Busch Lab

ZMP

gria2b

Ensembl ID:
ENSDARG00000052765
ZFIN ID:
ZDB-GENE-020125-4
Description:
glutamate receptor, ionotropic, AMPA 2b [Source:RefSeq peptide;Acc:NP_571970]
Human Orthologue:
GRIA2
Human Description:
glutamate receptor, ionotropic, AMPA 2 [Source:HGNC Symbol;Acc:4572]
Mouse Orthologue:
Gria2
Mouse Description:
glutamate receptor, ionotropic, AMPA2 (alpha 2) Gene [Source:MGI Symbol;Acc:MGI:95809]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa44813 Nonsense Mutation detected in F1 DNA Not yet available
sa22520 Nonsense Available for shipment Available now
sa35727 Nonsense Mutation detected in F1 DNA Not yet available
sa1498 Splice Site, Nonsense Available for shipment Available now
sa39009 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa10318 Nonsense Available for shipment Available now
sa42424 Essential Splice Site, Missense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa44813
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 Nonsense 8 879 1 16
ENSDART00000074671 Nonsense 8 897 1 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 36968919)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35408246
GRCz11 14 35748560
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTGGCTGAACACACACTGTCGAGGAGATGCAACAGTTGAAGAATTTAT[C/A]GATTTGTCTCATAGCCCTCTTATTAGGGATGACAACTGGAGGCTCTCCAA
Long Flanking Sequence:
AACTAATGTAATTAGTCAACAAACTGTACATTATTTTAAAGTGCTACTAACAAAATCTGCTAATATGCTACTAAAAATGCCTGTAGCCAAAACAAACAAAAACAATTAAGAATGTGGCACGTGCAACTGATGCGCCTTTATTCCTGAGCCTGTATTCATGTCTCGTTATTAGTCGCCGCTGTGACAGCTGCGTTGCTCCTGTATGTTAGTAAAGGTATCAACTCACAGAAAGGCGCGCGACTCGAGGGAGGAGAGAGAGAGAGGAGAGAGAGAGAGAGAGAGAAGGAAAGAGAGAGAGATAAATCTGCATTATTCCTCCAGAAGCGGGACTGAGGCAGGAGTCCGCGATAGAGGAACCACCTGCAGACCGCAGCCGCTCTCATTCTCAGCAACGCCTCAATATGTTACGGATTTGACTCATACTGTAAACGACAGATTATTTCCTTCACACAGTGGCTGAACACACACTGTCGAGGAGATGCAACAGTTGAAGAATTTAT[C/A]GATTTGTCTCATAGCCCTCTTATTAGGGATGACAACTGGAGGCTCTCCAAGTGTTCAAATCGGTACGCGCGTCATTCATTTAATTTTTTAGTTTTGTTAAACTAGCGTTTGTAATAGACGTGAACTAAGAATTCATAAGCTGTATTTGTGTGTGTCGTACAGGAGGCTTGTTTCCGAGGGGAGCCGATCAGGAGTACAGCGCGTTTCGGATCGGAATGGTTCAGTTCGGAACGGCTGAATTTAGACTGACGCCTCACATCGATAATCTGGAAGTAGCAAACAGTTTCGCTGTAACTAACTGCTGTAAGTTGTCTTGTTTTTCTACATCAAATGCATGTGATCGCTTTTTTGGTTTTTGAACAAAGGCAGAATTTGGCTATTGAGAATGAGTGGTTTGTGTGCTGAAGTTTGAGTGCGGCTTATGGTAGGAATTTGTGTATAGCTGGATGTGAAGTTGGTTTCCACAGTAACGGAGACGAGGACGAGCTCCCATCATCGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22520
