Busch Lab

ZMP

ercc6

Ensembl ID:
ENSDARG00000075612
ZFIN ID:
ZDB-GENE-070228-1
Description:
Novel protein similar to H.sapiens ERCC6, excision repair cross-complementing rodent repair deficien
Mouse Orthologue:
Ercc6
Mouse Description:
excision repair cross-complementing rodent repair deficiency, complementation group 6 Gene [Source:M

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa22329 Nonsense Available for shipment Available now
sa22330 Essential Splice Site Available for shipment Available now
sa1301 Nonsense Available for shipment Available now
sa35517 Nonsense Mutation detected in F1 DNA Not yet available
sa2690 Nonsense F2 line generated Not yet available
sa22331 Nonsense Available for shipment Available now
sa35518 Splice Site, Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa22329
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Nonsense 88 1390 1 19
ENSDART00000134027 Nonsense 88 204 2 4
ENSDART00000134809 None None 560 None 12
Genomic Location (Zv9):
Chromosome 13 (position 31098963)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30744911
GRCz11 13 30875361
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACCACAGCTCTCAGGCCGCTGAGCTCCAAGGTCTGGGTGTGGATGTTTA[C/A]GACCAAGATGTCCTGGAGCAGGGTGTGTTGCAGCAGGTGGACAGAGCCAT
Long Flanking Sequence:
AGTAAAATCTGAGACTGTTGTAATGTTAAATTGTGTATGTCTGTTTATTTGTTCTTTAACAGTCATTGTAATTGCTCAAAACACATTTTTACAATTAAAAATGTGATTCTTGAAAAAGCGACTCTTTTTAGTTATTCTTGATATAGGCTAAAATACTCTTACTTTGGTGTTCAGTTACTCAAATTTTACAACCAAACTTTACACTCTTAGACCATTCTAATTCACAGTGACATAGCAATGCCAGTAGAAGGTACCGAGGACCAGGCCCTGTCACCCCTGTCCAGCCCTGTGAGTGCTCTTACTCCTGGAGCTCCAGAAGACAATGGCCTTTCCATCCCTGGAAGTAGTAGGGAAGAGCCAGCGGCTGCCTGTCCGGAGACTGTCGGGGCACAGAATTCGAGAAAATCACAACCTCTGCTCCAGATCAACCGTCAGGAGATCCTATCGGTGGACCACAGCTCTCAGGCCGCTGAGCTCCAAGGTCTGGGTGTGGATGTTTA[C/A]GACCAAGATGTCCTGGAGCAGGGTGTGTTGCAGCAGGTGGACAGAGCCATTCAGGAAGCCAACCAGGCTGCGGCTAAAGCTGAGGCCCAGAAAGAATACGAGTCTGTACTGGATGACGTCAGGTGAATTTATGGCTGCCTTACTTGCTCTTGTAATATTGTGCAATATGTGTCAAAAAATGAATAGCTCAAATTTGAGGTTGATCTACAGTAATGTGGTTGGTTTGTAAAACATTTCAGGTCATGTACAAGTGCTTTGAAACACATCAACAAAATATTGGAGCAGTTAACCCCTCATGCTGCCTCTAGCAAGGATATCAGTCGGAAAATTGAGTCTGTTAAACGGCAAAAAGAGAATAAGGTGAGTATATGCTGGATTGTTAGTTTTGCTGGGTTTAGCCTGTACTGCTGCATTATATGAAATTCTAGTCGGAAATGCTGTCTTCATTTGATCAAAAATACATTATAAACGTTAAATTCATTTAGAAATGTTCATGCTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22330
