ZMP
chrna5
Ensembl ID:
ZFIN ID:
Description:
neuronal acetylcholine receptor subunit alpha-5 [Source:RefSeq peptide;Acc:NP_001017885]
Human Orthologue:
CHRNA5
Human Description:
cholinergic receptor, nicotinic, alpha 5 [Source:HGNC Symbol;Acc:1959]
Mouse Orthologue:
Chrna5
Mouse Description:
cholinergic receptor, nicotinic, alpha polypeptide 5 Gene [Source:MGI Symbol;Acc:MGI:87889]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45648 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa367 | Nonsense | Available for shipment | Available now |
| sa23361 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa45648
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021372 | Essential Splice Site | 127 | 466 | 5 | 9 |
Genomic Location (Zv9):
Chromosome 18 (position 38790886)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 40503603 |
| GRCz11 | 18 | 40493795 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGGTGCCTTCAGACTCCATCTGGATTCCTGACATTGTGCTCTATGACAA[G/A]TATGTGGTGTTAGAAAGTTTATAAGTCACGCTGCAATTGTTTGTCAGTAA
Long Flanking Sequence:
GATGTTTCAGAATCAACATGTAAATGCACAATTGTGTCCTACTTAGCAAAATCACACCCACCACACAAACTGGGTACTAATCTACCTAGTGTACATTGTAACATAAAAAATAGAGTAAAATAGAGTGCAACCAAATTTATTGTTAGCCATGTTTGTGGGTAACATAGAAATATGGTTAGGGTAAAAAAAAAGGTAAATTACTAGTAATAATTGAGATTTTCTTGAATAGGATGAGAAGAACCAGCTGATGACGACCAATGTGTGGATGAAGCAGGTAAAGCAGTACTTAATAATCCAGTAATATTTTTCTTATGTGGTTCTGGTAGTATTTTGTTAAAGAGTTTCTTAAGTTTTGTTTGTGTGAGACAAATCAATCTCTTTCACATTCAGGAATGGACAGACTTGAAGCTCAGATGGGATCCGGATCATTACCTGGGCATCACCTCTATCAGGGTGCCTTCAGACTCCATCTGGATTCCTGACATTGTGCTCTATGACAA[G/A]TATGTGGTGTTAGAAAGTTTATAAGTCACGCTGCAATTGTTTGTCAGTAAGTGCGCATAATAATATTAAGCAGCAAAATTCAGACAAAATTGTGGGGATATTGAGCAATATACATTTGAAGTCAAAATTACTATTTAATTGTTATTTAAACGAATTATTATTACGTTTTTTTCAAATATTTTTCATATGATGTTTAATAGAGCAAGGAACTTTTCACTGTATTTTCTATAATATTTTTCAAGTCCGGAGAATGTCTTATTTGTTTTATTCTAAATAAAATAAAGGCCGTTTTAACATCTTTTAAAACTATTTTGAGGTCAATATTATTAGCCCAATTAAGCTATTTCTTTTTTTCTATTGTCTAAAGAACAAACAATCGTTCTAGAATGAATTTTAAAATTACCCTGACTTGCCTATATCTTGTATATGTTCAAACACAATTCAGAATTTAGATATGTTAAATAACACTGCAATTATGAATAGATAATTGTTCAGACTGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa367
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021372 | Nonsense | 133 | 466 | 6 | 9 |
Genomic Location (Zv9):
Chromosome 18 (position 38790175)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 40502892 |
| GRCz11 | 18 | 40493084 |
KASP Assay ID:
554-0237.1 (used for ordering genotyping assays)
KASP Sequence:
AGCCTGTCTATATCTCATGGTTGGTTGATTGCAGTGCAGATGGTAATTTC[G/T]AGGCCACAGTGACAAAAGCAGTGGTGAGATTTGATGGCACAATCTCCTGG
Long Flanking Sequence:
