ZMP
top2b
Ensembl ID:
ZFIN ID:
Description:
DNA topoisomerase 2-beta [Source:RefSeq peptide;Acc:NP_001038656]
Human Orthologue:
TOP2B
Human Description:
topoisomerase (DNA) II beta 180kDa [Source:HGNC Symbol;Acc:11990]
Mouse Orthologue:
Top2b
Mouse Description:
topoisomerase (DNA) II beta Gene [Source:MGI Symbol;Acc:MGI:98791]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa11711 | Nonsense | Available for shipment | Available now |
| sa23498 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa11711
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000029024 | Nonsense | 343 | 1613 | 9 | 35 |
| ENSDART00000130695 | Nonsense | 348 | 1618 | 9 | 35 |
Genomic Location (Zv9):
Chromosome 19 (position 19721914)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 18275049 |
| GRCz11 | 19 | 17733614 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGGWACTCATGAGCTTTGTGATATTTTAGGGAGGAAGACATAKCGATTA[T/A]ATAGTGGACCAAATAGTGGGGAAATTGATTGAAGTTGTGAAGAAGAAGAA
Long Flanking Sequence:
TGTTTTGTTTGTATGCAACAGTTATAAAAGAAGATGATTATGCTTATGATTATTACTTATGCTGATTCTAAAATAAAACACATTCCTAATGCTAGAGAACAGCAATGCAATATTTTGCAACTGGGTTTAAAGAGGGTGATTTTAAAGATTTATCTTTTAAAGTGTGTTTAATTTTGCTCCTGGAAGGCCAACATACTGCATATTTTAGCTCCAACCAGCTTCTAAACATTTGAAACCAATTTTGCAATTGTACAAACACTGGAATTAGCTAGTTAAAGTCTCTAAGGTTTGTGTAATTGTAGTAAACTCAAGATTGTGTCCCTCCAGGAGCAGATTTGGACACTCCTGTACTAAACTGACAGCAAAAACACATCATTATCTGCAATACTCATTATGCTCAGTACTTATAAAGGTGTTTTTGGTCATGTCTCTCCAGCTTTTTTAAATGATGTGGTACTCATGAGCTTTGTGATATTTTAGGGAGGAAGACATATCGATTA[T/A]ATAGTGGACCAAATAGTGGGGAAATTGATTGAAGTTGTGAAGAAGAAGAACAAAGCCGGAGTATCTGTAAAACCATTCCAGGTAAATTTTTGCTACTCATTACCCCCTTATAATAATACTATCATATTCAGTATTACACATATATTCAGGGTCTTTGGTTTTTCATTCTCTGAAATTTTGGTGGCTCTGAGATGTTTAATTACTATGTTTTAATTATTTGTTTTGTTTATTTCAGGTTAAAAACCATCTATGGGTATTTGTAAATGCCCTTATCGAGAACCCAACCTTTGATTCTCAGACCAAGGAGAACATGACTCTACAGACCAAAAGCTTCGGTTCCAAATGTGCTCTCTCGGAGAAATTCATCAGAGCTGTGCGTGATAATCTCTTAACTTGATTCTCATGTTGTGATTAATCTTTTATTATACATAAGAGGTTGCATTTTCTGTGCACTTTACATTGCACTACAGCATTTAGATTTTTTAATGTGTTATTACAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa23498
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000029024 | Nonsense | 401 | 1613 | 10 | 35 |
| ENSDART00000130695 | Nonsense | 406 | 1618 | 10 | 35 |
Genomic Location (Zv9):
Chromosome 19 (position 19721588)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 18274723 |
| GRCz11 | 19 | 17733288 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAACCCAACCTTTGATTCTCAGACCAAGGAGAACATGACTCTACAGACC[A/T]AAAGCTTCGGTTCCAAATGTGCTCTCTCGGAGAAATTCATCAGAGCTGTG
Long Flanking Sequence:
GGAGCAGATTTGGACACTCCTGTACTAAACTGACAGCAAAAACACATCATTATCTGCAATACTCATTATGCTCAGTACTTATAAAGGTGTTTTTGGTCATGTCTCTCCAGCTTTTTTAAATGATGTGGTACTCATGAGCTTTGTGATATTTTAGGGAGGAAGACATATCGATTATATAGTGGACCAAATAGTGGGGAAATTGATTGAAGTTGTGAAGAAGAAGAACAAAGCCGGAGTATCTGTAAAACCATTCCAGGTAAATTTTTGCTACTCATTACCCCCTTATAATAATACTATCATATTCAGTATTACACATATATTCAGGGTCTTTGGTTTTTCATTCTCTGAAATTTTGGTGGCTCTGAGATGTTTAATTACTATGTTTTAATTATTTGTTTTGTTTATTTCAGGTTAAAAACCATCTATGGGTATTTGTAAATGCCCTTATCGAGAACCCAACCTTTGATTCTCAGACCAAGGAGAACATGACTCTACAGACC[A/T]AAAGCTTCGGTTCCAAATGTGCTCTCTCGGAGAAATTCATCAGAGCTGTGCGTGATAATCTCTTAACTTGATTCTCATGTTGTGATTAATCTTTTATTATACATAAGAGGTTGCATTTTCTGTGCACTTTACATTGCACTACAGCATTTAGATTTTTTAATGTGTTATTACAACTGAATGATTTCCCTTCACAGGCCACAAACTGTGGTATCGTGGAAAGCATTCTTAACTGGGTGAAGTTTAAAGCTCAGACACAGCTGAACAAGAAATGCTCCTCTGTCAAACACAGTAAAATTAAAGGTATTCCCAAACTAGATGACGCCAATGATGCAGGTGAGCTTATAGCAGATAAACTTATAGCTATATCTGTCAATTAGATTTGCACAACATGGGTCAAAACATATATTTCTGTTTTTTTGTTTTTTTCATAAAGCAAACTGAATAGATGATTAGGGCTTGCAAGGCTCTTTGTTTTATGGCCAATCACTATTCAATCTTTG
Associated Phenotype:
Not determined