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Essential Splice Site 129 1390 2 19
ENSDART00000134027 Essential Splice Site 129 204 3 4
ENSDART00000134809 None None 560 None 12
Genomic Location (Zv9):
Chromosome 13 (position 31099201)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30745149
GRCz11 13 30875599
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAAATTTGAGGTTGATCTACAGTAATGTGGTTGGTTTGTAAAACATTTC[A/T]GGTCATGTACAAGTGCTTTGAAACACATCAACAAAATATTGGAGCAGTTA
Long Flanking Sequence:
TGCCAGTAGAAGGTACCGAGGACCAGGCCCTGTCACCCCTGTCCAGCCCTGTGAGTGCTCTTACTCCTGGAGCTCCAGAAGACAATGGCCTTTCCATCCCTGGAAGTAGTAGGGAAGAGCCAGCGGCTGCCTGTCCGGAGACTGTCGGGGCACAGAATTCGAGAAAATCACAACCTCTGCTCCAGATCAACCGTCAGGAGATCCTATCGGTGGACCACAGCTCTCAGGCCGCTGAGCTCCAAGGTCTGGGTGTGGATGTTTACGACCAAGATGTCCTGGAGCAGGGTGTGTTGCAGCAGGTGGACAGAGCCATTCAGGAAGCCAACCAGGCTGCGGCTAAAGCTGAGGCCCAGAAAGAATACGAGTCTGTACTGGATGACGTCAGGTGAATTTATGGCTGCCTTACTTGCTCTTGTAATATTGTGCAATATGTGTCAAAAAATGAATAGCTCAAATTTGAGGTTGATCTACAGTAATGTGGTTGGTTTGTAAAACATTTC[A/T]GGTCATGTACAAGTGCTTTGAAACACATCAACAAAATATTGGAGCAGTTAACCCCTCATGCTGCCTCTAGCAAGGATATCAGTCGGAAAATTGAGTCTGTTAAACGGCAAAAAGAGAATAAGGTGAGTATATGCTGGATTGTTAGTTTTGCTGGGTTTAGCCTGTACTGCTGCATTATATGAAATTCTAGTCGGAAATGCTGTCTTCATTTGATCAAAAATACATTATAAACGTTAAATTCATTTAGAAATGTTCATGCTGTGTTTTTGTGGATTCCATACGATTTTTAAAAAGTATGTTTTGTTAAGTACTAGTTTTATTCATCAACAACACAATAATTAAATTGACAGTAAAATCTTGTTAAATCATATTAAAAAATATTTCTATTTCAAATAAATGCTTTTATTAGTTGCATGTATTTTCCCCCACAAAAATATAAAGCAGAAAAAAAAATTCAACATTGATTATAAAAAGAACCCTCATTAATAGTAATTTTTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1301
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Nonsense 180 1390 3 19
ENSDART00000134027 Nonsense 179 204 4 4
ENSDART00000134809 None None 560 None 12
Genomic Location (Zv9):
Chromosome 13 (position 31100139)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30746087
GRCz11 13 30876537
KASP Assay ID:
554-1216.1 (used for ordering genotyping assays)
KASP Sequence:
AGCCTGTTATCCTTTTACAGGAGAAGCAGTTAAAAAAGATCAGAGCCAAG[C/T]AGAAGAGATTGCAAGCTCTTCTTGACGGAGAGGATATACAGAAGCTTGAG
Long Flanking Sequence:
