ZMP
zgc:100824
Ensembl ID:
ZFIN ID:
Description:
Diphosphomevalonate decarboxylase [Source:UniProtKB/Swiss-Prot;Acc:Q5U403]
Human Orthologue:
MVD
Human Description:
mevalonate (diphospho) decarboxylase [Source:HGNC Symbol;Acc:7529]
Mouse Orthologue:
Mvd
Mouse Description:
mevalonate (diphospho) decarboxylase Gene [Source:MGI Symbol;Acc:MGI:2179327]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa19000 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa21857 | Nonsense | Available for shipment | Available now |
| sa21856 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa19000
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000110966 | Essential Splice Site | 225 | 354 | 6 | 9 |
Genomic Location (Zv9):
Chromosome 11 (position 11198133)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 31082385 |
| GRCz11 | 18 | 31060639 |
KASP Assay ID:
2260-3977.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCACATCTGGAATGCACACAAGTGTGGAGACGAGCCACCTTCTGAAGG[T/C]AAATTGTTTAATCAATTATGTTCTTATGGGATGTATTTTTGCAATATCAT
Long Flanking Sequence:
TTCCAAAATTCAATACAGAACTTTATTATTAAAAAATATCAGTTCTAAAGGTTTTAGTATCACCTTCACCTAAAATAAGATTTAAGCTTGAACCTGTTACAATTACTGCAGAATGCGGTTCAAAAAAGCAAACAAGTTTTACCTTTTAAATATGTCTTGACTATGTCCAAAGTTTGTTTTAAGTAAACTATTGTTTGATGGGTGAAATCTCACAAAATATATATATTTATATTTTACAAATCATGAATAGAAATGTCCTGCAAGATGCATTATAGAGGAAATCTCCGCCTCCAAATGTGAACTTACTAGTGATCAGTTACAGCAATTTAAAGTGTACAATTTCTCTCATATAGATGCAGTTTTTCCTAAGAAATGGTAGTCAGTTACTCGTTTTATTGTCTAATATGAAAATGTTTTTTCATAGGTCAGTGCTGAGCAGAAATCTGTTGGCAGCACATCTGGAATGCACACAAGTGTGGAGACGAGCCACCTTCTGAAGG[T/C]AAATTGTTTAATCAATTATGTTCTTATGGGATGTATTTTTGCAATATCATAAAACTAAGTGTTGTTTTGCTTATCGGTATGCAGGTAATCAGCAAAGTAATAAATAAATGGCAATCTCTTTTTTTGCACCGAGGTGGTTTTTGTTACAGAAAATGTCATAGTGCCTGAAGTGTTACCTCTAAGATTTTTTCCAGTTGTGGCGGCAGGCCTTTTACACAAATTTATGAACTACCTGTGGCGTTATTTCAATGACAATTGGAGAAATGTCGTGAGCACAATATTACAAGTAGAGATCGCATTTATGTGCAATACGAACGTGCTTGCGCGCCAATTTTCTCTTGCACGCCCCCTCAAATATACGCTGCTCAAGCGCAGATCTTCTTGTGCACTCTTAAATAAACGATACTGAAATCCGATATAGCGTGTTTATTTAGTGAGTGTGTTTTCAACATTTAATAGATTTGCTAGGAATATTTATGAATGTCTCCAATAGACTTACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21857
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000110966 | Nonsense | 296 | 354 | 7 | 9 |
Genomic Location (Zv9):
Chromosome 11 (position 11193911)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 31086607 |
| GRCz11 | 18 | 31064861 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATCGCACCAGATCATCAGTCTTGTACACCGCTACAACCAGTACTATGGC[G/T]AGACCAGGGTGAGCATAATATAACAATATTTAGAGATTTCACTAACATTT
