ZMP

eif2ak4

Ensembl ID:

ENSDARG00000077010

ZFIN ID:

ZDB-GENE-090302-1

Description:

GCN2 protein [Source:UniProtKB/TrEMBL;Acc:B5U809]

Human Orthologue:

EIF2AK4

Human Description:

eukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:19687]

Mouse Orthologue:

Eif2ak4

Mouse Description:

eukaryotic translation initiation factor 2 alpha kinase 4 Gene [Source:MGI Symbol;Acc:MGI:1353427]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa24807	Nonsense	Available for shipment	Available now
sa38198	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa24807

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000112556	Nonsense	196	553	4	13

Genomic Location (Zv9):

Chromosome Zv9_NA561 (position 71287)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	KN150326.1	71287
GRCz11	KN150326.1	71287

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GAAGTGACTCTGCTGTCGCGGCTCAACCATGAGAACATCGTGCGCTATTA[T/A]AACGCCTGGATCGAGCGGCAGGAGATGTCTTCTGGAGCAGAGCTGACCAG

Long Flanking Sequence:

TTCTGTGTGTTTGTAAATGCGTGTTTTGATAATACCTGCGATCCAGTGCGTCTCTTTATCGAGAGTAAACGTGGCACAGACCATGTAACAGTAGCTACAAATTAAAATTAAAGCTGCAGTAGGTGATCGTCTTTAAAAACGTGTGCTGTTGTGCTGGTTGAAAGTCTCTTCACATTCCAATAGTACTGATTAAAGTAAATGATCTAAATGTGTTTATGTGTGTTTTTATATCCTGGATCAGGCATAAGACTAAAAAATGTTCGTCCAATTAAATATTGTTGGACCGACAAACATTTCCATTACGACAGTCATCTCAAATTAAAAATTGAGTTTCTGCGGATGCTCACTTTTGTCTCCTTACAGGTGCAGAATAAACTAGACGGCTGTTATTACGCGGTGAAGCGGATCCAGGTGAACCCGGCCAGCAAACAGTTTCGCAGAATTAAAGGTGAAGTGACTCTGCTGTCGCGGCTCAACCATGAGAACATCGTGCGCTATTA[T/A]AACGCCTGGATCGAGCGGCAGGAGATGTCTTCTGGAGCAGAGCTGACCAGCGACAGTTCTGAGGCCCTGAGCACACCTGAGCGTCCTTCCCGACCTGCCGCTCCCTCCCGCAGAAATGAAGATCTGAGTCTGCTGGGACGCCTAGAGGAGGAGGCTCCGCCGCCGGCTCTGGCCAGCTCTGTGGAGTGGAGCACGTCTCTGGAGAGATCCAGCAGTGCTAAATGCAGCACCGCAGACTCTGAAGATGAAGAGGAGGAGGAGGAGGAGGATGTCTTCTGTCCATCATTCCTGTGAGATTTGGACAACACTTACACTTAATACACAAATACACTTTATTAAACATGTATACAGATACAATGACATCACATACAGTTGAAGTCATAATTATTCGGCCTCCTGTGAATATATATATACATAGCACTGTCAAAATTAACGCGTTAACGCATGCGATGAATTTTAAATAATTAATGCGTTAAAACAAATTAACGCAGTTCAGGTTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38198

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000112556	Essential Splice Site	498	553	11	13

Genomic Location (Zv9):

Chromosome Zv9_NA561 (position 51807)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	KN150326.1	51807
GRCz11	KN150326.1	51807

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCATGAGCACCGCATCAGAGCGCATATTTGTGCTTAGTCAACTCAGGAAA[G/A]TGAGTTTCATCAAACACATCCCACTGTCATCAGTTTATTCTTCATCATCT

Long Flanking Sequence:

GTGAATTAGATTTATGCACAAATCTGTAATATGGCATTAATCATTAGTCAATAATCAGCGTGTCCAGTCAGTGAGAAACACAAGAGCATTACCTCCCCAGCTCCTGCTGCTCCTGCACAGATATCACTGAGAGGAGTGTAGTTTGCTGCACTGTTGGGATTCTCCACTGTAGTGTTTGTTCTCCTCTAATAAATGAGCCTCAGAAAACCAAGACCAAACGCAATGAATGCAGTGAATGCGGTGGCTTCTGGAGGCTTGAAACGGGAGCGAAGACAGATGCTCAGGACCGTTCTGGAGGGAATAATAATAGAAGAAGAAGAATACTGACGCACCGTGATGACGGACTGACATAGCTACTGTCTGGCTCTCTCTCTCTCTTTCTCTCTGTGTGTGTGCAGAAAGTGGATCTGTTCAGTCTGGGCATCATCTTGTTCGAGATGTCCTACAGGCCCATGAGCACCGCATCAGAGCGCATATTTGTGCTTAGTCAACTCAGGAAA[G/A]TGAGTTTCATCAAACACATCCCACTGTCATCAGTTTATTCTTCATCATCTGTCGCTCAGAACAAACACACACATGATGAACATTAGGGATGTATTGAAAGTAAAATCCTCGTTCTGTTTGTCCTGCAGGAGTCCATTACTTTCCCTGAAGATTTCTGCAAGTATGAGAGTGGAACGCAGGTGACACACGTTTTTTTTTTAATGTTTTTCTTTTTGTTAGTTTATCTACAATAACTTTTCAGCCTTATAGTAGTGTATTTATTTGGCACATTATGTGTATAACCACAGTTTTAGTGGTTATTTGAGGAGCAAACAGGGCAAACAGAGCCCAACAGAAACAGAAACGTACACTGTGCCAGAATTACACTGCAAAAAAATGTTTTTTTTGTTTTGTATCTTGTCCGAATATCTAAAGATTCTTAAATCAAGAAGCATTTTCCAGACAAGCAAAGCTAATGTGCTTGTATTCAGAAATAATTTGCCAAAATTAAGCGAGTTTTT

Associated Phenotype:

Not determined