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 Nonsense 250 879 6 16
ENSDART00000074671 Nonsense 250 897 6 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 37016425)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35455752
GRCz11 14 35796066
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGCCATTTCATGTTTTTAGGGTTTTGTGGATGGAGATCTTTCTAAAATC[C/T]AGTATGGTGGAGCGAATGTGTCAGGCTTTCAGATTGTGGATTTTGATGAC
Long Flanking Sequence:
GGAGTCAAATCGAAACCGCTATATCTGTCTAAAAAAAAAAAAAAATAAAAAAAAAAAATAATAATAATAATTCACAATCAGATATTTTCCCCAAATCATCAAGCCCTACTTTGGATGTTTATTTGCAACTATGAGAAATAAAAATACAATTCCAAGAAGAAAAGTCCCAATTGTGAGACTCATGATTGCATGAAAAAACTGTATTCTGAGGTTATTCAAAATCCAAAAAAAAACTAAAAAAAACTTTAAATATTAGCTTTTAGTATTTCTAGTGTGTTTATTTTGTAATGCATTGATTAAATGAGATCTTTTATTCTCTTCCCAGGTCATTACTATTGGCAGGCATGTGAAGGGATATCACTACATCATAGCAAACCTGGTAAACTCAAATACAGCACTAACAACAAAAAAAAAAACATCACATTTTTAAAATAGTAGCAATCAAAACAAAAGCCATTTCATGTTTTTAGGGTTTTGTGGATGGAGATCTTTCTAAAATC[C/T]AGTATGGTGGAGCGAATGTGTCAGGCTTTCAGATTGTGGATTTTGATGACCCTCTGGTGTCCAAATTTGACCAGCGCTGGGAAGCTCTGGAGGAAAAAGAATATCCTGGAGCAGACAGCAAGATACGGGTGAGACCTCTGTCTGTGTGTGTGTGTGTGTCCATTTCAGACATCTTTCCTAAGTATGATTAAAAGAGATGTTCAGGTAATTGCTACATGAATGTATAACCTCTTCATTTAAAAGCCCGTATACTTCAGGCCATTTGCAGGAAAAGCTTGTTAGTTATTTTCTACTCCAGATTAAATGTGGTCTCATCTGTCTCGAAGACTAAGCAGGTGCTTCATTTCTGCAGACTGAAATCAAATGTTTCATTTTTTAAATTAGCAAATAAGTCCTGTATAAGTGACATTTAAAACTGAGAATTCCCTTTAAATTCTTTCCTAAATTTGATTTGAATGTAGAATATGATTTATGTTAGTAAAATTCAAATGTATCGAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35727
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 Nonsense 377 879 8 16
ENSDART00000074671 Nonsense 377 897 8 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 37019760)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35459087
GRCz11 14 35799401
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGACCAGTATGGAAAGAGAGTGAATTACACCGTCAATGTCATGGAATTG[A/T]AAAGCAACGGAGCAGTTAAGGTAAGACTCAGTCCTAATAATGCACTTGCA
Long Flanking Sequence:
