ZMP
srsf1a
Ensembl ID:
ZFIN ID:
Description:
Serine/arginine-rich splicing factor 1A [Source:UniProtKB/Swiss-Prot;Acc:Q7SXP4]
Human Orthologue:
SRSF1
Human Description:
serine/arginine-rich splicing factor 1 [Source:HGNC Symbol;Acc:10780]
Mouse Orthologue:
Srsf1
Mouse Description:
serine/arginine-rich splicing factor 1 Gene [Source:MGI Symbol;Acc:MGI:98283]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa35834 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa22604 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa35834
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000080413 | Essential Splice Site | None | 257 | None | 5 |
| ENSDART00000133755 | Essential Splice Site | None | 193 | None | 4 |
| ENSDART00000135658 | None | None | 117 | 1 | 2 |
The following transcripts of ENSDARG00000057691 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 15 (position 15095366)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 16140329 |
| GRCz11 | 15 | 16076351 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGGAAACACGCTCTCGGTGTGCGCGTGCGAGCGGTGCTTCAAACAATAG[T/C]AAGTCTCTTTGTTTTAAATCTAATGTTGGTTGCGGTTTATTTACCGTATT
Long Flanking Sequence:
CCTGCTGTAAACTGGATTCTGCTTTGGTCTACTTTTTTATTTTATTTAATTTTTTTTTACAATTTTAATAAATAATTTGTGAAAATACATTGTTTCATTGTTAAATTTCTCTAACTTCATATCTATCTTGCACAATAATCCTGCTGGAACTGTATATTTAAATAGACCTGTAGGTTAATTCCTGCAGGAACCAATTAATTCCTGCATGCAACCAATTAAATGTAGCATAGACTTCAACTGAGGACCACTCTGTTGTAAAAAATAAAATCTTTACAGAACTCATTCACACTACACGCCAACATAGATCCGCTGTATCTTTGCAGACGTCGCTATAATGATTATTTCGTGTCGCGGATGTAGCCGCTCCACTCCCCGCCGAGCCTGTTTGTTCAGATTCCTCCGCGGCTGGTAAAGCGCGCCCGCTGAAGAGGAAGCGACCGCGCGACTTCAGAGGAAACACGCTCTCGGTGTGCGCGTGCGAGCGGTGCTTCAAACAATAG[T/C]AAGTCTCTTTGTTTTAAATCTAATGTTGGTTGCGGTTTATTTACCGTATTTCGCGAGGCACACAAATAGCCGTTGTTTATCAGACTCGAAAAGCGTTGTTTGTTTCTCTGTTCAGCAGGAAGGTGAAGATTTGTCAGTGCAGAGATGTCCGGTGGTGTGATCCGCGGCCCTGCTGGAAGCAACGATTGCCGCATCTATGTGGGAAACCTGCCGCCCGATATTCGCACCAAAGATGTCGAAGATGTGTTTTATAAGTACGGAGCCATCCGAGACATCGATCTGAAAAACCGACGAGGCGGACCTCCATTCGCCTTTGTCGAGTTTGAAGACCCCAGGTGGGTGAAACTGAACCTTGAGCTCGTAGCCTTTAGCTAAGCGGCTAACTTAGTTTGTCCGTTTGTTTCAGCGTTACCCAAATTATTTATAAAACTTGTCACCGTTAATAAACGTGTAACGTTTGCCAACGCGTTTTTACAATCTTCGCATGCACAGTAGTGTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22604
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000080413 | Nonsense | 233 | 257 | 5 | 5 |
| ENSDART00000133755 | None | None | 193 | None | 4 |
| ENSDART00000135658 | None | None | 117 | None | 2 |
The following transcripts of ENSDARG00000057691 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 15 (position 15092374)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 16137337 |
| GRCz11 | 15 | 16073359 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAGGAGCCGCAGTCGCAGCAGGAGTCGCAGCCGCAGCAACAACCGTAGC[C/T]GAAGCTACTCTCCACGCCGCAGCCGAGGATCCCCGCAGTACTCGCCACGT
Long Flanking Sequence:
TTTCTCTGGATTTGTGGTTTAGTTCTGTTTTTGAAACAATGTTTTAATATGTGATTTAGACTACATGATCAATCTTTTTAACTGAACTTTTTATTTTTATGGTAATAGTAATTCTCAGTTAAAACAATCTTATTCTGACCAATAGTTTTTGTACAAAGTTTTTGAATAACTTTCCCTATAAAAAAATTAGGAAATGCGCTCTCAATATTTTTCAAACCCATACCTAGTCAATCCAGAGAAACTGACCAAATAATTTAGTTTTAAGTAATATGATTAAAGCGAAACCAAAGATATGTTTGTTCCAGGAAGTCTGGTAAGTACAGTGAAAATGTTGGCCTATTTGTACTATGCACTTGCTCAGCGGAAAGTTCTTTGTCTGCCAGGGAGAAACTGCGTACATCCGCGTAAAGGTGGACGGACCCCGCAGTCCAAGCTATGGAAGATCAAGGTCAAGGAGCCGCAGTCGCAGCAGGAGTCGCAGCCGCAGCAACAACCGTAGC[C/T]GAAGCTACTCTCCACGCCGCAGCCGAGGATCCCCGCAGTACTCGCCACGTCATAGCCGTTCCCGCTCTCGCTCCTAAAGCGCTCCACTCTTCACCTCATTGGTGGAGCCCTTGAGTCGTTTTTGTTTTACAGTCTTTACAAATCACGAACCCCATGTTTTAATCACCCCCTGTTTCGTGAGACAGTTGATCTTATGAATGTTGTCTTTTTTTTTTTTTTCCCCTCCCTCTTACTGTTAGTTTTAAACATGCGTTTTTAACTGAACCCATTTTGTTTTTCCCCCCCATCCATTTTTTTTTTCAATACATAGTGGAAGTCTTTCATAGATCAGATCAAGGATTATGTAATGACTCCCAAATATTTTTGTAAATGCCATGTATGAAAGTTAATCATGGGATAGTGGGTTCCACAGTTGTTTTATGCTGTCTTCCTCTAGACGTGACACAGATCTGATGCTTTGTAATAAAGGATTACTAAATCTATACTTTGTTTCGTAAAAG
Associated Phenotype:
Not determined