Busch Lab

ZMP

irx2a

Ensembl ID:
ENSDARG00000001785
ZFIN ID:
ZDB-GENE-040426-1446
Description:
iroquois-class homeodomain protein IRX-2 [Source:RefSeq peptide;Acc:NP_957351]
Human Orthologue:
IRX2
Human Description:
iroquois homeobox 2 [Source:HGNC Symbol;Acc:14359]
Mouse Orthologue:
Irx2
Mouse Description:
Iroquois related homeobox 2 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1197526]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa17696 Essential Splice Site Available for shipment Available now
sa22736 Nonsense Available for shipment Available now
sa10776 Nonsense Available for shipment Available now
sa19128 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17696
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000016303 Essential Splice Site 74 432 2 5
Genomic Location (Zv9):
Chromosome 16 (position 568818)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 542626
GRCz11 16 561858
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAAAAACACAAATWCAAGAACATTTGACTGRCCCCGAATKTTATTTTTGA[A/G]GGGCYCTCCGTATGACGCGCACACTACGGGAATGGCAGGAGCCAYAAGTT
Long Flanking Sequence:
AATTGATGAATTGCCATGCTAATGACATGGCACATGAAAGCGCGTGGAAAAAAAGCCAGTCCATATCCAGTGGTTTTCTAATAGGATTTGTAATGCTGCGCTTCACTGATATGCTTCTGACACTGAAAGAGCACTGGGAAAGTCAGCCTGGTGATTATGCAAAATGGCTGCAATTACCCATTATCTGTTATCCACCCCGGTCCCGTGTAATTGTGCATTCTGATAATTGCGTAGAGGATTAATCGTTGTTTATTGGCTTAATTATTATTAGTATTATATTTCTGGATACACTTTAGAATGGCGATCATTAATGACATTAACTTTATAAAAACGCAGAATGGATCATTGGTTAATTTGCATTTGAATTGTTTTATTATTATTATTATTATTATTCATCCTACATTATTTTTGTTTTAAATTAAGCTATTTATTTTTAAAGTGTTTGCAAAGCAAAAACACAAATACAAGAACATTTGACTGACCCCGAATGTTATTTTTGA[A/G]GGGCTCTCCGTATGACGCGCACACTACGGGAATGGCAGGAGCCATAAGTTATCACCCGTACGGGAGTCCCGGTTACCCGTACCAGCTCAACGATCCCGCTTACCGGAAAAACGCCACTCGGGACGCAACAGCGACGTTAAAAGCGTGGCTGCAGGAGCACAGGAAAAACCCCTATCCCACTAAAGGAGAGAAGATCATGCTGGCCATCATCACCAAAATGACCCTCACGCAAGTGTCCACCTGGTTCGCCAATGCACGACGGAGACTCAAGAAGGAGAACAAGATGACCTGGGCACCGCGGAATAAAAGTGAAGACGAAGACGAAGATGACGGAGATGGAGAGAGAAAAGACGAGCGCACGGATAAAAACATGGACAACAGCGAAGCGTCAGCTGAGGACGAAGGTGCGTTACTAATATTAATAATAATAATAACATCAGCTGATTTATTTTAAATGTATGACACTTTAAACAATGTATTGCATGGCATGAGATGTTATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22736
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000016303 Nonsense 159 432 2 5
Genomic Location (Zv9):
Chromosome 16 (position 568561)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 542369
GRCz11 16 561601
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATCACCAAAATGACCCTCACGCAAGTGTCCACCTGGTTCGCCAATGCA[C/T]GACGGAGACTCAAGAAGGAGAACAAGATGACCTGGGCACCGCGGAATAAA
Long Flanking Sequence:
TTAATTATTATTAGTATTATATTTCTGGATACACTTTAGAATGGCGATCATTAATGACATTAACTTTATAAAAACGCAGAATGGATCATTGGTTAATTTGCATTTGAATTGTTTTATTATTATTATTATTATTATTCATCCTACATTATTTTTGTTTTAAATTAAGCTATTTATTTTTAAAGTGTTTGCAAAGCAAAAACACAAATACAAGAACATTTGACTGACCCCGAATGTTATTTTTGAAGGGCTCTCCGTATGACGCGCACACTACGGGAATGGCAGGAGCCATAAGTTATCACCCGTACGGGAGTCCCGGTTACCCGTACCAGCTCAACGATCCCGCTTACCGGAAAAACGCCACTCGGGACGCAACAGCGACGTTAAAAGCGTGGCTGCAGGAGCACAGGAAAAACCCCTATCCCACTAAAGGAGAGAAGATCATGCTGGCCATCATCACCAAAATGACCCTCACGCAAGTGTCCACCTGGTTCGCCAATGCA[C/T]GACGGAGACTCAAGAAGGAGAACAAGATGACCTGGGCACCGCGGAATAAAAGTGAAGACGAAGACGAAGATGACGGAGATGGAGAGAGAAAAGACGAGCGCACGGATAAAAACATGGACAACAGCGAAGCGTCAGCTGAGGACGAAGGTGCGTTACTAATATTAATAATAATAATAACATCAGCTGATTTATTTTAAATGTATGACACTTTAAACAATGTATTGCATGGCATGAGATGTTATAAGATTTGATTGATGGATCTATTTCACTTTAAAATTGCAGGGTTGATGGTTCAAATATGTACAAAACCAATATTATGTTGAGTTATTTTTTATTTAAATTATACATTTTAACCCAACCGCTGTGTGTGTTTATATTTAACCCAAGATTTTAGCTCTAAGAAATGCTGGGTTATTTTAAACCCAAATTTAATACACTTCAGACTAATCCAAACATTGCGTTAATTTCGGCCCTATTTATTTAATTTAAAAATAACCCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10776
