Busch Lab

ZMP

cul1b

Ensembl ID:
ENSDARG00000007691
ZFIN ID:
ZDB-GENE-040426-2887
Description:
cullin 1-like [Source:RefSeq peptide;Acc:NP_998660]
Human Orthologue:
CUL1
Human Description:
cullin 1 [Source:HGNC Symbol;Acc:2551]
Mouse Orthologue:
Cul1
Mouse Description:
cullin 1 Gene [Source:MGI Symbol;Acc:MGI:1349658]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa1559 Essential Splice Site Available for shipment Available now
sa37858 Nonsense Mutation detected in F1 DNA Not yet available
sa24472 Nonsense Available for shipment Available now
sa45827 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa1559
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024691 Essential Splice Site None 774 1 22
ENSDART00000122757 Essential Splice Site None 320 1 10
ENSDART00000134947 Essential Splice Site None 775 1 22

The following transcripts of ENSDARG00000007691 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 24 (position 17949169)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 17255645
GRCz11 24 17400064
KASP Assay ID:
554-1502.1 (used for ordering genotyping assays)
KASP Sequence:
GAGCGCAGGGCCTCGACCTCACACTGCTCGACGTTACAAACACACACAGG[T/A]AAGACTAAAAATCTTTAAACACGTGTCAGGCGTCCCGGTTTGACATAAAT
Long Flanking Sequence:
TTTTTGGAAGGTTTACTCATACTTTGAGTAATATTTACAACAGATACTTTTACTCTACTTCCACTACATTTTAAGCAAGTAATGGTACTTTTACTTGAGTATGATTTTTCAGTTCTCTTTCCACCACTCACTGACTGAGTAATATTTACAACAGATACTTTTACTCTACTTTCAACTACATTTTTAGGCAAGTAATGGTACTTTCACATGAGTATGATTTTTCAGTACTCTTTCCACCACTGGTGGGTTTTACACACATTTTTTGAGTCATTCGCAGCAGGAATGGTCAAAGTGGTTCCTGGCACCTGAAAGAGTGAAGCTCCTACGCAGCTGGTGTACTACGGTGAGTGGACAGTAGGCGTCGCTGTGTGTCTCTGCGCTGTGGCGTATGACGTTTCACTCGCTCTAATACGGAATTCCCAGTCATCTCCAGTCAAACACACACAGACTGAGCGCAGGGCCTCGACCTCACACTGCTCGACGTTACAAACACACACAGG[T/A]AAGACTAAAAATCTTTAAACACGTGTCAGGCGTCCCGGTTTGACATAAATGAAAACTAAATGGACGTGTCTGGCAATGTGTCGATAAGGAAGAGAGACATTTTTGTGATATTACACACCAGTTAAGAATAGGTAGCCATTTTACATCATTATATCTCAAAAGCCTCGGAGAATAACAGTAGTGGGTTAATAACAAATGTTTGTCTTGATTTTCAGGTTATATTTAAATGACGTACGTTTGGTTGACATTATGGTATTAATAGTTCCTCTTAGCGGCAGTTTACAAGGAAGGGTACCTGAAGCTAACGAGCTTGCTACCTAGCATTGCTAATCTATTGATGCTGTTTACAAAACAATATCGCCATATAAATGTTCATGAATTAAATACTTAGTGCGTTTAATGTGTTAAGAAGTATATTATGGAGACCTAAAGCTGTAAACAAATGCTGAGGCAAAACGAAGAGTCCTTTACACACATTCACATGAATTCTGCTGTCTCAG
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
sa37858
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024691 Nonsense 50 774 3 22
ENSDART00000122757 Nonsense 50 320 3 10
ENSDART00000134947 Nonsense 50 775 3 22

