Busch Lab

ZMP

rps6kal

Ensembl ID:
ENSDARG00000037574
ZFIN ID:
ZDB-GENE-030131-9616
Description:
Ribosomal protein S6 kinase alpha-6 [Source:UniProtKB/Swiss-Prot;Acc:Q6PFQ0]
Human Orthologue:
RPS6KA6
Human Description:
ribosomal protein S6 kinase, 90kDa, polypeptide 6 [Source:HGNC Symbol;Acc:10435]
Mouse Orthologue:
Rps6ka6
Mouse Description:
ribosomal protein S6 kinase polypeptide 6 Gene [Source:MGI Symbol;Acc:MGI:1914321]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa22425 Essential Splice Site Available for shipment Available now
sa42349 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18445 Nonsense Available for shipment Available now
sa38980 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa22425
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047993 Essential Splice Site 108 740 None 22
ENSDART00000047993 Essential Splice Site 108 740 None 22

The following transcripts of ENSDARG00000037574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 9051426)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 8655908
GRCz11 14 8961922
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCGGCCAGCTTTATGCAATGAAGGTGCTCAAAAAGGCATCTTTAAAAGG[T/C]CAGCGAGTGTCTTCATCAGTGTGAGTAGTTAGTCAGCACATTTCCAGTGT
Long Flanking Sequence:
AACTGTTTGACCCGAGGGAAGATAAATTAGACTTTTTTCCCCAAAAAAGAGGAACATTGCTTTATTATTTTGTTTATAATGTGTTTAGTACCAAAAGTCATGTGTCCATATTTGGTCTTTGGCTTACAACTTACTTTGCAACCTAAATGTGTGGCTCTAGGTAACTAATGTGCTTTTGGCCTGTCATTAAAAGGGTCATATAGATTTGTTTTTACTGTTTTACTACTTCAGAAACATCACAGTGCCATGAAAACAGACCACGTTATGCATTGTGTTATCCAGTGGAGTATTTAATTGGACACTTATTAACTTCAGGTGCTAACTACATGTTGTAAACAATTATTTATGCTGGTGTTAGGAAAATTGTATGTCCAGTTTTTGTATGTCTATTTAAACAGTAATGTAAACTTTCCTCAGGTGTTTTTGGTGCGGAAGTTGATGGGTCCAGATGCCGGCCAGCTTTATGCAATGAAGGTGCTCAAAAAGGCATCTTTAAAAGG[T/G]CAGCGAGTGTCTTCATCAGTGTGAGTAGTTAGTCAGCACATTTCCAGTGTTGTTGTTTACCAATGTGTGTTGTCTTGCAGTGAGGGACAGAGTTCGCACTAAAATGGAGAGAGATATTTTGGTGGAGGTCAATCATCCTTTTATTGTGAAGTTGCACTATGGTAAGACTCAATTTGATGGATTTTATAAGTTACACTATGTAATCGTTTACACCAATGTTTTATTGTTTAAGTTTAGCTTTAATTAGTAAAGCAATTTCTATTTTATTCATATTCGTATTTTTATTCATTCGTATTTTATTCATTCAGAAAGATTCTTAAAATACGCATCCATGACCGAAATGTGACCTCTGGTGGACAGTAGCAAACTCTGAAATGAGAAGCAGATTCCTAGTTCCACATGAGGTGGTTATTAAATATTACAAATGTAAACATTAGGTGAGCAGGTTTCGCTGTAAGCTTGTATCCTAACAACATGCTTCATGATGAGATTTGCAGTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42349
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047993 Essential Splice Site 108 740 None 22
ENSDART00000047993 Essential Splice Site 108 740 None 22

The following transcripts of ENSDARG00000037574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 9051426)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 8655908
GRCz11 14 8961922
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCGGCCAGCTTTATGCAATGAAGGTGCTCAAAAAGGCATCTTTAAAAGG[T/C]CAGCGAGTGTCTTCATCAGTGTGAGTAGTTAGTCAGCACATTTCCAGTGT
Long Flanking Sequence:
AACTGTTTGACCCGAGGGAAGATAAATTAGACTTTTTTCCCCAAAAAAGAGGAACATTGCTTTATTATTTTGTTTATAATGTGTTTAGTACCAAAAGTCATGTGTCCATATTTGGTCTTTGGCTTACAACTTACTTTGCAACCTAAATGTGTGGCTCTAGGTAACTAATGTGCTTTTGGCCTGTCATTAAAAGGGTCATATAGATTTGTTTTTACTGTTTTACTACTTCAGAAACATCACAGTGCCATGAAAACAGACCACGTTATGCATTGTGTTATCCAGTGGAGTATTTAATTGGACACTTATTAACTTCAGGTGCTAACTACATGTTGTAAACAATTATTTATGCTGGTGTTAGGAAAATTGTATGTCCAGTTTTTGTATGTCTATTTAAACAGTAATGTAAACTTTCCTCAGGTGTTTTTGGTGCGGAAGTTGATGGGTCCAGATGCCGGCCAGCTTTATGCAATGAAGGTGCTCAAAAAGGCATCTTTAAAAGG[T/C]CAGCGAGTGTCTTCATCAGTGTGAGTAGTTAGTCAGCACATTTCCAGTGTTGTTGTTTACCAATGTGTGTTGTCTTGCAGTGAGGGACAGAGTTCGCACTAAAATGGAGAGAGATATTTTGGTGGAGGTCAATCATCCTTTTATTGTGAAGTTGCACTATGGTAAGACTCAATTTGATGGATTTTATAAGTTACACTATGTAATCGTTTACACCAATGTTTTATTGTTTAAGTTTAGCTTTAATTAGTAAAGCAATTTCTATTTTATTCATATTCGTATTTTTATTCATTCGTATTTTATTCATTCAGAAAGATTCTTAAAATACGCATCCATGACCGAAATGTGACCTCTGGTGGACAGTAGCAAACTCTGAAATGAGAAGCAGATTCCTAGTTCCACATGAGGTGGTTATTAAATATTACAAATGTAAACATTAGGTGAGCAGGTTTCGCTGTAAGCTTGTATCCTAACAACATGCTTCATGATGAGATTTGCAGTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18445
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047993 Nonsense 335 740 13 22

