ZMP
dgcr8
Ensembl ID:
ZFIN ID:
Description:
microprocessor complex subunit DGCR8 [Source:RefSeq peptide;Acc:NP_001116221]
Human Orthologue:
DGCR8
Human Description:
DiGeorge syndrome critical region gene 8 [Source:HGNC Symbol;Acc:2847]
Mouse Orthologue:
Dgcr8
Mouse Description:
DiGeorge syndrome critical region gene 8 Gene [Source:MGI Symbol;Acc:MGI:2151114]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa223 | Nonsense | F2 line generated | Not yet available |
| sa40420 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa223
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000051554 | Nonsense | 352 | 765 | 4 | 14 |
| ENSDART00000124915 | Nonsense | 352 | 782 | 4 | 13 |
| ENSDART00000144560 | Nonsense | 352 | 782 | 5 | 14 |
Genomic Location (Zv9):
Chromosome 5 (position 26193854)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 24021119 |
| GRCz11 | 5 | 24524919 |
KASP Assay ID:
554-0125.1 (used for ordering genotyping assays)
KASP Sequence:
ACCCACCAACCAGTAGCATTCCCTGCCTGCACTACAAGAAAATGAAGGAA[C/T]AAGAAGAAAGGGAACAGAATGGAGAGGTGACTCCGACAGCGGAGATTTCT
Long Flanking Sequence:
GACTCGAGAGGAGTATTTTTTTATTTGGTAGAAAATGCATTTTTAGAATTTTTATTTTTTATATCTACAACTTTTATTGCTTTTAGTTTGACAATAGCACAAAAACCGAAACCCTAAATTGGATTCTTGCTGGCTATACTTTTAGTAATTGTTAAATATAATTATTTTTTTATTTGATTTTTAAGGTCGTGGTCGACCGCCAACTGAGCCATTACCTGATGGGTGGATCATGACATTCCATAACTCCGGCATTCCAGTCTACCTCCACCGGGAAACCAGAGTTGTAACCTGGTCTAGACCTTACTTCCTTGGAACAGGAAGCATTAGGGTAAACATTTTGACTTGCCTAAGATATGACACTTACTGTAAATTGCAATTAAACAATTACAATGTTCAATTTATTTTTTCACGCTCCTCATCTCTATTCTCTTATTTTCCCCTAGAAACATGACCCACCAACCAGTAGCATTCCCTGCCTGCACTACAAGAAAATGAAGGAA[C/T]AAGAAGAAAGGGAACAGAATGGAGAGGTGACTCCGACAGCGGAGATTTCTCCAGTCAAATCTGGGGAGGAGGGTATCTCACTGGAGCGAGCCGATGAGCCTGACTCCACTGCCACTGAAGAGCCCACCGGCAGACCAACATCAGAAGATCCGGATCTTGACCTCATGGAGCCAGGAGGGTCTTCTATAGAGGGGAAGGATGGCCAAACCGGGGATACTGCACAGGGAGCATTGGGCCAGGTCAAAGCCAAGGTGGAGGTCTGCAAAGATGAGTCTATTGGTAAGTGGACTTTATACTTATAATTTTTTTATATATACAATAATCAAAATTTGCAGAGGATTAAAGCCTTTTAAAGTTTTCATAAAATTATTTAACAGCCATTTTTGGTCTTGGGACAATTTTGAAAAGCTATTTTCCCCCCACTTCAGATGTTGATTACTGTATACATCACTGTGAAAATGTGCCTGGCATGTAAACCTCCTCTTGTGTTTTGTATCCCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40420
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000051554 | Essential Splice Site | 561 | 765 | 8 | 14 |
| ENSDART00000124915 | Essential Splice Site | 578 | 782 | 7 | 13 |
| ENSDART00000144560 | Essential Splice Site | 578 | 782 | 8 | 14 |
Genomic Location (Zv9):
Chromosome 5 (position 26195479)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 24022744 |
| GRCz11 | 5 | 24526544 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACGGCACTGGAACAGCTAGTAGTAAAAAACTTGCCAAGAATAAAGCTGG[T/A]ATCTTTTCCCCGTTTCTGTTTGAGTCCTGTAATCTCAGCAAGAAATCATT
Long Flanking Sequence:
ATTCAGAAGTGTAATTGCAATGTTACTCTGCAATGCGCTAATATTTAGCCCCAGGCTTTTAAACTATTTTTGTTGGGGGAAAATACAATATTGTGTCTGTAGCTTGCCCTATAAAAAGTAAAGTGTAAAGTCCTGATTTTCTGGAAAACCACTACTCTGTGCCATTACATATGTTTTTTTTTATTAATTAATTTTTTTTTAAAGTGAGCAACAAACCCATAAATAATGCATATGCCATCCCTAGAGTTAATCTTTTAAGAAACCAAATTACTTGTGGGCCATGTCTGTATAAAATGTCTCTTAAATCTACTGTAATGCATGTGTTTTTTGTTTTATATATACAATGTTTTTGTATATACTGTACTTAAATGTAAAGTCTCCATATTTTTTTTTCCCTCAGAAAACCCAAGTGAACCCTTCGGAGCCTCAGTGATTATAGACGGTGTTACATACGGCACTGGAACAGCTAGTAGTAAAAAACTTGCCAAGAATAAAGCTGG[T/A]ATCTTTTCCCCGTTTCTGTTTGAGTCCTGTAATCTCAGCAAGAAATCATTTTGCTTCAACATAACTGCAAGCAAATAATTTACTTTATTCTCTTTTGTTTAAGCTCGAGCAACACTGGAAATCCTCATTCCTGACTTTGTGAAGCAGACGTCTGAGGAGAAGCCCGTAGAGGGAGATGAACTGGAGGTGCTGCTCTTCTTTATATTTTATCTTTGAGTAGATTAATTTATTTCATGGTACTTATGGTGTGTGTTGTTTTCCATTTCCACAGTATTTTAATCATATCAGTATTGAAGATTCAAGGGTGTATGAGCTGACCAACAAAGCAGGTTTACTCTCACCATATCAGATCCTTCATGAGTGCCTTAAGAGGTGCGTTATCATTATGCATAATCAGTCATTTGATCACACTGACAATTCATTCTCACAGAAGATAGGTTTGTTAATACATCACAAACATCTGTGGGTCCTTGAAGTTTCATGTCTGAAAAGCAACTAAA
Associated Phenotype:
Not determined