AAAGCAGAAAAAAAAATTCAACATTGATTATAAAAAGAACCCTCATTAATAGTAATTTTTGAAATATTTAATGATTTAACACCAATTAAAATAGATTATGACAGCAATTCAGTATTTTAAAAATATTTCTGAAGGTCCATGTGATGCTGAAGACTGCAATAATGATCATGTAAATTCAGCTTGAAATCACAGGAATAAATTATATTTTAAATCTATTCATACTCATTTAAAAATGTAATAGCTCACAGTTTTACTGATTTACAAATAAATTAGGCTTTGTTAAGGAGAAGATAATTACTTTAAAGCAAATAATGTTTGACTTTTAGTATCTATAATTGGTTTGTATTATTTTAAAAATATATATTTGAACTTTATTTTCTATTGAAATAAGAGCATGCTATATTTCAGTGATGCATTGCATAAAAAGATCTTAGCACACAATACTTAAAAAGCCTGTTATCCTTTTACAGGAGAAGCAGTTAAAAAAGATCAGAGCCAAG[C/T]AGAAGAGATTGCAAGCTCTTCTTGACGGAGAGGATATACAGAAGCTTGAGGCAGAATTATTGATTGAGGATGACGAGGGTAAGTATGAAGCGCAGGCCTTTACATGATTTGTATTATCATCATATGCTTTTTTAATCTTGCTCAGCAATCACTTTGTGTATATGGGCACCTTAAATTATACATTTAGAGAATAGTTATATCATAGAAAGTGTAAATCAGTTCATTTATCTTGTTGTTTTATGTTTGCTTTGTAGTTTATAGTATGTATACAACCGAGTTCTTTAGACCATTTTGGGGGATGTAAACAAAAACAATGGTCCCAATGTATTTCCTGTTTTACATATGTAATTTCTATAGCTTTCAAAAATACAAAAAGAGCTACATATTGATAAATAATGTTATGATAGCTGATTTAACATTAAGTTATGATTGAATTGCCTCTGGTTACAGTTATGAAATAGTTTGATAACAAGCAGGAAATGTTCATGACCAATGACATC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa35517
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Nonsense 193 1390 3 19
ENSDART00000134027 Nonsense 192 204 4 4
ENSDART00000134809 None None 560 None 12
Genomic Location (Zv9):
Chromosome 13 (position 31100178)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30746126
GRCz11 13 30876576
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGAGCCAAGCAGAAGAGATTGCAAGCTCTTCTTGACGGAGAGGATATA[C/T]AGAAGCTTGAGGCAGAATTATTGATTGAGGATGACGAGGGTAAGTATGAA
Long Flanking Sequence:
CCCTCATTAATAGTAATTTTTGAAATATTTAATGATTTAACACCAATTAAAATAGATTATGACAGCAATTCAGTATTTTAAAAATATTTCTGAAGGTCCATGTGATGCTGAAGACTGCAATAATGATCATGTAAATTCAGCTTGAAATCACAGGAATAAATTATATTTTAAATCTATTCATACTCATTTAAAAATGTAATAGCTCACAGTTTTACTGATTTACAAATAAATTAGGCTTTGTTAAGGAGAAGATAATTACTTTAAAGCAAATAATGTTTGACTTTTAGTATCTATAATTGGTTTGTATTATTTTAAAAATATATATTTGAACTTTATTTTCTATTGAAATAAGAGCATGCTATATTTCAGTGATGCATTGCATAAAAAGATCTTAGCACACAATACTTAAAAAGCCTGTTATCCTTTTACAGGAGAAGCAGTTAAAAAAGATCAGAGCCAAGCAGAAGAGATTGCAAGCTCTTCTTGACGGAGAGGATATA[C/T]AGAAGCTTGAGGCAGAATTATTGATTGAGGATGACGAGGGTAAGTATGAAGCGCAGGCCTTTACATGATTTGTATTATCATCATATGCTTTTTTAATCTTGCTCAGCAATCACTTTGTGTATATGGGCACCTTAAATTATACATTTAGAGAATAGTTATATCATAGAAAGTGTAAATCAGTTCATTTATCTTGTTGTTTTATGTTTGCTTTGTAGTTTATAGTATGTATACAACCGAGTTCTTTAGACCATTTTGGGGGATGTAAACAAAAACAATGGTCCCAATGTATTTCCTGTTTTACATATGTAATTTCTATAGCTTTCAAAAATACAAAAAGAGCTACATATTGATAAATAATGTTATGATAGCTGATTTAACATTAAGTTATGATTGAATTGCCTCTGGTTACAGTTATGAAATAGTTTGATAACAAGCAGGAAATGTTCATGACCAATGACATCACAACATTGAAATGGTATTTAAGTATGCTTCCAATATGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2690
