Busch Lab

ZMP

bc2

Ensembl ID:
ENSDARG00000053979
ZFIN ID:
ZDB-GENE-040426-2922
Description:
Charged multivesicular body protein 2a [Source:UniProtKB/Swiss-Prot;Acc:Q7ZW25]
Human Orthologue:
CHMP2A
Human Description:
chromatin modifying protein 2A [Source:HGNC Symbol;Acc:30216]
Mouse Orthologue:
Chmp2a
Mouse Description:
chromatin modifying protein 2A Gene [Source:MGI Symbol;Acc:MGI:1916203]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa22108 Nonsense Available for shipment Available now
sa8643 Nonsense Mutation detected in F1 DNA Not yet available
sa4469 Essential Splice Site F2 line generated Not yet available

Mutation Details

Allele Name:
sa22108
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076103 Nonsense 38 220 2 6

The following transcripts of ENSDARG00000053979 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 28600864)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 26938473
GRCz11 12 27029833
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTAAATAGAGCCATGCGGGATCTAGACAGAGAACGGCAGAGACTGGAG[C/T]AGCAGGAAAAGAAAATAATCGCAGACATAAAAAAAATGGCCAAACAAGGA
Long Flanking Sequence:
AGCCCCAGCTGAACCAGTAGGCATTTCTCTGTCGAGTTTCCATGTTCTCCCCTTGTTGGCGTGGGTTTCCTCCAAAACGCACTATGCACTATGGGTGAATTGATTAAACTAAGTTGGCCGTAGTGTTTGTGTGTGGATAAGAGTGTATAGGTGTTTCCCAGTACTTCGTTACTGCTGAAAGGGCATCCACTGTGTAAAACATATTCTGGATAAGTACTCTCCAATTGAGTAAATAATGTGAAATAATGCGACCCATGATGAAAAAAAGATACTAAGCCGAAGGAGCATAAATGAATGACTTAAGTGCCCTCTAATGCCATTTGGATGTTTAACAGATCATAGAAACACTTAAAATTGTCCTCCTAATTGCTCTCTATTTTGTTCGTCAGATGGAGTTCCTGTTTGGAAGGAGAAAGACTCCTGAGGAGATGCTCAGACAGAATCAAAGAGCATTAAATAGAGCCATGCGGGATCTAGACAGAGAACGGCAGAGACTGGAG[C/T]AGCAGGAAAAGAAAATAATCGCAGACATAAAAAAAATGGCCAAACAAGGACAGATGGTAATGAGGTGTCATTTGATATTTGGTTGACTTTTTTACATTCATTTACAAGCAATATTCTTTCTCCTGTAGGATGCTGTAAAGATCATGGCTAAGGATTTGGTTCGTACAAGACGATATGTTAAGAAGTTCATCATGATGAGAGCCAATATTCAAGCTGTCAGCCTTAAAATTCAAACCCTCAAATCAAACAACAGCATGGCGCAGGCCATGAAAGGAGTCACCAAAGCTATGGCCACCATGAACAGACAGGTACTGTACATCCGCTAAAAAGTCCTGCCAACAGATAGTTTGTTCTTACGCGTGCGTTGATATTTATTCCTTTTTTCTCTTAATACAGTTAAAGTTGCCACAGATCCAGAAGATCATGATGGAGTTTGAGCGCCAAAGTGAAATCATGGACATGAAGGAGGAGATGATGAATGATGCAATTGATGATGCGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8643
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076103 Nonsense 105 220 3 6