Long Flanking Sequence:
GTGAGAAACCCTTTTTTCATAAAATCCCATCATAAAAAATCTAACTTTTCTTTTACTCCAATAAAACATGACAAAGTCTGGGTCACTCCAAAATGACATAAAGGTGTAACTTGCTGAAAGAATCAATAAAAACTCCTCACCAGTAATGCATTTACAGAGTGACTACAAAACAAAATAAGAAAGTTAACATCTTCTGCAATTTACCAGTGCAATGCAAGTAAGGTATTCATGTTATTGTGATGTGTATAAGTTTGTAGGTATAAAAGTTCATATGCTATACTTTTCCACAGTACAGAGCAGATGCTGTGGTCCCCGGTCGTATGGAAGAGATGATAAGGGCAATTCACCTACGAGACTTTCCAAAATTTGGTGAGCTGACCATGAAAGACAGTAATCAGTTTCATGCCATCTGCCTGGACACCTACCCACCTATATTCTACCTGAACAACATATCGCACCAGATCATCAGTCTTGTACACCGCTACAACCAGTACTATGGC[G/T]AGACCAGGGTGAGCATAATATAACAATATTTAGAGATTTCACTAACATTTATGATAATGAGAATTTCGTGCTTAAAAGAGCCACCTCAGCAGATATTATGACTTATCAACCAGAACAGAAACAAAAGGTTGACTGAGAAAAGCAGAAGTAGGACACAGTGATAAAAAAAACGTTGTACTTTTGTAAATTAGACCTGTGGTTTTACACTTACCACATCTGGAAGCTTACTGCTAAGCAACTTCTTAACAGATAATTTACCCAATTATTAATATTCTGCCATTGTTTATGTCTCAGGCCTCTGATTTACAAAAGTTAAGTGATCTGACCAAGCAAATAACATTGTGAGGCCGGGACACACCAAGCCGACGTTCCGGTTCTTTAAACTGGATTTATACTTCACCTGGCTCTGCACCAGCACCACCAGTCACACCCTATTCATACAGGGCTTCAGCATCAACGCTTGACAGAGTGTGTCTGAAGTTGGAGCTAACGTGATCGTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21856
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000110966 | Nonsense | 317 | 354 | 8 | 9 |
Genomic Location (Zv9):
Chromosome 11 (position 11190591)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 18 | 31089927 |
| GRCz11 | 18 | 31068181 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATACCTTTGATGCTGGTCCTAATGCAGTTATTTACTCCTTGCAAGACTA[C/A]TTACCAGAGTTTGTAGAGGTGGTTCGCCATTTCTTTCCCCCTAAGGTCAA
Long Flanking Sequence:
GAGGGAGCAGTTGGGCCATGATGAAAACTTCACTAAACAGTAAGGGGTTAACAACAAGTGAATAAATAACAGAAACAGTCAGGTGTATGAAATAATCTTGTCAAAAAGACAAACAAGATTATTTTGATTACCTCATTGGTAGTTTATTACAAGGAGGCATTATGTTAATATAATGTTTACATTATATCAAGGCATACAAGTCTTGATACCCTTAAACTGTTTGGTGCTGTCTTGCAACTAAATAATAAGTAGATGCACTCAGTGTTTTTTGTTTCCGTCAGCTTTTTAGCTTTTTGTGCAAATGAAGAGTTAAAGAAATAGTTCATCATTTACTCATGACATTTCTACATTGTCCCTTCTATGTCCCTTTTGTAAAAGTCAGTATGTTTTTTGAGTTTATAGTGTAAAGTGAATGATGTATTTTCACCTTCTGTCTTGCTGTAGGTGGCATATACCTTTGATGCTGGTCCTAATGCAGTTATTTACTCCTTGCAAGACTA[C/A]TTACCAGAGTTTGTAGAGGTGGTTCGCCATTTCTTTCCCCCTAAGGTCAATGAAGAAGAGTAAGTTGCTTAAATCAAGCATGTTGCTGTTACAGTATTACTAGTTTAAAAACAAACTTTGCAGCTCTTTACAGTACACAGAGACACAATGTTGTGATCAGAACTATCAAATGCTTTGATTTACAGATTTTTCAAAGGTCTACCAGTGTGCACAGCTGACCTCTCTGAGGAGATGATAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATA
Associated Phenotype:
Not determined