TACAAATGTCGTTAACAAGCAGTTGAATATAAAGTGGCCGGTGAGTGTATTTGAAAATGTTCATGTCAGAATATGTTGTTTTGTTTATACTGTACATATACTGTACATGTTGTGCTGAATGATGATTTAATATTGTATGTATCAACTTGCTTTTAATAAGCTTTCTGTGTATAGAAAATACTTTTAGCAAATTTAAACACCAAAATGTACTTCCCATCTTTGACCATCATTATCAGAAGAATACATCTTTGTTTAAAATACTCAAAGATTTTTAACCTATAAATGTTTAAAATAAAACTTTGAAGCTTTGTGTAAGATTTGAAGCAAGTCATTTTTGAAGCCTGCTTCATGTTTTTAACATTTCCCAGAATAACTAAAAACTGTTTTTCTTCCTCTGTCATATCCATTTCATGCAGGTGAGAGTTGATGGTCTCACTGGTAACATTCAGTTTGACCAGTATGGAAAGAGAGTGAATTACACCGTCAATGTCATGGAATTG[A/T]AAAGCAACGGAGCAGTTAAGGTAAGACTCAGTCCTAATAATGCACTTGCAAAGCATCATTTTATCAATTTACTCTCTATAGTGATTATTTCAGATTGGCTATTGGAACGAAGTGGATAAAATGGTCGTCACAAAATCAGATCTCTTCCCAAATGACACAATGGGGCTTGAAAACAAGACTGTGATCGTCACCACCATTCTAGTAGGTTTTACTTGTGGTCGTCCAACATATTATTAAGTATTTTTTAGTAAAGCACTACTCTCTGACAAGGTGTTTCCTGGTGTCTTTTTCAGGAAGCCCCATATGTAATGTTAAAGAAGAATGCTGACCTTTTTATGGATAATGAAAGATATGAGGGGTATTGTGTGGACCTGGCAGCTGAAATAGCAAAGCACTGTGGATTTAAATATCAGCTGAAAATAGTAGGCGATGGCAAATATGGAGCTAGAGATGCAGAGACGAAGATCTGGAATGGAATGGTTGGAGAATTGGTTTATGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1498
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 Splice Site, Nonsense 489 879 11 16
ENSDART00000074671 Splice Site, Nonsense 489 897 11 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 37020387)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35459714
GRCz11 14 35800028
KASP Assay ID:
554-1423.1 (used for ordering genotyping assays)
KASP Sequence:
GTTAAAAATATAATTTAAGAATTAAACCGAAATTAAATCTCTCGTTTCAG[A/T]AAGCTGACATCGCAGTGGCTCCACTGACTATCACTTTAGTCCGAGAAGAA
Long Flanking Sequence:
GTCACAAAATCAGATCTCTTCCCAAATGACACAATGGGGCTTGAAAACAAGACTGTGATCGTCACCACCATTCTAGTAGGTTTTACTTGTGGTCGTCCAACATATTATTAAGTATTTTTTAGTAAAGCACTACTCTCTGACAAGGTGTTTCCTGGTGTCTTTTTCAGGAAGCCCCATATGTAATGTTAAAGAAGAATGCTGACCTTTTTATGGATAATGAAAGATATGAGGGGTATTGTGTGGACCTGGCAGCTGAAATAGCAAAGCACTGTGGATTTAAATATCAGCTGAAAATAGTAGGCGATGGCAAATATGGAGCTAGAGATGCAGAGACGAAGATCTGGAATGGAATGGTTGGAGAATTGGTTTATGGGGTAAGAAAGATTTTTTAGATGTGATTGAAAATGAGTCGAAAAAATAGCTTCAAGCACTAAGCTCAAGGATATATTGGTTAAAAATATAATTTAAGAATTAAACCGAAATTAAATCTCTCGTTTCAG[A/T]AAGCTGACATCGCAGTGGCTCCACTGACTATCACTTTAGTCCGAGAAGAAGTTATCGACTTCTCAAAGCCGTTCATGAGTTTGGGCATCTCCATCATGATCAAGAAGCCTCAGAAGTCCAAGCCTGGTGTTTTCTCATTCCTGGATCCACTGGCTTATGAGATCTGGATGTGTATTGTGTTCGCTTACATCGGTGTAAGTGTGGTGCTTTTCCTGGTCAGTCGTTTCAGTCCATATGAGTGGCACACAGAGGAATATGAGGATGGACAGATCCAGACCAACGAGTCGACCAATGAGTTTGGGATCTTCAACAGTCTTTGGTTCTCTCTTGGAGCTTTTATGAGACAAGGATGTGATATTTCACCCAGGTTTGTTTGTGATCTTGATTTCTTCAAGAAATGTTGAATTTGTAAAAGTTTTGAATGATTTCGTATGTAAAACAAAGGTTAGATTTGCAGTCATTTCATCATTAGATTGCTAAGGGTAACCTTAGATAAAGTT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa39009
