Busch Lab

ZMP

uba3

Ensembl ID:
ENSDARG00000057987
ZFIN ID:
ZDB-GENE-040426-2825
Description:
NEDD8-activating enzyme E1 catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:Q7ZVX6]
Human Orthologue:
UBA3
Human Description:
ubiquitin-like modifier activating enzyme 3 [Source:HGNC Symbol;Acc:12470]
Mouse Orthologue:
Uba3
Mouse Description:
ubiquitin-like modifier activating enzyme 3 Gene [Source:MGI Symbol;Acc:MGI:1341217]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa13986 Nonsense Available for shipment Available now
sa21878 Nonsense Available for shipment Available now
sa9776 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa13986
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000080752 Nonsense 251 462 10 18
Genomic Location (Zv9):
Chromosome 11 (position 18292720)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 17658556
GRCz11 11 17793191
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGTGCACTATAGCGTCTATGCCACGGTTACCCGAACATTGTGTTGAAWA[T/G]GTACGCATGYTGCTGTGGCCCAAAGAAAAGCCCTTTGGAGGTACAATATG
Long Flanking Sequence:
TTTTTGCATAGAATTCCACATAGTCGTCTGTGGCCTGGACTCTGTTATCGCCAGAAGATGGATGAACGGCATGCTTGTATGTCTCATAAACATCCAAGAATCTATTAATAGATATGTTTAGATCTAAAATCCATTCATTCATTAATTAAGTAGAGTGTTTCTATTCATTGAGAAGTACATATAGTCTATGCATTTACCTTTGTCAGCTCTCCCTGCTGATTTATGAAGATGGAGTCCTGGACCCCAGCTCTATTATTCCACTAATAGATGGTGGCACAGAGGGCTTCAAGGGCAATGCCCGGGTCATTCTTCCAGGAATGACAGCCTGCATTGATTGCACTCTGGAGCTCTACCCCCCACAGGTGCATTTTGGGATTTTTTGTGTTAAGTTGAAGTTTCAAAGCTTTTTTGTCATGCTCATTTCTGCGCCCTACACAGATCAACTTCCCGATGTGCACTATAGCGTCTATGCCACGGTTACCCGAACATTGTGTTGAATA[T/G]GTACGCATGCTGCTGTGGCCCAAAGAAAAGCCCTTTGGAGGTACAATATGAGCTGATTGATTGGAATTTTTGGTTGTATTGCTAGCAGGTAATCTACTGTATTTCAGATATGGCTTTTTTGTTCTTCAGATGGTGTGGTTCTAGATGGAGATGACCCAAAGCACATCCAGTGGGTGTATCAGAAATCTTTGGAGAGAGCGGCTGAGTTCAACATCACTGGGGTCACTTACAGACTCACCCAGGGTGAGTGAGATGCCCTGTTCAATGGATCTTCATCAGGGATTTTTAAAAGCATCTCTTTTATTGACTTTAGGGCTGTAATTGTGCACATATTCATAATGAACGATTTTGATACAGGTCTTAGGGGCTGATCACAATGAACATGTTTTTCCGTGCTAAAACACGAGGCGCACCATATTTTCTTCTTTGTTGACGAGAAAAAAGAAGCGCTTTTTGCTAGGCAACAACTGAATCAGCTGTGTATTGTGCGAGAGTGTTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21878
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000080752 Nonsense 326 462 13 18
Genomic Location (Zv9):
Chromosome 11 (position 18288913)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 17654749
GRCz11 11 17789384
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAAATACTATTTGCTTTTTTTCCTGCATGTTTCAGCTGCTTGCGCCACA[G/T]AGGTTTTCAAAATTGCCACAAGGTAAGTTATAATATAGTTCTTTAAAAAG
Long Flanking Sequence:
GACAGGTGCTAACATTGTCCTAACTGATGCTCAACACACAAATCTGTTAAAATCTCAAAAAAGTACTCTGGTTTCTTGAACCTTTAATGCTCAAAGAACTTTACTAGATATTATACAGTACACCTCCCAACCAATAATCACAAGCTAGACAAGAAGTGTTTCTGTTAATTTTGATAAGAAATGAGGTCTTTCCAATTCTGTCCACTTTATCAAACAATAAATGCTATTTGGTTTGGCAATATAATGTTCAGGTTCAGTCTTTTTCCAAAAAGTCTAAATCAAGTTCACACAATTGTACTTGTTGATGTAAAATCACATCCTGTTTTTCAGGGGTTGTGAAGCGAATAATTCCTGCTGTGGCTTCTACAAATGCTGTCATTGCTGGTATTCTGACATTACAAATAATCTCTGGTTTTATTGTGCATTTTTTCAGTAAGTTGAGCGATAACTGTAAATACTATTTGCTTTTTTTCCTGCATGTTTCAGCTGCTTGCGCCACA[G/T]AGGTTTTCAAAATTGCCACAAGGTAAGTTATAATATAGTTCTTTAAAAAGAGCTTTGAATTCAGCATTTATTGACATATTTATTCTGTTCCCGAACAGCGCTTATGTTCCCTTGAACAACTACCTGGTGTTTAATGATGTCGACGGGCTGTACACATACACCTTTGAAGCAGAAAGAAAGGTTAGTAACTTGAACAGCATATGCTAAATGCTATAAATGTTTGAATGTGGATACAGCTGAAATGTTGTCCATGTTGTATTTGAAGGAGAACTGTTCTGCGTGCAGTCAGGTGCCACAGGACATGCAGTTCACACCGTCAGCTAAACTACAGGAGGTTCTGGACTACCTGACTGAGAACGCCTCTCTGTGAGACACTCACTGAATTAAATGCTTTACAGTTATTTGCATTGAAATCTCTTATTTCTTTATCATTGTCCTACAATATGTGTACCAATGCATAAAGCGTATAAAATAGTAATACTGTAAAACTGTGAACTTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9776
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000080752 Essential Splice Site 433 462 17 18
Genomic Location (Zv9):
Chromosome 11 (position 18286987)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 17652823
GRCz11 11 17787458
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGCATCTATTGAAGAAAGAACACGACCTAATCTGAGCAAAACACTGAAAG[G/A]TGAATTAAAGTTCTTTCCTGGTTAATAAANNNATATCTCATTTTATAGKTTAC
Long Flanking Sequence:
TGTAAACTTTATACTCAACGTTGTATAGATTTAGTCTGAAATGCAGTATAAAATACACTTGCTATTAAATTACTAGTACACTATAAAGAAGCAACAACAAAAACTAAATAAAAGCTTAATGTCTTTCTCCTCTATTAAGCAAAGTGCAGTATACAGCAGGAATCTGCCTCAGTATTAATTCCCTTTGCACGTAATGCTCCTTGTTTTTTAGATTAATAATAAAATATTGTAAATGTCAGTCATACAATTTTTTTTTTTTTTTATATTTTCGTTTATAATAACGCTGTTTTCTCCTCCTAGCCAAATGAAGTCTCCTGCAATCACTACAACTTTGGATGGAAAAAACAAAACTCTGTATTTACAGGTTAAAAGCTTTTCTAACATGATTTGATTACTGAGTTTCAAGAGTTTGACTGCATTTGAATCTCTTTGGTTTTACTTTCAGACTGTAGCATCTATTGAAGAAAGAACACGACCTAATCTGAGCAAAACACTGAAAG[G/A]TGAATTAAAGTTCTTTCCTGGTTAATAAAATATCTCATTTTATAGTTTACTGTGATTGTATAACTTGAAATGGCTAAATTGATCCCTTAACAAATAAACAGTAAAGTAAGTAGATAAAGCTAATTTGTTGCCAAATGGCCAATCAAAAATAGTCCAATCATACCAAAATTCTAAGTATGCCATTTACATTTGTAAAGTGCATATTTCATATCAGTCTATGCATTATACACTGTTTCTTTTATGGAAATAATTAGATATTAATAATTTTAAAGACTACTTTTTTTTTCTTTCATGAATAAAATCAAGTCTCTCATGTGCCACCTTGTTATATAATGGATGTTGGCGGGCAAATGCCAAACAGCTTTGGCGGAATTAGACCCCAAACTTGTAAAATATATTTTAAAGTAGAGATATTTTAACAATCTAAAATAAACATTCCAGATATTCTTAATTAAACTGTAATTGACTTTATGTAGATTACATGAGCTTTGTTAGTTATT
Associated Phenotype:
Not determined