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Nonsense 496 1390 6 19
ENSDART00000134027 None None 204 None 4
ENSDART00000134809 Nonsense 55 560 2 12
Genomic Location (Zv9):
Chromosome 13 (position 31107314)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30753262
GRCz11 13 30883712
KASP Assay ID:
554-2791.1 (used for ordering genotyping assays)
KASP Sequence:
CCTTTGCTTTTGTTGTCCAGGTATCAACAGACAGGTGTCAGGTGGATGTG[G/A]GAACTGCACTGCCAGCAAGCAGGAGGCATTCTGGGAGACGAGATGGGCCT
Long Flanking Sequence:
GAGAAAAAGAGGCAAAGAGAGAAGCAGGCGAGGAGGAATCCGACGAGAGCGATGCAGAGTTTGATGAAGGATTTAAAATACCTGGTTTCCTCTGGAAGAAGCTCTTCAAGTATGGCTCGCATAAATCACACATACTCTTATATTAAAAGAAAGGAATCGATCATGATAAGTCATGTTGTTTTTGCAAATGCAATGTGAAATATTAAATGTGTGCGCAAATTACTTACAATTTAACTTTAACGAGTCCCGAAAGGAGGAGGGATGATGTCTTTTAGGCCTAGAAAGTAGGACTGTGCTGCGGTGTTCTGGATGTGTTTTACAGCACATCAATTGGGCAACACTTATGGCCCATTTATCCGGAATCAATAGTGATAATGGCTCTATGATTAATTCATCAGCCGCTGTGTTTGTGTTTGTGTTTGTGCTGGAGCTGCGCTTTGTGTGACAAAACCTTTGCTTTTGTTGTCCAGGTATCAACAGACAGGTGTCAGGTGGATGTG[G/A]GAACTGCACTGCCAGCAAGCAGGAGGCATTCTGGGAGACGAGATGGGCCTGGGCAAGACCATCCAGATAATTGCTTTCCTGGCAGGCCTGAGCTACAGCAAGCTGAAAACACGTGGCTCCAATTACAGGCAAGGGACCCTACATGCTTGTACAGTTTCATATCTACTGTATGATAGGAAATCGAATTCTGTCTCAGAGTAAGATTTAAATTTATATATAAAAGGTTAACTATTCACAGTTTCTCTGAATTTCACTTGCCGTTGGTTTGAGCAAATTAATAATATTGGTTTATTCCATAAAGGTTTGATTAAATTTAATATGATTTCCATATATATATATATATATAAATATCCTCTAGGATTTTTTCCAGCTGTGGCGGCAGACTCTGTTGGCCATTTTACACAGATCTATCACTACATGTGGCGTTATTTCATTGACAAATGTCATGGGCGCAGATTGCATTCATGTAATAGCCTATGTCAATCTCTGCTTGAGCGACG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22331
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Nonsense 619 1390 8 19
ENSDART00000134027 None None 204 None 4
ENSDART00000134809 Nonsense 178 560 4 12
Genomic Location (Zv9):
Chromosome 13 (position 31116210)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30762158
GRCz11 13 30892608
KASP Assay ID:
2260-6564.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATACATACGCATTATGCAAGATTACATCCAGAGATACGACTGGCATTA[T/A]GTCATCCTGGATGAGGGCCACAAGATAAGGAACCCAAATGCTGGGGTCAC
Long Flanking Sequence:
GGCAACCCGGGGTGCTGAAATATAATTGGCTAGATTGGCAGTGGACGGGTAAAGAACCAAAACAAAGACAGCATTTCGGCACGGAAAACACATTTTCAAAGCGGAAAAACTTAAGCATTGATTTTCAGAAGAATGATCACTTGGCATGTTTCTTAAATTTCTGAAAACATATTATGGTATTTTTATGCTTTAGAAGAGTGAAAAACTTAGATGCAGCACCTTTAACAAAAATAAATTAAAACAAGACCAGTGTAGAAGGTTTGCACCCTAAAGTTGTAAATATGAATGAATCTGTTTTTGAAAAAATGGAGTAAGTCAATAATTTATCGATCCATTCATAAAGTCACTTTTGAGTTGTACGAATGTTTTAATTCACTTTGTTTTCCTTATTATCAGGAGAAGCTCATTCCAGAAATTGTGGCCAGTCACGGCATCCTCATCACCTCCTACTCATACATACGCATTATGCAAGATTACATCCAGAGATACGACTGGCATTA[T/A]GTCATCCTGGATGAGGGCCACAAGATAAGGAACCCAAATGCTGGGGTCACTACAGCATGCAAGCAGGTGATCATTTCTTTTCCTTCTATTCTTTTTTTACTCTGTAAAAAGCAGTTATTTACTTAAAAGTGGCTTGCCTTAAAATGTACAAGTTTTTTTTGCTTGAGGACGTGAATACACCTGTTTTAAACTTAAGTTGACTAAACTTAATTTTTATAATTATGCACACTTCTTTTCCGTAATAATTTTTAAACTTGGCGGCATGGTGGCTCAGTGGTTAGCCCTGTCGTCTCACAGCTAGAAGGCTACTGGTTTAAGTCCAAGGTGACATTTCTGTGTGGAGTTTTCATGTTCTCCCCGTGTTCACGTGGGTTCCTCCGGGTGCTCCGGTTTCTCCCACTGTCCAAAGATTTGTAAACAAAAAAATTGGCCATACTGTATGTGTGTGTGTGAATGTAAGTAAGTAAGGGTGTGTCCAATAATGGGTTGGGGCTGGAAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35518
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112380 Splice Site, Nonsense 641 1390 8 19
ENSDART00000134027 None None 204 None 4
ENSDART00000134809 Splice Site, Nonsense 200 560 4 12
Genomic Location (Zv9):
Chromosome 13 (position 31116274)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 30762222
GRCz11 13 30892672
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGGCCACAAGATAAGGAACCCAAATGCTGGGGTCACTACAGCATGCAAG[C/T]AGGTGATCATTTCTTTTCCTTCTATTCTTTTTTTACTCTGTAAAAAGCAG
Long Flanking Sequence:
AAGACAGCATTTCGGCACGGAAAACACATTTTCAAAGCGGAAAAACTTAAGCATTGATTTTCAGAAGAATGATCACTTGGCATGTTTCTTAAATTTCTGAAAACATATTATGGTATTTTTATGCTTTAGAAGAGTGAAAAACTTAGATGCAGCACCTTTAACAAAAATAAATTAAAACAAGACCAGTGTAGAAGGTTTGCACCCTAAAGTTGTAAATATGAATGAATCTGTTTTTGAAAAAATGGAGTAAGTCAATAATTTATCGATCCATTCATAAAGTCACTTTTGAGTTGTACGAATGTTTTAATTCACTTTGTTTTCCTTATTATCAGGAGAAGCTCATTCCAGAAATTGTGGCCAGTCACGGCATCCTCATCACCTCCTACTCATACATACGCATTATGCAAGATTACATCCAGAGATACGACTGGCATTATGTCATCCTGGATGAGGGCCACAAGATAAGGAACCCAAATGCTGGGGTCACTACAGCATGCAAG[C/T]AGGTGATCATTTCTTTTCCTTCTATTCTTTTTTTACTCTGTAAAAAGCAGTTATTTACTTAAAAGTGGCTTGCCTTAAAATGTACAAGTTTTTTTTGCTTGAGGACGTGAATACACCTGTTTTAAACTTAAGTTGACTAAACTTAATTTTTATAATTATGCACACTTCTTTTCCGTAATAATTTTTAAACTTGGCGGCATGGTGGCTCAGTGGTTAGCCCTGTCGTCTCACAGCTAGAAGGCTACTGGTTTAAGTCCAAGGTGACATTTCTGTGTGGAGTTTTCATGTTCTCCCCGTGTTCACGTGGGTTCCTCCGGGTGCTCCGGTTTCTCCCACTGTCCAAAGATTTGTAAACAAAAAAATTGGCCATACTGTATGTGTGTGTGTGAATGTAAGTAAGTAAGGGTGTGTCCAATAATGGGTTGGGGCTGGAAGGGCACCAGCTGCATAAAACATATGCTAGAATAGTTGGTGGTTCACTCTGTTGTGGCAACCCTTGA
Associated Phenotype:
Not determined