TTTTCACTGTATTTTCTATAATATTTTTCAAGTCCGGAGAATGTCTTATTTGTTTTATTCTAAATAAAATAAAGGCCGTTTTAACATCTTTTAAAACTATTTTGAGGTCAATATTATTAGCCCAATTAAGCTATTTCTTTTTTTCTATTGTCTAAAGAACAAACAATCGTTCTAGAATGAATTTTAAAATTACCCTGACTTGCCTATATCTTGTATATGTTCAAACACAATTCAGAATTTAGATATGTTAAATAACACTGCAATTATGAATAGATAATTGTTCAGACTGTCATTTTAATTGGTCAGTTTTTATTTACTAATGATTCCAGCTTCCTGTCAGAAAATCTAAACAAATCATTTGTAAATGTAAACAAAACATTACATTTTGCAATGTTGAAAAGCTACACTGAAAAAGACAGACATGTTAATTTAGCACAGTGTTAATTTTGGAGCCTGTCTATATCTCATGGTTGGTTGATTGCAGTGCAGATGGTAATTTC[G/T]AGGCCACAGTGACAAAAGCAGTGGTGAGATTTGATGGCACAATCTCCTGGACTCCTCCTGCCAACTATAAATCTGCCTGCACCATTGATGTGACCTTCTTCCCCTTTGACCTTCAAAACTGCTCCATGAAGTTCGGTTCTTGGACCTATGATGGCTCCCAGGTATGTTTTTAATTATTATTAGACACCAAAAGCCAAATTCATGTTGTTTCTAAAAAAAAATTAGTTTTTTTTTTTATTTAAGTCGATTAAACATATAACAAATAAATAATATATATATATATATATATATATATATATATATATAGCTGTACGTTTTCAGAATGAGTCTAGGTTGGTTACATTTGATACATTTATCTGATTACTGTTATCTGATACATTTTTACAGCAGTTTAATTTAGTAAACATAATGAAAGGGTAGTAAATTTGCCCAGAGTGACATGTTGAATTTTTTTACAATTGTCTAAATATGGTTTGTCATCGAAAATCTTTCCGCTAGCT
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |
Mutation Details
Allele Name:
sa23361
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000021372 | Essential Splice Site | 186 | 466 | 6 | 9 |
Genomic Location (Zv9):
Chromosome 18 (position 38790012)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 40502729 |
| GRCz11 | 18 | 40492921 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAAAACTGCTCCATGAAGTTCGGTTCTTGGACCTATGATGGCTCCCAGG[T/C]ATGTTTTTAATTATTATTAGACACCAAAAGCCAAATTCATGTTGTTTCTA
Long Flanking Sequence:
CAATCGTTCTAGAATGAATTTTAAAATTACCCTGACTTGCCTATATCTTGTATATGTTCAAACACAATTCAGAATTTAGATATGTTAAATAACACTGCAATTATGAATAGATAATTGTTCAGACTGTCATTTTAATTGGTCAGTTTTTATTTACTAATGATTCCAGCTTCCTGTCAGAAAATCTAAACAAATCATTTGTAAATGTAAACAAAACATTACATTTTGCAATGTTGAAAAGCTACACTGAAAAAGACAGACATGTTAATTTAGCACAGTGTTAATTTTGGAGCCTGTCTATATCTCATGGTTGGTTGATTGCAGTGCAGATGGTAATTTCGAGGCCACAGTGACAAAAGCAGTGGTGAGATTTGATGGCACAATCTCCTGGACTCCTCCTGCCAACTATAAATCTGCCTGCACCATTGATGTGACCTTCTTCCCCTTTGACCTTCAAAACTGCTCCATGAAGTTCGGTTCTTGGACCTATGATGGCTCCCAGG[T/C]ATGTTTTTAATTATTATTAGACACCAAAAGCCAAATTCATGTTGTTTCTAAAAAAAAATTAGTTTTTTTTTTTATTTAAGTCGATTAAACATATAACAAATAAATAATATATATATATATATATATATATATATATATATATAGCTGTACGTTTTCAGAATGAGTCTAGGTTGGTTACATTTGATACATTTATCTGATTACTGTTATCTGATACATTTTTACAGCAGTTTAATTTAGTAAACATAATGAAAGGGTAGTAAATTTGCCCAGAGTGACATGTTGAATTTTTTTACAATTGTCTAAATATGGTTTGTCATCGAAAATCTTTCCGCTAGCTGAAACACAAAAAAAACTTATGGCCAAATTAAGACTCAAAATCACCCCAGAGTGGATGAAAACATCCCCAGCAGTACATAATGGTTATTACATGAATATTTATGCAGCAATTGAACAATCCTCTTCTTTTAAAGGTCGACATTCTCCTTGAAGACGTGCATGTG
Associated Phenotype:
Not determined