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000016303 Nonsense 260 432 3 5
Genomic Location (Zv9):
Chromosome 16 (position 567751)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 541559
GRCz11 16 560791
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGAAATCCAGGACAAATGCGAGGCGACGGATCTCGGGGAGGAAAGGCAG[C/T]GAGGCGCGTCACCCAAACCGGTGACCTCTTCTCCTYTGACCGGGGTGGAG
Long Flanking Sequence:
CAATATTATGTTGAGTTATTTTTTATTTAAATTATACATTTTAACCCAACCGCTGTGTGTGTTTATATTTAACCCAAGATTTTAGCTCTAAGAAATGCTGGGTTATTTTAAACCCAAATTTAATACACTTCAGACTAATCCAAACATTGCGTTAATTTCGGCCCTATTTATTTAATTTAAAAATAACCCAGCAGTGTGTGTACCCCGTATTACACCAATAATTATTAGAGTGCATTAACGCTAATATGGATTCATATTTCTAAAATGCATCAGTGCAATTTTATGACTGTTTTATTATTAGTTTTTAACGCAATAATCTCACTGCGGTGCCGCTTCTGTCTCCAGGCATCAGTTTGCACGTCGATGCCCTGACAGACCACTCGTGCTCGGTGGAGTCGGACGGGGAGAAGGTCACGTGTCGGACCGGAGACCTTGTTTGCGATTCTGGAGCTGAAATCCAGGACAAATGCGAGGCGACGGATCTCGGGGAGGAAAGGCAG[C/T]GAGGCGCGTCACCCAAACCGGTGACCTCTTCTCCTCTGACCGGGGTGGAGGCGCCTCTATTGACCCATCATCACCGGGAGAACAGCACCAACAAAACATGCCTGGACGGTCAAAACCAAACCGTCAAGCCTAAGCTGTGGTCATTAGCAGAGATCGCCACTTCGGACCCCAAGCAGCAGAACTGTCCCCCGGGTGTCGGCCTTCTGACCTCCAGCGCGCCCGGCGCGTCCCCGGCGGGCGCGGTTTACCCCGCCACCTCCATACTAGGAAGACCTCTTTATTACACTTCTCCGTTTTATAGTAATTACACAAACTATGGCAACTTCAGCCCGCTTCAGGGCCAGGGGATACTGCGCTACAACTCCGCCGCAGAGGGACTCCTTCATAAACAGACTGGAGAGCCGCTAATAAAGACTAATCCAAACCAGACTGAAGCTCACTTCAGGGCCTCCAATGCAGAATCCAAAAAAGGTGCGTAGGCTGTTAATCTCTGACAGCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19128
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000016303 Nonsense 429 432 4 5
Genomic Location (Zv9):
Chromosome 16 (position 566835)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 540643
GRCz11 16 559875
KASP Assay ID:
2260-9074.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATTTCCTGCAGACCCCAGCGAGGTTTTCACAGTAAGATCCCAATCTTA[C/A]CTGTCGAGTTAAGACGAGGAAGATCTTCCAAGTAAGTCGCTAATTTGAGC
Long Flanking Sequence:
TAATCCAAACCAGACTGAAGCTCACTTCAGGGCCTCCAATGCAGAATCCAAAAAAGGTGCGTAGGCTGTTAATCTCTGACAGCTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATTAGACCCTTTTTACAGAATCGGTCGCGGTTTTAAAATGATTTCAACGCAAATTGTGTATGCATAAACTGCTGGATTGTTAATTTCAATTCATTCATAACCAGATTGATTGAGTTTGTCTTATATTCTACCTTAAATTGTGTTTAAAAAACTTATAAATGTTAACCAGATTCCGCAGTTCCCTCGTTTATATTGTTGTTTGCACTTGACATGCATTTCCCCTACTGTTTATTCCCTCAATCGATCGCGGAATACGAAGTAGCCCATTTAAGCTGTCAAAACGATTCCCTTCACTAAATTGGGTGTGTATTTCCTGCAGACCCCAGCGAGGTTTTCACAGTAAGATCCCAATCTTA[C/A]CTGTCGAGTTAAGACGAGGAAGATCTTCCAAGTAAGTCGCTAATTTGAGCATTTCAGTGCTGATTATTATTATTCTGTATGCTTCTGAAGGCCACGTCCTCATATTTGACACCTGTCAACATACGCTATAAATAATGCTGAGATGTTTTATCCAAATATTGGATTTATTTTTTATTTTTTTGTAATTAAATTTATTTTACGATTTTGCTTTTTGCAAATTTGTCCTTATCTGACCCAGCGTTGGGTTACAATAACCCAGCATATTTAGAGTGCATGAATATGACACTTCCCATCGACTCAAAGGTTGCTTCATGAAGTGTGTGTATTTCTAAATGTCATGCTGTAGTTTTATTTCATTCACTTTCTCTGGAAAAATCGACTGATGTAGGTTTTGTTTCCTTGGTTCACAGGTAGGTGTCACAATTGCTTTGAACAAAGCGAACAAGCCATCACCCCTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCT
Associated Phenotype:
Not determined