Busch Lab

ZMP

map3k4

Ensembl ID:
ENSDARG00000053303
ZFIN IDs:
ZDB-GENE-090313-125, ZDB-GENE-990603-4, ZDB-GENE-990603-4
Description:
Novel protein similar to H.sapiens MAP3K4, mitogen-activated protein kinase kinase kinase 4 (MAP3K4)
Human Orthologue:
MAP3K4
Human Description:
mitogen-activated protein kinase kinase kinase 4 [Source:HGNC Symbol;Acc:6856]
Mouse Orthologue:
Map3k4
Mouse Description:
mitogen-activated protein kinase kinase kinase 4 Gene [Source:MGI Symbol;Acc:MGI:1346875]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa1374 Nonsense Available for shipment Available now
sa11281 Nonsense Available for shipment Available now
sa22347 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa1374
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000075333 Nonsense 196 1488 3 30
ENSDART00000137256 Nonsense 230 770 3 8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 36226524)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 35699090
GRCz11 13 35824922
KASP Assay ID:
554-1286.1 (used for ordering genotyping assays)
KASP Sequence:
ACGCTCGCCGTAGTGTTAATGACCAGGACCTGTACCTGTTYACCGCTCGA[C/T]AACACATACCTGACATYATCAGCGAGGTTTTGCACTTCAAAGTGGACTAC
Long Flanking Sequence:
TTTCACCAACAGAGAAGTCGTGTTCATCCAGCCCCTTGTCTCAGCGTGAGCGTGAGGGAGCCAGATCAGCCGAACCTCCTGAAGAGCACAGCTACAAGCAGGAAAAGAAGCAGCGCTTCAACCAGCGATCCAGCGAGCGGGACGTCAAGAAGAAGTTTGAAGGCGCCTTTATGCTGGATCCTGTTTCCAAGTCCAGTACCATCGGCTCCAGAAACATGGATCCCCGCAAGCCCTACCTGAGTCTGGGCATGATCCCCGTTCGCACCCATCGGCAAACTTCGCGCACAGACTGTCCTGCAGACCGCCTTAAGTTCTTCGAGACCCTGCGGTTGCTGCTTAAACTCACCTCCATGTCATCCAAGAAGAAGGAGAAGGAGCAGCGAGGTCTGGAGAACACCGCTTATATGGAGCAGAACAACGAGGTCATCTGGCTGGAGCTGCAGGCCTGGCACGCTCGCCGTAGTGTTAATGACCAGGACCTGTACCTGTTCACCGCTCGA[C/T]AACACATACCTGACATCATCAGCGAGGTTTTGCACTTCAAAGTGGACTACAGTAGCCTGTGTGGACTCGAGAGTGGCGCCTCTGTTGAGGAGAGCAACTCCTGTCCTGGTGAAACTAATTGCATGGACGATCCATTTAGCTTTAGCACATGTTCCGCGTCCTGGCAGGAAATTGATGCCGCTGCTCCTTTTTCTTCAGGGCTGGAGTGCCGCAACCACCTGCAAAGGCAGCGAGTAGCTTTCGATCAGGTAAAACGGGTCATGTCGCTGTTAGAGTCGGTGGAGGCTTTGTACCCTTCTCTGCAAACCTTGCAGAAGGACTATGAGAAGTATGCAGCTCGGGACTTCCAGGGCAGGGTGCAGGCGCTCTGCTTATGGCTCAACATCACTCAGGACCTGAACCAGAAACTGCGCGTGATGGGCACCGTGCTGGGCCTCAGGGACCTTTCCCGCATCGGCTGGCCCATCTTTGAGATTCCATCACCTCGCTGCTCTCGAGGC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa11281
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000075333 Nonsense 599 1488 7 30
ENSDART00000137256 Nonsense 659 770 6 8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 36219921)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 35692487
GRCz11 13 35818319
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTTCACRCAGGTGTACTTTGACTACATGCGCAGCTGGATCCAGATGTTA[C/T]AGCAGCTTYCTCAAGCRTCCCACAGCCTGAAGAACCTGCTGGAGGAGGAA
Long Flanking Sequence:
TCACTAAACTGAACTTCAACTCTGAAAACTGGACTGACACAGTTTCAATATACTAGAACTTCCATGTTAAGCTGATTTAACACAATCTACATTGTAAAACACATAGAAATAAAGATGAATATTCAATTCATGAATATTCACAAATTATGACATTGCTTACTATAAGATTGTTACAGTGTATTTGTGACTCAGTGGGTGCTTTGTGTTTCACTGCCAAGATATTTTTATTTGCCCAGCTGTGTGCTTTTTAACGTTTAGTTTTTTTTTTTTTGCATGCGAGTAATTAGAGAAAATAACTTCTGATGAAATATTAGCGATCAAAGTTTTAAGCAAATCTGTAAAAATAAGATTTATACTTCAGCTGTAAAAGCAGTTGGACAAATCCCGGTATTTCTCCCTCACGAACAGCAGTGATCTGAATAGACAGACAGTAAATCTTCGGTGTGTCTGTGTTCACACAGGTGTACTTTGACTACATGCGCAGCTGGATCCAGATGTTA[C/T]AGCAGCTTCCTCAAGCATCCCACAGCCTGAAGAACCTGCTGGAGGAGGAATGGAACTTTACCAAAGTCATCACTCCATACATCCGAGGCGGAGAAGCCCAGTCTGGGAAGCTCTTCTGGTTGGTATTTTCAATCTGTGCGCTTGCTGTATAAAGGACAAATGACAAATAAATGTTGAAGTATTATACAATGTATTTGGTTTCTGTTCTACTAGAGGAATTACAGACATAAATTCAAAAAAAAAAAAAAAAAAAAACTGTTTAGAGTCAACATACTCCTTCATATAATAATTCACTATTTAAAATGGGACTTGACAGCAAGTAGCTAGAATGTATGAAGAAGATTTTTAGCTTGCCTATTGAGGAGAAACTTCACAAATTTGCTGCCCAAATATTTTTGTTGAAACTCATTTTTTTTTTTGTCTATTGTGTGTCTATGGGTATTTGGGCAATTTTGGGAATTTATTAAGGCAAGGATGTTCAAACTTGGTTCTGGAGGGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22347
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000075333 Nonsense 1224 1488 23 30
ENSDART00000137256 None None 770 None 8