The following transcripts of ENSDARG00000037574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 9071616)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 8676098
GRCz11 14 8982112
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GATGTTTTWTTGGAGTATCATGTGTTTATTGTGTCTGTGTAGAARTTGTA[C/A]CGAAGAGAACTTCAGCCTCCATTCAAACCTGCTTCAGGGAAACCAGATGA
Long Flanking Sequence:
AAGGACTCAATTAGTTTGATCAGGTGTGTTTAATTAGGGTTGGAACTAAACTCTGCAGATCTCTGGCTCTTCGGGAGCTGGCTTTGTTATCGGTGCTTTAAAGCATTGGTCTCAAACTTAATTCCTGGAGGGCCACAGCTCTGCACAGTTTTGCTCCAATCTTCATCAAACACAGCTAATCCAATCAATGAATGTGTTTATTGGTCCCTACTCAGTATTGATTTTCAATTGGAAGTACATCAACATACTGAAATAAGTCAATTTCCTGTTAACACAGACTTTAAAGTTGCAGTTTAAATGACGAGCTTTTTAGTACCTCGTGTAAAGGCTTCGCATCTTTTGTCTGAAACCAATTCTATATTTGTGAATGACCTGGCTTATTGTGAAGTACAGTGGGCTGTCAGTGTGGAATGATAAGTGATCACTATTTTGTCGGTGTGTCAGGTGGGAGATGTTTTTTTGGAGTATCATGTGTTTATTGTGTCTGTGTAGAAGTTGTA[C/A]CGAAGAGAACTTCAGCCTCCATTCAAACCTGCTTCAGGGAAACCAGATGACACTTTCTGCTTCGACCCAGAATTCACAGCCAAAACTCCCAAAGGTATAAAAGAGAAAGTCTTTTGGATGGATTTCTTTGGGGGAACTAGTGATAATAAATGTACCTGTTAGAAGTGCGATAGTGAGTTGAGCTGTTTTGTGTGTGTGTTTTCCTGTCGACAGACTCTCCAGGCATTCCCCCCAGTGCAAACGCTCACCAACTCTTTAAAGGCTTCAGTTTTGTAGCCCCAGTCTCCCTGGAGGAAAGTAAAAGTGCGCCACTAGTCAACATTCTCCCCATAGTGCAGGTAAATCTCTCTCTTTTACTATGCATATGTGTGAATTATACATGTTTGGTGTTCTCTTTTTAAATTTAATGGTAAAAAAATCATGTAAAAGTTTAATGTAATGAAAATGTGTACAGTGGATCCAGAAAGTATTCATAGCGATTCACTATTTCCACGTTTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38980
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047993 Essential Splice Site 408 740 14 22

The following transcripts of ENSDARG00000037574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 9071956)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 8676438
GRCz11 14 8982452
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAGGAAAGTAAAAGTGCGCCACTAGTCAACATTCTCCCCATAGTGCAGG[T/A]AAATCTCTCTCTTTTACTATGCATATGTGTGAATTATACATGTTTGGTGT
Long Flanking Sequence:
TGTCTGAAACCAATTCTATATTTGTGAATGACCTGGCTTATTGTGAAGTACAGTGGGCTGTCAGTGTGGAATGATAAGTGATCACTATTTTGTCGGTGTGTCAGGTGGGAGATGTTTTTTTGGAGTATCATGTGTTTATTGTGTCTGTGTAGAAGTTGTACCGAAGAGAACTTCAGCCTCCATTCAAACCTGCTTCAGGGAAACCAGATGACACTTTCTGCTTCGACCCAGAATTCACAGCCAAAACTCCCAAAGGTATAAAAGAGAAAGTCTTTTGGATGGATTTCTTTGGGGGAACTAGTGATAATAAATGTACCTGTTAGAAGTGCGATAGTGAGTTGAGCTGTTTTGTGTGTGTGTTTTCCTGTCGACAGACTCTCCAGGCATTCCCCCCAGTGCAAACGCTCACCAACTCTTTAAAGGCTTCAGTTTTGTAGCCCCAGTCTCCCTGGAGGAAAGTAAAAGTGCGCCACTAGTCAACATTCTCCCCATAGTGCAGG[T/A]AAATCTCTCTCTTTTACTATGCATATGTGTGAATTATACATGTTTGGTGTTCTCTTTTTAAATTTAATGGTAAAAAAATCATGTAAAAGTTTAATGTAATGAAAATGTGTACAGTGGATCCAGAAAGTATTCATAGCGATTCACTATTTCCACGTTTGTTTATGTTACAGTCTTATTATAAAATGAATTAAATTAATTTATTTCCTTTAAAATTCTACACACAATACCCCATAATGACAATGAGAAAAAAAGATTTTTTGAAATTGTTGCAAATTTATTAAAATAAAAAAACCTGAAAAATCACATGTACATCAGTATTCATATAAGTAGATTTAAGAATATAAGTATTGCTCAATACTTTGTTTATGCATCTTTGGCAGCAATTCCAGCCTCAAGTATTTTTGAATATGATGCCACAAGCTTGGCGCACCTGTTATTGGTCATTTTTGCCCATTCCTTTTTGCAGTACCTCTCAAGCTCTATCAGGTTGAATGGGAAGC
Associated Phenotype:
Not determined