Busch Lab

ZMP

mark3

Ensembl ID:
ENSDARG00000019345
ZFIN ID:
ZDB-GENE-030131-6232
Description:
MAP/microtubule affinity-regulating kinase 3 [Source:RefSeq peptide;Acc:NP_956179]
Human Orthologue:
MARK3
Human Description:
MAP/microtubule affinity-regulating kinase 3 [Source:HGNC Symbol;Acc:6897]
Mouse Orthologue:
Mark3
Mouse Description:
MAP/microtubule affinity-regulating kinase 3 Gene [Source:MGI Symbol;Acc:MGI:1341865]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa11075 Essential Splice Site Available for shipment Available now
sa22253 Essential Splice Site Available for shipment Available now
sa42167 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa31914 Nonsense Available for shipment Available now
sa9017 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa11075
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000013525 Essential Splice Site 260 722 8 16
ENSDART00000041293 Essential Splice Site 260 746 8 18
ENSDART00000087194 Essential Splice Site 260 503 8 13
ENSDART00000133342 None None 169 None 3
ENSDART00000134240 None None 195 None 6
ENSDART00000134972 None None 161 None 4
ENSDART00000138991 None None 177 None 3

The following transcripts of ENSDARG00000019345 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 15588100)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 15503133
GRCz11 13 15634125
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTACACACTGGTCAGCGGCTCTCTACCTTTCGATGGACAGAATCTCAAGG[T/C]TTCACCCTCTTTTMTCAATGTATTTTTTTGTGTGAGTTTGTKTATGTCAC
Long Flanking Sequence:
GTATTGTCACCAAAAACGCATTGTGCACCGAGACTTGAAGGTAAGCAGTTCTTGCTCTTAATTTTTAACATGAACAATAAAAAAACAGAACACTGTTTTATTATATTCAAGTGGGCACTTAAACCATAATTTAAAGCAATATTTTGTTAGATAATTTTTTTTTTCAGAAAACCATTTCACTTAATTTCTTAGATTACTTAATTACTCAACTTTTTATTTCTTAGGTTTTAAAATATATTTTCTTTTACCCATGTTTTCTCAGGCTGAAAACCTGCTGCTAGATGGTGATATGAACATTAAGATTGCTGACTTTGGCTTCAGTAATGAATTTATGGTGGGCAGTAAGCTGGACACGTTCTGTGGAAGCCCACCTTATGCTGCTCCTGAGCTCTTTCAGGGAAAGAAGTACGACGGGCCAGAGGTGGACGTGTGGAGCCTTGGGGTCATACTTTACACACTGGTCAGCGGCTCTCTACCTTTCGATGGACAGAATCTCAAGG[T/C]TTCACCCTCTTTTATCAATGTATTTTTTTGTGTGAGTTTGTTTATGTCACTGCATACTTACTGCTGTGTCTATTCTACAGGAATTGCGCGAACGTGTGTTGCGTGGTAAATATAGGATTCCTTTTTACATGTCCACTGACTGTGAGAATCTTCTCAAGAGGTTTCTGGTCTTAAACCCGGCTAAGAGAGGAACATTAGAGGTTTGTTATTTAGTCCATCTGTCATTCTTTCATATGCTGTCATATGCTGTGTAATTCCACAATCAGAACAGTTTTTTGTAATGCCTGTTTTGGTCAATGTTGCTCTGATAGTTGTGTAAATTGCTTCCTCACTTTGTCACTTTGGATAAAACTGTCTGCTAAATGACTAAATGTTAATGTAAATACAATATTGAACATTTGATAATTAATACCAGTATGAATTTCAGCAGCACTTTTTAATAACTCTTGACATTCTGCACTGAAAATGTAGTTTTTTTCATGAAATGTTTGTGAAAGTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22253
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000013525 Essential Splice Site 334 722 10 16
ENSDART00000041293 Essential Splice Site 334 746 10 18
ENSDART00000087194 Essential Splice Site 334 503 10 13
ENSDART00000133342 None None 169 None 3
ENSDART00000134240 None None 195 None 6
ENSDART00000134972 None None 161 None 4
ENSDART00000138991 None None 177 None 3
ENSDART00000013525 Essential Splice Site 334 722 10 16
ENSDART00000041293 Essential Splice Site 334 746 10 18
ENSDART00000087194 Essential Splice Site 334 503 10 13
ENSDART00000133342 None None 169 None 3
ENSDART00000134240 None None 195 None 6
ENSDART00000134972 None None 161 None 4
ENSDART00000138991 None None 177 None 3

