Busch Lab

ZMP

chrna7

Ensembl ID:
ENSDARG00000035785
ZFIN ID:
ZDB-GENE-040108-3
Description:
neuronal acetylcholine receptor subunit alpha-7 [Source:RefSeq peptide;Acc:NP_957513]
Human Orthologues:
CHRFAM7A, CHRNA7
Human Descriptions:
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence simila
cholinergic receptor, nicotinic, alpha 7 [Source:HGNC Symbol;Acc:1960]
Mouse Orthologue:
Chrna7
Mouse Description:
cholinergic receptor, nicotinic, alpha polypeptide 7 Gene [Source:MGI Symbol;Acc:MGI:99779]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa21086 Essential Splice Site Available for shipment Available now
sa21087 Nonsense Available for shipment Available now
sa2371 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa21086
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051931 Essential Splice Site 199 509 6 10
ENSDART00000134733 Essential Splice Site 200 510 5 9
Genomic Location (Zv9):
Chromosome 7 (position 55674791)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 53379719
GRCz11 7 53649371
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGATGCCGACATCACAGGATACATTGCTAATGGAGAGTGGGACCTTGTGG[G/A]TAGGGTGACCGACTTCATTAAATACCAATGCTTGAACAGAAGATAATGAA
Long Flanking Sequence:
TTCAAATATATTATGCTAACCAGTTAGCATTTAGGCAGATCACTTCCTGCACCTTTAAGCCTTTAAAAAGTACTTTACCCTGAATACTAGTATCTTGAAAAATATCTAATAAATTATAATAAAATAAATCAGTTATTAGAAATGAGTTATTAAAACAACTATGTTTGGAAATATGTCGAAAAAAATCTTTCCATTAAACAGAAATTGGGAAATAAAATAAACAGGGAGGCTAATATTTCTGGCTTCAACTGTATATGTGCAGCTGGAGGACTTGTTTTACAACCCTCCACTGAAACTGTTGCACTGCAGTTATAACACATTTCTGTTTATAGGGATCTTCAAAAGCACCTGCTACATTGACGTTCGCTGGTTCCCCTTTGATCTTCAGAGGTGTGATCTGAAATTTGGCTCCTGGACGTATGGAGGATGGTCTCTGGACCTGCAGATGATTGATGCCGACATCACAGGATACATTGCTAATGGAGAGTGGGACCTTGTGG[G/A]TAGGGTGACCGACTTCATTAAATACCAATGCTTGAACAGAAGATAATGAAAGACCACTTAAAGAGAGTGCACGTTCATGACTTTCAATATAAGTCAGACTGTTCGATGTGAATTGATTTCGTTTCAATTATATTTTGAAAAATGTTTTTAAGTACACTTGATGTTGTTGACAGATTTCTTAAAAGTGCATATAAAGTACTAAAAATTTTAAGTGTAACTAGTCTTTCTATAGTTCACTTTTTAAAAATAGGAAAACTGCAGCTTCATCACTGAAAATGTGCAATGAAATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATTGCAGAAGTTCCAGGTAGACGGAATGAGAGGTTCTACGACTGCTGCAAGGAGCCGTACCCAGATGTGACTTTTACGGTGGTGATGCGGAGACGAACACTGTATTACGGTCTTAATCTACTTATTCCCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21087
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051931 Nonsense 233 509 7 10
ENSDART00000134733 Nonsense 234 510 6 9
Genomic Location (Zv9):
Chromosome 7 (position 55675268)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 53379242
GRCz11 7 53648894
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACCCAGATGTGACTTTTACGGTGGTGATGCGGAGACGAACACTGTATTA[C/A]GGTCTTAATCTACTTATTCCCTGTGTGCTCATCTCTACTCTGGCCCTGCT
