ZMP

tph1a

Ensembl ID:

ENSDARG00000029432

ZFIN IDs:

ZDB-GENE-030317-1, ZDB-GENE-030317-1

Description:

tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a [Source:RefSeq peptide;Acc:NP_840091]

Human Orthologue:

TPH1

Human Description:

tryptophan hydroxylase 1 [Source:HGNC Symbol;Acc:12008]

Mouse Orthologue:

Tph1

Mouse Description:

tryptophan hydroxylase 1 Gene [Source:MGI Symbol;Acc:MGI:98796]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa38011	Nonsense	Mutation detected in F1 DNA	Not yet available
sa24612	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa38011

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000041676	Nonsense	91	473	3	14
ENSDART00000067159	Nonsense	91	483	3	11

Genomic Location (Zv9):

Chromosome 25 (position 8415460)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	25	8027925
GRCz11	25	8152017

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACCATTGTTTATAGGAAAACCATGTAAACCTTGTACACATTGAGTCCCGG[A/T]AATCTAAAAGGCGCAACTCAGAGTTTGAAATCTTTGTGGACTGCGACAGC

Long Flanking Sequence:

CTGTTTTTGTATACTGTTACTTTAAATGCAAATGAGCTGGTTCTCCCCGCCCACCGTTTTTGGCAAGAGAACTATGAGTGAATGATGACAGAATTTTCATTTCAGGGTGAACTGTCTTAAAGTGTAATTCTACACTTAAAATATGACTGTCAGATTGATTTGATATTTATTAAGTTTCCCGTTTGTATTTTACAGATGAACAAATCTGCTTTCACGAAGATCGAGGAGAATAAAGACAACAAAACAGAGTCTTCAGAGACAGGCCGGGCTGCGGTTGTGTTTTCCCTGAAAAATGAAGTCGGTGGGCTAGTCAAGGCTTTAAAGCTTTTCCAGGTAACGTGAGGTTTTATTTAAGTTTTCTTGAATATTTATATACATTTATTACATTTAAAAAAAAAAATAAATAAATAAATAAATAAATAAATAAATAAAGTTAATTCTTTAAATTTAACCATTGTTTATAGGAAAACCATGTAAACCTTGTACACATTGAGTCCCGG[A/T]AATCTAAAAGGCGCAACTCAGAGTTTGAAATCTTTGTGGACTGCGACAGCAACCGTGAACAACTGCACGAGATCATTCAGCTGCTGAGGAAACATGTTAACGTGGTGGAGATGGACGCGCCTGACAACCGCCTGCCTGAGGAAAGCGGTATGAATGTCTTTTAACATGAATGAAATAAATTCATAAATAAAAAAAAAGTGCTAAACGCATCATTTTTTGTATGACATTTTATTTTAAGGTGCAATTATCTCTATCAATAAAGCATTAATTATTTAAATATACCCCTAATTTGCTGCTGATTATTAGTTAGTAAGCTAGTTGGGTTTAGGTAGGATTAGTGATGTAGAAAGAGATCACGCAGAATTTATGCTTCTTAAGTACTATTAAACAGTCAATATCTGTCAGGATATATGGAGACCCAAGCGCAAGGGAGAAGATTAAAGGAATATTTATTAAACAAAACCAAATCCACAATTCTGCTCTCCTTGGCAGTAAGTAAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24612

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000041676	Nonsense	303	473	7	14
ENSDART00000067159	Nonsense	303	483	7	11

Genomic Location (Zv9):

Chromosome 25 (position 8410196)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	25	8022618
GRCz11	25	8146710

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CGTGTGTTTCACTGCACTCAGTATGTCAGGCACAGTTCAGACCCGCTCTA[C/A]ACACCTGAGCCGTGAGTATATGATCATGATTATTAAACATAATCAAACTC

Long Flanking Sequence:

TAGTAAACCATTAGAATATTCCAAACTCACTATAAATAGCCCGTCTAGTCTTACTCCCTTATCTAGTATTGTGAAGAATCTCCCCATCTCCCTCTTTCTTCCTTTACCAAGGGGAACTTTCAAGAACTACCTGATCTCGTATCCCCTTACAACTATCAATTATCTCCGAGCTCAGGGTTCTCTCCTGGGACAGCATGCCAAATCTGCTATTATTAATCAAGCAATATCTAAGTGTGGACTCTTGAACATTGTTGAACATGATTAGCTTTGGTTCATTCAATATGTAAGTTTACCAAACTGGAAATGCAACCCATAATGTGAAATGCAATAGTATTAGTAGACAAATATGAATAATGTGGTTTATTGTCTGTTTCAGAGAGAACAGGCTTCACCATCAGGCCTGTGGCAGGATATTTGTCTCCTCGAGACTTTCTGGCAGGATTGGCTTTCCGTGTGTTTCACTGCACTCAGTATGTCAGGCACAGTTCAGACCCGCTCTA[C/A]ACACCTGAGCCGTGAGTATATGATCATGATTATTAAACATAATCAAACTCATGATTAAACCTCTGTGTCTAAACTGATTGCAAAATGTGTTTATACATGTCATTTGTATATGTTGTAATTACATTTATTTATATTTCATAAAATGCATGTGCTTGTTTAAAAATAAAATAATTAAGTGATAAAAACAAGCAAAATTAACAATATTGATTAATATCTAATATATGAATATAATATAATATAATATAATATAATATAATATAATATAATATAATATAATACATTTCTGAGCATTTAATATGTTTATGTGTATACATATATTCATTTGTTTGTTATTTATTTATCTTTTGTTTTTGTTTTTTTCTTGAACTTTACAAAATTATTAATATCAAATAAATTCAAATGTATATGTGTATTTTTCATATATTTCTCTATATAAACTTTATTTTTATATTTTATTTAATATGGTATACAATAAATGTTTATATATAATGCATTTATTT

Associated Phenotype:

Not determined