ZMP
pkz
Ensembl ID:
ZFIN IDs:
Description:
protein kinase containing Z-DNA binding domains [Source:RefSeq peptide;Acc:NP_001035466]
Human Orthologue:
EIF2AK2
Human Description:
eukaryotic translation initiation factor 2-alpha kinase 2 [Source:HGNC Symbol;Acc:9437]
Mouse Orthologue:
Eif2ak2
Mouse Description:
eukaryotic translation initiation factor 2-alpha kinase 2 Gene [Source:MGI Symbol;Acc:MGI:1353449]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa22387 | Essential Splice Site | Available for shipment | Available now |
| sa42307 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa42306 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa22386 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa22387
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000038391 | Essential Splice Site | 205 | 511 | 3 | 11 |
| ENSDART00000074230 | Essential Splice Site | 205 | 448 | 3 | 9 |
| ENSDART00000123580 | Essential Splice Site | 205 | 489 | 3 | 12 |
Genomic Location (Zv9):
Chromosome 13 (position 51174624)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 49885721 |
| GRCz11 | 13 | 50198964 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATAAGATTGATGACAAGATCTATGCTGTGAAGAGAGTCGAGTTCAACAGG[T/G]AAGTTCACATCATGAGATCATGACTCAACTTAGAATGAACACTCGTGTAT
Long Flanking Sequence:
AACTGACTTCAGTTTCAGGGTGAGTATACTTGACCAGACATGCCACATTAAAAATACTATTTTGGTAAATACTGTAGTGTTTTTTGAACCGAACCGTAGATAATACCATGATAGTCTGTAGTATACTTTAGTTTTACTACAGAAAACTGATGTATTGTGGTATAATATACTCATATTGGGCCATTTGTTTATATTACTACAGTTGTTGTGTTAATTATAAAATCACCACAACAGATTACTTCACTATATACAGTATGGTCTAAAAAACACTTGTGTTGTAGTATAGTATATTTCAGTTATTAAATCAATGTTTTGTTAACAGGGATGATGCATAATGTTACTGCCTATTGCTGTTTGACATGTATCTTCTGTTCTGCAGGATGTCTCAAACTTTTGATGTGATCGAAGAGCTTGGTGACGGAGGCTATGGTTTTGTTTGCAAAGTAAAACATAAGATTGATGACAAGATCTATGCTGTGAAGAGAGTCGAGTTCAACAGG[T/G]AAGTTCACATCATGAGATCATGACTCAACTTAGAATGAACACTCGTGTATTGAGGTAAAGTTGATTTTATGTTCGCACATTAATTTACTGAAACGCTCCCTCGAATTTTGAGTCTGAAATTGCATGTAGATCTGACTTCAAAACAACAATAGCACTATTTAATTGACTGTGGTGTGGACAATGTTGTACTTTGATAGTCATTGGCTGATAATAGGATTTTCCTGTTGAGAATTGGCAAATAGTCCTTTTCTGAACTTACATTTTTGAGGAGAAGGTCAGAATGTGCGAATATAGACCATTTCAATGTGGTCATGTCATAGGCACATCAACATTTCCTACTTGTTAACAAACTGTTTCATAACTTTAACAAGAGGTAATTCAATCATAACTTAACGTTAAAACAGCTATCATAGCATTATTTATCAACAGGAAATATGCTGAGGCCATTGCTTTTGTTTACATCCCTCAAAATGGTCTATAGAACCAACTTTACCCTTATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42307