The following transcripts of ENSDARG00000007691 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 24 (position 17933679)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 17240155
GRCz11 24 17384574
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTATTCTCTTACTGCCTTTTGACTTTAACCTGCTGTTCAGACATGTGTA[T/A]AACTACTGTACCAGTGTACACCAGGCCAGGCCTACTGGCATCCCCTCGTC
Long Flanking Sequence:
ACTAAATAGTTATAAGAGACATGTTTAAGGCATATATTCAACATCCTTAATTAAGGAAAGATCTCCACTTTACCATTCTTAAAGGGAAAATGTGCTTTATGCAATAGCAAAGTTATATAAATCTTGAAGCATCAAAATCCGTACTCTGTATCGGCCGATCCTCATGATAAAGGAATTGGAACTCTATATCGGCTGCAAAAATCCTGACCAGAGCATGTCTAATAGTTACCGTTTTTCTAGACCGCATAGATAAAATCTTTTTTGACTTGACGGTTTAAGTGTGTCCAGCAGCTTTTTCATGCAAGATAAGAATTGTTAGAAATCATATCTCCATGATTGTTGCTGTATTACAGTAGTATAACTGTTTTTGACTGGTTTAGGTCTGTCTTGCATAAAGAAACAGGACCAAGAAACTGCCAGGAGGTTGCTAATGTTATCAATCTGTCATAATTTATTCTCTTACTGCCTTTTGACTTTAACCTGCTGTTCAGACATGTGTA[T/A]AACTACTGTACCAGTGTACACCAGGCCAGGCCTACTGGCATCCCCTCGTCCAAACCCTCCAAGAAAACACCCACACCTGGGGGGGCACAGTTTGTTGGACTAGAACTCTACAAAAGACTCAAAGATTTTCTGAGGAGCTACTTGACAAACCTTCTCAAGGTAACAGCCTACAGCTTGCATGCATAATATTGTTCAGGATATATTGTTGTTGGTATACATGAAACTACTTTGAATGCTGGCTCGAAATTCATTCATAAGATACGTTTATTCTATTACCCTTTTCTTGAATTCAAAAAAATCTGTATACATTTGTTGTTTCCATAATCACTTGTAATTTGTTGTTTTTCTACTAATGCCATGTTGTATCTGACCATGCACGTCTCAGTAATGAGTAAAGATGAAGTCTTGGAATCGTCGTTTACAGACTGAGGAGTTTAATGAGACATGGAGAAAATGGGGAGAATATATTCTTCCATTAAGACCAGACTTAATATAGAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24472
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024691 Nonsense 411 774 11 22
ENSDART00000122757 None None 320 None 10
ENSDART00000134947 Nonsense 412 775 11 22

The following transcripts of ENSDARG00000007691 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 24 (position 17920972)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 17227448
GRCz11 24 17371867
KASP Assay ID:
2261-8595.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAGGCCTGTGGAAGATTCATTAATAATAATGCAGTAACAAGAATGGCA[C/T]AGTCCTCCAGCAAATCCCCTGAGCTTCTGGCCAGATACTGTGACTCCTTA
Long Flanking Sequence:
TATTTTTGTGTCATATGTAATTAATCATTTATGTGTTGTGCGTAAAGAATGTGTTTCAATCCGGCTACCACCGCGAGTGCATTTCAAACCAGTGTAAAGCACTGGCCAGTAATATTTATCTCCATTAATCCTGGATATCATGTTAGTTTGTTTTTGTTTTTTTTGTCGTGCGTGTTTCCCGGTACATCTGCTCTGCTCAGTTCCTGTAAGGCCTTAATTTGATCACAGTCTGAATTGTCACTTCTTGTTTTTCAGGATCCTAAAATGTATGTGCAAACTACCTTGGATGTTCACAAGAAATACAATGCTCTTGTCATGTCTGCGTTCAATAATGATGCCGGGTTCGTGGCGGCACTGGATAAGGTTGTAAGCTTATATGAGATCTGTTGTGTACTATAGTGGTTATTATTAGCCTCTGGTGTAATTTTCATTCTGTGATCTGTGCTGGTCTTCAGGCCTGTGGAAGATTCATTAATAATAATGCAGTAACAAGAATGGCA[C/T]AGTCCTCCAGCAAATCCCCTGAGCTTCTGGCCAGATACTGTGACTCCTTACTGAAGAAGAGGTGATTCTCTCATTCACATCATTATTGGTGGACCAGACCCCATATCAGGCTTTCATTTTCATCTTTTAAGAGTAGAGTTTTGAATCTTTTTAGTGCAATAAAAATGAGCTGACAATAATATCTAAAGAATGAAAACTGCATTAGCAAGGCTCTATATTTGAAACTGAGGATTTAACCAAGTTTGTGTTGTGTTTAGTTCAAAGAACCCAGAGGAGGCTGAACTTGAAGATACTCTCAACCAAGTGGTGAGTTTTTGTTTTCCACTGATATTACTGCTCATAACAGCGTCTTTTCTTCATTGTAATGAAATTAATTTCATTTACTTTACAAATTTACAAAGCCTAAATATTTATTTCTAGCAGAACTTAATCTAGATTACTATTTAAAGATTGTTTTCAGCTTAATTGAATTCACTTTGCCTGAACTTTTATTTTAAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45827
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024691 None None 774 22 22
ENSDART00000122757 Essential Splice Site 320 320 10 10
ENSDART00000134947 None None 775 22 22