Long Flanking Sequence:
TAATGGAGAGTGGGACCTTGTGGGTAGGGTGACCGACTTCATTAAATACCAATGCTTGAACAGAAGATAATGAAAGACCACTTAAAGAGAGTGCACGTTCATGACTTTCAATATAAGTCAGACTGTTCGATGTGAATTGATTTCGTTTCAATTATATTTTGAAAAATGTTTTTAAGTACACTTGATGTTGTTGACAGATTTCTTAAAAGTGCATATAAAGTACTAAAAATTTTAAGTGTAACTAGTCTTTCTATAGTTCACTTTTTAAAAATAGGAAAACTGCAGCTTCATCACTGAAAATGTGCAATGAAATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATTGCAGAAGTTCCAGGTAGACGGAATGAGAGGTTCTACGACTGCTGCAAGGAGCCGTACCCAGATGTGACTTTTACGGTGGTGATGCGGAGACGAACACTGTATTA[C/A]GGTCTTAATCTACTTATTCCCTGTGTGCTCATCTCTACTCTGGCCCTGCTGGTGTTCCTGCTACCTGCTGACTCAGGAGAAAAGATCTCGCTCGGTGAGCTACACATTGAAGGCTTTTGCCATAATTTTAAGATGTTAATATATATTAGGGGTGTAACAGTTCACAAAAATCACGGTTCGGTTCGATACGATACAGTGGTGTCACGGTTTGGTACGTTTTTGATACAGCAAAAAAAGAAAAAAGCCGGAGGATTTCTCTGGTTTTTATTTTTTAATGTATTAAAAATACCATCATAAAAGTATGATCCTGTTTTTGATCCTGATCCTGAGCTATGCTTCTGGGGTTTCTGCTTAGCAGCAAATAAAACAAATCCTTCTTTATACTCAAAACCAAAAAGCTTCCTAAAAAAATAAATGTAATATTGTAGTAGTTAAACAAATAAAAATAAAAGAACAATCTATAGTCTATTTTCAAGTATTTTTTTTTTCAGAAAGATGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2371
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051931 Nonsense 448 509 10 10
ENSDART00000134733 Nonsense 449 510 9 9
Genomic Location (Zv9):
Chromosome 7 (position 55682640)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 53371870
GRCz11 7 53641522
KASP Assay ID:
554-3029.1 (used for ordering genotyping assays)
KASP Sequence:
AGCGGCCCTGGAGAAACCGAACTKTCCAAGATCTTGGATGAGGTGCGGTA[C/A]ATTTCCAAGCGCTTTCGGGACCAAGACGAGGAAGACACTGTGTGTAATGA
Long Flanking Sequence:
TGAAGGAGGAAAAATGCCAAAATGGGTGAGATCCTCATTTCTGCATTGATTTTTATTACTTTATAAACCAATCAGGTTGAATTCATCAGTATTTCATATTTTTTAATGTCAGCGCTTTGCCATTTAACAGCTATTTTTGTGTGTTAGACACGTGTGGTGCTGTTGAACTGGTGTGCCTGGTTCCTGCGGATGAAGAGACCTGGCGAAGACAAAGTTCGCCCAGCTTGTCACAACAAGCAGCCGCGCAGCAGCCTCTCCAGCGTGGATCTAAACATCAGCCCTGGAGTCGCACAGTCCACCAATGGAAACCTGCTGTACATCGGCTTCCGCGGGATGGACACTATTCACTATGCTACTTCACCTGATTCTGGGGTGATCTGCAGCCGGCTTGTGGCGACCGGAGAGGAGGATGTGCTGCTCCCCGGAGCCCAGGCATCTTCAGTTAGTAGTAGCGGCCCTGGAGAAACCGAACTGTCCAAGATCTTGGATGAGGTGCGGTA[C/A]ATTTCCAAGCGCTTTCGGGACCAAGACGAGGAAGACACTGTGTGTAATGAGTGGAAGTTTGCAGCGTCTGTGATTGACCGTCTCTGTCTCATGGCTTTTTCCCTGTTCACCATCCTCTGCACCATTGGTATCTTAATGTCTGCCCCTAACTTTGTTGAGGCCATATCAAAAGATTTTTTCACCTGAAGCCTTCACTTACCCTTATATTGTAGCTATATCTACTTCTCAGAGTCTCCTAAAGGCACAGTATGTATGGCTTTTGCACTGAAATATCCAAAAAACCCTTTATTTTGTTGACTTACTTGTATTGTACCAAAAGGAAGAAAGGATGTATATAAGAGCCCAGCCAGATCATCCTGTAGCCCAAAACTGATAAAGGTAAGCAGAGCCAAAGTCATATTACCCTGTAGCTAAGCAGGATTGAGCCTGGTCAGTACTTACAAGGAAGACCACCAGGGAGAAACCTGCTAGATCTATTGCTAATGAGGCCAGCAGGTGGC
Associated Phenotype:
Not determined