The following transcripts of ENSDARG00000019345 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 15589012)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 15504045
GRCz11 13 15635037
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACCCTTCACTGAGCCAGATGCTGACATATCTGACCAGAAGAGAATTGG[T/A]AAGAGGAAATTAAGCAGCACTTCTTATTCATGCAGAAAAGAGAAAGAGTA
Long Flanking Sequence:
CCAGTATGAATTTCAGCAGCACTTTTTAATAACTCTTGACATTCTGCACTGAAAATGTAGTTTTTTTCATGAAATGTTTGTGAAAGTATGTGTTGGCAAATACTGTTATATTGATGCATACAAGTGAGATTTATTAAATAATTGTATTTGTTATACGTAACGTTTTAAACTATCTTAAACTGTATATATTTTTGTACTTTTTCTATAATTTAAATATAAACAATTACTCAAATATAAACACTTGTTTATGAGTAATTTGTTGTTTCTTTAGTAATAAAGCATACATATAATTAATCAAAAGTGATTAACCATTGAAAAAGTGCTGTCATGAATTTTCCCCTAGGCATTGAAAAGCCATTCTCGTTCTAAACTTGATTGTTTCTGAACTCTCTCCTTCAGCAAATCATGAAAGAACGCTGGATCAACTCTGGGTTTGAGGATGACGAGCTCAAACCCTTCACTGAGCCAGATGCTGACATATCTGACCAGAAGAGAATTGG[T/C]AAGAGGAAATTAAGCAGCACTTCTTATTCATGCAGAAAAGAGAAAGAGTATGTTTAAGACAAAGTTATTAATATTTCCCAAGTGTGTTCGTAAATTTTCAGCTCAAAATGTCTATCAGATAATTTATTATATCCGGCTGAATATGGGAATTTTGAGGTCGAGGAAACGGTTGCTGTATTTGTAGCCTGTGCTTTTAAATTTAAATTCAATTCAATTGATCTTTATTTCTTTAGTGCTTTTACGATATAGATTGTGTCAAAGCAACACAACGTAGAAGTTCTAATAAATTGCATTTGAAACTGTCAGTCCAGTTTTCAGAGTTCAAGTTCAATTCAGTTCAGTTTAGTATGGTTTAGTTTTCACTGCTAAATGTCCAACCACTGAAGAGCAGATCCATCAATGTGCAGCTTCACAAGTCCCAAATCAAGCAAGCCAGTGGGGACCAATGGACATCACCTTTTGACGAAAATGAGAAGAAAAAAAAGCTAGAGAGAAACCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42167
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000013525 Essential Splice Site 334 722 10 16
ENSDART00000041293 Essential Splice Site 334 746 10 18
ENSDART00000087194 Essential Splice Site 334 503 10 13
ENSDART00000133342 None None 169 None 3
ENSDART00000134240 None None 195 None 6
ENSDART00000134972 None None 161 None 4
ENSDART00000138991 None None 177 None 3
ENSDART00000013525 Essential Splice Site 334 722 10 16
ENSDART00000041293 Essential Splice Site 334 746 10 18
ENSDART00000087194 Essential Splice Site 334 503 10 13
ENSDART00000133342 None None 169 None 3
ENSDART00000134240 None None 195 None 6
ENSDART00000134972 None None 161 None 4
ENSDART00000138991 None None 177 None 3