The following transcripts of ENSDARG00000007691 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 24 (position 17914003)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 17220479
GRCz11 24 17364898
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTGTCTTTATGCCCTTAAGCTGCTCAGGATTGCCATTTACTTTTTAAA[G/T]ATGTAAATAACTGGACATTGAACTAAACTCATAGTGGGACCCAGCGTCAG
Long Flanking Sequence:
TCAGAATATTTTCGAGTGTCCTGGGCTGATTTTTGCTGTTTAATCTGATGAAAATTGAACTTTTTAAATGTTTTGAAATTTTTCCACATTTTTCGAGTGCATGGGACTGACTTTTACTGTTTATTCTGATAATGCCAAAGAGCAGCAACGCATTATTTAAGCTTATTTGCATTATTTGAGCACATTTTGTTTAATTTAGGACTTTTATTATTTCAGAAATGCATTGACATTTTGATAGAGAAGGAATACCTGGAACGTGTAGATGGGGAAAAAGACACGTACAGTTACCTGGCATAAAAACAACATCCTCTGGAGTTTGCCGTCCTTCCTGAGATGCATCTTTTTGAGGAGCGTCAAGAGTGGACGCACACAAACCGAGGACTCTCAAGACATTGCTGAGTAAGACACTGGACCTTTTCCCTTTAAACCCAGACTGCTAAAGCGGCCAGTCTTTGTCTTTATGCCCTTAAGCTGCTCAGGATTGCCATTTACTTTTTAAA[G/T]ATGTAAATAACTGGACATTGAACTAAACTCATAGTGGGACCCAGCGTCAGGGTTGCATGCTATAATGCCTCTCAATATAAAAGGACAAAAACTGATTAATTGTGATTCCGTCTTTTGGGAAACTGACATATTGAAAAAAAAAAAAAAAAAAAAAAGATGAAGACAAGAAATACTGTTAACTAAGAGCAAAGCCAGTAAAATCATGTCAGATCGGCTGTTTAGAGATGCATCGTTTCCAGCCAGGAGAACAGCATTTGTATAGTGCAGCTCATTTTATAAATGTCATGAATAAACTTAATTTTTCTTTATACTTTAGTCTTGCTCATTTATATCAAGGAGAATGCAGCTTTTTAATGTATTCACTGTCTGAAATATAGGTGATTTTTATTTCTTCAGCTGATATGAGAATCATGAAACAAATGAATATCTGGAAGAGTACAGCAGACAGTTATTTTCAATGTTTATTTTCTCACGTTTAACAAGTCCTTGTAAACAATTGA
Associated Phenotype:
Not determined