The following transcripts of ENSDARG00000053303 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 36202868)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 35675544
GRCz11 13 35801376
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTACGATAACGTGATGCATGTGGGCCTGCGCAAAGTCACCTTTAAATGG[C/T]AGAGAGGAAACAAGATCGGTGAGTGAACAGCAGTGTGCATATGACGAAAC
Long Flanking Sequence:
ATAATTATCCAAAAATGTAATTGTCAAATAAATAAATATTTTAATTTGTAATAGTTTTACATTATTAATGCCTTGACTGTATTTTTGTTAAATTATTGCAGCCTTGCTATAAGCAGAAGATACTTTTAAATATTCCACATTATGAACTTTAAACTTTGACATGTTTTATAAAAAAAAATCATACTCAACCCTGAGACTGCAGTGACTAAACAGATGTTTCAATTGTTTTTAATGGATTCACATAAATGCACTGTTTTCTGAATCTGTTTTATTTATATTAAAATGTGCGTAATCTCTGAAATGGATCTTCTGCTCTTGTTTGTCCTGCAGACACAGCGCGTCAGAGCCCCCTGGAGGCAGTGCGGCGCTCCATACAAACCTTCGATGAGAAACACTATGCGCTTATGAGACAGAGAAACATCATTGGACAGGTTTGCAACACGCCGAAGTCCTACGATAACGTGATGCATGTGGGCCTGCGCAAAGTCACCTTTAAATGG[C/T]AGAGAGGAAACAAGATCGGTGAGTGAACAGCAGTGTGCATATGACGAAACGCCGCACAGGCTAGTTTCCTGAACACTGTTTCTGGCTGACAGGTGAAGGGCAGTATGGGAAGGTTTACACATGCATCAATGTGGACACTGGTGAACTAATGGCCATGAAGGAGGTATGTAAAGTATCAGCTATATAAACGTGTATAATTATTTATATTTTACAGTAACATTATTAATTTGTTATTAGCATTAGCTTAGCTAACACAAACCAGTAATGAGAATCTGGCATTTGTTAACCTTTTGTTAATGTTAGTAAATGAAAATGTTCAAATGTTGAGATTAATGTTAAGATAATCAATGCTACTGTCTAGAAGTATTGCCTACTGTTAGTTCTTGTTAATTAATTTGAACTGTAAATTGAAACCATTTTAGCTTTTTACACTTGAAGAGTTCAGATGCAGAAGCTGTTAAACGCCACTTCCGCCAAAAATGAGATAATGACATTGAGTA
Associated Phenotype:
Not determined