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000038391 | Essential Splice Site | 246 | 511 | 4 | 11 |
| ENSDART00000074230 | Essential Splice Site | 246 | 448 | 4 | 9 |
| ENSDART00000123580 | Essential Splice Site | 246 | 489 | 4 | 12 |
Genomic Location (Zv9):
Chromosome 13 (position 51171859)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 49882956 |
| GRCz11 | 13 | 50196199 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTGATTCTGACAACTGGATGTCAAATCAAGAAACAAACGAAAAGTCAAA[G/T]TAAGCAAATCTTCAACACTGTAGACCGAAACACTCAGTTCTTCACTGTAA
Long Flanking Sequence:
CCTCATTTAGTGTTTACAGGAACACGATTATCTTTATAATGATATATATTGTGGTTATCTGTATATGAAATAACGAATAACAAATGTAGCAGGGCATTAAATTACTGTTTATTTCTTTGCATTTTAACTTTGTAAACTATAAAATCACGCGTCTTCTCACGGCTTGGGTCTCATTTTGTGAGCCGACTGACAACAGTTGTTCGCTCCTCTCCTTCTCCCCTGCTCTGCTGGCCACGCCCACTCCTGCCCTTTGCTCGCGGAGCTCCACGCCCATTATCATGCATCTTTTGAAAAAATTCTGAGGTGGACCTGAACTGAAAGTGGGGGGTGTCATGGCCCTTTAATGCATATATGTATGTTTTTTAATATTACAACAGTGAAGCTGAACCTGAGGTGAAGGCATTGGCTCGACTAGATCACCCAAACATAGTGCGCTACTTCACATGCTGGCCTGATTCTGACAACTGGATGTCAAATCAAGAAACAAACGAAAAGTCAAA[G/T]TAAGCAAATCTTCAACACTGTAGACCGAAACACTCAGTTCTTCACTGTAATGATGTTTCTGTGTTTTACTGTCAGCACAACAGGTTCTTCAACTGACACTGATGATACTAATGAGAGAAGCGCTAGTGATGATGATGTTGCTGATGATGAAGATGATGATGATGATGATGTCAGTGATGATGTCACGTTAGGAATGGAAAGTCTGACTTTTACAGAGTGTGTACAGCTCTCTTCATATGAAAACAGATGTTTATTTTGGAAAAGTTTCTGCCAAATGCATTACTGTAAATGTGTCTGTTTTCAGATCGACATCTGCTGCTAAAGCCAGTGGACAGTGTGATCCTACAAATCAGTGAGTTTGTTTGTTGCTAACTATTCGTTTATGACAGAATAGAACATCAAAATTAATTAAATTCATTCAAATATATTATTTTTATTTAATATTTTTTTTATTTATGAATGAATATATATGCAGCTTTACAAGATGTCTATTATGTTGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42306
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000038391 | Nonsense | 410 | 511 | 8 | 11 |
| ENSDART00000074230 | Nonsense | 347 | 448 | 6 | 9 |
| ENSDART00000123580 | Nonsense | 388 | 489 | 9 | 12 |
Genomic Location (Zv9):
Chromosome 13 (position 51168717)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 49879814 |
| GRCz11 | 13 | 50193057 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCAGTGGTGACCCTATAGAGCGGTCAAAGAGGAAGGGCACACCCACATA[T/A]ATGAGTCCTGAACAGGTGACATATTTAAACTTTTAGCTTTTTCACAAAGA
Long Flanking Sequence:
TATTAGACTAGATATTCATCAAGACACTAGTAATCAGCTTAAAGTGACATTCAACTAGGTTAATTAGGGTAAAGTTAGGGTAATTAGGCAAGTTATTGTATAACAGTGGTTTGTTCTGTAGATAATCCAAAACTAATATTGCTTAAGGGGGCTAATAATATTAATAATAGACCTTAAAATGGCTTTTAAAAAAGTTAAAACTGCTTTTATTCTAGCTGAAATAAAACAAACGAGACTTTCTCCAGAGGAAAAAATATTATAGGAAATACTGTGAAAATTTCCTCAATCTGTTCAACATCATATAGGAAATATTTTCTATCTGGTAGACTTTTGTGTTCGTAATAAGCATTGTTCTAATATTGTATGCTTTTATTTTAGCCTGATAACATATTGTTTAATGACGGCAAAGTGAAGATTGGAGATTTTGGGTTGGTGGCGGCTCAGAAGAATCCCAGTGGTGACCCTATAGAGCGGTCAAAGAGGAAGGGCACACCCACATA[T/A]ATGAGTCCTGAACAGGTGACATATTTAAACTTTTAGCTTTTTCACAAAGATTTTAACAGCATCATGCTTGTATCAGCACATTTTTATGAAGTTTTTATGAGTATTTACATGGGGTGACACTGTGGCTCAGTGGTTAGCACTGTGGCCTTACAGCAAGCAGGTCACTGGTTTAAGTCCCGGCTTGGTCAGTTGACATTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTGGCGTGGGTTTCCTCTCCTCTGGGTGCTCCGGTTTCCCCCACAGTCTAAATACATGCGCTATAGGAGAATTGGATAAGTTAAATTGACTGTAGTGTGTGTGTGTGTGTGTGTGTGTGTGAGAGAGAGAGAAAATGAGTCTGTATGGGTGTTTCCCAGTACTGGGTTGCAGTTGAAAGGGCATCCACTGCATAAAACATATGCTGGAATAATTGGTGATTCATTCTGTTGTGGCGACCCCTAGTACATAAGGGACCAAGCTGAAGGAAAATG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22386
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000038391 | Essential Splice Site | 449 | 511 | 9 | 11 |
| ENSDART00000074230 | Essential Splice Site | 386 | 448 | 7 | 9 |
| ENSDART00000123580 | Essential Splice Site | 427 | 489 | 10 | 12 |
Genomic Location (Zv9):
Chromosome 13 (position 51167785)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 49878882 |
| GRCz11 | 13 | 50192125 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGGTTTGAAATGCTGTGGAAAATATCTTCTGGGATGGAGAGAGCAGAGG[T/G]CAGTATTGTTTCATTTATAATGTCATTCATTCATTCATTCATTCATTTTC
Long Flanking Sequence:
TGGAATAATTGGTGATTCATTCTGTTGTGGCGACCCCTAGTACATAAGGGACCAAGCTGAAGGAAAATGAAAGAATTTTATATACAATCTATATACAAATGCCGGGTTCCACACAATCAATCTGTGTTAAGAGAACATGAAGGAATTAAGTTATTATTAACTTACTAGTTTTTACCAATTTAAATGGATTTAATGTAAAACAAGATAAGTTCTCCCCCCCAAAAAAACTCAAGAATTGTGTCGCTTCAGCTTATTTTAAATAAGTAGCTTTTTATAGATGTCATTTTTTGAGTGGATAAAAATGTTTAATTAAAATAAAACTGATATGAAATTAATCAAATAAATAATTTTAATGAATAAAGTAAATAAGTAGAATAAATGAAATCTTTTTTTGTAGGAAAATCTGAGGAATTACGATGAAAAGACAGACATTTTTCCCCTTGGACTGATGTGGTTTGAAATGCTGTGGAAAATATCTTCTGGGATGGAGAGAGCAGAGG[T/G]CAGTATTGTTTCATTTATAATGTCATTCATTCATTCATTCATTCATTTTCTTTTTGGCTTATACCCTTTATTAATCTGGGGTCGCCACAGCGGAATGAACCACCAACTTATCCAGCATATGTTCCACACAGCGGACGCCCTTTCAGCTGCAACCCATCACTGGGAAACATCCATACACACTCATACACTACAGACAATTTAGCCTACCCAATTCACCTGTACCACATGTCTTTGGACTGTGGGGGAAAAGCGGAGCACCCTTGTCTTCACAAGAACGCAAGTCCGTTCTCTGCATTCTTGGAGTTGAGAAACAGCCTATGTCTACATGCCTAAATCCATTGTTGCTGCCATGTGATTGGCTGATTAGAAATTTGCGTTAACAAGCAGTTGAAAAGGTTGATATATATATATATATATATATATATATAGATATATATATATATATATATATATATATATATATATATATATATAAAAACACATTTACCGGCCACTTTATT
Associated Phenotype:
Not determined