The following transcripts of ENSDARG00000053979 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 28600591)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 26938200
GRCz11 12 27029560
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTAAAATTCAAACCCTCAAATCAAACAACAGCATGGCGCAGGCCATGAAA[G/T]GAGTCACCAAAGCTATGGCCACCATGAACAGACAGGYACTGTACAKCCGC
Long Flanking Sequence:
AAGCCGAAGGAGCATAAATGAATGACTTAAGTGCCCTCTAATGCCATTTGGATGTTTAACAGATCATAGAAACACTTAAAATTGTCCTCCTAATTGCTCTCTATTTTGTTCGTCAGATGGAGTTCCTGTTTGGAAGGAGAAAGACTCCTGAGGAGATGCTCAGACAGAATCAAAGAGCATTAAATAGAGCCATGCGGGATCTAGACAGAGAACGGCAGAGACTGGAGCAGCAGGAAAAGAAAATAATCGCAGACATAAAAAAAATGGCCAAACAAGGACAGATGGTAATGAGGTGTCATTTGATATTTGGTTGACTTTTTTACATTCATTTACAAGCAATATTCTTTCTCCTGTAGGATGCTGTAAAGATCATGGCTAAGGATTTGGTTCGTACAAGACGATATGTTAAGAAGTTCATCATGATGAGAGCCAATATTCAAGCTGTCAGCCTTAAAATTCAAACCCTCAAATCAAACAACAGCATGGCGCAGGCCATGAAA[G/T]GAGTCACCAAAGCTATGGCCACCATGAACAGACAGGTACTGTACATCCGCTAAAAAGTCCTGCCAACAGATAGTTTGTTCTTACGCGTGCGTTGATATTTATTCCTTTTTTCTCTTAATACAGTTAAAGTTGCCACAGATCCAGAAGATCATGATGGAGTTTGAGCGCCAAAGTGAAATCATGGACATGAAGGAGGAGATGATGAATGATGCAATTGATGATGCGATGGGAGATGAAGATGATGAAGAGGAGAGGTGAGCATGAATAAATGTACATTTTTATGAATATTTGCTAATTGACACCAACACTTTTTGCATTATTCTTGTAATGTAGTAAAATCAATACTTGAAATCAAGTAAAATATTATTTAATTAAAACCCGTGTCTGAATATACAGTTGAAGTCAGAATTATTAGCCCCCTGTATATTTTTTCTCTCCCAATTTTTGTTTAACGGAAAGGTTTGTGTAATAGTTTTAATAACTGATTTCTTATTTTTCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa4469
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000076103 Essential Splice Site 116 220 None 6

The following transcripts of ENSDARG00000053979 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 28600554)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 26938163
GRCz11 12 27029523
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCAGGCCATGAAAGGAGTCACCAAAGCTATGGCCACCATGAACAGACAGG[T/C]ACTGTACAKCCGCTAAAAAGTCCTGCCAACAGAKAGTTTGTTCTTACGCN
Long Flanking Sequence:
CTAATGCCATTTGGATGTTTAACAGATCATAGAAACACTTAAAATTGTCCTCCTAATTGCTCTCTATTTTGTTCGTCAGATGGAGTTCCTGTTTGGAAGGAGAAAGACTCCTGAGGAGATGCTCAGACAGAATCAAAGAGCATTAAATAGAGCCATGCGGGATCTAGACAGAGAACGGCAGAGACTGGAGCAGCAGGAAAAGAAAATAATCGCAGACATAAAAAAAATGGCCAAACAAGGACAGATGGTAATGAGGTGTCATTTGATATTTGGTTGACTTTTTTACATTCATTTACAAGCAATATTCTTTCTCCTGTAGGATGCTGTAAAGATCATGGCTAAGGATTTGGTTCGTACAAGACGATATGTTAAGAAGTTCATCATGATGAGAGCCAATATTCAAGCTGTCAGCCTTAAAATTCAAACCCTCAAATCAAACAACAGCATGGCGCAGGCCATGAAAGGAGTCACCAAAGCTATGGCCACCATGAACAGACAGG[T/C]ACTGTACATCCGCTAAAAAGTCCTGCCAACAGATAGTTTGTTCTTACGCGTGCGTTGATATTTATTCCTTTTTTCTCTTAATACAGTTAAAGTTGCCACAGATCCAGAAGATCATGATGGAGTTTGAGCGCCAAAGTGAAATCATGGACATGAAGGAGGAGATGATGAATGATGCAATTGATGATGCGATGGGAGATGAAGATGATGAAGAGGAGAGGTGAGCATGAATAAATGTACATTTTTATGAATATTTGCTAATTGACACCAACACTTTTTGCATTATTCTTGTAATGTAGTAAAATCAATACTTGAAATCAAGTAAAATATTATTTAATTAAAACCCGTGTCTGAATATACAGTTGAAGTCAGAATTATTAGCCCCCTGTATATTTTTTCTCTCCCAATTTTTGTTTAACGGAAAGGTTTGTGTAATAGTTTTAATAACTGATTTCTTATTTTTCTAGTTTTAATAAAACATTTATTTTATCTTTGCCATGATG
Associated Phenotype:
Not determined