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 None None 879 None 16
ENSDART00000074671 Essential Splice Site 798 897 14 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 37026457)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35465784
GRCz11 14 35806098
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATGGTGGTACGACAAGGGAGAGTGCGGCAGCGGGGGAGGTGATTCCAAG[G/A]TCAGCCCCAGAGAGCAAAGTGATGGGTAACTCAATGCAACACTCAAGTAA
Long Flanking Sequence:
GAACAGCAGTCTGTTAAGAACTGGGTGGGTGGGCTTTAGGAGAAGATTGAATTATGCATGATAAAGTTATAACCGACTTTTATAGCTGTTCTGCTGTCCTTCTAGTAATGTTACTCGCAGGCCACTGCTATTAGTTATTAATGTGAGTACTGCGTTAAGCTTCTCTATTCACGGCACTCTGAGCCACCTTTATCACCTTAAAAACGTTTGATGCTATTAGTTGATTTGTTTTCTAACAATTTCACATTTTGTAAGGGAGGAGATGATTTCTTATTTGTTAAAATGCTGAAAAAGAGGAAAAGCAATCGTTAGGTTTGAAAGAGGACCATTGACAATTGCTAAGTTGGCTCACCCTGTCTTACAAGTTATGTTTTATCGTTTCAAGAAATGCGGTTAACCTCGCAGTACTAAAACTGAATGAACAAGGCCTGTTGGACAAATTGAAAAACAAATGGTGGTACGACAAGGGAGAGTGCGGCAGCGGGGGAGGTGATTCCAAG[G/A]TCAGCCCCAGAGAGCAAAGTGATGGGTAACTCAATGCAACACTCAAGTAAGCAGCAAAACCGCACAGGAACCAAAAGTCTGAAGATGGACGTTCTTTACACAACACTGACAGGTTTAGCATTGCTAACCATTGCTAATGAACACACACACACCCACATAAACAAAAGCTTCAAAATTCTCAGATTGGTCATCGTGTGCAGCACACATGGCTGTTGCCCTTGCTGCTTACTTCAGGCGATACGTTAATGCACATTTGGCTCTGCAAAACTTGCATTTGCTTAGGCCAAATGGCGCATCAACGTCATAATCGCTATGGCAATGAAGAAAAGAGGAGAGAAAAGGTGAAATCTAAGAGAAAGTGAAATCAGTGTGATGTAATAATAACATAAAATAACATTGATAATGTTATTTATGTTATTTCCCACGTGAAGAACGCCAGTAAACCTTGCAGTATTGAAACTCAGTGAGCAAGGCACCTTAGACAAGCTGAAAAACAAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10318
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 Nonsense 838 879 15 16
ENSDART00000074671 Nonsense 838 897 15 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 37030569)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35469896
GRCz11 14 35810210
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTTGGCCATGCTGGTGGCCCTGGTCGAGTTCTGTTACAAGTCCCGAGCC[G/T]AGGCCAAGCGCATGAAGGTGGCAAAGAATGCACAGAATATTAATCCCACT
Long Flanking Sequence:
