGAAGTGTCAGAGGAAGGTATATGTCAAGTTCCTGTTTTCTGAAAGAGACTTGAGAAACCGTTCCTAGAATGCTGTTATCTCAAGTATTGAAGTTTTGCACATTTCTAAGAATGATTATAGATTTGAATGACTCATTCTTCTTATTTATAGCCAAGCAGCTTATCAGAACATTACTGAAAACGGAGCCAACACAGAGGATGACCATAACAGAGTTTATGAACCACCCTTGGATCAATGTGAGTGTCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13320
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027532 Nonsense 348 382 10 10
Genomic Location (Zv9):
Chromosome 11 (position 21989694)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 20995925
GRCz11 11 21156493
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTTTACAGGAGGAAATGACTAGTGCCTTGGCAACRATGAGAGTCGACTA[T/A]GAGCAAATCAAAATCAAGAGGATTGAAGACTCGACCAATCCGCTGCTGAT
Long Flanking Sequence:
AGCCTCATTGCCAGTTCACTGAAGTGATATAGTTGATATTGTTATACAAGCTGCAACCATTTTAATTATGATTCAGAGTAAGAAAAAGCTGGTCCAAAAACTGACATATTCTTCATGTCTATGTCTGGTAAAGCCCTATGTAATATTAAATAAATAATCATTGGAGCTGATCCTTCCTTTAAATAGCATTTGGACAGCAAATTTCACAATGACATGCAATCCCATCTCCTGCGATGTGGTATTTGAGGAAGAGGGGTACGTGTTTTCCTGGGTCTATGCATGCAACAAGCACCAGGGCAATGTTTTGTCCAGATCAATAACAAAATATTTAAACAACTCGAAGTCGACATTTTTTTTGGTTTTGTTTTCATTCACTTAGCTGTGTTACACACTGTATGGAAGGTCATTTTCCAAAACCCATCATAGGGACTCTTTATTGTTTATGTCTGTGTTTTACAGGAGGAAATGACTAGTGCCTTGGCAACAATGAGAGTCGACTA[T/A]GAGCAAATCAAAATCAAGAGGATTGAAGACTCGACCAATCCGCTGCTGATAAAGAGGAGAAAGAAAACCACCGTAGCTCCTGAAAACGAGACTCCTGCTTGTTAAGGACACATTCGCACACGCACACACACAATTTGTGTTGAAAAGTTCAGTTTAAGGAAGCAATAACTCGGTGGAGTTTAAATTAGTTTATTTTTTAATATTTCCTTTTAATCACTCAGTCTCTGTAATTAATACATCACTTTGCTACCAAAAGAAAGGGGCTGTACAGTTCTCATACAAGTCTGTACATTTTGTGAAGCAGCCAACATCCACTAATTTGCTCCTTAAAAATGTTCACGTACTGTTTTTCACATGGTGTTCAATGGGTAATCAGAAGTTGTTATCCGTCTTTTCTATTTTATTTTATTTTTCTGTCCTTTTGTTTTAATCATAAGCCATTGGTACATGAGTTCATAAGTGTCACACACACCACTGTTTGTTTTAATGTCCCATTTTCA
Associated Phenotype:
Not determined