The following transcripts of ENSDARG00000019345 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 15589012)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 15504045
GRCz11 13 15635037
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACCCTTCACTGAGCCAGATGCTGACATATCTGACCAGAAGAGAATTGG[T/A]AAGAGGAAATTAAGCAGCACTTCTTATTCATGCAGAAAAGAGAAAGAGTA
Long Flanking Sequence:
CCAGTATGAATTTCAGCAGCACTTTTTAATAACTCTTGACATTCTGCACTGAAAATGTAGTTTTTTTCATGAAATGTTTGTGAAAGTATGTGTTGGCAAATACTGTTATATTGATGCATACAAGTGAGATTTATTAAATAATTGTATTTGTTATACGTAACGTTTTAAACTATCTTAAACTGTATATATTTTTGTACTTTTTCTATAATTTAAATATAAACAATTACTCAAATATAAACACTTGTTTATGAGTAATTTGTTGTTTCTTTAGTAATAAAGCATACATATAATTAATCAAAAGTGATTAACCATTGAAAAAGTGCTGTCATGAATTTTCCCCTAGGCATTGAAAAGCCATTCTCGTTCTAAACTTGATTGTTTCTGAACTCTCTCCTTCAGCAAATCATGAAAGAACGCTGGATCAACTCTGGGTTTGAGGATGACGAGCTCAAACCCTTCACTGAGCCAGATGCTGACATATCTGACCAGAAGAGAATTGG[T/A]AAGAGGAAATTAAGCAGCACTTCTTATTCATGCAGAAAAGAGAAAGAGTATGTTTAAGACAAAGTTATTAATATTTCCCAAGTGTGTTCGTAAATTTTCAGCTCAAAATGTCTATCAGATAATTTATTATATCCGGCTGAATATGGGAATTTTGAGGTCGAGGAAACGGTTGCTGTATTTGTAGCCTGTGCTTTTAAATTTAAATTCAATTCAATTGATCTTTATTTCTTTAGTGCTTTTACGATATAGATTGTGTCAAAGCAACACAACGTAGAAGTTCTAATAAATTGCATTTGAAACTGTCAGTCCAGTTTTCAGAGTTCAAGTTCAATTCAGTTCAGTTTAGTATGGTTTAGTTTTCACTGCTAAATGTCCAACCACTGAAGAGCAGATCCATCAATGTGCAGCTTCACAAGTCCCAAATCAAGCAAGCCAGTGGGGACCAATGGACATCACCTTTTGACGAAAATGAGAAGAAAAAAAAGCTAGAGAGAAACCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31914
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000013525 Nonsense 421 722 12 16
ENSDART00000041293 Nonsense 421 746 12 18
ENSDART00000087194 Nonsense 421 503 12 13
ENSDART00000133342 None None 169 None 3
ENSDART00000134240 None None 195 None 6
ENSDART00000134972 None None 161 None 4
ENSDART00000138991 None None 177 None 3