ATTAACCCCTGCTATAAATGTGAATTCAACAAAGAGAATATTTACTACAGCCATTAGCACGAGGAAATGTAAGAAGTGTGATTTAAAAGCGCTTTGTTGCTTTGGTAGCCATCTCTCAAGAGAATGTTAAAGGCTTTAGTAAATCCATCCCATTCGAGCAGAATTGCTCAATGCCCCCCCATTGCATTGCTTCAAGGGCACATTAACCAGCAGCTGCAGCAGCACAGTTATTGTTTAAACATTACTGTCCTGAGCTGTGCATTTGTATCCACATAGACGTAAAATTGCCACTTAAATATTCTGTTATTTCTACATTTGAATGTTTAATACTGAGATGGTGTGCTTTCCCCGAGCGCTGACCCGTGTCTCGTGTGCATTTTCAGGAGAAGACCAGCGCGCTCAGCCTGAGCAATGTGGCTGGCGTCTTCTACATCCTTGTGGGCGGCCTGGGCTTGGCCATGCTGGTGGCCCTGGTCGAGTTCTGTTACAAGTCCCGAGCC[G/T]AGGCCAAGCGCATGAAGGTGGCAAAGAATGCACAGAATATTAATCCCACTTCCTCGCAGAATTCACAGAATTTTGCCACTTATAAGGAAGGGTACAACGTATATGGGATCGAAAGTGTAAAAATTTAAGGGGGTAGGATACGCGGCCGTCATTTCAGTCTGTCCCGTGCACGCTTCTTTTGGCTTCCCATCTGTTCCATTCCCTGAATGTTCTAGTGAATGAGGAGATTTGGACCGTAAACTGGATCGTATGTACTGGTGTTCTTATAGTGATAAAAAAGAAAAAAAAACTTCCTTTCTCCGCCTCTGCTGCACATATATACAGGAGAAAAGTTTTTTTTTTGTATACCAAGTGACTTTGTTCGTCCACCTCATTGTCATGTATGACTGTTGTTATATCCTACATCACTATGGGAAGCTTAAATCCGCCATCGAATTTAAAAAAAGATTTCAGTGCGACTGTATCTCACAAATAATACTTTTTTTCACCTACAATATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42424
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064617 Missense 844 879 15 16
ENSDART00000074671 Essential Splice Site 843 897 15 16

The following transcripts of ENSDARG00000052765 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 37030587)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 35469914
GRCz11 14 35810228
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCTGGTCGAGTTCTGTTACAAGTCCCGAGCCGAGGCCAAGCGCATGAAG[G/A]TGGCAAAGAATGCACAGAATATTAATCCCACTTCCTCGCAGAATTCACAG
Long Flanking Sequence:
TGTGAATTCAACAAAGAGAATATTTACTACAGCCATTAGCACGAGGAAATGTAAGAAGTGTGATTTAAAAGCGCTTTGTTGCTTTGGTAGCCATCTCTCAAGAGAATGTTAAAGGCTTTAGTAAATCCATCCCATTCGAGCAGAATTGCTCAATGCCCCCCCATTGCATTGCTTCAAGGGCACATTAACCAGCAGCTGCAGCAGCACAGTTATTGTTTAAACATTACTGTCCTGAGCTGTGCATTTGTATCCACATAGACGTAAAATTGCCACTTAAATATTCTGTTATTTCTACATTTGAATGTTTAATACTGAGATGGTGTGCTTTCCCCGAGCGCTGACCCGTGTCTCGTGTGCATTTTCAGGAGAAGACCAGCGCGCTCAGCCTGAGCAATGTGGCTGGCGTCTTCTACATCCTTGTGGGCGGCCTGGGCTTGGCCATGCTGGTGGCCCTGGTCGAGTTCTGTTACAAGTCCCGAGCCGAGGCCAAGCGCATGAAG[G/A]TGGCAAAGAATGCACAGAATATTAATCCCACTTCCTCGCAGAATTCACAGAATTTTGCCACTTATAAGGAAGGGTACAACGTATATGGGATCGAAAGTGTAAAAATTTAAGGGGGTAGGATACGCGGCCGTCATTTCAGTCTGTCCCGTGCACGCTTCTTTTGGCTTCCCATCTGTTCCATTCCCTGAATGTTCTAGTGAATGAGGAGATTTGGACCGTAAACTGGATCGTATGTACTGGTGTTCTTATAGTGATAAAAAAGAAAAAAAAACTTCCTTTCTCCGCCTCTGCTGCACATATATACAGGAGAAAAGTTTTTTTTTTGTATACCAAGTGACTTTGTTCGTCCACCTCATTGTCATGTATGACTGTTGTTATATCCTACATCACTATGGGAAGCTTAAATCCGCCATCGAATTTAAAAAAAGATTTCAGTGCGACTGTATCTCACAAATAATACTTTTTTTCACCTACAATATATAGTTTCATAGATAGTCTCA
Associated Phenotype:
Not determined