The following transcripts of ENSDARG00000019345 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 15601441)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 15516474
GRCz11 13 15647466
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGAAGCATCTCCTCTAGTGAATCTCGAAAATCCAGACGCCATAGTGAA[C/T]AAGGTGACTTTCTCTTTGCATGCAGAAAAAAAATGTTGGCCCATTTTGGG
Long Flanking Sequence:
ATGTATGTGTGTAAAATATTTTTAACCCAATAAAGATGTTGAATTGCTTGCATGAATGAGTACTGATAGCTCAAATATAAGGTTATTGTATCAAGATTTAAAATGAATGGAGACTAATAACATTGGTCTGTATTCTTTTTATGTGTTGTTCTCCACAGATGTGATAGTGGGCATGGGCTTCTCCAAAGAGAAGATTCATGAGTCTTTGTTCAAAATGAACTATGATGAGGTCACAGCCATATACTTACTGCTGGGCAGGAAGACCCATGAGGTGAGTTACAAATGGCAATTGGTTACTTATAACAGGTCTGTTGTCCATAATAGTGTGAGCTGCTGTTTTTGTGTGTTTGTAGGAGGTCAGTGACTCCAGCTCCAATAGTAATCTCTCTGTGGCAAAGACCAGACCCTCTAGTGAGATGAACAGCCAATCACCATCTCACCTAAAGGTCCAGAGAAGCATCTCCTCTAGTGAATCTCGAAAATCCAGACGCCATAGTGAA[C/T]AAGGTGACTTTCTCTTTGCATGCAGAAAAAAAATGTTGGCCCATTTTGGGACAGGCTTTCAATTGAAAAAAATTCCTGTGAGCTAATTAGTTAATCAGCCAGTGAAACATTTGTTATCAGTATATTTTTTATGAAGGTTGCAATTATTTGAAACCATAAAATTGTGAAATATGTGCTTAATTTTCATCAGTGCTTAATTTTCTTAGTCTAACTGCTGCTAAAAATAATTTATTGTTATAATATGTGTAAAACAGTGTTTACATATAAACAGTGTAAAACTTGAAGTAATCTCAGCATTCAATGAAGGACGGCAGTATACATCTTGTGAGGGTTATTTTAAACAAAGCAAATGCTTGTTTGTTTGGATTAATCTTCTGCTTGTCAGGTGAATCATTTCATCAGTCATCTAAGCCAAAGGTTTTTGCATAGAAATGTTTGCATTTGTAGATTACTAGTCTTCAAGTATTAATTCTTATGTCAAAGTGTTTTGCATTTTTAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9017
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000013525 Nonsense 612 722 16 16
ENSDART00000041293 Nonsense 636 746 18 18
ENSDART00000087194 None None 503 None 13
ENSDART00000133342 Nonsense 59 169 3 3
ENSDART00000134240 None 174 195 6 6
ENSDART00000134972 None 140 161 4 4
ENSDART00000138991 Nonsense 67 177 3 3

The following transcripts of ENSDARG00000019345 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 15621582)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 15536615
GRCz11 13 15667607
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCCATTCCTGTTGTGCTTCWTTTAAKAGTCGCCATGTATCTGGGGATCAG[C/T]AGAAAGATGAAGGGAAAGATGGAAAAGACGGRAAACCCCGCTCTCTCCGT
Long Flanking Sequence:
AAGCAGTTTAAAAAAAATTTAAAAGCCGTTTTAAGGTAAAAATTATGTTTTTTGATTAGCCTACAGAACAAACCATTCTTATACAATAACTTGCCTAATTATCCTATAAGAGCTATAAGTTCATTGTTTTTATTTATTTTAAATTAATAATAATGTGAAAAGCAAAACTTTTTGTACTTTTCACTTCTATTGTCACTGTATAGAAGTCTTGAAAAACATCAAGTACATATTATGTTCTGTCATCATTACAAAAATAAAAGAAATCGGTTATTAGAAATGAGTTATTAAAACTATTATGTTTAGAAATGTTTAAAAAATCTCTGTTAAACAAATTGGGGAAAAAATAAAAAAGAGGGGGCTAATAATTCTGACTAACTCTCTGTTTGTGTGTGTGTGTGTGTGTGCGTGCGTGCTTTTCTTAATCCATTGCTTAACCCTTCTCTCTCCCCCCCCATTCCTGTTGTGCTTCATTTAATAGTCGCCATGTATCTGGGGATCAG[C/T]AGAAAGATGAAGGGAAAGATGGAAAAGACGGGAAACCCCGCTCTCTCCGTTTCACCTGGAGTATGAACACCACCAGCACTATGGAACCAGCAGACATCATTAATGAGATTCGCACAGTTCTGGATGCCAACAGCTGCAGTTACCAGCAACGTGAATGCTTTCTGCTTCTGTGTGCCCATGGCGACTCTCACACCGACAGCCTTGTCCAGTGGGAGATGGAGGTGTGCAAACTGCCCCGGCTCTCACTTAATGGTGTCCGTTTTAAGAGGATATCTGGCAACTCCATCGCTTTTAAAAACATTGCTTCCAAAATTGCAGGCGAACTCAAGCTATGAATATATCTTTATCTACACAGAGGAATTTATGATTCAGTTCAGTATAGGCAAACCAGTTAAGCTGTACAATCGTAAAGTAGCAGTTTACATTTTTTTTATGAACCACTTACATGTATTTGAAAAACTGTATATATTTTAACATTGCTTAAAGCAATAATTTCTTAA
Associated Phenotype:
Not determined